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Browse the failure-mode index

20,261 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

COVID-19 infection prior to the onset of type 1 diabetes does not impair beta-cell function: a two-year nationwide follow-up study.

Bjerregaard-Andersen M, Hostrup PE, Kolnes KJ et al. · 2026 · BMC endocrine disorders

Background A possible association between infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and type 1 diabetes (T1D) development has been reported. Whether SARS-CoV-2 infection affects beta-cell loss in T1D…

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Negative / Null Result ReportMedicine

Do Preoperative Intra-Articular Steroid Injections Affect the Choice of Surgical Procedures for Thumb Carpometacarpal Osteoarthritis?

Komura S, Hirakawa A, Hirose H et al. · 2026 · The Journal of hand surgery

Purpose This study investigated the influence of preoperative intra-articular steroid injections on surgical outcomes of trapeziectomy with ligament reconstruction and tendon interposition (LRTI) arthroplasty and arthrodesis and aimed to…

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Negative / Null Result ReportMedicine

Effects of the Paleo diet on resting metabolic rate in handball players.

Pięta A, Mazur-Kurach P, Maciejczyk M et al. · 2026 · Scientific reports

The Paleolithic diet (PD) has positive effects on health status and body composition. The Paleo diet has been also used to assess the effects on handball players performance but the association of adherence to PD and resting metabolic rate…

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Negative / Null Result ReportMedicine

True metabolizable energy, standardized amino acid digestibility, phosphorus digestibility, and phosphorus bioavailability of fermented soybean meal and fermented full-fat soybeans fed to chickens

Cristobal M, Utterback PL, Stein HH et al. · 2025 · Poultry Science

The objective was to evaluate the nutritional value of conventional soybean meal (SBM-CV), fermented SBM-CV (FSBM), full-fat soybeans (FFSB), and fermented FFSB (FFFSB). In Experiments 1 and 2, two precision-fed rooster assays were…

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Negative / Null Result ReportMedicine

The effects of furosemide on pulmonary transmural pressure and exercise-induced pulmonary hemorrhage in supramaximally exercising thoroughbred racehorses.

Massie S, Léguillette R, Jones JH et al. · 2026 · Journal of veterinary internal medicine

Background Maximal intensity exercise in equine athletes induces pulmonary capillary stress failure and exercise-induced pulmonary hemorrhage (EIPH) secondary to excessive transmural pressure (Ptm). Furosemide decreases EIPH severity and…

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Negative / Null Result ReportMedicine

Impact of silver nanoparticles on leachate from pilot-scale reactors simulating a municipal solid waste landfill.

Bonatto IDC, Cavali M, Belli IM et al. · 2026 · Waste management & research : the journal of the International Solid Wastes and Public Cleansing Association, ISWA

The generation of municipal solid waste (MSW) has risen sharply, posing increasingly complex environmental challenges, particularly in its final disposal in landfills. Among the various contaminants present in MSW, emerging pollutants such…

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Negative / Null Result ReportOpen accessMedicine

Nitrergic neurotransmission within the lateral hypothalamus modulates cardiovascular responses to stress in rats.

Silva GA, Reis-Silva LL, Gomes-de-Souza L et al. · 2026 · Pflugers Archiv : European journal of physiology

The lateral hypothalamus (LH) is a key brain region involved in integrating cardiovascular and autonomic components of the stress response, yet the local neurochemical mechanisms governing these functions remain poorly understood. This…

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Negative / Null Result ReportMedicine

Neural correlates of temporal interference between faces.

Lidborg LH, Kohen Tuncer D, Burton AM et al. · 2026 · Biological psychology

Theoretical models of face processing incorporate within-pool inhibition - a mechanism by which representations compete with one another to support recognition. However, direct evidence for these inhibitory mechanisms is sparse in studies…

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Negative / Null Result ReportMedicine

Acute effect of impact and resistance exercise on Wnt signaling modulators, bone and cartilage metabolism.

Boxer B, Zhang Z, Folland JP et al. · 2026 · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Impact and resistance exercise have potent osteogenic effects and may positively affect cartilage through tissue deformation. These effects may be mediated through inhibitors of Wnt signaling, such as sclerostin and Dickkopf WNT signaling…

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Negative / Null Result Report

Fungal-bacterial interaction unaffected by heatwave conditions

Moreno-Druet M, Pardaens S, Soudzilovskaia NA et al. · 2026 · Preprint

Climate change is reshaping soil microbial communities, yet the impact of warming in bacterial-fungal interactions (BFIs) remains underexplored. We investigated whether heatwave temperature influence BFIs and the mechanism supporting the…

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Negative / Null Result ReportMedicine

Outcomes and Complications After LUMiC<sup>®</sup> Endoprosthetic Reconstruction of Periacetabular Defects-A Retrospective Cohort Analysis.

Niemann AS, Ramon R, Mayor J et al. · 2026 · Life (Basel, Switzerland)

(1) Background: The reconstruction of periacetabular defects after tumor resection remains one of the most challenging procedures in orthopaedic oncology. The modular LUMiC ® system was designed to improve fixation stability and reduce…

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Negative / Null Result ReportMedicine

Sex, Race, and Ethnicity in National Institutes of Health Career Development Award Submissions and Success: A 20-Year Retrospective Cohort Study.

Koumpias AM, Kirch M, Steppe E et al. · 2026 · Journal of women's health (2002)

Background Obtaining a National Institutes of Health (NIH) career development (K) award is a pivotal milestone for early-career faculty, contributing not only to individual career progression but also to the diversity of the biomedical…

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