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Browse the failure-mode index

19,902 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

The association between changes in muscle mass and function and mortality in individuals receiving peritoneal dialysis.

Wang L, Xue C, Zhu B et al. · 2025 · Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis

Background/objective Data in terms of how dynamic changes of muscle mass and function affect mortality in end-stage kidney disease (ESKD) patients undergoing dialysis have led to inconclusive results. The main goal of this research was to…

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Negative / Null Result ReportOpen accessMedicine

Ultrasound-Guided Versus Freehand Fine Needle Aspiration: A Comparative Study in Diagnosing Non-Salivary, Non-Thyroidal Head, and Neck Masses.

Rajamanickam SK, Prades Morera E, Agarwal A et al. · 2025 · Cureus

Background Fine needle aspiration cytology (FNAC) is widely used to evaluate head and neck masses, with both ultrasound (US)-guided and freehand techniques being employed. While US-guided FNAC is thought to enhance accuracy, freehand FNAC…

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Negative / Null Result ReportMedicine

Lack of controlled studies on snakebite prevention: a rapid review.

Rodrigo C, Gnanathasan A · 2024 · Transactions of the Royal Society of Tropical Medicine and Hygiene

Globally, snakebites cause an estimated 80 000-140 000 deaths annually. While there are evidence-based recommendations for managing snakebite victims, recommendations on the prevention of snakebites are limited to expert opinions. We…

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Negative / Null Result ReportOpen accessMedicine

High rates of benzimidazole-resistance-associated alleles in Haemonchus contortus and detection of resistance against macrocyclic lactones in strongylids from German alpaca herds.

Hinney B, Wiedermann S, Vaneev X et al. · 2024 · Parasites & vectors

The population of South American camelids (SAC) has been steadily growing in Europe, where they are confronted with the regional endoparasite population of ruminants. As there are no anthelmintic drugs registered for use against nematode…

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Negative / Null Result ReportOpen accessMedicine

A prospective cohort study produces inconclusive results in linking dietary calcium intake to overall and specific causes of mortality.

Le NT, Nguyen TG, Huynh NYN et al. · 2025 · Scientific reports

Dietary calcium's role in human health and disease prevention is inconclusive. We examined the associations between dietary calcium intake and the risk of overall and specific causes of mortality. A prospective cohort study was performed…

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Negative / Null Result ReportOpen accessMedicine

Concomitant Autoimmune Liver Disease and Hepatic Actinomycosis: A Diagnostic Challenge-Brief Report and Review of the Literature.

Manni G, Pambianco M, Sicuro C et al. · 2025 · International journal of molecular sciences

Hepatic actinomycosis (HA) and IgG4-related inflammatory pseudotumors are rare and often overlooked causes of liver mass, which can easily be misdiagnosed as primary liver cancer or metastasis. Diagnosis is arduous due to unspecified…

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Negative / Null Result ReportMedicine

No detectable impact of ALPS-treated water discharge on tritium levels in terrestrial waters of the upper Ota River catchment, Fukushima, Japan.

Sakuma K, Yoshimura K · 2026 · Journal of environmental radioactivity

Tritium ( 3 H) is the principal radionuclide remaining in ALPS-treated water discharged from the Fukushima Dai-ichi Nuclear Power Plant (FDNPP), and its potential environmental impact has drawn considerable attention. To evaluate possible…

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Negative / Null Result ReportOpen accessMedicine

Evaluating the Impact of a Molecular Diagnostic Algorithm on Tuberculosis and Nontuberculous Mycobacterial Infections in Newfoundland and Labrador, Canada.

Needle R, Yu Y, Soualhine H et al. · 2025 · Biomedicines

Background/Objectives : The diagnosis of Mycobacterium tuberculosis complex (MTBC) and nontuberculous mycobacterial (NTM) infections is accomplished by three main diagnostics methods: smear microscopy, culture, and molecular testing.…

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Negative / Null Result ReportOpen accessMedicine

A Study on the Visibility and Radiological Characteristics of a Normal Appendix in Patients Undergoing Non-contrast Computed Tomography at Teaching Hospital Jaffna, Sri Lanka.

Gobishangar S, Abiharan P, Jenil A et al. · 2026 · Cureus

Background The appendix is a vermiform structure with a variable position, length, and thickness. Imaging plays a critical role in diagnosing an inflamed appendix, with non-contrast computed tomography (NCCT) being an effective modality…

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Negative / Null Result ReportMedicine

Tooth wear and bruxism: A scoping review.

Bronkhorst H, Kalaykova S, Huysmans MC et al. · 2024 · Journal of dentistry

Objective This study presents a scoping review to determine the association between tooth wear and bruxism. Data A protocol was developed a priori (Open Science Framework (DOI 10.17605/OSF.IO/CS7JX)). Established scoping review methods…

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Negative / Null Result ReportMedicine

50 Hz magnetic field influences caspase-3 activity and cell cycle distribution in ionizing radiation exposed SH-SY5Y neuroblastoma cells.

Nieminen V, Martikainen MV, Kalliomäki S et al. · 2024 · International journal of radiation biology

Purpose Earlier evidence suggests that extremely low frequency magnetic fields (ELF MFs) can modify the effects of carcinogenic agents. However, the studies conducted so far with ionizing radiation as the co-exposure agent are sparse and…

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Negative / Null Result ReportOpen accessMedicine

ECG-Gated 4D-CTA Assessment of Intracranial Aneurysm Wall Dynamics and Longitudinal Size Change: An Exploratory Study.

Jankovič P, Chodzyński KJ, Vanrossomme AE et al. · 2026 · Neurology international

Background The risk stratification of unruptured intracranial aneurysms (UIAs) relies largely on static clinical and morphological parameters, which may not fully capture aneurysm-specific wall behavior. ECG-gated four-dimensional computed…

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Negative / Null Result ReportMedicine

Staphylococcal Cassette Chromosome <i>mec</i> (SCC<i>mec</i>) Natural Excision Frequencies and Its Contributing Factors in Variant SCC<i>mec</i> Type Prototypic Strains.

Mirza S, Fine L, McClure JA et al. · 2026 · Antibiotics (Basel, Switzerland)

Background Staphylococcus aureus acquires methicillin resistance genes through the SCC mec element. Although spontaneous SCC mec excision has been observed, its frequency, type-specific variation, and responsiveness to environmental…

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