Negative / Null Result Report
Macaulay C, Scheepers C · 2025 · Preprint
A Theory of Magnitude (AToM) (Walsh, 2003; Walsh, 2014) attempts to explain avisuo-spatial bias observed across magnitude processing domains (e.g., numerical, temporal).It proposes a generalised processing system which maps mental…
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Van der Snickt T, Ailliet S, Bassini S et al. · 2025 · Preprint
Enzyme-free isothermal amplification methods offer a promising alternative to enzymatic assays for nucleic acid detection, particularly in low-resource settings. The nonenzymatic isothermal strand displacement and amplification (NISDA)…
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Walleczek J, von Stillfried N, Schmidt S et al. · 2025 · Preprint
This metascientific project studied the replicability of Bem Experiment 1, which had claimed a precognitive effect, i.e., the ability to successfully guess the outcome of future random events (Bem. J Pers Soc Psychol. 2011;100: 407-25).…
View details →Negative / Null Result ReportMedicine
Li L, Wang Y, Du Z et al. · 2026 · Metabolism: clinical and experimental
Background and aims Targeting key enzymes in hepatic de novo lipogenesis (DNL) presents a promising strategy for treating hypercholesterolemia. However, the precise regulatory mechanisms governing hepatic DNL remain incompletely…
View details →Negative / Null Result ReportMedicine
Petersen Dias A, Orsel K, Gammariello CS et al. · 2025 · Research in veterinary science
Digital dermatitis (DD) is a polymicrobial, multifactorial hoof disorder with an undefined etiology, and existing animal models fail to induce a fast, standardized infection in bovine skin. This study explored bacterial inoculation methods…
View details →Negative / Null Result ReportMedicine
Willroth EC, Young G, Ford BQ et al. · 2025 · Psychological science
Certain emotion-regulation strategies (e.g., reappraisal) are associated with better well-being and are therefore seen as adaptive (health-promoting) strategies. However, it is unlikely that any strategy is adaptive regardless of context.…
View details →Negative / Null Result ReportMedicine
Argenbright CM, Scully IF, Flores D et al. · 2025 · The journal of pain
Pain is a multidimensional phenomenon, encompassing affective-motivational, cognitive-evaluative, and sensory-discriminative domains. Understanding these components is crucial for effective diagnosis and management, particularly in…
View details →Negative / Null Result ReportMedicine
Goldberg SB, Baldwin SA, Flynn AWP et al. · 2026 · Clinical psychological science : a journal of the Association for Psychological Science
While it is known that therapists vary in effectiveness, it is unclear what therapist-level characteristics predict this variation. We conducted a large-scale, preregistered study ( n = 97 therapists from the United States and Canada, n =…
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Adinugroho I, Bentall R, Stafford T · 2025 · Preprint
This is the first study to attempt replication of Banas et al (2023) on inoculation messages. The original experiment demonstrated that inoculation messages could stimulate resistance to anti-vaccine conspiracy theories. However, a gap was…
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Kakeya H, Umeno Y · 2025 · Preprint
Background Kayano et al. estimated the potential number of COVID-19 cases and deaths in Japan from February 17 to November 30, 2021, in a counterfactual scenario where no vaccination was implemented. Their model predicted 63.3 million…
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Stawiany K, Kozak K, Sokołowska Z · 2025 · Preprint
The study explores the hypothesis that individuals show greater sympathy towards coherent name-face pairs compared to incoherent pairs, replicating the effect observed by Barton and Halberstadt. A structured questionnaire was designed…
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Houben M, Rief W, Gärtner T et al. · 2024 · Preprint
Abstract Background: Depression is related to a reduced update of negative expectations in response to positive information. Here, we aimed to replicate that cognitive immunization (a cognitive devaluation of expectation-disconfirming…
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Whiteford KL, Baltzell LS, Chiu M et al. · 2024 · Preprint
Musical training has been associated with enhanced neural processing of sounds, as measured via the frequency following response (FFR), implying the potential for human subcortical neural plasticity. We conducted a large-scale multi-site…
View details →Negative / Null Result ReportMedicine
Zhou Y, Tse CS · 2025 · The Journal of general psychology
In English, head is associated with rationality and logic, whereas heart is related to feeling and emotionality. In Chinese, these head- and heart-related metaphors also exist. Could these head- and heart-related conceptual metaphors…
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Noel M, Suttapitugsakul S, Cummings RD et al. · 2024 · Preprint
Protein O-glycosylation is a critical modification in the brain, as genetic variants in the pathway are associated with both common and severe neuropsychiatric phenotypes. However, little is known about the most abundant type of O-glycan…
View details →Negative / Null Result ReportMedicine
Stüber AT, Heimer MM, Ta J et al. · 2025 · European journal of radiology
This study investigates the predictive capability of radiomics in determining programmed cell death ligand 1 (PD-L1) expression (>=1%) status in non-small cell lung cancer (NSCLC) patients using a newly collected [18F]FDG PET/CT dataset.…
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Centorame G, Warrington NM, Hemani G et al. · 2024 · Preprint
Background Breastfeeding is hypothesised to benefit child health and cognitive functioning by providing long-chain polyunsaturated fatty acids (LC-PUFA), which are essential for brain development. In 2007, Caspi et al. found evidence in…
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Wiesing M, Zimmermann E · 2023 · Preprint
Intentional actions produce a temporal compression between the action and its outcome, known as intentional binding. However, Suzuki et al. (2019) recently showed that temporal compression can be observed even without intentional actions.…
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Lloyd B, Wurm F, de Kleijn R et al. · 2023 · Preprint
Background Transcutaneous auricular vagus nerve stimulation (taVNS) is a promising brain stimulation method for the treatment of pharmaco-resistant epilepsy and depression. Its clinical efficacy is thought to depend on taVNS-induced…
View details →Negative / Null Result ReportOpen accessMedicine
Ahrens A, Liesefeld HR, Kinner J et al. · 2026 · Psychological research
In everyday life, we often generalize previously learned associations between our actions and their outcomes to novel, but similar situations. The present study aimed to conceptually and directly replicate results reported by Esser et al.…
View details →Negative / Null Result ReportMedicine
Wentura D, Gurbuz E, Paulus A et al. · 2023 · Journal of experimental psychology. Human perception and performance
When asked to judge or react to a facial emotional display of a person, people do not only take the emotion into account, but also other socially important features of the face, such as, for example, ethnicity (Kozlik & Fischer, 2020;…
View details →Negative / Null Result ReportMedicine
Beckner AG, Voss AT, Phillips L et al. · 2023 · Infant behavior & development
Two experiments were conducted to examine mental rotation in 6- to 12-month-old infants (N = 166) using a change detection task. These experiments were replications of Lauer and Lourenco (Lauer et al., 2015; Lauer & Lourenco, 2016), using…
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Bartsch LM, Musfeld P · 2023 · Preprint
The covert retrieval model (McCabe, 2008) postulates, that delayed memory performance is enhanced when the encoding of memoranda in WM is interrupted by distraction. When subjects are asked to remember stimuli for an immediate memory test,…
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Lucchi F, Lloyd B, Nieuwenhuis S · 2023 · Preprint
Background The vagus nerve is thought to be involved in the allostatic regulation of motivation and energy metabolism via gut-brain interactions. A recent study by Neuser and colleagues [1] provided novel evidence for this process in…
View details →Negative / Null Result ReportOpen accessMedicine
Abad-Malo D, Alvarado-Cando O, Karsilar H · 2025 · Journal of eye movement research
Our interaction with the world depends on our ability to process temporal information, which is a key component of human cognition that directly impacts decision-making, planning, and prediction of events. Visual information plays a…
View details →Negative / Null Result ReportOpen accessMedicine
Lorente P, Ruuskanen V, Mathôt S et al. · 2025 · Psychonomic bulletin & review
Recent studies have investigated resting-state, or baseline, pupil size as a general measure of cognitive abilities, based on the earlier finding that larger pupils might be predictive of higher general intelligence or working memory…
View details →Negative / Null Result ReportOpen accessMedicine
Van der Burg E, Jertberg RM, Geurts HM et al. · 2026 · Translational psychiatry
Traditional subjective measures are limited in the insight they provide into underlying behavioral differences associated with autism and, accordingly, their ability to predict diagnosis. Performance-based measures offer an attractive…
View details →Negative / Null Result ReportOpen accessMedicine
Ashburn-Nardo L, Moss-Racusin CA, Smith JL et al. · 2022 · Frontiers in psychology
The reproducibility movement in psychology has resulted in numerous highly publicized instances of replication failures. The goal of the present work was to investigate people's reactions to a psychology replication failure vs. success,…
View details →Negative / Null Result ReportOpen accessMedicine
Mura F, Catrambone V, Valenza G et al. · 2026 · Biological psychiatry global open science
Background Various cognitive and emotional factors shape our perception of time. Notably, individuals experiencing depressive symptoms often report changes in their time perception, characterized by a phenomenon termed depressive time…
View details →Negative / Null Result ReportOpen accessMedicine
Hawkes JA, Flygare AD, Moodie LWK et al. · 2025 · Analytical chemistry
Dissolved organic matter (DOM) is one of the most complex chemical mixtures known, with its chemical composition having long puzzled biogeochemists. Identifying the chemical structures within DOM is essential for unraveling its origins and…
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