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Browse the failure-mode index

20,261 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

What Is the Impact of Second Language Exposure and Intellectual Disability Status on Executive Function and Functional Communication Outcomes in Children and Adolescents With and Without Autism Spectrum Disorder (ASD)?

Hutchison SM, DiazPinzon N, Oberlander TF et al. · 2025 · Autism research : official journal of the International Society for Autism Research

Over the past 10 years, research has suggested no negative effect on second language exposure in children with autism spectrum disorder (ASD), yet, parents and professionals may be concerned that using a second language with a child with…

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Negative / Null Result ReportOpen accessMedicine

Immune Globulin

· 2006

Immune globulin G (IgG) is a normal component of breastmilk. Data from 2 mothers indicate that IgG concentrations in milk are normal or higher and IgM levels in milk are normal or lower during intravenous immunoglobulin (IVIG) therapy. The…

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Negative / Null Result ReportOpen accessMedicine

Repeated Tetrahydrocannabinol Injections Induce Tolerance but Do Not Disrupt Ongoing Behaviour Upon Withdrawal in Male and Female Rats With Inflammatory Pain.

Morgan MM, Hickey CM · 2026 · European journal of pain (London, England)

Background Many people use cannabis to self-medicate for pain. Little is known about the impact of pain on tolerance and spontaneous withdrawal to delta-9-tetrahydrocannabinal (THC), the primary psychoactive compound in cannabis. Our…

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Negative / Null Result ReportMedicine

Variation in Maternal Effort, Activity Budgets, and Feeding Behavior in Wild Saddleback Tamarins (Leontocebus weddelli) in Northwestern Bolivia.

Erb WM, Porter LM, Voyt R et al. · 2025 · American journal of primatology

Among primates, maternal infant care may vary in response to several factors including litter size, reproductive history, and health status. In cooperative breeders, maternal investment may also depend on the amount of help their group…

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Negative / Null Result ReportMedicine

Transition from classic to expanded Denver screening criteria for blunt cerebrovascular injury: lessons from a high-volume level I trauma center.

Casado-Ruiz J, Castaño-Leon AM, García-Escudero L et al. · 2025 · Journal of neurosurgery

Objective Blunt cerebrovascular injuries (BCVIs) are associated with significant morbidity and mortality. To identify patients with BCVI who were undetected using the classic criteria, researchers designed the expanded Denver screening…

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Negative / Null Result ReportMedicine

Childhood poverty and its impact on financial decision making under threat: A preregistered replication of Griskevicius et al. (2011b).

Gladstone JJ, Lehman M, Decker M · 2025 · Journal of experimental psychology. Applied

We investigated the influence of childhood poverty on financial decision making under threat by replicating the findings of Griskevicius et al. (2011b), which found that individuals from lower socioeconomic backgrounds tend to make riskier…

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Negative / Null Result ReportOpen accessMedicine

A Comparison of Vessel Density in Primary Open-Angle Glaucoma and Normal-Tension Glaucoma Patients Using OCT Angiography.

Zehavi-Dorin T, Kutzscher AE, Badr M et al. · 2026 · Clinical ophthalmology (Auckland, N.Z.)

Purpose To compare global peripapillary and perifoveal vessel densities between primary open-angle glaucoma (POAG) and normal-tension glaucoma (NTG) patients with the same glaucoma severity using optical coherence tomography angiography…

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Negative / Null Result ReportOpen accessMedicine

Cryoanalgesia to treat phantom limb pain following a trans-femoral (above-knee) amputation: a randomized, sham-controlled pilot study.

Ilfeld BM, Finneran JJ, Abdullah B et al. · 2026 · Regional anesthesia and pain medicine

Background A previous clinical trial applied percutaneous cryoneurolysis to lower limb amputees with phantom pain. The primary outcome measure was negative, but a secondary analysis suggested that patients with a below-knee amputation…

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Negative / Null Result ReportMedicine

Face masks and protection against COVID-19 and other viral respiratory infections: Assessment of benefits and harms in children.

Sandlund J, Duriseti R, Ladhani SN et al. · 2025 · Paediatric respiratory reviews

Mask mandates for children were implemented at schools and childcare centers during the COVID-19 pandemic, and the US continues to recommend masking down to the age of two in certain settings. Medical interventions should be informed by…

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Negative / Null Result ReportOpen accessMedicine

Progestogen supplementation to prevent miscarriage: Evidence and controversies.

Saccone G, Berghella V, Gulersen M et al. · 2026 · International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

Progesterone plays a key role in the establishment and maintenance of pregnancy and its deficiency has been associated with early pregnancy loss. Progestogen supplementation has therefore been widely investigated as a preventive strategy…

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Negative / Null Result ReportMedicine

Semantic facilitation in blocked picture categorization: Some data and considerations regarding task selection.

Wöhner S, Luckow J, Brandt M et al. · 2024 · Journal of experimental psychology. Human perception and performance

Semantic context effects in picture naming and categorization tasks are central to the development and evaluation of current models of word production. When pictures are named in a semantically blocked context, response latencies are…

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Negative / Null Result ReportMedicine

Do uncontrolled processes contribute to evaluative learning? Insights from a new two-US process dissociation procedure and ambivalence measures.

Béna J, Lacassagne D, Corneille O · 2025 · Quarterly journal of experimental psychology (2006)

The contribution of uncontrolled processes to evaluative learning has been examined in evaluative conditioning procedures by comparing evaluations of conditioned stimuli between tasks or within tasks but between learning instruction…

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