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20,261 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Proactive versus standard support of labor in the latent phase - A randomized, controlled clinical trial.

Larsen M, Underdal M, Salvesen Ø et al. · 2025 · Sexual & reproductive healthcare : official journal of the Swedish Association of Midwives

Objective Long latent phase of labor with subsequent prolonged total labor duration increases the risk of obstetric interventions and complications. We explored whether Proactive Support of Labor (PSL) compared to Standard Support of Labor…

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Negative / Null Result ReportMedicine

Enhancing Removable Partial Denture Hygiene: Investigating Mucolytic Agents and Biocides for Disrupting Biofilms and Improving Antimicrobial Efficacy.

Moraes LGDS, Oliveira VC, Macedo AP et al. · 2025 · The International journal of prosthodontics

Purpose To evaluate the antibiofilm action of 2.5 mg/mL peracetic acid (PA), 0.5 mg/mL cetylpyridinium chloride (CPC), and 160 mg/mL N-acetylcysteine (NAC) against multispecies biofilm of Streptococcus mutans, Staphylococcus aureus,…

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Negative / Null Result ReportOpen accessMedicine

Effect of virtual reality distraction on anxiety, pain and discomfort during unsedated gastroscopy: Randomized controlled trial.

Bouman Z, De Vries F, De Ruiter M et al. · 2026 · Endoscopy international open

Background and study aims Esophagogastroduodenoscopy is a widely used medical examination. Despite the short duration of this procedure, many patients experience anxiety, pain, and discomfort. The aim of this study was to examine effects…

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Negative / Null Result ReportMedicine

Hyaluronidase activity of Indian ornamental tarantula (Poecilotheria regalis) venom is significantly reduced by commercial Latrodectus mactans and American scorpion antivenoms.

García-García M, Mosqueda J, Escobar-Cabrera JE et al. · 2025 · Toxicon : official journal of the International Society on Toxinology

A recent clinical case involving a Poecilotheria regalis bite was treated with Mexican L. mactans antivenom (Aracmyn Plus, Silanes, Mexico), resulting in the improvement of some of the symptoms. This could be attributed to cross-reactivity…

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Negative / Null Result Report

Poly-Social Risk for Hypertension Among Black and Latina Women

Belak L, James K, Auguste L et al. · 2026 · Preprint

ABSTRACT Background Hypertension is a leading modifiable cardiovascular risk factor prominently influenced by health-related social needs (HRSN). Whether detailed information on HRSN can improve identification of hypertension among…

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Negative / Null Result ReportMedicine

Assessing the Comparative Ability of Early Postoperative T4-L1PA Mismatch versus L1PA or T4PA Alone for Predicting Mechanical Complications or Spinal Reoperations: A Retrospective Analysis.

Baumann AN, Chatzis K, Son E et al. · 2026 · Spine

Study design Retrospective single-center study. Objective We aim to compare the prognostic capacity of postoperative T4-L1PA mismatch versus T4PA and L1PA alone. Summary of background data The assessment of T4-L1PA mismatch, the difference…

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Negative / Null Result ReportMedicine

Optimizing a Multimodal Large Language Model for Ultrasound-Based Thyroid Nodule Malignancy Classification: A Comparative Study of Few-Shot Learning, Prompt Engineering, and Fine-Tuning.

Li YH, Cheng YC, Chang CY et al. · 2026 · Diagnostics (Basel, Switzerland)

Objectives: Multimodal large language models (MLLMs) have shown potential for medical image classification. We evaluated four optimization strategies in two MLLMs-GPT-4o (gpt-4o-2024-08-06) and Gemini 2.5 Flash-Lite-for ultrasound-based…

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Negative / Null Result ReportMedicine

Can the Social Vulnerability Index Enhance Models Predicting Adherence to Craniofacial Speech Evaluations?

Kong BH, Dillon K, Brady CM et al. · 2026 · The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

ObjectiveTo determine whether the Centers for Disease Control and Prevention's Social Vulnerability Index (SVI) influences models of adherence to speech evaluations beyond individual demographic and clinical factors.DesignRetrospective…

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Negative / Null Result ReportMedicine

Effects of Ultra-short Offline States on Item-level Verbal Memory.

Wamsley EJ, Barron J, Livingston WH · 2026 · Journal of cognitive neuroscience

Memory is consolidated during "offline" states of reduced attention to the external stimulus environment, including sleep and resting wakefulness. While consolidation is usually studied on a timescale of hours to days, accumulating…

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Negative / Null Result ReportMedicine

Serum 25-Hydroxyvitamin D Levels did not improve with N-Acetylcysteine administration nor with abstinence in Adults Treated for Alcohol Use Disorder: A Secondary Analysis of a Randomized, Double-Blind, Placebo-Controlled Clinical Trial.

Piazza FRG, Schuch JB, Ferreira DNSDS et al. · 2025 · Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)

Objective N-acetylcysteine (NAC) is a medication known for its hepatoprotective properties and potential to reduce cravings and psychoactive substance use. Vitamin D is metabolized in the liver, and individuals with alcohol abuse often…

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Negative / Null Result ReportMedicine

Acute Effect of Thoracic Mobility Exercises on Respiratory Function and Thoracolumbar Mobility in Healthy Adults: A Pilot Crossover Trial.

Leak M, Giambini H, Cheever K et al. · 2026 · Journal of sport rehabilitation

Context Thoracic mobility is integral to respiratory function and mobility of the neck, shoulder, and spine. The efficacy of thoracic mobility exercises in enhancing respiratory function and spinal range of motion (ROM) is well documented…

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Negative / Null Result ReportMedicine

Association between arterial to end-tidal carbon dioxide gradient and prehospital hemodynamic status in patients with moderate-to-severe traumatic brain injury.

Navarro LP, Combes X, Galinski M et al. · 2026 · BMC emergency medicine

Introduction We aimed to assess the relationship between arterial partial pressure of carbon dioxide (PaCO 2 ) and end-tidal carbon dioxide (EtCO 2 ) according to three prehospital hemodynamic status and to evaluate whether…

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