20,261 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Gao Y, Liu M, Li L et al. · 2026 · The Cochrane database of systematic reviews
Background Triple-negative breast cancer (TNBC), an aggressive subtype lacking oestrogen and progesterone receptors and amplification of HER2 receptors, accounts for 12% to 17% of breast cancers. Adjuvant and neoadjuvant chemotherapy…
View details →Brock AS · 2026 · American journal of speech-language pathology
Purpose The objective of this review article is to examine and describe the literature on training speech-language pathology students on the principles of evidence-based practice (EBP). Method A scoping literature review was undertaken in…
View details →Yao S, Xu L · 2026 · Frontiers in medicine
Background Idiopathic granulomatous mastitis (IGM) is a rare chronic inflammatory breast disease characterized by a prolonged clinical course with recurrent episodes, and the optimal treatment remains controversial. Multiple systematic…
View details →Gazit N, Ben-Gal G, Eliashar R · 2026 · JMIR medical education
Background Assessment of technical aptitude, cognitive abilities, and personality characteristics is important in selecting candidates for surgical training. Currently, the selection of surgical training candidates does not systematically…
View details →Du Y, Xu Z, Wen T et al. · 2026 · Diabetes, metabolic syndrome and obesity : targets and therapy
Purpose The care of diabetic foot ulcers (DFU) continues to be a notable clinical challenge. The efficacy and safety of stem cell therapies versus conventional treatments for DFU are debated. Cross-sectional analyses of meta-analyses…
View details →Zhang Y, Wu Z · 2026 · Frontiers in public health
Background Digital technologies in oncology require patients and health workers to possess adequate electronic health literacy (eHealth literacy). Yet, the extent to which this literacy influences cancer-specific insights, ranging from…
View details →Hou YN, Gubili J, Mao JJ · 2026 · Seminars in radiation oncology
Studies show that patients with cancer use herbal products more often than the general population. Lowering the risk of disease recurrence, symptom control, and improving quality of life are often the reasons cited for such use. However, a…
View details →Kyei EF, Kyei GK, Forson MM et al. · 2026 · Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing
Aim To examine nurse practitioner opioid prescribing authority across three countries, analyzing safety outcomes, workforce distribution patterns, access equity, and service to vulnerable populations using integrated nursing policy and…
View details →Tafuri MG, Monda V, La Marra M et al. · 2026 · Nutrients
Background/Objectives: Sport participation and nutrition are increasingly recognized as key determinants of cognitive function and academic achievement in student populations. However, the biological mechanisms underpinning these…
View details →Leahy TP, Keenan C, Robertshaw E et al. · 2026 · Value in health regional issues
Objectives Growing reliance on single-arm trials (SATs) is driving increased real-world external control arm (RW-ECA) use in health technology assessment submissions. However, concerns over residual confounding and unmeasured bias often…
View details →Fuller S, Dent N, Ohly H et al. · 2026 · Preprint
Abstract Abstract Background: Infants under six months of age in low‑income countries (LICs) face high morbidity and mortality, driven by prematurity, low birthweight (LBW), malnutrition, infection, and environmental enteric dysfunction.…
View details →La Vignera S, Condorelli RA · 2026 · International journal of molecular sciences
Incretin-based therapies, particularly glucagon-like peptide-1 receptor agonists (GLP-1 RAs), have emerged as potentially promising therapeutic agents for improving ovarian function, especially in women with polycystic ovary syndrome…
View details →Luo X, Wang B, Liu H et al. · 2026 · Integrative medicine research
Background Atopic dermatitis (AD) is a common chronic inflammatory skin disorder with substantial global burden. In some regions, Chinese medicine (CM) and integrated Chinese-Western medicine (ICWM) are widely used, but the overall…
View details →Henriques JP, Weckwerth AVB, Santana ACP et al. · 2026 · Annales pharmaceutiques francaises
Objectives Diabetes mellitus and periodontal disease are highly prevalent chronic disorders linked by bidirectional inflammatory and oxidative pathways. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are emerging pharmacologic agents…
View details →Shukkoor AA, Turgeon RD, De Vera MA et al. · 2026 · BMJ open
Objectives This study aimed to investigate the association and potential causal relationship between ischaemic stroke/transient ischaemic attack (TIA) and oral anticoagulant (OAC) adherence using Bradford Hill's criteria and to determine…
View details →Mohamed D, Ramadan AA, Mabrok HB et al. · 2026 · World journal of biological chemistry
Phytosterols are plant-derived sterols structurally similar to cholesterol and present in vegetable oils, seeds, legumes, and whole grains. Their best-established health effect is lowering circulating low-density lipoprotein cholesterol,…
View details →Lande-Brenner A, Ecker UKH, Mayo R · 2026 · Scientific reports
This research demonstrates that citing scientific sources to correct disinformation can be ineffective or even counterproductive, and offers a potential remedy. Three experiments simulated a WhatsApp conversation about COVID-19 vaccine…
View details →Günther A, Bednarczyk-Cwynar B, Malinowski M · 2026 · Preprint
Background: Type 2 diabetes mellitus is a progressive cardiometabolic disease in which many patients require treatment intensification despite lifestyle intervention and evidence-based pharmacotherapy. Oleanolic acid, a pentacyclic…
View details →Edmar BA, Veen D, Klugkist I · 2026 · Preprint
Bayesian evidence synthesis (BES) provides a way of synthesising research without pooling effects, allowing for quantitative synthesise procedures when the more traditional common-effects and random-effects models cannot be used. BES can…
View details →Gallardo LM · 2026 · The American journal of clinical hypnosis
Age regression represents a foundational technique in clinical hypnosis, yet its therapeutic mechanisms, clinical applications, and evidence base remain incompletely understood and subject to ongoing controversy. This integrative critical…
View details →Tomblin Murphy G, Sampalli T, Elliott Rose A et al. · 2026 · International journal of nursing studies advances
Introduction Despite the global shortage of nurses, there is limited literature that comprehensively maps interventions to support, stabilize, and enhance the nursing workforce. Purpose This umbrella review aimed to identify structures,…
View details →Curran T, Pymm J, Gabriel J et al. · 2026 · Preprint
Abstract Cardiac fitness and rehabilitation programs offer meaningful benefits for individuals with congenital heart disease (CHD), and newer delivery models include hybrid formats combining virtual and in-person training. We hypothesized…
View details →Ordóñez-Riaño S, Jiménez-Leal W · 2026 · Acta psychologica
What motivates people to place trust in strangers-the sense that they ought to trust, or the feeling that they want to? Competing perspectives suggest that trust may be driven either by obligations or by desires. In two studies, we tested…
View details →Seymore TN, Hoffmann S, Louro P et al. · 2026 · Preprint
Fetal health is heavily dictated by the maternal environment. Inhaling airborne pollutants, like particulate matter, is associated with pregnancy complications and fetal developmental pathologies, including fetal growth restriction (FGR).…
View details →De Laet H, Nijhof AD, Wiersema JR · 2026 · Autism : the international journal of research and practice
While prevailing theories suggest social interaction difficulties are inherent to autism, the theory of the double empathy problem (DEP) proposes these difficulties arise from a mismatch between different neurotypes. The theory predicts…
View details →Agarwal N, Rochat P · 2026 · Preprint
Across two experiments, children (N = 258, ages 4–10) evaluated protagonists who either protested unfair, arbitrary rules ("good trouble") or upheld the status quo. Study 1 demonstrates that from age 5, children prefer affiliating with…
View details →Agarwal N, Rochat P · 2026 · Preprint
Across two experiments, children (N = 259, ages 4–10) evaluated protagonists who either protested unfair, arbitrary rules ("good trouble") or upheld the status quo. Study 1 demonstrates that from age 5, children prefer affiliating with…
View details →Agarwal N, Rochat P · 2026 · Preprint
Across two experiments, children (N = 259, ages 4–10) evaluated protagonists who either protested unfair, arbitrary rules ("good trouble") or upheld the status quo. Study 1 demonstrates that from age 5, children prefer affiliating with…
View details →Kiang M, Lepock JR, Mizrahi R et al. · 2026 · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
Objectives Patients at clinical high risk (CHR) for schizophrenia experience a wide range of clinical outcomes. Given this heterogeneity, long-term prognostic biomarkers are needed. The gamma-frequency EEG auditory steady-state response…
View details →Csigai P, Sparrow L, Maquet L et al. · 2026 · Scientific reports
Resting heart rate variability (HRV) is considered a marker of individuals' capacity to adapt to environmental demands, although direct empirical evidence remains limited. This study examined whether resting HRV predicts subjective and…
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