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20,261 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Hematopoietic progenitor cells (HPCs) mobilization following high-intensity interval exercise in cancer patients undergoing bone marrow transplantation: preliminary results from a randomized controlled trial.

Zarekar T, Ahmadizad S, Hajifathali A et al. · 2026 · Stem cell research & therapy

Background and objective Hematopoietic progenitor cells (HPCs) mobilization is essential for successful bone marrow transplantation but may be impaired in cancer patients due to prior treatments. High-intensity interval exercise (HIIE) has…

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Negative / Null Result ReportMedicine

Amplicon sequencing reveals impact of imidacloprid residues on diversity profile of grape fructosphere microbiota.

Deore P, Upadhyay A, Thekkumpurath AS et al. · 2026 · World journal of microbiology & biotechnology

In grape, fructosphere microbiota play an important role in nutrient cycling, pathogen suppression, berry quality, and fermentation processes. Insecticide imidacloprid (IM) is used to manage several insect pests of grape. However, the…

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Negative / Null Result ReportMedicine

Clinical Outcome of EMG-Based Pelvic Floor Biofeedback in Patients With Constipation-Impact of Prior Anorectal Manometry/Balloon Expulsion Test for Patient Selection. A Retrospective Study.

Kochhar S, Channapragada T, Shenoy V et al. · 2026 · Neurogastroenterology and motility

Introduction Pelvic floor biofeedback therapy (BFT) is the mainstay treatment for dyssynergic defecation, a condition defined by the Rome criteria. This retrospective study compares outcomes between patients referred for EMG-based BFT…

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Negative / Null Result ReportMedicine

The interplay of APOE genotype, plasma levels, and cognitive functions in middle-aged adults with a parental history of Alzheimer's disease.

Mattar YA, Refaat O, El-Makawi S et al. · 2026 · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry

Background Family history and APOE ε4 carriage represent the strongest non-modifiable Alzheimer's disease (AD) risk factors after advancing age. Early identification of cognitive markers in individuals at risk is essential for effective…

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Negative / Null Result ReportMedicine

Axial Force Transmission Through Orthosis Straps in a Neonatal Hip Flexion-Abduction Orthosis: An Exploratory In Vivo Study in Infants with Developmental Dysplasia of the Hip.

Schwanitz von Keitz P, Liebau KH, Mittelmeier W et al. · 2026 · Children (Basel, Switzerland)

Background: Developmental dysplasia of the hip (DDH) is the most common congenital musculoskeletal disorder in newborns. Flexion-abduction orthoses are widely used in early treatment; however, in vivo data on their biomechanical load…

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Negative / Null Result Report

Longitudinal Interaction Between Frailty and Postoperative Symptom Burden in Elderly Patients Undergoing Colorectal Cancer Surgery: A Random Intercept Cross-Lagged Panel Model Study

Li P, Ge L, Liu Y et al. · 2026 · Preprint

Background: /Objectives: Frailty and postoperative symptom burden are prevalent in older adults undergoing colorectal cancer (CRC) surgery, but their temporal, within-person interplay remains unclear. We aimed to investigate this…

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Negative / Null Result ReportMedicine

A randomized controlled trial to evaluate the efficacy and safety of a double-walled incubator compared to a radiant warmer in the care of extremely low-birth-weight infants.

Kabra NS, Umate SS, Halder P et al. · 2026 · Journal of tropical pediatrics

This study compared the safety and efficacy of double-walled incubators versus radiant warmers in extremely low-birth weight (ELBW: birth weight < 1000 g) preterm infants, hypothesizing that incubator care would reduce the time to regain…

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Negative / Null Result ReportMedicine

Macromolecular crowding and ionic strength diminish the energetic severity of the Arrhenius break point of thermolysin: Implications for biological significance.

Miller JJ, Duggal M, Bahnson BJ · 2026 · Protein science : a publication of the Protein Society

A growing number of enzymes demonstrate deviations from typical linear kinetic temperature dependencies as modeled by the Arrhenius and Eyring equations. These deviations may manifest as biphasic temperature dependencies consisting of two…

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Negative / Null Result ReportMedicine

Perioperative Outcomes of Robot-Assisted Partial Nephrectomy Using Hinotori Compared With da Vinci Xi: A Propensity Score-matched Analysis.

Kanehira M, Nozaki Y, Ogasawara K et al. · 2026 · The international journal of medical robotics + computer assisted surgery : MRCAS

Introduction Robot-assisted partial nephrectomy (RAPN) using the da Vinci Surgical System (DVSS) is broadly performed globally. In Japan, the Hinotori Surgical Robot System (HSRS) has recently been developed. However, few studies have…

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Negative / Null Result ReportMedicine

Achilles tendon rupture does not significantly reduce career longevity in professional soccer players compared with matched controls.

Khan HA, Khan A, Rosenberg A et al. · 2026 · Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA

Purpose To compare the career longevity of professional soccer players after achilles tendon rupture (ATR) with that of an uninjured matched control cohort. Methods A retrospective analysis of ATR cases in professional male athletes from…

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Negative / Null Result ReportMedicine

Does a Brochure Reduce Dental Anxiety in Patients Undergoing Third Molar Extraction? A Randomized Clinical Trial.

Schemel-Suarez M, Egido-Moreno S, Martínez-Lizan I et al. · 2026 · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons

Background Dental anxiety frequently compromises patient cooperation and outcomes during third molar (3M) extraction prompting the use of nonpharmacological strategies such as detailed written information. Evidence on reducing preoperative…

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Negative / Null Result ReportMedicine

Effect of additive manufacturing technology and print orientation on the accuracy of static guided implant surgery: An in vitro study.

Amini S, Alshammari M, Abdulhameed N et al. · 2026 · Journal of prosthodontics : official journal of the American College of Prosthodontists

Purpose The aim of this in vitro study was to investigate the effect of print orientation and printing technology on the accuracy of static computer-aided implant surgery (s-CAIS). Materials and methods A cone beam computed tomography…

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Negative / Null Result ReportMedicine

Exploring a Single Music Therapy Session to Reduce 22q11.2 Deletion Syndrome Child and Adolescent's Outpatient Clinic-Related Anxiety.

Broughton MC, Bunzli E, Pagel S et al. · 2026 · Journal of paediatrics and child health

Aim This study explored whether a single music therapy session could reduce 22q11.2 deletion syndrome (DS) children and adolescents' clinic-related anxiety when visiting the hospital outpatient clinic for health appointments. Methods The…

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Negative / Null Result ReportMedicine

Mediating effects of depression, stigma, and self-efficacy on self-management improvement in an evidence-based epilepsy self-management program.

Armah L, Tan L, Branning R et al. · 2026 · Epilepsy & behavior : E&B

Aims To evaluate whether improvements in depressive symptoms, epilepsy self-efficacy, and perceived stigma mediate the association between the SMART intervention and epilepsy self-management. Methods 160 people with epilepsy were enrolled…

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Negative / Null Result ReportMedicine

Relationship Between Mental Health and Protective Health Behaviors in Adolescents: A Secondary Data Analysis.

Mahat G, Zha P · 2026 · Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners

Evidence highlights rising mental health concerns among youth. This study investigated the relationship between protective behaviors, including physical activity, regular breakfast, sleep, and parental monitoring, and adolescent mental…

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Negative / Null Result ReportMedicine

Impact of oral glucocorticoids on the effectiveness of romosozumab: the multicenter OASIS cohort study.

Yukishima T, Kobayakawa T, Hirano Y et al. · 2026 · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

This multicenter retrospective cohort compared romosozumab outcomes between oral glucocorticoid users and non-users. Bone turnover marker responses and lumbar spine bone mineral density gains were similar, whereas total hip bone mineral…

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Negative / Null Result ReportMedicine

Non-alcoholic beverage provision reduces alcohol consumption and improves health-related outcomes, with no effect on presenteeism: a randomized controlled trial.

Dobashi S, Hotoge S, Kikuchi A et al. · 2026 · Scientific reports

Excessive alcohol consumption contributes to mortality and productivity losses, yet evidence for workplace-based substitution interventions remains limited. This randomized controlled trial examined whether providing non-alcoholic…

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Negative / Null Result ReportMedicine

Reliability of Noninvasive Blood Pressure Monitoring During Atrial Fibrillation Ablation Under General Anesthesia.

Schwartz J, Al-Sadawi M, Mattimore D et al. · 2026 · Journal of cardiothoracic and vascular anesthesia

Objectives To evaluate the accuracy and reliability of noninvasive blood pressure (NIBP) monitoring compared to invasive blood pressure (IBP) measurements during atrial fibrillation (AF) ablation under general anesthesia, and to determine…

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