Negative / Null Result ReportMedicine
Athan E, Greenberg RN, Baker DA et al. · 2026 · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Background A vaccine that prevents Staphylococcus aureus skin and soft tissue infections (SA-SSTIs) would have a major impact on public health. Methods A two-part randomized study began with a phase 1, first-in-human, dose-escalation that…
View details →Negative / Null Result ReportMedicine
Carvajal-Encina F, Carvajal Rojas L · 2025 · Andes pediatrica : revista Chilena de pediatria
Prematurity is a challenge due to its high morbidity and mortality. The Explicit Health Guarantees (GES) for Premature Birth Prevention, implemented in 2005, have not been evaluated. Objective To evaluate the impact of the GES on perinatal…
View details →Negative / Null Result ReportMedicine
Chung J, Park S, Park SJ et al. · 2026 · The American journal of medicine
Objective This study aimed to evaluate the conflicting effects of weight change and smoking cessation on fracture risk in male patients with newly diagnosed type 2 diabetes mellitus (T2DM). Methods Using the National Health Insurance…
View details →Negative / Null Result ReportMedicine
Paskeviciene E, Skemiene K, Pampuscenko K et al. · 2025 · Journal of pharmacological sciences
Imeglimin, a novel oral antidiabetic drug, has been suggested to affect mitochondrial functions in some types of cells and tissues, however, it has never been investigated whether aging has an impact on its pharmacological effects in the…
View details →Negative / Null Result ReportMedicine
Streit A, Hoffmann M, Blesl A et al. · 2025 · Quality management in health care
Background Effective discharge planning is an important factor of hospital care and should follow a comprehensive assessment of patients at risk for adverse events during discharge. The study's aim was to analyze whether the use of the…
View details →Negative / Null Result ReportOpen accessMedicine
Büyükbezirci G, Demiralp N, Keles S et al. · 2026 · Journal of pain research
Purpose Postherpetic neuralgia (PHN) is one of the most debilitating complications of herpes zoster and represents a major cause of chronic neuropathic pain. Increasing evidence suggests that immune dysregulation plays a critical role in…
View details →Negative / Null Result ReportMedicine
Shidara S, Ito S, Desai K et al. · 2026 · Bone
Skeletal stem/progenitor cells (SSPCs) play a fundamental role in maintaining skeletal homeostasis throughout life. Leptin receptor (Lepr)-positive cells were initially identified as SSPCs in the long bone marrow and later in the…
View details →Negative / Null Result ReportOpen accessMedicine
Kim HJ, Kim N, Kim J et al. · 2025 · Scientific reports
Robot-assisted laparoscopic prostatectomy (RALP) is associated with hemodynamic shifts; patients on angiotensin receptor blockers (ARBs) are especially susceptible to intraoperative hypotension. We investigated whether induction with…
View details →Negative / Null Result ReportMedicine
Berthoud V, Nguyen M, Vinay J et al. · 2026 · Anaesthesia, critical care & pain medicine
Introduction In thoracic surgery, all respiratory muscles have a significant increase in workload, and recruitment of these muscles may be important, especially in the presence of diaphragmatic dysfunction. Evaluating diaphragmatic and…
View details →Negative / Null Result ReportMedicine
Bircher B, Aebischer P, Wimmer W et al. · 2026 · American journal of otolaryngology
Objective To evaluate the clinical implementation of preoperative, anatomy-tailored planning for electrode selection in cochlear implantation, quantify planning accuracy under routine conditions, and identify factors associated with…
View details →Negative / Null Result ReportMedicine
Hao X, Zhang Z, Cai C et al. · 2026 · International journal of surgery (London, England)
Background Dexmedetomidine was widely used in anesthesia management during cardiac surgery. The purpose was to evaluate the safety and efficacy of intraoperative dexmedetomidine in the treatment of postoperative depression in adult…
View details →Negative / Null Result ReportMedicine
Wittberg DM, Admassu F, Aragie S et al. · 2026 · Tropical medicine & international health : TM & IH
Objectives Few randomised trials have been done to assess the impact of hygiene interventions on trachoma even though hygiene improvements feature prominently in the strategy for global elimination of trachoma. This study's aim was to…
View details →Negative / Null Result ReportMedicine
Liu C, Deng G, Wang Y et al. · 2026 · Stroke and vascular neurology
Background Transradial access has become an increasingly preferred approach for cerebral angiography. However, embolic events, often clinically silent, remain a frequent concern. Despite routine use, the efficacy and safety of heparin…
View details →Negative / Null Result ReportOpen accessMedicine
Jiang C, Zhao Z, Yang Z et al. · 2026 · Circulation
Background Observational studies have suggested that SGLT2 (sodium-glucose cotransporter 2) inhibitors are associated with a lower risk of atrial fibrillation (AF) recurrence after catheter ablation in patients with AF with concomitant…
View details →Negative / Null Result ReportMedicine
Krzyżaniak M, Warmiński K, Olba-Zięty E et al. · 2025 · Industrial Crops & Products
Camelina sativa (L. Crantz) is an annual oilseed crop cultivated for industrial and food purposes. To expand camelina's cultivation area, improve yields, and reduce weed pressure, the crop can be grown in intercropping system. The aim of…
View details →Negative / Null Result ReportMedicine
Perez-Valero I, Corona Mata D, Crussells Canales MJ et al. · 2026 · International journal of antimicrobial agents
Objective To evaluate if switching from dolutegravir/lamivudine (DTG/3TC) to bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) improves neuropsychiatric tolerability in suppressed adults with stable neuropsychiatric…
View details →Negative / Null Result ReportMedicine
Zhang F, Zhong Y, Li Q et al. · 2025 · High altitude medicine & biology
Zhang, Fengying, Yang Zhong, Qiuyue Li, Doudou Hao, Zhiyou Shi, Suying Zhu, Qian Zhang, and Yunhong Wu. Does Hydrogen-Rich Water Reduce Oxidative Stress in Patients with Chronic Mountain Sickness? A Randomized, Blinded, Controlled Trial.…
View details →Negative / Null Result ReportMedicine
Crawford AM, Striano BM, Schoenfeld AJ et al. · 2026 · Spine
Study design Retrospective multicenter cohort study. Objective To compare the safety and efficacy of venous thromboembolism prophylaxis (VTE) strategies between two high-volume spine centers with distinct protocols. Summary of background…
View details →Negative / Null Result ReportMedicine
Kinsella A, Gilligan P · 2025 · Irish medical journal
Aim Admission rate is a key performance indicator for Emergency Departments (EDs). Senior hospital management advised that, if discharge by on-call teams was possible within 24 hours, a patient should be termed 'ambulatory' and remain in…
View details →Negative / Null Result ReportMedicine
Alves LL, Pinheiro Rosa DC, Freire ML et al. · 2025 · The Journal of antimicrobial chemotherapy
Objective This study aimed at evaluating the combination of a topical hydrophilic gel of paromomycin (PA) with intralesion meglumine antimoniate (Glu IL) or systemic administration of liposomal amphotericin B (AmphLipo) for the treatment…
View details →Negative / Null Result ReportOpen accessMedicine
Warrier T, Martínez-Hoyos M, Porras De Francisco E et al. · 2026 · ACS infectious diseases
A bromoindazole was reported with the ability to rapidly and extensively kill Mycobacterium tuberculosis (Mtb) in vitro, but only in the presence of sublethal levels of reactive nitrogen species (RNS) (Warrier et al., ACS Infectious…
View details →Negative / Null Result ReportMedicine
Sher DJ, Avkshtol V, Lin MH et al. · 2025 · Journal of the National Cancer Institute
Background The utility of adaptive radiotherapy (ART) for head and neck squamous cell carcinoma (HNSCC) remains poorly defined. Daily ART (DART) promises both anatomic adaptation and planning target volume (PTV) reduction. In this…
View details →Negative / Null Result ReportMedicine
Furman CR, Worth IA, Zhang JD et al. · 2025 · Behavioral medicine (Washington, D.C.)
Eating and exercise habits established in adolescence are associated with immediate and long-term health outcomes. These habits may be influenced by adolescents' socioeconomic status (SES), such that low SES households often experience…
View details →Negative / Null Result ReportOpen accessMedicine
Hay AD, Abbs S, Ridd M et al. · 2026 · JAMA internal medicine
Importance Most antibiotic prescribing takes place in primary care, driving antimicrobial resistance, a top-10 threat to global public health. There is considerable international interest in whether rapid multiplex microbiological…
View details →Negative / Null Result ReportMedicine
Zhang IY, Flum DR, Khandelwal S et al. · 2025 · Annals of surgery
Objective We aimed to evaluate the impact of an electronic health record (EHR)-based default "nudge" intervention on opioid prescribing after common surgical operations. Background Given ongoing national challenges in opioid use and…
View details →Negative / Null Result Report
Le Sage V, Vu MN, Maltepes MA et al. · 2025 · Preprint
In China, low pathogenic avian influenza (LPAI) H3N8 virus is widespread among chickens and has recently caused three zoonotic infections, with the last one in 2023 being fatal. Here we evaluated the relative pandemic risk of this 2023…
View details →Negative / Null Result ReportMedicine
Xu J, Chen Y, Gong C et al. · 2025 · Journal of infection in developing countries
Introduction Tuberculous empyema, a severe complication of pulmonary tuberculosis, often requires surgical intervention in stage III to remove fibrotic tissue and restore lung function. Methodology This retrospective study enrolled 224…
View details →Negative / Null Result ReportMedicine
Baltruskeviciute L, Moccetti F, Wolfrum M et al. · 2026 · The American journal of cardiology
Cerebrovascular accidents (CVA) after transcatheter aortic valve implantation (TAVI) remain a major concern. However, the impact of aortic arch morphology has not been investigated in this context. To address this gap, consecutive patients…
View details →Negative / Null Result ReportMedicine
Madden KM, Feldman B, Meneilly GS · 2025 · Canadian journal on aging = La revue canadienne du vieillissement
Postprandial hypotension (PPH) is defined as a postprandial decline in systolic blood pressure (SBP) of 20 mm of Hg. Some have recommended the use of acarbose (an alpha-glucosidase inhibitor) as a potential therapy for PPH based…
View details →Negative / Null Result ReportOpen accessMedicine
Martínez-Lentisco MDM, Carreño-Segura S, León-Morillas F et al. · 2026 · Clinical pediatrics
This quasi-experimental study assessed the impact of a postpartum educational programme on health care utilization and maternal stress in mothers of infants with colic. A total of 84 mothers took part in 2 individual sessions, 15 days…
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