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Browse the failure-mode index

19,893 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Early hearing deprivation by silicon earplugs does not alter electrophysiological development of mouse dorsal cochlear nucleus fusiform neurons.

Sasaki AE, Benites NM, Rodrigues B et al. · 2025 · Hearing research

Rodent auditory brainstem neurons undergo substantial electrophysiological maturation during the postnatal period, spanning both pre- and post-hearing phases. These developmental adaptations support high-frequency, temporally precise…

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Negative / Null Result ReportOpen accessMedicine

The effect of sex on the isolated and combined α- and β-adrenergic control of blood flow during handgrip in adults at high altitude: An exploratory study.

Maier LE, Vanden Berg ER, Simpson L et al. · 2026 · Physiological reports

This study examined how sex influences blood flow during exercise at altitude and relative contributions of adrenergic mechanisms. Thirteen participants (8 M/5F) were tested at low and high altitude (days 3-11). Participants performed…

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Negative / Null Result ReportOpen accessMedicine

Bioceramic arm garment does not increase diameter of brachial artery and blood flow-Compliance and biceps microcirculation in male recreational sports practitioners at rest: A single blinded randomized cross-over study.

Chamoux M, Rakobowchuk M, Gaston AF et al. · 2025 · Journal of sport and health science

Background Interest in clothing that reflects far infrared (FIR) radiation naturally emitted by the body during and after exercise has increased based on the assumption that this can increase arterial and venous blood flow. Indeed, in…

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Negative / Null Result ReportMedicine

Trace element and δ<sup>13</sup>C values of the banana prawn Penaeus merguiensis reveal the importance of catchment-derived resources across both estuarine and nearshore habitats.

Munroe S, O'Mara K, Kenyon R et al. · 2025 · Marine environmental research

Wet season freshwater flows deliver catchment nutrients (terrestrial and freshwater) to tropical estuaries that stimulate productivity and support consumers. However, the impact of flows on species in the adjacent nearshore is unclear. We…

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Negative / Null Result ReportMedicine

Combined ketamine and psychotherapy provide no additional benefit beyond ketamine alone in treating depression or PTSD: Evidence from a help-seeking sample.

Moore TM, Walker K, Tung E et al. · 2025 · Journal of affective disorders

Depression and PTSD are prevalent psychiatric conditions that often co-occur and significantly impact quality of life. Ketamine has emerged as a promising rapid-acting treatment for both conditions, while traditional treatments like…

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Negative / Null Result ReportOpen accessMedicine

The Effect of Flow-Controlled Ventilation on Mechanical Power in Laparoscopic Surgeries: A Comparative Analysis with Pressure Controlled Volume Guaranteed and Volume Controlled Ventilation.

Sencan A, Dundar N, Gunel B et al. · 2025 · Medeniyet medical journal

Objective To compare mechanical power (MP) levels among flow-controlled ventilation (FCV), volume-controlled ventilation (VCV), and pressure-controlled volume-guaranteed ventilation (PCV-VG) during laparoscopic surgery and to test the…

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Negative / Null Result ReportMedicine

Longitudinal Associations Between Cannabis Use during Pregnancy and Child Cognitive, Motor, and Language Development at 2 Years Old.

Pleau J, Tanguay N, Courtemanche Y et al. · 2025 · Maternal and child health journal

Objectives The objectives of this study are to describe cannabis use during pregnancy, identify associated factors, examine the associations between prenatal cannabis use and the cognitive, motor and language development of 2-year-old…

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Negative / Null Result Report

Short Naps Improve Subsequent Learning in a High School Setting

Vidal V, Pretel MR, Capurro L et al. · 2024 · Preprint

Abstract The application of neuroscience findings in educational settings offers promising opportunities to enhance academic performance. Adolescents, particularly affected by delayed sleep patterns due to early school start times, often…

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Negative / Null Result Report

Range-wide assessment of the Tasmanian devil gut microbiome

Molloy M, McLennan E, Fox S et al. · 2024 · Preprint

The gut microbiome is an important component of host health and function and is influenced by internal and external factors such as host phylogeny, age, diet, and environment. Monitoring the gut microbiome has become an increasingly…

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Negative / Null Result ReportOpen accessMedicine

Determinants of changes in self-esteem after remission of first-episode psychosis: A study of associated cross-sectional and longitudinal factors.

Hidding M, van der Stouwe E, Rosema BS et al. · 2025 · Psychological medicine

Background Low self-esteem is an important and potentially modifiable risk factor for the development and outcome of psychotic disorders. The factors involved in low self-esteem in psychotic disorders are not yet fully understood. The…

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