Negative / Null Result ReportOpen accessBotany
YANG Xingwang, WANG Zhiqiang, DUAN Chenlei et al. · 2025 · Guoshu xuebao
[Objective] The cultivation practices for Jinhuangjin peach in Yiyuan County are characterized by family-based operations, with most planting areas being less than 5 acres. The level of mechanization is relatively low, and the average age of fruit farmers exceeds 55 years old. Foliar fertilizer technology is readily adopted in local orchard management, demonstrating high acceptance among fruit farmers. The experiment was carried out to investigate the effects of two foliar fertilizesr on fruit quality and volatile flavor compounds in Jinhuangjin peach in Yiyuan region, so as to provide theoret
View details →Negative / Null Result ReportOpen accessPhysiology
Yu. A. Dyleva, O. V. Gruzdeva, E. V. Belik et al. · 2023 · Ожирение и метаболизм
BACKGROUND: The information available to date on the effect of metformin on the transcriptome and secretory capacity of adipocytes in human adipose tissue (AT) is scarce and contradictory. The study analyzed whether metformin in vitro modulates gene expression and secretion of adiponectin and leptin in the AT of subcutaneous (SAT), epicardial (EAT) and perivascular (PVAT) localization of patients with ischemic artery disease (IHD).AIM: To assess the effect of metformin at various concentrations (1 and 10 mmol / L) on the level of expression of adiponectin and leptin genes and their content in
View details →Negative / Null Result ReportOpen accessMedicine
Viktoriia V. Yevsieieva, Volodimyr I. Cherniy, Kateryna V. Kharchenko et al. · 2023 · Клінічна та профілактична медицина
Introduction. One of the main factors affecting postoperative outcomes in patients with advanced ovarian cancer is the cardiopulmonary status. Several studies have reported that preoperative multifactorial rehabilitation and physical fitness can lead to reduced postoperative morbidity, mortality, shorter length of stay, and improved quality of life in cancer patients. The issue of adaptability to physical activity of overweight and obese patients who undergoing debulking surgery is insufficiently studied. The study of compensatory changes that occur in physically inactive obese patients remain
View details →Negative / Null Result ReportOpen accessPublic aspects of medicine
Chabot Isabelle, Potvin Louise, Moisan Jocelyne et al. · 2006 · BMC Health Services Research
Abstract Background Drug utilization review (DUR) programs are being conducted in Canadian hospitals with the aim of improving the appropriateness of prescriptions. However, there is little evidence of their effectiveness. The objective of this study was to assess the impact of both a retrospective and a concurrent DUR programs on the quality of in-hospital prescribing. Methods We conducted an interrupted time series quasi-experimental study. Using explicit criteria for quality of prescribing, the natural history of cisapride prescription was established retrospectively in three university-aff
View details →Negative / Null Result ReportOpen accessOrthopedic surgery
A. Sukru Solak, Erbil Aydin, Ersan Boysan et al. · 2021 · Acta Orthopaedica et Traumatologica Turcica
Abstract We evaluated pre and postoperative pulmonary functions of 48 patients who underwent posterior fusion for the adolescent idiopathic scoliosis. The mean age at the time of surgery was 13±1.5 years. Average follow-up time was 2.7 years. The predicted pulmonary volumes of the patients were used to eliminate any effect of the difference in age. In this study we didn t found any relation between the pre and postoperative frontal and sagittal plane Cobb angles and pulmonary volumes. Only for the residual volume there was a significant increase but the increase for the vital capacity and forc
View details →Negative / Null Result ReportOpen accessMedicine
Björkman AS, Malusek A, Persson A et al. · 2026 · European radiology experimental
Objective The aim was to compare the image quality of photon-counting detector CT (PCD-CT) and energy-integrating detector CT (EID-CT) in patients with tibial plateau fractures treated with metallic osteosynthesis material, and to identify…
View details →Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Jiaying Rong, Yanyong Wang, Na Liu et al. · 2024 · Brain Research Bulletin
Background: Chronic stress can induce the cognitive impairment, and even promote the occurrence and development of Alzheimer's disease (AD). Evidence has suggested that chronic stress impacts on glucose metabolism, and both of these have been implicated in AD. Here we focused on the effect of insulin resistance in glucose metabolism, and further evaluated the changes in cognition and pathology. Methods: Male 9-month-old wild-type and APP/PS1 mice were randomly divided into 4 groups. Mice in the chronic unpredictable mild stress (CUMS) groups were exposed for 4 weeks. Homeostatic Model Assessme
View details →Negative / Null Result ReportOpen accessEcology
Xiangzhou Zheng, Aiai Xu, Yan Lin et al. · 2024 · Global Ecology and Conservation
Subtropical Moso bamboo (Phyllostachys edulis) forests have become hot spots for nitrogen (N) deposition in China. However, the effect of long-term N deposition on the structure of soil microbial communities in different horizons of these forests remains unclear. To investigate the influence of extended N deposition on soil bacteria and fungi, a simulated N deposition field study was conducted in Fujian Province with four N deposition levels (0, 20, 40 and 80 kg N hm−2 a−1). The absolute abundances, diversity, community structure, and potential functions of soil bacteria and fungi were investi
View details →Negative / Null Result ReportOpen accessZoology
Biljana Ječmenica, Louie Taylor, Jelena Kralj et al. · 2026 · Avian Research
The Yellow-legged Gull (Larus michahellis) is a widespread and opportunistic central-place forager during the breeding season, yet its spatial behavior and habitat use in Adriatic Sea remain poorly understood. Our aim was to investigate their foraging ranges, movement patterns, and habitat selection during the breeding season. In this study, we tracked 45 adult gulls from 9 breeding colonies distributed along the Adriatic coast using high-resolution GPS devices. Most individuals foraged relatively close to their breeding sites, typically within 20–50 km. However, some gulls demonstrated the ca
View details →Negative / Null Result ReportOpen accessMedicine
P.F. Wong, M.P.L. Cheung, O WS et al. · 2014 · Asian Pacific Journal of Reproduction
Objective: To study the effect of inter medin(IMD) on smooth muscle of rat seminal vesicles including the specific receptors and the signal pathways involved. Methods: The contraction of the seminal vesicle in response to norepinephrine (NE) and ADM2/IMD was studied by the organ bath method. The effects of antagonists for calcitonin gene related peptide (CGRP), adrenomedullin (ADM) and IMD receptors, and inhibitors of nitric oxide synthase, [L-NG-Nitroarginine Methyl Ester, L-NAME) and cAMP-dependent protein kinase (PKA), KT5720] were also investigated. The first overshoot, amplitude, frequenc
View details →Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Nieves Martínez-Lago, Ana Fernández-Montes, Marta Covela et al. · 2021 · BMC Cancer
Abstract Background Outcomes are poorer in metastatic colorectal cancer (mCRC) patients with BRAF V600E mutations than those without it, but the effect of these mutations on treatment response is unclear. This real-world study assessed the effects of antiangiogenic-based treatment and systemic inflammatory factors on outcomes in patients with BRAF V600-mutated mCRC. Methods This real-world, multicenter, retrospective, observational study included patients with BRAF V600-mutated mCRC treated in eight hospitals in Spain. The primary endpoints were overall survival (OS) and progression-free survi
View details →Negative / Null Result ReportOpen accessDiseases of the endocrine glands. Clinical endocrinology
Hania Szajewska, Agnieszka Szypowska, Lidia Groele et al. · 2021 · BMJ Open Diabetes Research & Care
Introduction The gut microbiota may be relevant in the development of type 1 diabetes (T1D). We examined the effects of Lactobacillus rhamnosus GG and Bifidobacterium lactis Bb12 on beta-cell function in children with newly diagnosed T1D.Research design and methods Children aged 8–17 years with newly (within 60 days) diagnosed T1D were enrolled in a double-blind, randomised controlled trial in which they received L. rhamnosus GG and B. lactis Bb12 at a dose of 109 colony-forming units or placebo, orally, once daily, for 6 months. The follow-up was for 12 months. The primary outcome measure was
View details →Negative / Null Result ReportMedicine
Dang M, Bishop Z, Schick KD et al. · 2026 · Child abuse & neglect
Background In child maltreatment investigations, forensic interviewers must elicit accurate narratives while prioritizing children's wellbeing in a safe environment that minimizes distress. While note-taking may help reduce suggestive…
View details →Negative / Null Result ReportOpen accessEnvironmental sciences
Sumardiono Siswo, Meganingtyas Wahyudita, Cahyono Heri · 2025 · E3S Web of Conferences
Artificial rice is one of the food diversification efforts that can be made from non-rice foodstuffs to reduce dependence on rice. In this study, artificial rice was made from a composite flour as raw material composed of modified cassava flour (mocaf) (Manihot esculenta), sago flour (Metroxylon sago Rottb), yellow pumpkin flour (Cucurbita moschata L.), and soybean flour (Glycine max) in different formula ratios. Artificial rice was produced using the extrusion method at temperatures of 70, 80, and 90°C. In this study, the artificial rice was analyzed for chemical and physical properties (wate
View details →Negative / Null Result ReportOpen accessMedicine
Kristiina Aalto, Hannu Kautiainen, Anders Fasth et al. · 2025 · RMD Open
Introduction The age at the onset of juvenile idiopathic arthritis (JIA) can influence the trajectory of the disease. We aimed to clarify how age at the visit 6 months after the onset as a continuous variable affects long-term remission of JIA.Methods This study investigated 358 patients from the Nordic JIA cohort study. Age at diagnosis was analysed continuously. Three age groups were studied: under 3 years, 3–5 years and over 6 years of age. JIA was categorised as oligoarthritis, seronegative polyarthritis and others (enthesitis-related, psoriatic and undifferentiated arthritis). Clinical da
View details →Negative / Null Result ReportOpen accessMedicine (General)
Seyed Mohammad Mousavi, Alireza Milajerdi, Memhdi Sshayanfar et al. · 2019 · Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum
Background and Objectives: Limited data are available on the relationship between dietary factors and risk of glioma. The current study was conducted to investigate the association between dietary acid load (DAL) and risk of glioma in Iranian adults. Methods: This case-control study was carried out on 128 patients with glioma and 256 healthy subjects (Matched for age and sex) in Tehran, Iran. A validated detailed food frequency questionnaire (FFQ) was used to assess dietary intakes of the participants. DAL was estimated using the protein to potassium ratio (Pro/K) and Glioma was diagnosed base
View details →Negative / Null Result ReportOpen accessAgriculture
Mariyah Mariyah, Rita Mariati, Eko Harri Yulianto Arifin · 2025 · Ziraa'ah: Majalah Ilmiah Pertanian
Analysis of Paddy Farming Performance in Tenggarong Seberang with Stochastic Frontier Analysis Approach. Providing food, especially rice, requires efforts to increase the productivity of rice farming. Good farm management can be measured through technical efficiency. Tenggarong Seberang district is one of the centers of rice production in Kutai Kartanegara Regency and is also a rice supply area to other regions in East Kalimantan. The research aims to identify production factors that affect production, to analyze the technical efficiency and inefficiency factors in rice farming. The research w
View details →Negative / Null Result ReportOpen accessOther systems of medicine
Shan-bo Ma, Lun Liu, Xiang Li et al. · 2023 · BMC Complementary Medicine and Therapies
Abstract Background The dried bark of Ailanthus altissima (Mill.) Swingle is widely used in traditional Chinese medicine for the treatment of ulcerative colitis. The objective of this study was to explore the therapeutic basis of the dried bark of Ailanthus altissima (Mill.) Swingle for the treatment of ulcerative colitis based on Virtual Screening–Molecular Docking–Activity Evaluation technology. Methods By searching the Traditional Chinese Medicine Systems Pharmacology TCMSP Database and Analysis Platform, 89 compounds were obtained from the chemical components of the dried bark of Ailanthus
View details →Negative / Null Result ReportOpen accessMedicine
Ting-Ting Xu, Rui Cao, Yan-Ling Dong et al. · 2022 · PLoS ONE
This study aimed to analyze the factors of rapid attenuation of graft endothelium in the early stage after penetrating keratoplasty (PKP), with a view to guiding patients with PKP to better long-term outcomes. This study included 226 patients who underwent PKP with follow-up time >1 year at the Qingdao Eye Hospital of Shandong First Medical University from January 2018 to June 2020. Medical records were retrospectively studied, and donor factors, patient factors, and surgical factors were comparatively analyzed to clarify those affecting the rapid decay of graft endothelium after PKP. The medi
View details →Negative / Null Result ReportOpen accessToxicology. Poisons
Mohamed Bedair M. Ahmed, Gomaa N. Abdel-Rahman, Salah H. Salem et al. · 2020 · Toxicology Reports
The current study was conducted to determine sulfonamides (SAs) and tetracyclines (TCs) residuals in farmed Nile Tilapia fish (Orechromis niloticus) using the solid phase extraction (SPE) technique and high performance liquid chromatography with diode array detection (HPLC-DAD). As well, to assess the potential health risk due to the consumption of contaminated fish following its household thermal processing. Tilapia samples were collected from four governorates in Egypt; El-Fayoum, Giza, Cairo, and Alexandria. The results showed that 56.3 % (27 out of 48 samples) of fish samples were free of
View details →Negative / Null Result ReportOpen accessAnimal culture
N. Piaskowska, T. Daszkiewicz, D. Kubiak et al. · 2016 · Asian-Australasian Journal of Animal Sciences
This study evaluated the effect of vacuum and modified atmosphere (40% CO2+60% N2, MA) packaging on the chemical composition, physicochemical properties and sensory attributes of chill-stored meat from 10 fallow deer (Dama dama) bucks at 17 to 18 months of age. The animals were hunter-harvested in the forests of north-eastern Poland. During carcass dressing (48 to 54 h post mortem), both musculus longissimus muscles were cut out. Each muscle was divided into seven sections which were allocated to three groups: 0, A, and B. Samples 0 were immediately subjected to laboratory analyses. Samples A
View details →Negative / Null Result ReportOpen accessVeterinary medicine
Hesham Azouz · 2019 · Egyptian Poultry Science
The objective of this study was to investigate the effect of dietary supplementation with turmeric (TU), hot pepper (HP), or a combination of them as a powder on productive performance and functional properties of table eggs local strain (Sinai strain) hens at late production phase . A total number of 105 Sinai hens, 59-wks-old were weighed individually and randomly distributed equally into seven experimental treatments of three replicates each. The experimental design consists of the following groups; the first group was fed the basal diet without studied supplements and served as a control.
View details →Negative / Null Result ReportOpen accessFood processing and manufacture
Fariba Hadidi, Ali Ganjloo, Mohammad Hadi Fakoor · 2023 · مجله پژوهشهای علوم و صنایع غذایی ایران
Introduction The demand for non-dairy and reduced-calorie products has increased substantially for several reasons. Almond (Prunus dulcis) milk is highly appreciated by lactose-intolerant, hypertensive people and celiac patients whom are not able to consume animal's milk. Thus, the development of various non-dairy products is essential. Desserts are the most common and popular product containing high amount of fat and sucrose. The consumption of sucrose is restricted for diabetic people due to its high glycemic index. Stevia as a low-calorie sweetener is one of the sucrose substitutes in food
View details →Negative / Null Result ReportOpen accessFinance
ebrahim abbasi, saeed hoshmand · 2016 · راهبرد مدیریت مالی
The purpose of this study is to investigate the effect of capital gain plans on return cumulative and buy (sell) pressure on the days around assembly. In this study, capital gain means shareholders benefit from receivables financing (stock rights) and conversion of retained earnings into new shares (profit share) for fixed investment and development. According to the price pressure hypothesis, issuance of new shares leads to an increase in supply and accordingly, the stock returns and trading volume are affected. 100 companies which over the years from 2003 to 2014 have increased their capital
View details →Negative / Null Result ReportOpen accessDiseases of the musculoskeletal system
Zhenhan Deng, Xueqin Gao, Hajime Utsunomiya et al. · 2022 · Bone Reports
Background and aims: Previous work has shown that oral losartan can enhance microfracture-mediated cartilage repair in a rabbit osteochondral defect injury model. In this study, we aimed to determine whether oral losartan would have a detrimental effect on articular cartilage and bone homeostasis in the uninjured sides. Methods: New Zealand rabbits were divided into 4 groups including normal uninjured (Normal), contralateral uninjured side of osteochondral defect (Defect), osteochondral defect plus microfracture (Microfracture) and osteochondral defect plus microfracture and losartan oral admi
View details →Negative / Null Result ReportOpen accessSocial Sciences
Tety Anggita Safitri · 2013 · Jurnal Dinamika Manajemen
Tujuan penelitian ini adalah untuk menguji pengaruh asimetri informasi terhadap underpricing. Penelitian ini menggunakan sampel 63 perusahaan yang melakukan penawaran umum perdana di Bursa Efek Indonesia dalam kurun waktu 2005-2010. Analisis data menggunakan regresi linier berganda, yaitu menguji proksi asimetri informasi yang terdiri atas ukuran perusahaan, umur perusahaan, proporsi saham yang ditawarkan kepada masyarakat, reputasi underwriter dan reputasi auditor terhadap underpricing. Hasil penelitian ini mengindikasikan bahwa reputasi underwriter dan reputasi auditor berpengaruh terhadap u
View details →Negative / Null Result ReportOpen accessMedicine
Zerrin Tuncer, Turhan Soylu · 2012 · Türk Oftalmoloji Dergisi
Pur po se: To evaluate the long-term results of rigid gas permeable (RGP) contact lenses in severe keratoconic eyes. Ma te ri al and Met hod: Severe keratoconic eyes with RGP contact lenses were evaluated retrospectively. Re sults: Long-term follow-up results of RGP contact lenses applied to 59 eyes of 42 patients (25 women, 17 men) with a diagnosis of severe keratoconus were analyzed. Follow-up period was 3 to 12 years (mean: 6.57±3.60). The mean age at first exam was 25.88±9.10 years, the mean corneal curve K1 was 6.49±0.40 mm and K2 was 5.91±0.40 mm. Mean visual acuities with spectacles and
View details →Negative / Null Result ReportOpen accessAccounting. Bookkeeping
Zahra Talei Gharegheshlaghi, farzad ghayour, Hamzeh Didar · 2019 · پژوهشهای حسابداری و حسابرسی عملیاتی و عملکرد
Decisions and thoughts of managers of organizations have a crucial role in advancing organizational goals. So identify their personal characteristics that influence their decisions and can be the reason for incompetence and managerial inadequacies in different levels of management and leadership of the organizations is important.Corporate owners use corporate governance mechanisms to reduce the opportunistic behavior of managers and protect the rights of stakeholders. In this regard, the present study aims to investigate the type and direction of the effect of management behavioral aspects on
View details →Negative / Null Result ReportOpen accessAgriculture
Haixing Zhang, Wei Shi, Shahzad Ali et al. · 2022 · Agronomy
Legume/maize intercropping has been practiced in many countries as a sustainable cropping system, but the effects of intercropping legumes with maize together with N application rates on biomass yield, quality, water-use efficiency (WUE), and nitrogen use efficiency (NUE) are limited under arid conditions in Northwest China. Field experiments were carried out in arid areas of Northwest China from 2019 to 2020 with three planting patterns (LM: Dolichos lablab ( Lablab purpureus L.)/silage maize ( Zea mays L.) intercropping; FM: Fodder soybean ( Glycine max L.)/silage maize intercropping; M: sil
View details →Negative / Null Result ReportOpen accessAccounting. Bookkeeping
Jeanni Otyne D. S., Alfira Sofia · 2026 · Jurnal Akademi Akuntansi
Purpose: This study aims to examine effect of ownership structure and social media exposure on Corporate Social Responsibility disclosure. Methodology/approach: Using purposive sampling, nine personal care companies listed on the Indonesia Stock Exchange (IDX) were selected over a three-year period, yielding 27 firm-year observations. Secondary data were sourced from annual reports, company official websites, and Instagram accounts. Data analysis employed descriptive statistics, classical assumption tests (normality, multicollinearity, autocorrelation, and heteroscedasticity), and multiple lin
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