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19,885 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Predictive Factors of Functional Prognosis in Patients with Rhegmatogenous Retinal Detachment Treated by Pars Plana Vitrectomy-A Retrospective Study.

Chereji G, Chelaru VF, Nicoară SD · 2026 · Diagnostics (Basel, Switzerland)

Background/Objectives : Rhegmatogenous retinal detachment (RRD) is a surgical emergency that causes vision loss if not properly treated. Pars plana vitrectomy (PPV) is the preferred procedure for most complex RRD cases, with a high success…

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Negative / Null Result ReportOpen accessMedicine

Genetically predicted TTK inhibition and its association with reduced breast cancer risk: a two-step Mendelian randomization study of potential gut microbiome mediation.

Liu J, Liu M, Xu Y et al. · 2026 · Clinics (Sao Paulo, Brazil)

Background BOS172722, a selective TTK inhibitor, shows promise for Breast Cancer (BC) treatment. The role of gut microbiota as a potential mediator in this process has not been established. This Mendelian Randomization (MR) study…

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Negative / Null Result ReportMedicine

Effects of different hyrax maxillary expansion protocols compared with novel magnetic expansion on the pharyngeal airway and maxillary sinus spaces: A retrospective CBCT-based observational study.

Algahefi AL, Alhammadi MS, Li Z et al. · 2026 · American journal of otolaryngology

Purpose To evaluate three-dimensional changes in the maxillary sinus (MS) and pharyngeal airway space (PAS) following rapid (RME), slow (SME), and magnetic maxillary expansion (MME) using cone-beam computed tomography (CBCT). Methods This…

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Negative / Null Result ReportOpen accessMedicine

Comparison of Lower Limb Muscle Strength Imbalances and Gait Performance in Postmenopausal Women with Healthy and Low Bone Mineral Density.

Svobodová L, Kasović M, Vodicka T et al. · 2026 · International journal of women's health

Introduction Osteoporosis and osteopenia increase the risk of fractures, impair physical function, and may lead to loss of independence in postmenopausal women. This study examined differences in muscle strength imbalances and gait…

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Negative / Null Result ReportOpen accessMedicine

Effect of Two Post-Curing Units on the Physico-Mechanical Properties of 3D-Printed Resins for Permanent Crown Fabrication.

Mujayridi M, Matinlinna J, Silikas N · 2026 · Materials (Basel, Switzerland)

Three-dimensional (3D) printing is increasingly used for the fabrication of definitive crowns; however, whether specific post-curing hardware is mandatory for clinical success remains a practical concern. This study provided a practical…

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Negative / Null Result ReportMedicine

Effect of oral health education by audio aids, braille, tactile models on the oral health status of visually impaired adults: a 6-month follow-up study.

Yıldırım D, Zorluoğlu SL, Navruz ES et al. · 2026 · BMC oral health

Background Oral and dental health education is typically delivered using visual methods on jaw models. However, these methods are insufficient for individuals with visual impairments. This study aims to contribute to the oral and dental…

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Negative / Null Result ReportOpen accessMedicine

Focus on comfort: the effect of focus language on postoperative hospital stay compared to the Numeric Rating Scale in children receiving postoperative care-a pre-post study.

Angenent A, Maaskant JM, Nieland L et al. · 2026 · European journal of pediatrics

This study evaluates the effect of a comfort assessment using focus language compared with pain assessment using the Numeric Rating Scale (NRS) on postoperative length of stay (LOS), analgesic use and patient and parental satisfaction.…

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Negative / Null Result ReportOpen accessMedicine

Early outcomes of transverse perineal support in obstructed defecation syndrome with pathological perineal descent; a prospective cohort study.

Azmy Basiouny HM, Shafik AA, Elbarmelgi MY et al. · 2026 · BMC surgery

Background While current surgical approaches for obstructed defecation syndrome (ODS) primarily target rectocele and rectal intussusception, excessive perineal descent (PD) may contribute to persistent symptoms and suboptimal surgical…

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Negative / Null Result ReportOpen accessMedicine

Assessment of changes in selected parameters of Arnett's soft tissue cephalometric analysis (STCA) in patients undergoing SARME/SARPE.

Nowak R, Olejnik A, Zawiślak E et al. · 2026 · Head & face medicine

Background Maxillary constriction in adults often requires surgically assisted maxillary expansion. While skeletal and dental changes are well described, soft-tissue effects remain less clear. This study evaluated soft-tissue changes using…

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Negative / Null Result ReportOpen accessMedicine

Impact of therapeutic oral health education program in individuals with systemic sclerosis: A prospective study.

Mahajan A, Upadhyay M, Reddy RN et al. · 2026 · Journal of education and health promotion

Background Systemic sclerosis is an autoimmune disorder characterized by progressive fibrosis which affects skin and internal organs. There is also involvement of oral cavity seen as microstomia which affects oral hygiene and subsequently,…

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Negative / Null Result ReportOpen accessMedicine

Assessment of apical debris extrusion with three nickel-titanium rotary systems using conventional and lyophilization-based quantification methods.

Hegde NN, Attavar S, Banerjee A et al. · 2026 · Journal of conservative dentistry and endodontics

Background Apical extrusion of debris during root canal preparation is inevitable and may contribute to postoperative pain and periapical inflammation. The extent of extrusion varies with instrument design and motion. ProTaper Next (PTN),…

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Negative / Null Result ReportOpen accessMedicine

Shear Bond Strength of a Light-Cured and a Dual-Cured Universal Adhesive to Primary and Permanent Dentin: An In Vitro Study.

Fousekis E, Arhakis A, Arapostathis K et al. · 2026 · Biomimetics (Basel, Switzerland)

The aim of the study was to evaluate the immediate and aged shear bond strength (SBS) of a dual-cured and a light-cured universal adhesive to primary and permanent dentin. Twenty caries-free primary molars and twenty permanent third molars…

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Negative / Null Result ReportOpen accessMedicine

Intraperitoneal Polypropylene Mesh in Clean, Potentially Septic, and Controlled Contamination Fields: An Experimental Rat Study.

Makrantonakis A, Mantzoros I, Ioannidis O et al. · 2026 · Medicina (Kaunas, Lithuania)

Background and Objectives : Intraperitoneal onlay mesh (IPOM) reduces ventral/incisional hernia recurrence but raises concern for adhesions and infection, particularly when the operative field is not strictly clean. We aimed to determine…

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Negative / Null Result ReportOpen accessMedicine

Prognostic Value of the Platelet-to-Lymphocyte Ratio in Patients With Acute Coronary Syndrome and Its Correlation With Angiographic Findings.

Seetharama DB, Prasad K, Prakash VR et al. · 2026 · Cureus

Introduction Acute coronary syndrome (ACS) is a major manifestation of coronary heart disease and is associated with significant morbidity and mortality. Inflammatory and thrombotic mechanisms play an important role in its pathogenesis.…

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Negative / Null Result ReportMedicine

The effect of three different root canal filling materials on postoperative pain in teeth with irreversible pulpitis: a randomized clinical trial.

Eminsoy Avcı AT, Yavuz B, Karakaya B et al. · 2026 · BMC oral health

Background This randomized clinical trial aimed to compare postoperative pain (PP) and analgesic consumption following single-visit root canal treatment using two calcium silicate-based sealers (BioMTA + and Well-Root PT) and one epoxy…

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