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19,885 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Episodic migraine is associated with a more atherogenic lipid profile rather than independent insulin resistance: a case-control study.

Szabóová S, Duraníková O, Örzsik B et al. · 2026 · Lipids in health and disease

Background Cardiometabolic factors may influence migraine biology through metabolic, inflammatory, and vascular mechanisms, but studies examining insulin resistance and dyslipidaemia in migraine have yielded inconsistent results, partly…

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Negative / Null Result ReportMedicine

Physical Activity Patterns and Kidney Function Changes Among Hispanic/Latino Adults: The Hispanic Community Health Study/Study of Latinos.

Rivas-Nieto AC, Alver SK, Mooney SJ et al. · 2026 · Journal of physical activity & health

Background Physical activity (PA) may be a modifiable factor for chronic kidney disease (CKD) prevention, but evidence specific to Hispanic/Latino populations is limited. Our objective was to examine associations between PA type/volume…

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Negative / Null Result ReportMedicine

Retrospectively reported childhood ADHD symptoms and addiction severity in emerging adults with substance use disorders: cross-sectional indirect associations through time perspective.

Demirci SC, Aşik UB, Menkü BE et al. · 2026 · BMC psychiatry

Background Symptoms of attention-deficit/hyperactivity disorder (ADHD) are commonly observed in individuals with substance use disorders (SUD) and may be associated with increased addiction severity. Time perspective is a potential…

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Negative / Null Result ReportMedicine

Relationship Between Standing Long Jump Performance and Health-Related Indicators and Lifestyle Factors in Chilean Adolescents: A Cross-Sectional Study.

Montalva-Valenzuela F, Guzmán-Muñoz E, Castillo-Paredes A et al. · 2026 · Healthcare (Basel, Switzerland)

Background: The standing long jump (SLJ) is a field-based test of lower-limb muscular fitness in youth and a proposed indicator of health-related physical fitness. However, evidence on its relationship with psychological, sleep, dietary,…

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Negative / Null Result ReportMedicine

Perinatal and Lifestyle Factors Associated with Childhood Alanine Aminotransferase Levels as an Early Indicator of Metabolic Dysfunction-Associated Steatotic Liver Disease: A Population-Based Study.

de Ruyter H, Aitokari L, Iqbal A et al. · 2026 · The Journal of pediatrics

Objective To investigate associations of perinatal and lifestyle factors with alanine aminotransferase (ALT) levels as an early indicator of metabolic dysfunction-associated steatotic liver disease (MASLD). Study design Data from the…

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Negative / Null Result ReportMedicine

Systemic inflammatory indices as predictors of adverse outcomes in pregnancies with vascular events: A retrospective cohort study.

Toptas GR, Firatligil FB, Ozdal BB et al. · 2026 · International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

Objective To investigate the association between systemic inflammatory indices, including the systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), and aggregate index of systemic inflammation (AISI), and…

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Negative / Null Result ReportMedicine

Assessing the essential parameters of race, ethnicity and geography in endometrial cancer and the impact on presentation, treatment and outcomes.

Jamieson A, Kwon J, Gao T et al. · 2026 · Gynecologic oncology

Background Race, ethnicity, and geography can impact cancer management, genomics and outcomes. We aimed to determine the ethnic and geographic diversity of endometrial carcinoma (EC) patients in our province and their impact on molecular…

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Negative / Null Result ReportMedicine

Identification of chrono-nutrition behavior patterns and their associations with sociodemographic characteristics, diet quality, and obesity.

Murakami K, Shinozaki N, Livingstone MBE et al. · 2026 · The British journal of nutrition

While chrono-nutrition behaviors are inter-related, few studies examined patterns of chrono-nutrition behaviors using a comprehensive set of these behaviors. This study aimed to identify chrono-nutrition behavior patterns and examine their…

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Negative / Null Result ReportMedicine

Relationships between rest-activity rhythms, cancer-related fatigue, and quality of life: Results from a time-restricted eating randomized controlled trial.

Kleckner AS, Zhou Y, Diaz-Mercado Y et al. · 2026 · Chronobiology international

Circadian rest-activity rhythms, or a person's consistency in their daily activity and rest patterns, can be quantified using various parametric and non-parametric methods. However, these methods are seldom applied to understand symptoms…

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Negative / Null Result ReportMedicine

IL-6 and TNFα are associated with depressive symptoms among men in a community-based cohort, with a tentative trend for IL-17A: Findings from the Shika Study in Japan.

Tsuboi H, Sakakibara H, Minamida-Urata Y et al. · 2026 · Neuro endocrinology letters

Objective Emerging evidence suggests that low-grade systemic inflammation contributes to depressive symptoms; however, population-based longitudinal evidence, particularly from community samples, remains limited. This study examined the…

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Negative / Null Result ReportMedicine

Outcomes of extremely preterm infants with neonatal hyperglycemia and hypernatremia: a retrospective cohort study.

Fursule A, Athalye-Jape G, Deepak D et al. · 2026 · Journal of perinatology : official journal of the California Perinatal Association

Objective To assess whether early hypernatremia (HN) and/or hyperglycemia (HG) in the first postnatal week are associated with adverse neurodevelopmental outcomes in extremely preterm (EP; Study design This was a single-center…

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Negative / Null Result ReportMedicine

Association between platelet indices and next-day bleeding and clotting in children and adults on extracorporeal membrane oxygenation: A retrospective study.

Chegondi M, Jawahar A, Badheka A et al. · 2026 · Perfusion

IntroductionBleeding and clotting phenotypes are common in patients supported with Extracorporeal Membrane Oxygenation (ECMO) and are associated with increased mortality. However, tools to distinguish bleeding from clotting phenotypes…

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Negative / Null Result ReportMedicine

Subclinical malaria in sickle cell disease in Northern Uganda: prevalence, predictors, and hematologic impact.

Matejak NJ, Ngolobe H, O'Connell CT et al. · 2026 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

Objectives Sickle Cell Disease (SCD), characterized by persistently low hemoglobin (Hb) and hematocrit levels, is among the leading causes of under-five mortality in high prevalence countries. Sub-Saharan Africa bears the highest burden of…

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Negative / Null Result ReportMedicine

Associations between attitudes and beliefs about the role of nutrition and diet quality with pain interference and physical function.

Fredhoff B, Bernstetter A, Fotiou H et al. · 2026 · Complementary therapies in clinical practice

Background and purpose Nutrition likely influences pain, but the role of patient beliefs remains understudied in musculoskeletal conditions. This study examined whether beliefs about the role of nutrition in pain, diet quality, and eating…

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Negative / Null Result ReportMedicine

Associations of preoperative patient mental health status, sociodemographic and clinical characteristics with baseline pain, function and satisfaction in patients undergoing revision rotator cuff repairs.

Streubel PN, Sahoo S, Zhang C et al. · 2026 · Journal of shoulder and elbow surgery

Background This study aimed to investigate the associations of general patient and disease-specific factors with baseline patient reported outcome measures (PROMs) in patients undergoing revision rotator cuff repair (RCR). Baseline…

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Negative / Null Result ReportMedicine

Individuals with posttraumatic stress disorder have increased beat-to-beat blood pressure variability.

McGranahan MJ, Sabino-Carvalho JL, Zanuzzi MG et al. · 2026 · American journal of physiology. Regulatory, integrative and comparative physiology

Individuals with posttraumatic stress disorder (PTSD) are at elevated risk for cardiovascular disease (CVD). Emerging research suggests that increased blood pressure variability (BPV) reflects abnormalities in autonomic regulation and may…

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Negative / Null Result ReportMedicine

Risk Factors for Recurrence and Complications Following Cytoreductive Surgery in Platinum-Resistant Ovarian Cancer: A Retrospective Cohort Study.

Wang L, Yao L, Wan J et al. · 2026 · Annali italiani di chirurgia

Aim This study aims to identify independent risk factors for tumor recurrence and postoperative complications in platinum-resistant ovarian cancer patients undergoing cytoreductive surgery. Methods This study retrospectively included 96…

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