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Browse the failure-mode index

20,253 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Effect of the Multicomponent Exercise Program MoveUS on the Kinematic Fatigue of People With Glenohumeral Instability: A Secondary Analysis From a Randomized Controlled Trial.

Ramírez-Pérez L, Cuesta-Vargas AI · 2026 · Physiotherapy research international : the journal for researchers and clinicians in physical therapy

Kinematic movement analysis is highly relevant in patients with glenohumeral instability, a pathology characterized by fatigue-induced slowing of repetitive movements. However, the optimal exercise approach for this symptom remains…

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Negative / Null Result ReportOpen accessMedicine

Fecal microbiota composition concerning body mass index and early-life factors in Mexican preschool-aged children: a cross-sectional study.

Hernández-Rodríguez D, Contreras A, Melgar Lalanne G et al. · 2026 · PeerJ

Background The gut microbiota maturation extends beyond the first two years of life. Early perinatal and postnatal factors may influence the child's nutritional status, which, in turn, can affect the composition of their gut microbiota.…

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Negative / Null Result ReportOpen accessMedicine

Effect of a One-Week Lubricant Pretreatment on Post-LASIK Dry Eye: Single-Center Randomized, Single-Masked Study With 1-Month Follow-Up.

Cañones-Zafra R, Allendes-Urquiza G, Muñiz C et al. · 2026 · Journal of ophthalmology

Purpose Our purpose is to report the results of a prospective study on ocular discomfort and objective tear film parameters (osmolarity and NIKBUT), in myopic patients, and observe the possible differences at 1 month between randomized…

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Negative / Null Result ReportMedicine

Could Autism Spectrum Disorder Be Associated With Craniosynostosis?

Still MEH, Alberts A, Nagda P et al. · 2026 · The Journal of craniofacial surgery

Introduction Craniosynostosis is a common pediatric condition that results in variable symptoms that range from asymptomatic cosmetic deformities to severe signs of intracranial hypertension. Little is understood about the relationship…

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Negative / Null Result ReportMedicine

Comparison of Nasal Tip Projection and Rotational Stability between Structural Rhinoplasty with Strut Graft and Preservation Rhinoplasty with Pitanguy Ligament Graft.

Farhadi F, Ahmadpour F, Nezafati S et al. · 2026 · Aesthetic plastic surgery

Background and aim The nasal tip plays a central role in facial aesthetics, and achieving long-term tip stability is a key objective in rhinoplasty. This study compared postoperative tip stability between structural rhinoplasty using a…

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Negative / Null Result ReportOpen accessMedicine

A chlorine releasing solution as an alternative for dental biofilm control.

Telles PYV, Oliveira VC, Geng Vivanco R et al. · 2026 · Scientific reports

To evaluate the antibiofilm activity of a chlorine-releasing solution (CRS) and its in vitro effects on enamel color stability, surface roughness, and microhardness. A mixed biofilm composed of Staphylococcus aureus, Candida albicans, and…

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Negative / Null Result ReportOpen accessMedicine

Comparison of Postoperative Analgesic Efficacy of Two Intrathecal Morphine Doses (75 μg vs 100 μg) for Cesarean Delivery: A Double-Blind Randomized Study.

Veraza JA, Martinez MA, Angulo P et al. · 2026 · Cureus

Background Intrathecal morphine remains a cornerstone of post-cesarean analgesia due to its prolonged spinal effect; however, its use is limited by dose-dependent adverse effects. Contemporary practice trends favor dose minimization, yet…

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Negative / Null Result ReportOpen accessMedicine

Do the Pre-Existing Class III and Class V Composite Restorations Affect the Sealing Ability and Integrity of 3D-Printed Laminate Veneer Margins? An In Vitro Study.

Qaraghuli AM, Cagidiaco EF, Ferrari M · 2026 · Journal of functional biomaterials

Background: The application of veneer restorations over previously composite-restored anterior teeth presents significant clinical challenges, particularly in achieving optimal marginal sealing. Aim: This in vitro study aimed to evaluate…

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Negative / Null Result ReportOpen accessMedicine

Current status of 5-aminosalicylic acid in Crohn's disease treatment: a nationwide survey and analysis of perspectives and practice patterns among inflammatory bowel disease physicians.

Li Y, Chen C, Wang C · 2026 · Frontiers in gastroenterology (Lausanne, Switzerland)

Objective To investigate the perspectives and clinical practice patterns of inflammatory bowel disease (IBD) physicians regarding the use of 5-aminosalicylic acid (5-ASA) in Crohn's disease (CD). Methods A 21-item questionnaire was…

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Negative / Null Result ReportMedicine

Acute effects of the FIFA 11 + kids warm-up program compared with a judo-specific warm-up on explosive and functional performance in youth judo athletes: a randomized crossover study.

Mor H, Şar H, Arslan T et al. · 2026 · BMC sports science, medicine & rehabilitation

Background The FIFA 11 + Kids (FIFA 11+) warm-up program is effective for injury prevention and to enhance sports performance, including vertical jump (VJ), sprint, balance, and agility. However, no previous study has examined the acute…

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Negative / Null Result ReportOpen accessMedicine

Delayed orocecal transit in pediatric gut-brain interaction disorders: A comparative study using the lactulose breath test.

Devanarayana NM, Rajindrajith S, de Silva DGH et al. · 2025 · World journal of gastrointestinal pathophysiology

Background Functional abdominal pain disorders (FAPDs) are common gut-brain interaction disorders with unclear pathophysiology. While impaired gastrointestinal motility is thought to play a key role, small intestinal dysmotility remains…

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Negative / Null Result Report

A population genetic study of Fusarium graminearum , the causal agent of Fusarium Head Blight, provides insights into patterns of inoculum dispersal in wheat fields at a regional scale

Nguyen TBH, Le Floch G, Henri-Sanvoisin A et al. · 2025 · Preprint

ABSTRACT Fusarium graminearum is the primary pathogen responsible for Fusarium Head Blight (FHB) in cereals, causing yield losses and mycotoxin contamination. The present study investigated the genetic diversity and population structure of…

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Negative / Null Result ReportOpen accessMedicine

Effect of different feed particle size on digestive tract morphology, digesta viscosity, nutrient retention, and blood biochemical parameters in slow-growing broiler chickens.

Novotný J, Čumplík L, Horáková L et al. · 2026 · Veterinary and animal science

The study evaluated the effect of feed particle size on health and performance indicators in slow-growing broiler chickens. Performance traits, digestive tract morphology, digesta viscosity, nutrient retention, and blood biochemical…

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Negative / Null Result ReportOpen accessMedicine

Culture medium influences detectability of antimicrobial effects of autologous platelet concentrates against anaerobic periodontal pathogens.

Jansen EE, Braun A, Jansen P et al. · 2026 · BMC oral health

Background Autologous platelet concentrates (PRP, PRF, i-PRF) represent blood-derived biomaterials that have been reported to exhibit antimicrobial activity against oral microorganisms in vitro. In diffusion-based assays, visualization of…

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Negative / Null Result ReportMedicine

Effects of lower limb joint manipulation on squat strength and ankle range of motion: a sham-controlled double-blind randomised cross-over trial.

Morley-Hart R, Losco B, Dempsey AR et al. · 2026 · Chiropractic & manual therapies

Background The back squat is a commonly prescribed exercise for developing lower body strength. The ability to squat can be affected by reduced ankle dorsiflexion range of motion (DF-ROM), leading to limited squat depth and dysfunctional…

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Negative / Null Result ReportOpen accessMedicine

Cerebroplacental Ratio in Monochorionic Diamniotic Twin Pregnancies with and Without Gestational Diabetes: A Longitudinal Cohort Study.

Yerlikaya-Schatten G, Adamovic M, Catic A et al. · 2026 · Journal of clinical medicine

Objective: To investigate whether gestational diabetes mellitus (GDM), including insulin-treated GDM, affects cerebroplacental ratio (CPR) values in monochorionic diamniotic (MCDA) twin pregnancies. Methods: This retrospective…

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