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Browse the failure-mode index

19,885 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Low-Volume Versus Standard-Volume Pericapsular Nerve Group Block with and Without Dexamethasone for Postoperative Analgesia After Total Hip Arthroplasty: A Randomized Controlled Trial.

Reysner, Ciftci, Alver et al. · 2026 · Journal of clinical medicine

Background: The pericapsular nerve group block provides motor-sparing analgesia after total hip arthroplasty, but the optimal injectate volume and the role of dexamethasone remain unclear. Methods: In this prospective, randomized,…

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Negative / Null Result ReportMedicine

Hope for Romantic Relationships: Validation of a Brief Scale.

Marici, Marina, Cormoș · 2026 · Behavioral sciences (Basel, Switzerland)

This study aimed to develop and validate a brief measure of hope for romantic relationships (HRR), conceptualized as a future-oriented evaluation of relational continuity and quality. The sample consisted of 525 participants. Exploratory…

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Negative / Null Result ReportMedicine

The Effect of Acupressure on Procedural Pain, Anxiety, and Hemodynamic Parameters During Chest Tube Removal in Open-Heart Surgery Patients: A Randomized Sham-Controlled Study.

Kandemir, Yüksel, Çam Yanık et al. · 2026 · Pain management nursing : official journal of the American Society of Pain Management Nurses

Patients undergoing open-heart surgery often experience procedural pain and anxiety during chest tube removal (CTR), which can lead to serious complications, along with potential changes in hemodynamic parameters such as blood pressure,…

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Negative / Null Result ReportMedicine

Effects of Tele-Pilates Exercise on Menopausal and Urogenital Symptoms and Psychosocial Outcomes in Postmenopausal Women: A Randomized Controlled Trial.

Arslan, Tufekci, Acar et al. · 2026 · International urogynecology journal

This study aimed to examine the effects of tele-Pilates exercise on menopausal symptoms, quality of life, depression, and anxiety levels in postmenopausal women. Forty postmenopausal women were separated into two groups: as tele-Pilates…

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Negative / Null Result ReportMedicine

Characterizing the nasal microbiome using a nasal allergen challenge model.

Linton, Sjaarda, Hossenbaccus et al. · 2026 · The Journal of allergy and clinical immunology

The role of the nasal microbiome in allergic rhinitis (AR), particularly following direct allergen exposure using a controlled model, is incompletely understood. Understanding microbiome dynamics after allergen challenge could provide…

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Negative / Null Result ReportMedicine

Three-Season Analysis of Physical Performance in Professional English Football: Influence of Match Outcome, Match Location, and Players' Position During Official Competitions.

Beato, Allen, Jamil et al. · 2026 · Journal of strength and conditioning research

Beato, M, Allen, M, Jamil, M, and Vicens Bordas, J. Three-season analysis of physical performance in professional English football: Influence of match outcome, match location, and players' position during official competitions. J Strength…

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Negative / Null Result ReportMedicine

Surgical strategy and prognostic factors in very elderly (≥ 75 Years) patients with stage I NSCLC: insights from a propensity score-matched analysis.

Lee, Chao, Shen et al. · 2026 · BMC pulmonary medicine

BACKGROUND: The optimal surgical strategy for very elderly patients (≥ 75 years) with stage I non–small cell lung cancer (NSCLC) remains uncertain. METHODS: We retrospectively analyzed 390 patients with pathologic…

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Negative / Null Result ReportMedicine

Impact of the risk-treatment paradox on in-hospital and long-term outcomes in patients with very high-risk non-ST-elevation acute coronary syndrome.

Nesova, Vorobeva, Ryabov · 2026 · The Indian journal of medical research

Background and objectives The risk-treatment paradox (RTP) has not been studied in very high-risk patients with non-ST-elevation acute coronary syndrome (NSTE-ACS). We aimed to describe the cohort of very high-risk NSTE-ACS patients,…

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Negative / Null Result ReportMedicine

Adjuvant capecitabine in women with triple-negative breast cancer with residual disease after carboplatin-containing neoadjuvant chemotherapy.

Tavares, Ramalho, da Silva et al. · 2026 · Breast cancer research and treatment

Triple-negative breast cancer (TNBC) is an aggressive subtype characterized by early relapse and limited therapeutic options. Carboplatin added to anthracycline/taxane neoadjuvant chemotherapy (NACT) raises pathologic complete response…

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Negative / Null Result ReportMedicine

Investigating the necessity of preoperative coronary angiography for infection-related cardiac implantable electronic device explantation.

Caldonazo, Scheler, Fischer et al. · 2026 · American heart journal plus : cardiology research and practice

Device-associated endocarditis is a potentially life-threatening condition that typically requires the removal of the cardiac implantable electronic device (CIED). The role of routine coronary angiography (CAG) as part of preoperative…

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Negative / Null Result ReportMedicine

The efficacy of acetic acid and citric acid on calcium silicate based cement removal from root canals and their effect on dentine structure - an in vitro study.

Alzraikat, Al-Hiyasat, Jamous et al. · 2026 · Biomaterial investigations in dentistry

This study evaluated the effectiveness of acids on calcium silicate cement surface hardness, perforation, and their impact on root dentine microstructure. Root dentine discs were exposed to hydrochloric, acetic, and citric acids. Fourier…

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Negative / Null Result ReportMedicine

Effects of omega-3 fatty acid supplementation on heart rate variability.

Atef Abdelsattar Ibrahim, Gouda Kamal, Zid et al. · 2026 · World journal of clinical pediatrics

Obesity and overweight are major public health challenges and are associated with autonomic imbalance and decreased heart rate variability (HRV), a non-invasive indicator of cardiovascular risk. Omega-3 polyunsaturated fatty acids have…

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Negative / Null Result ReportMedicine

Risk Factors Associated with Mortality in Nosocomial Stenotrophomonas maltophilia Pneumonia: A Single-Center Retrospective Study.

Yıldız, Top, Yıldız et al. · 2026 · Mediterranean journal of hematology and infectious diseases

Stenotrophomonas maltophilia ( S. maltophilia ) is a multidrug-resistant pathogen frequently isolated in hospital-acquired pneumonia and represents a significant clinical challenge. This study aimed to investigate the risk factors…

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Negative / Null Result ReportMedicine

Inpatient Opioid Use in Head and Neck Microvascular Free Flap Reconstruction.

Timothee, Bliss, Blumenthal et al. · 2026 · Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

The primary objective is to determine whether patients undergoing osseous microvascular free flap reconstruction of head and neck defects have higher inpatient pain requirements than those undergoing nonosseous reconstruction. Secondary…

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