20,253 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Michelutti N, Baud A, Meyer-Jacob C et al. · 2026 · Preprint
Abstract The “top–bottom” approach in paleolimnology provides a rapid means of assessing environmental change by comparing modern surface sediments with deeper intervals assumed to pre-date major anthropogenic disturbances (ca. pre-1880).…
View details →Phan TH, Phan MQ · 2026 · La Clinica terapeutica
Background Residual cardiovascular risk after acute myocardial infarction (AMI) is driven not only by dyslipidemia but also by systemic inflammation. High-sensitivity C-reactive protein (hs-CRP) and low-density lipoprotein cholesterol…
View details →Xiao H, Zeng X, Pang Q et al. · 2026 · Transplant immunology
Background Sodium-glucose cotransporter-2 inhibitors (SGLT2i) yield additional cardiorenal benefits beyond glycemic control. Emerging evidence suggests that SGLT2i have potential benefits in organ transplantation, though causal…
View details →Park M, Park H, Baek IH et al. · 2026 · Journal of patient safety
Objectives Erythropoiesis-stimulating agents (ESAs), classified as long-acting or short-acting, is a primary treatment for anemia in chronic kidney disease and chemotherapy. Given ongoing safety concerns regarding cardiovascular events and…
View details →Tulsian V, Kant R, Patnaik I et al. · 2026 · Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology
Background and objectives Helicobacter pylori infection is highly prevalent globally. Standard bismuth quadruple therapy is commonly used in India, but there are growing concerns regarding the emergence of anti-microbial resistance and…
View details →Hong WJ, Huang JM, Liu YH et al. · 2025 · Aesthetic plastic surgery
Background The postauricular injection technique is a needle-based technique that places soft tissue fillers behind the ears into the supra-periosteal plane of the mastoid process of the temporal bone. The resulting clinical effect pushes…
View details →Morris JS, Rajshekhar S, Gremmo G et al. · 2026 · European journal of obstetrics, gynecology, and reproductive biology
Deep endometriosis (DE) is established to cause chronic pelvic pain (CPP), lower urinary tract symptoms (LUTS) and altered bowel function. Although the aim of surgical excision is often to relieve CPP, evidence suggests it could also…
View details →Sit B, Sanderlin AG, Zhu CY et al. · 2025 · Preprint
Obligate intracellular bacterial pathogens cannot grow extracellularly, a trait that renders them highly understudied, but also endows them with unexpected host dependencies. Here, using the emerging obligate intracellular tickborne…
View details →Reiter T, Dörrler AL, Hasenauer N et al. · 2026 · European journal of nuclear medicine and molecular imaging
Introduction Acute myocardial infarction (AMI) triggers local inflammation in the injured myocardium, followed by a systemic inflammatory response of lymphatic organs. This prospective trial (NCT05519735) focused on molecular imaging of…
View details →Shabbir A, Abbas G, Alharby HF et al. · 2026 · International journal of phytoremediation
Heat stress and soil arsenic (As) contamination are resulting in severe decline in crop production around the world. The present experiment aimed to assess physiological and biochemical changes induced by the combination of As and heat…
View details →Jeneson J, van den Berg-Faay A, Hooijmans M · 2025 · Preprint
We employed interleaved dynamic 1H magnetic resonance imaging (MRI) and 31P MR spectroscopy in combination with arm-cycling to investigate correlations of exercise hyperemia and muscle energetics in the triceps brachii (TB) muscle of the…
View details →Jacobsen P, Cloos L, vanpaemel w et al. · 2025 · Preprint
Affective inertia – the extent to which changes in one’s affective state persist over time – isan important feature of affect dynamics. It is often examined using experience sampling studies thatcapture momentary affect multiple times per…
View details →Son AJ, Rapp E, Wiezorek A et al. · 2026 · JCI insight
Stopping and restarting GLP-1 weight-loss drugs in mice made them less effective over time and increased fat gain compared with continuous treatment.
View details →Cottom JM, Verdoni TJ · 2026 · The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
Background Total ankle replacement continues to find significantly increased utilization as the technology advances. While there are different systems on the market, most are implanted through an anterior incisional approach just lateral…
View details →Varughese VJ, Richardson C, Pollock J et al. · 2025 · Preprint
ABSTRACT INTRODUCTION MitraClip ® (MC) placement has been extensively used as an intervention for mitral transcatheter edge-to-edge repair (mTEER) for functional mitral regurgitation (FMR). The aim of our study is to analyze the…
View details →El-Haffaf I, Marsot A, Paillault A et al. · 2025 · Canadian journal of physiology and pharmacology
In this study, we evaluate the exposure and pharmacokinetic/pharmacodynamic target attainment of meropenem in critically ill patients. We conducted a prospective observational study in two Canadian intensive care units (ICUs) from January…
View details →Beijer G, Swartling M, Nielsen EI et al. · 2025 · Critical care (London, England)
Background Standard dosing regimens of meropenem and piperacillin-tazobactam frequently fail to achieve targeted plasma concentrations in critically ill patients. Extended or continuous regimens are often used to improve target attainment.…
View details →Jang S, Kim D, Kim T et al. · 2025 · Nanotechnology
In this study, a Cleaning Endpoint Evaluation Sensor (CEES) was developed and applied to improve the monitoring accuracy and uniformity control in the cleaning processes for NF 3 -based remote plasma sources in semiconductor equipment.…
View details →Wang J · 2025 · Scandinavian journal of trauma, resuscitation and emergency medicine
This comment critiques a trial comparing intranasal dexmedetomidine (DEX) and esketamine (sKET) for pediatric procedural sedation. Despite a large effect size, the small sample (n = 29) likely caused false-negative results (p = 0.09),…
View details →Bacon EK, Parnell D, Muscatello G et al. · 2025 · Journal of equine veterinary science
Background The ongoing discussion surrounding the well-being of retired racehorses underscores the importance of implementing effective rehoming strategies that prioritise animal welfare. A significant knowledge gap persists regarding…
View details →Seidel M, Barns H, Klostermann C et al. · 2025 · Journal of Nutrition Education and Behavior
Nationwide, 41% - 48% of students on college campuses are food insecure (FI). These students are more likely to do poorly in school and drop out than their food secure (FS) peers. In 2017, 30% of students at Chatham University (CU), a…
View details →Mattiuzzi C, Lippi G · 2025 · Preprint
Background: Earlier studies suggested that coronavirus disease 2019 (COVID-19) mortality may vary by the day of the week, possibly due to healthcare system workflows or reporting delays. This study aimed to assess whether such day-of-week…
View details →Lang A, Gabriel H, Meister TL et al. · 2026 · The Journal of hospital infection
Background Candida (Candidozyma) auris is a globally emerging multidrug-resistant fungal pathogen that causes nosocomial outbreaks in healthcare facilities. Aim To evaluate the susceptibility of different C. auris clade strains (I to V)…
View details →Felicioni F, Nivia-Riveros JA, Caldeira-Brant AL et al. · 2026 · The Journal of nutritional biochemistry
Proper fetal development depends on maternal nutrition. We investigated the placental morphofunctional adaptations to a low-protein diet, and their impact on fetal and newborn outcomes. Swiss mice were fed either normal (NPD, 20% crude…
View details →Metzler YA, Alyan E, Taibi Y et al. · 2025 · Preprint
Abstract Occupational psychology frequently aggregates self-reported work characteristics to higher-level units like occupations, assuming them to represent a distinct entity. However, concerns persist regarding reliability and…
View details →Boles B, Gardner JA, Rehder CW et al. · 2025 · Archives of pathology & laboratory medicine
Context.— The joint College of American Pathologists/American College of Medical Genetics and Genomics Cytogenetics Committee works to ensure competency and proficiency of clinical cytogenetics testing laboratories through proficiency…
View details →Tsuchie R, Hashimoto Y, Abiko M et al. · 2026 · Neurologia medico-chirurgica
Anatomical variations in the middle cerebral artery affect outcomes of mechanical thrombectomy in M1 occlusion cases. However, the relationship between middle cerebral artery branching patterns-specifically trifurcation and bifurcation-and…
View details →Umeaghadi CF, Taylor JG, Yao S et al. · 2026 · Patient preference and adherence
Adherence surveys can be lengthy due to the high number of potential risk factors to be analyzed. As a result, researchers often reduce items into conceptual domains (eg, beliefs, economic factors) to overcome power constraints or focus…
View details →Reiter T, Dörrler A, Hasenauer N et al. · 2025 · Preprint
ABSTRACT Background Acute myocardial infarction (AMI) triggers local inflammation in the injured myocardium, followed by a systemic inflammatory response of lymphatic organs. This prospective trial investigated whether molecular imaging of…
View details →Eckert L, Miller JS, Fitzpatrick JL et al. · 2025 · Evolution; international journal of organic evolution
Reproductive accessory glands are organs involved in reproduction that do not directly produce or release gametes but can play crucial roles in securing reproductive success. In fishes, the 2 leading hypotheses about why accessory glands…
View details →