20,253 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Ehinger BV, Bonasch H · 2023 · Preprint
Abstract 1 Some participants consistently show large, and others small activations in Electroencephalography (EEG) and other neuroimaging studies. Similarly, decoding accuracies in Brain-Computer-Interface (BCI) vary between subjects, in…
View details →Scott MB, Kammermeier PJ · 2024 · Pharmaceuticals (Basel, Switzerland)
The gabapentenoids such as gabapentin (GP) and pregabalin are approved for the treatment of chronic pain, but their utility is limited by persistent side effects. These adverse effects result from GPs affecting many types of neurons and…
View details →Choneva M, Delchev S, Hrischev P et al. · 2024 · International journal of molecular sciences
Diabetic cardiomyopathy is a major etiological factor in heart failure in diabetic patients, characterized by mitochondrial oxidative metabolism dysfunction, myocardial fibrosis, and marked glycogen elevation. The aim of the present study…
View details →Ebrahimi F, Kangari H, Akbarzadeh-Bagheban A et al. · 2025 · International journal of ophthalmology
Aim To evaluate the effects of polarized and non-polarized sunglasses on visual functions, including distance and near visual acuity, phoria, stereopsis and contrast sensitivity across five spatial frequencies (1.5, 3, 6, 12, 18…
View details →Zeng X, Chen Y, Lin S et al. · 2026 · Frontiers in surgery
Purpose This study aimed to investigate the influence of previous percutaneous renal procedures on the outcome of ultrasound (US)-guided percutaneous nephrolithotomy (PCNL) in patients with upper urinary tract stones. Patients and methods…
View details →Lartey NL, Nyarko ENY, Asare-Anane H et al. · 2023 · Preprint
ABSTRACT Background and aim The lack of standardization and scientific validation of the use of most plant extracts leads to toxicity problems. The stem bark extract of Annickia polycarpa has been shown to possess antioxidant,…
View details →Kazmi S, Sanford E, Rammaha ZA et al. · 2025 · International journal of molecular sciences
Oral squamous cell carcinoma (OSCC) is marked by profound differences in survival between the localized and disseminated disease, estimated to result in a 70% and less than a 40% five-year survival rate with surgical and/or radiation…
View details →Dicker D, Tamir O, Lieberman-Segal G et al. · 2023 · The Israel Medical Association journal : IMAJ
Background In 2019, 1 mg subcutaneous semaglutide was registered for the treatment of diabetes in Israel. Recognition of its effect on weight has led to its use as a treatment for obesity. Objectives To explore physicians' pre-therapy…
View details →Rolig AS, Ziglari T, McGee GH et al. · 2026 · Scientific reports
The tumor microenvironment (TME), which heavily influences immune checkpoint blockade (ICB) efficacy, is shaped by host-microbe interactions. Endogenous intratumoral bacteria have been implicated in efficacy of ICB, such as anti-PD-1…
View details →Hauber MM, Nordahl O, Todisco V et al. · 2026 · PloS one
Many coregonine species have declined drastically across the Northern Hemisphere, including populations of Coregonus maraena (whitefish) in the Baltic Sea, and the mechanisms leading to these declines are not well investigated. An abrupt…
View details →Marquis-Gravel G, Tong G, Dodd M et al. · 2025 · Journal of the Society for Cardiovascular Angiography & Interventions
Background Coronary artery bypass grafting (CABG) improves survival compared with optimal medical therapy (OMT) alone in patients with ischemic left ventricular systolic dysfunction (iLVSD), but percutaneous coronary intervention (PCI) did…
View details →Shahid N, Kim CH, Jabilona KB et al. · 2026 · PloS one
Tyrosine kinase inhibitors (TKI) are often used in combination with other chemotherapeutic nucleoside/nucleobase analogues, such as gemcitabine and 6-mercaptopurine, in the treatment of various cancers. Past studies have shown that several…
View details →Lubineau M, Watkins CP, Glasel H et al. · 2023 · Proceedings. Biological sciences
Does word flickering facilitate reading? Despite a lack of scientific evidence, flickering glasses and lamps for dyslexia are being marketed in various countries. We conducted four experiments to assess their efficacy. Two experiments…
View details →Salerno JW, Xu S, Rainforth M et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives : Cardiovascular disease (CVD) is the leading cause of death globally. The World Health Organization has called for investigations into traditional systems of medicine for CVD prevention. Ayurveda includes a…
View details →Stark R, Zigman JM, Andrews ZB · 2025 · Journal of neuroendocrinology
The olfactory bulb (OB) is an emerging neuroendocrine centre regulating appetite, metabolism, and behaviours such as those linked to anxiety, motivation and spatial navigation. These processes are likely mediated by one or more of the many…
View details →Liu S, Hu S, Chen J et al. · 2025 · Psychological research
Previous research has shown that the addition of happy or angry expressions to other-race faces can assist infants in overcoming the perceptual narrowing of face race and reinstating their recognition of other-race faces. In the present…
View details →Draper B, Wand APF · 2025 · Current opinion in psychiatry
Purpose of review Depression and physical illnesses have long been recognized as risk factors for suicidal behaviour in late life. Qualitative studies have previously identified frailty as being an issue in late life suicidal behaviour,…
View details →Beirowski B, Huang H, Babetto E · 2026 · eLife
Axon degeneration (AxD), accompanied by glial remodeling, is a pathological hallmark of many neurodegenerative diseases, leading to the disruption of neuronal connectivity. Understanding the mechanisms in neurons and glia that regulate AxD…
View details →Levin ME, Mukasa MN, Bowers EM et al. · 2025 · Behavioral sciences (Basel, Switzerland)
Adherence challenges are common among digital mental health interventions (DMHIs). Single-session DMHIs may help by providing a low-intensity intervention that takes less time to complete. This pilot randomized controlled trial sought to…
View details →Lunde P, Finbråten HS, Pripp AH et al. · 2025 · International journal of cardiology. Cardiovascular risk and prevention
Background and aims Adherence to treatment is a significant challenge for patients with cardiac disease. Optimizing health literacy (HL) is essential in this context. Mobile health (mHealth) interventions have been suggested to improve…
View details →Ferro M, Cilla S, Macchia G et al. · 2026 · Cancer reports (Hoboken, N.J.)
Background This study investigates the impact of radiotherapy (RT) on fatigue levels in prostate cancer (PC) patients, considering the significant physical and psychological impact of fatigue associated with cancer and its treatments.…
View details →stocker t · 2026 · Preprint
Hyperlactatemia, and/or lactic acidosis, is a common complication in wildlife due to the sensitivity of these species to capture induce complications. The treatment of lactic acidosis in humans is equally as controversial as in veterinary…
View details →Warren WG, Papagianni EP, Hale E et al. · 2022 · Frontiers in pharmacology
Endocannabinoid transmission is emerging as a target for treating anxiety-related disorders, given its regulation of fear extinction. Boosting anandamide levels via inhibition of its metabolism by fatty acid amide hydrolase (FAAH) can…
View details →Khalid E, Vijayan MM · 2025 · Frontiers in endocrinology
Introduction Although the Crh-Crhr1 system is the proximal trigger for the stressor-induced corticosteroid release, its role in initiating the fight-or-flight response to an acute stressor is unclear. We hypothesized that the Crh-Crhr1…
View details →Ouerghi N, Abassi W, Jebabli N et al. · 2026 · Sports (Basel, Switzerland)
The study investigated the effects of high-intensity interval training (HIIT) on cardiorespiratory fitness, hormonal, and psychological markers in adolescents. Twenty-eight healthy male adolescents were randomized to a HIIT group or a…
View details →Toledo FV, Meletti JFA, Silva LMC et al. · 2026 · Brazilian journal of anesthesiology (Elsevier)
Introduction Surgery remains one of the most important treatments for breast cancer. In this context, the quality of postoperative recovery has become a key concern. Adequate control of acute pain is essential to optimize patient comfort…
View details →Salihu AT, Usman JS, Hill KD et al. · 2023 · Experimental brain research
The ability to control balance and prevent falls while carrying out daily life activities may require a predominantly controlled (cognitive) or automatic processing depending on the balance challenge, age, or other factors. Consequently,…
View details →Tatsuoka Y, Zembrzuski KJ, Natalini JG et al. · 2025 · Journal of clinical medicine
Background: Primary graft dysfunction (PGD) is the leading cause of early mortality after lung transplantation. Albumin is commonly used during lung transplantation to maintain intravascular volume while minimizing total intravenous fluid…
View details →Berge M, Hultgren O, Hugosson S et al. · 2026 · Scientific reports
There are large variations in how individual patients respond to allergen immunotherapy (AIT) against grass and/or birch allergy. There are currently no reliable biomarkers to predict which patients are likely to benefit from the…
View details →Mariani C, Al Dababsekh A, Carta F et al. · 2025 · Medicina (Kaunas, Lithuania)
Background and Objectives : Hemostasis during thyroid surgery is crucial to avoid postoperative complications, particularly hematoma, which can cause life-threatening airway compromise. Arista™ AH, a plant-based absorbable hemostatic…
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