19,885 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Lindsley IC, Juman MM, Seifert SN et al. · 2026 · PLoS neglected tropical diseases
Large host-virus association databases are increasingly used to explore broad questions in disease ecology, particularly around host range, pathogen diversity, and the potential for spillover. While these databases have been instrumental…
View details →Wright L, Hamze J, Nagrani TR et al. · 2026 · Preprint
Abstract Background Coronary artery disease (CAD) places a disproportionate burden on rural Appalachian communities. Scioto County, Ohio has among the highest rates of CAD-related hospitalizations in the state, approaching double the…
View details →Ibrahim M, Mostafa D, Manie EA et al. · 2026 · British poultry science
1. This study used unvaccinated sentinels plus Avian Influenza Virus (AIV) specific ELISA for differentiating infected from vaccinated animals (DIVA). Birds assessed were from 10 broiler flocks (F1-F10), three layer (F11-F13) and two…
View details →Tavoly M, Jørgensen CT, Sandblad KG et al. · 2026 · Research and practice in thrombosis and haemostasis
Background It has been suggested that D-dimer testing should be avoided in patients with prolonged symptoms, as results may yield false negatives. However, the evidence supporting this recommendation is limited. Objectives This study…
View details →Otwell T, Knight B, Coryell M et al. · 2025 · Frontiers in cellular and infection microbiology
Molecular diagnostic assays are critical tools to test, diagnose and treat infectious and other diseases. For example, PCR test results have been extremely valuable during the COVID-19 pandemic, not only to provide appropriate health care…
View details →Gudmundsdottir H, Hernandez-Delima FJ, McDowell BC et al. · 2026 · Surgery
Background Regional lymph node involvement impacts prognosis for patients with pancreatic neuroendocrine tumors and may influence management decisions for small tumors. Conventional cross-sectional imaging modalities have low sensitivity…
View details →Khoshakhlagh M, Dehghani T, Alizadeh A et al. · 2026 · Iranian journal of pathology
Background & objective Real-time PCR is widely used to detect SARS-CoV-2, the virus responsible for COVID-19, but false-negative results can occur even with internal controls. This study aimed to investigate the impact of using alternative…
View details →Cañete FT, Williams L, Parry R et al. · 2026 · Forensic science international. Synergy
The Phadebas® Forensic Press Test (PFPT) is widely employed in forensic laboratories for presumptive saliva screening by observation of α-amylase activity. This enzyme hydrolyses starch embedded in the test paper, resulting in a blue…
View details →Lesmanawati DAS, Widiasta A, Ghrahani R et al. · 2026 · Preprint
Abstract Background Patients with systemic lupus erythematosus (SLE) are at increased risk of tuberculosis (TB) because of disease-related immune dysregulation and prolonged immunosuppressive therapy. Screening for latent TB infection…
View details →Liu M, Kong L, Sun W et al. · 2026 · Journal of immunotherapy (Hagerstown, Md. : 1997)
To investigate the clinical profile of nivolumab-induced autoimmune hemolytic anemia (AIHA) and to reveal the diagnostic and therapeutic patterns of this disease. Articles on nivolumab-induced AIHA published before October 31, 2025 were…
View details →Costa M, Rodrigues P, Araújo B et al. · 2026 · Diagnostic microbiology and infectious disease
Cryptococcal meningitis is a life-threatening opportunistic infection in advanced HIV disease. Cryptococcal antigen (CrAg) detection by lateral flow assay (LFA) is the diagnostic cornerstone, offering high sensitivity and specificity.…
View details →Li QX, Luo LZ · 2026 · BMC infectious diseases
Background Cutaneous infections caused by non-tuberculous mycobacteria (NTM) are rare. Atypical clinical manifestations and the need for precise microbiological identification often result in misdiagnosis and underdiagnosis. Case…
View details →Gambuś K, Moszczyński K, Popovchenko S et al. · 2026 · Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery
Introduction Accurate assessment of mediastinal lymph node involvement is crucial for treatment planning in lung cancer. Combined endobronchial and endoscopic ultrasound (CUS) offers high sensitivity and negative predictive value (NPV),…
View details →Alger JR, Gupta I, Farkouh L et al. · 2026 · Preprint
Background Prior neuroimaging suggests brain differences between children with attention deficit hyperactivity disorder due to prenatal alcohol exposure (ADHD+PAE) and non-exposed children with ADHD due to other, e.g., familial, causes…
View details →Dellbrügge F, Schaumann N, Kruppa M et al. · 2026 · Pneumologie (Stuttgart, Germany)
Abstract We present the case of a 39-year-old Indian female patient diagnosed with tuberculous mastitis and lymph node tuberculosis. The patient had a history of tuberculosis infection treatment as a newborn. She initially presented with…
View details →Li X, Huang Y, Hao J et al. · 2026 · Current HIV research
Background Married Men who have Sex with Men (MSM) constitute a bridge population for HIV diffusion into low-risk groups, with spousal non-disclosure rates exceeding 60% in China. It will increase the risk of secondary transmission within…
View details →Tsang SM, Merino Gutierrez V, Yu J et al. · 2026 · Veterinary sciences
Canine babesiosis caused by Babesia gibsoni is prevalent in Hong Kong. While molecular diagnosis via PCR is highly sensitive, it typically requires reference laboratory access, delaying clinical decisions. This study evaluated the…
View details →Hijaze E, Razi T, Arbel R et al. · 2026 · Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases
Objective To evaluate the diagnostic performance of BioPlex 2200 multiplex immunoassay (BI) for detecting antinuclear antibodies (ANA), compared with the gold standard, the indirect immunofluorescence assay (IIF), as a screening…
View details →Tri PM, Hung NT, Liet DH et al. · 2026 · Emergency radiology
Purpose To assess the diagnostic performance of computed tomography (CT) for predicting main pancreatic duct injury in surgically explored patients with distal pancreatic trauma. Methods We conducted a prospective single-center diagnostic…
View details →Wei XT, Zhu LY, Wu YL et al. · 2026 · Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi
Objective: To evaluate the screening performance and related factors of ultrasound for hepatic steatosis in community-based elderly populations using controlled attenuation parameter (CAP) measured by transient elastography as the…
View details →TEZCE A, DURMUŞ E · 2026 · Preprint
Abstract Purpose The objective of this study is to compare the diagnostic efficacy of Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) in detecting lumbar spondylolysis among patients presenting with chronic low back pain, and…
View details →Livorsi DJ, Ritter S, Lund BC et al. · 2026 · Preprint
Abstract Background: The pneumococcal urinary antigen test can help rapidly identify Streptococcus pneumoniae as the cause of community-acquired pneumonia (CAP). In this study, we assessed the utility of this test across an integrated…
View details →Zorlutuna Kaymak N, Pekel İ, Demir Tekol S et al. · 2026 · BMC ophthalmology
Purpose To evaluate the diagnostic utility and real-world clinical impact of polymerase chain reaction (PCR) analysis of aqueous humor (AH) and vitreous samples in patients with uveitis including suspected infectious and mixed…
View details →Genetic And Metabolic Disorders Screening Subgroup Of The Birth Defects Prevention And Control Committee Chinese Preventive Medicine Association, Rare Diseases Branch Of Shandong Medical Association, Genetic Metabolism Branch Of Shandong Provincial Rare Disease Association et al. · 2026 · Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics
High-throughput sequencing technology has recently been used in neonatal disease screening. To address the issues related to the screening process, interpretation of screening results, and recall of positive cases in neonatal genetic…
View details →Inácio ML, Rusinque L, Nóbrega F et al. · 2026 · Plant disease
Aphelenchoides besseyi , the causal agent of the white-tip disease, is a quarantine nematode known to affect rice ( Oryza sativa ) by colonizing leaf tips and panicles. In January 2021, A. besseyi was detected in Portugal in imported…
View details →Goren T, Vashdi DR, Beeri I · 2026 · Social science & medicine (1982)
Political trust is considered crucial for enhancing civic compliance with government policies and instructions, particularly during a health crisis. However, evidence from the COVID-19 pandemic, a major global health crisis, suggest a more…
View details →Mohanta S, Tye KM · 2025 · Neuron
In this issue of Neuron, Biane et al. 1 used cellular-resolution recordings in ventral CA1 (vCA1) to comprehensively establish that it encodes stimulus features and identity, but not a generalized abstraction of valence. This suggests a…
View details →Zhou G, Dael N, Verweij S et al. · 2026 · Pharmaceuticals (Basel, Switzerland)
Background: The rapid emergence of immune-evasive SARS-CoV-2 variants necessitates the identification of accessible, low-cost prophylactic strategies. While drug repurposing offers a time-efficient alternative to novel drug development,…
View details →Brent DA · 2026 · Journal of the American Academy of Child and Adolescent Psychiatry
In this issue of JAACAP, Asarnow and colleagues report the results of their innovative, elegantly conducted clinical trial that assessed the added value of stratified, stepped care (SSC) for youth at risk for suicidal behavior in a health…
View details →Haroon A, Almuhaideb A, Adeleke S et al. · 2026 · Nuclear medicine communications
Objective To assess the accuracy of 18F choline PET/magnetic resonance (MR) when compared with the reference standard MRI-guided template mapping (TPM) biopsies for evaluation of biochemical relapse of prostate cancer in patients with…
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