19,879 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Ringer AJ, Hanel RA, Baig AA et al. · 2025 · Journal of neurointerventional surgery
Background The optimal duration for dual antiplatelet therapy (DAPT) after stent-assisted coiling (SAC) of intracranial aneurysms is unclear. Longer-term therapy may reduce thrombotic complications but increase the risk of bleeding…
View details →Bierer JD, Stanzel R, Henderson M et al. · 2026 · The Annals of thoracic surgery
Background Pediatric cardiac surgery with cardiopulmonary bypass (CPB) is associated with systemic inflammation. This trial aimed to determine whether continuous high-exchange ultrafiltration during CPB has a clinical immunomodulatory…
View details →Khueangchiangkhwang S, Oida Y, Taguchi A et al. · 2026 · Parasitology international
Trichinella is a nematode that causes chronic infection via its larvae in muscle cells and remains a global health concern. Drug sensitivity, including to ivermectin (IVM), differs between intestinal adult worms (AW) and muscle larvae…
View details →Dunkel K, Moroz MS, Suares B et al. · 2025 · The Journal of dairy research
This research article aimed to evaluate the effect of a commercial nutraceutical additive in milk replacer on the health and weight gain of dairy calves during the pre-weaning phase. A total of 126 female Holstein calves were randomly…
View details →Meves V, Chamieh A, Mohamed M et al. · 2026 · Endoscopy international open
Background and study aims Previous studies in esophagogastroduodenoscopy or colonoscopy have demonstrated positive effects of music on patient anxiety and comfort. This study prospectively evaluated the effect of functional music on…
View details →Kashtiara A, Pauptit J, Thijs D et al. · 2025 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Objectives Enhanced Recovery After Surgery (ERAS) protocols aim to improve surgical outcomes, by mitigating postoperative stress through multimodal perioperative care. In spinal surgery, such protocols may reduce pain, hospital length of…
View details →Sielski W, Osęka T, Antolak A et al. · 2026 · Frontiers in endocrinology
Background Parathyroid preservation during total thyroidectomy with central neck dissection in papillary thyroid carcinoma remains challenging due to the glands' delicate vascular anatomy and risk of inadvertent devascularization or…
View details →Palmier M, Ghorayeb G, Arhant G et al. · 2026 · Annals of vascular surgery
Background Supraceliac aortic cross-clamping can induce remote organ injury, particularly affecting the lungs through ischemia-reperfusion mechanisms. Pulmonary endothelial dysfunction plays a central role in acute lung injury, potentially…
View details →García-García M, Mosqueda J, Escobar Cabrera JE et al. · 2025 · Toxicon
A recent clinical case involving a Poecilotheria regalis bite was treated with Mexican L. mactans antivenom (Aracmyn Plus, Silanes, Mexico), resulting in the improvement of some of the symptoms. This could be attributed to cross-reactivity…
View details →Hooshiar MH · 2026 · The Journal of prosthetic dentistry
Statement of problem Artificial intelligence (AI) language models have been increasingly used for clinical decision-making in implant dentistry and for scholarly writing. Yet, their reliability, fabrication rates, and comparative…
View details →Tsakmaki PV, Tasoulis S, Georgakopoulos SV et al. · 2025 · International journal of neural systems
This research looks at the use of long-short-term memory (LSTM) networks to predict psychosis, in patients within the schizophrenia spectrum, based on Heart Rate Variability (HRV) data acquired from wearable devices. Our primary objective…
View details →Szabó D, Tóth A, Nagy CB et al. · 2025 · Orvosi hetilap
Introduction The glomus caroticum, located at the carotid bifurcation, contains chemoreceptors and is essential for the rapid physiological adaptation to changes in blood oxygen, carbon dioxide, and pH levels. Paragangliomas of the glomus…
View details →Sanak F, Iselin K, Kaufmann C et al. · 2026 · Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
Purpose To analyze the effect of fasting on volume, growth factor, and lipid concentration in eye drops derived from autologous serum (AS) and leukocyte-poor platelet-rich plasma (LP-PRP). To assess changes in protein and growth factor…
View details →Hughes C, Myers MA, Tickell-Painter M et al. · 2026 · Clinical biochemistry
Introduction The climate crisis is a health crisis, and healthcare contributes to this via consumption of resources, the release of greenhouse gases, and the generation of waste. Pathology testing underpins most healthcare, and the vast…
View details →Regev-Yochay G, Barda N, Shusterman Y et al. · 2026 · NEJM evidence
Background In 2024, Israel faced a major West Nile virus (WNV) disease outbreak. We aimed to evaluate the efficacy and safety of WNV-neutralizing plasma for hospitalized patients with WNV disease. Methods We conducted a randomized,…
View details →Tavolinejad H, Bozorgi A, Emkanjoo Z et al. · 2025 · Journal of the American College of Cardiology
Background Vasovagal syncope (VVS) is a common yet challenging condition with limited effective treatments. Elastic compression stockings (ECS) have been proposed as a potential therapy, but their real-world effectiveness remains unclear.…
View details →Zhang F, Yu Z, Pan J et al. · 2026 · Jornal de pediatria
Objective This study aimed to investigate the risk factors for acute neurological complications (ANCs) in neonates with bacterial meningitis (NBM). Methods This retrospective study analyzed 68 neonates (aged 0-28 days) with bacterial…
View details →Sanchis J, Bueno H, Martí Sánchez D et al. · 2025 · Heart (British Cardiac Society)
Background Clinical trials and meta-analyses indicate a reduced reinfarction risk with invasive management in older patients with non-ST-segment elevation myocardial infarction (NSTEMI). This study investigated whether similar benefits…
View details →Qiao W, Liu L, Zhang X et al. · 2024 · Preprint
Abstract Background Subarachnoid anesthesia is the primary anesthetic method for elective cesarean section surgery, characterized by rapidly taking effect and reliable analgesia. However, subarachnoid anesthesia is prone to cause a high…
View details →Kashtiara A, Pauptit J, Thijs D et al. · 2025 · Preprint
Abstract BACKGROUND AND OBJECTIVES: Enhanced Recovery After Surgery (ERAS) protocols aim to improve surgical outcomes, by mitigating postoperative stress through multimodal perioperative care. In spinal surgery, such protocols—termed…
View details →Muir KJ, Maye A, McHugh MD et al. · 2025 · JAMA network open
Importance It is unknown if virtual nursing (VN) enhances care quality or improves the workload of bedside nurses in hospitals. Objective To describe what services VNs provide to patients and nurses in hospitals; to evaluate whether the…
View details →Zhang J, Suo T, Cheng Y et al. · 2026 · Journal of investigative medicine : the official publication of the American Federation for Clinical Research
Hemophagocytic lymphohistiocytosis (HLH) secondary to visceral leishmaniasis (VL-HLH) is a severe and often fatal condition marked by systemic inflammation and immune dysfunction. In this retrospective cohort study at Shanxi Children's…
View details →Smedemark SA, Jarbøl DE, Laursen CB et al. · 2026 · The lancet. Healthy longevity
Background Diagnosing acute respiratory conditions in adults older than 65 years is challenging due to age-related physiological changes, which increase diagnostic complexity and the risk of hospital admission. We investigated whether…
View details →Nakamura Y, Murata S, Yabe T et al. · 2026 · Cureus
Introduction C5 palsy is a disabling complication after posterior cervical decompression and fusion (PCDF). Whether C4/5 facetectomy reduces the incidence or improves the outcomes of C5 palsy remains uncertain. Therefore, this study aimed…
View details →Santos CMM, Mattos NM, Silva RAP et al. · 2025 · Lasers in medical science
This pilot study aimed to investigate the effects of intravascular laser irradiation of blood (ILIB) on anxiety levels and vital signs in patients undergoing third molar extraction. A randomized, placebo-controlled clinical trial was…
View details →Zhan J, Sun G, Li H et al. · 2026 · Ophthalmology. Retina
Objective To evaluate whether timing of preoperative anti-VEGF therapy given before vitrectomy for proliferative diabetic retinopathy (PDR) influences risks of postoperative vitreous hemorrhage (VH) and tractional retinal detachment (TRD).…
View details →Holland K, Gomeniouk O, Owen GS et al. · 2026 · European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Purpose Determine if there is a difference in post-operative infection rates in patients undergoing sialendoscopy who received pre-, post-operative, both pre and post, or no antibiotics. Methods Retrospective chart review of patients who…
View details →Kipper CW, Kis P, Burleson KN et al. · 2026 · European journal of applied physiology
Objective Exercise-induced muscle damage (EIMD) compromises neuromuscular function and reduces exercise tolerance. Whether muscle oxidative capacity (MOC), an index of mitochondrial function, is reduced by EIMD or influences neuromuscular…
View details →Valle-Cruz JA, Lopiz Y, Garríguez-Pérez D et al. · 2026 · International orthopaedics
Purpose Rotational instability is a key factor in fixation failure of extracapsular hip fractures. The U-Blade (RC) lag screw was designed to improve rotational stability. This study aimed to compare mechanical complication rates between…
View details →Sujan M, Skarstad H, Rosvold G et al. · 2025 · Preprint
Objectives Gestational diabetes mellitus (GDM), particularly when combined with overweight or obesity, is associated with adverse neonatal outcomes such as high birth weight and increased adiposity. We determined the effect of a…
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