e-ISSN: Pending

Browse the failure-mode index

19,879 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen access

Comparative evaluation of photoactivated disinfection and sonic irrigation as an adjunct to conventional irrigation on Enterococcus faecalis in root canals: An in vitro study

Tushar Kohli, N. Mehta, G. Garima et al. · 2021

Objective: The aim of the in vitro study was to compare the antibacterial efficacy of photoactivated disinfection (PAD), sonic irrigation as an adjunct to conventional irrigation against Enterococcus faecalis in vitro. Materials and…

View details →
Negative / Null Result ReportMedicine

Interplay Among Reward Processing, Schizotypal Traits, and Psychosocial Stress in a Large Chinese Young Adult Sample: A Cross‐Sectional Network Analysis

Donghao Tuo, Yi-hang Huang, Simon S. Y. Liu et al. · 2026 · PsyCh Journal

ABSTRACT Reward processing comprises reward sensitivity, motivation, and pleasure experience, but how these components jointly relate to schizotypal traits and psychosocial stress in young adult samples remains unclear. Using network…

View details →
Negative / Null Result ReportMedicine

Glutathione S-transferase expression in benign and malignant eyelid tumors

Efe Saygın, R. Karadag, S. Ozkanlı et al. · 2021 · Biotechnic & Histochemistry

ABSTRACT Eyelid tumors commonly originate from the skin and its appendages. Environmental toxins and oxidants affect eyelid carcinogenesis. Glutathione S-transferases (GST) are antioxidants that participate in pathogenesis. We investigated…

View details →
Negative / Null Result ReportOpen accessMedicine

Vaccination counseling with and without excipient skin testing in patients with suspected allergic reactions to mRNA COVID-19 vaccines and patients with atopy

Dilawar Khokhar, K. O’Shea, C. Akin et al. · 2022 · Journal of Allergy and Clinical Immunology: Global

Background Allergic reactions have been reported with mRNA vaccines for COVID-19 prevention. Patients perceived to be at higher risk for a reaction may be referred to an allergist, although evaluation strategies may differ between…

View details →
Negative / Null Result ReportMedicine

Exploratory safety investigations in normal, freely moving Göttingen minipigs using telemetry: Pharmacological validation.

Julie Jacobsen, Berit Ø. Christoffersen · 2025 · Journal of pharmacological and toxicological methods

INTRODUCTION Adverse cardiovascular (CV) effects is a major cause of drug attrition. Early assessment of CV risk for new drug candidates may be warranted for early de-risking of the further development. Predictive animal models and a…

View details →
Negative / Null Result ReportOpen accessMedicine

Evaluation of Health Literacy and Associated Factors Among Adults Living in Saudi Arabia: A Cross-Sectional Study

Yaser M. Alahmadi · 2023 · Inquiry : a journal of medical care organization, provision and financing

In this westernized culture, maintaining a healthy lifestyle has become a major health concern internationally. Health literacy is an emerging concept and requires effective measures and reform to improve the health status and health of…

View details →
Negative / Null Result ReportMedicine

PP27 Pre-hospital lactate monitoring: a worthy adjunct to systolic blood pressure and shock index in triggering blood product administration in patients with suspected traumatic haemorrhage?

J. Griggs, M. Sherriff, J. Leung et al. · 2019 · Emergency Medicine Journal

Introduction Pre-hospital identification of patients with suspected occult traumatic haemorrhage is problematic. Physiological parameters and clinical gestalt are inadequate surrogates for ongoing haemorrhage. Lactate monitoring may hold…

View details →
Negative / Null Result ReportMedicine

AAV2-hCHM Subretinal Delivery to the Macula in Choroideremia: Two Year Interim Results of an Ongoing Phase I/II Gene Therapy Trial.

T. Aleman, Rachel M. Huckfeldt, Leona W. Serrano et al. · 2022 · Ophthalmology (Rochester, Minn.)

PURPOSE To assess the safety of the subretinal delivery of a recombinant adeno-associated virus serotype 2 (AAV2) vector carrying a human CHM-encoding cDNA in choroideremia (CHM). DESIGN Prospective, open-label, non-randomized,…

View details →
Negative / Null Result Report

Production of recombinant pepsin, pancreatic lipase and colipase from Pichia pastoris as feed additive

F. Liu · 2014 · Recent progress in swine breeding and raising technologies and cutting-edge reproductive technologies and perspectives for their usage in swine

Enzyme feed additives are always added in animal nutrition to improve the quality of feeds, or to improve the animals’ growth performance and health through intensifying digestibility of the feed ingredients. This study investigated the…

View details →
Negative / Null Result Report

MODERASI KEBIJAKSANAAN DALAM HUBUNGAN IDENTITAS DIGITAL DAN PERBANDINGAN SOSIAL PADA GENERASI Z PENGGUNA LINKEDIN

Riana Sahrani, Cherry Delfina Setiawan, Callista Chandra et al. · 2026 · CENDEKIA: Jurnal Ilmu Pengetahuan

ABSTRACT Digital identity is a self-representation built through online activities and has become a crucial aspect for Generation Z, who grew up amidst technological advancements. One widely used platform is LinkedIn, which functions not…

View details →
Negative / Null Result ReportOpen accessMedicine

Assessing the Safety of Craniotomy for Resection of Primary Central Nervous System Lymphoma: A Nationwide Inpatient Sample Analysis

Jonathan Yun, Jingyan Yang, Michael Cloney et al. · 2017 · Frontiers in Neurology

Background Unlike many other central nervous system (CNS) tumors, the surgical management of primary central nervous system lymphomas (PCNSL) is traditionally limited by diagnostic biopsy. Studies that predate the use of modern…

View details →
Negative / Null Result ReportOpen accessMedicine

Is the use of BITA vs SITA grafting safe and beneficial in octogenarians?

D. Pevni, T. Ziv-Baran, A. Kramer et al. · 2020 · Annals of Thoracic Surgery

BACKGROUND Bilateral internal thoracic artery grafts (BITA) is questionable in octogenarians because of shorter life expectancy and increased risk of perioperative complications. The aim of this study was to examine the safety and…

View details →
Negative / Null Result ReportOpen accessMedicine

Atlantooccipital overlapping and its effect on outcomes after ventral fixation in dogs with atlantoaxial instability

F. Takahashi, Takaharu Hakozaki, Shigenori Kouno et al. · 2018 · Journal of Veterinary Medical Science

We compared clinical outcomes after ventral fixation in dogs with atlantoaxial instability (AAI) on the basis of the presence or absence of atlantooccipital overlapping (AOO). Of 41 dogs diagnosed with AAI and treated ventral fixation, 12…

View details →