Negative / Null Result ReportOpen accessDentistry
Merna M. Seif, Ahmed A. Abdel Hakim, Hassan M. Abouelkheir et al. · 2025 · BMC Oral Health
Abstract Background Accurate impression registration is essential for transferring the three-dimensional (3D) implant position to the definitive cast, ensuring passivity of the final prosthesis. Various impression techniques have been developed to optimize accuracy, particularly for angulated implants. This study aimed to evaluate and compare the accuracy of open-tray impression copings, clips impression copings, and hexed implant mounts in transferring implant positions for both straight and angulated implants. Methods Five implants with different angulations (three at 0°, one at 15°, and one
View details →Negative / Null Result ReportOpen accessMedicine
Laura Emanuelle da Rosa Carlos Monteiro, Sheila Piccoli Garcia, Leonardo Grabinski Bottino et al. · 2022 · Archives of Endocrinology and Metabolism
ABSTRACT Objective: To evaluate the precipitating factors of diabetic ketoacidosis (DKA) in patients with type 1 diabetes hospitalized through the emergency department of a tertiary hospital. Materials and methods: Individuals with type 1 diabetes hospitalized for DKA from January 2005 to March 2010 (first period [P1], n = 75) and from April 2010 to January 2017 (second period [P2], n = 97) were identified through a query of electronic medical records. Data were collected by reviewing medical records. Only the first hospitalization of each participant in each period was included. Results: In P
View details →Negative / Null Result Report
Xiang Zheng, Yingying He, Minmin Cao et al. · 2025 · Canadian Journal of Forest Research
Chinese fir ( Cunninghamia lanceolata (Lamb.) Hook) is one of the most dominant tree species in southern China. However, the effect of different nitrogen (N) levels on soil respiration in subtropical Chinese fir plantations remains…
View details →Negative / Null Result ReportOpen accessSports medicine
Mario Hevesi MD, PhD, Alexander M. Boos, Allen Wang et al. · 2024 · Orthopaedic Journal of Sports Medicine
Objectives: Medial meniscus posterior root tears (MMPRTs) render the meniscus essentially non-functional, resulting in increased peak contact pressures, reduced forced dissipation, and increased risk of early osteoarthritis. Transtibial root repair has shown promise at restoring meniscus function and improving clinical outcomes; however, a paucity of literature exists evaluating the prognostic clinical and radiographic factors for poor outcomes following isolated meniscus root repair. The purpose of this study was to 1) describe the patient reported clinical outcomes after isolated MMPRT repai
View details →Negative / Null Result ReportOpen accessMedicine
Matthias Huber, Till Treutler, Peter Martus et al. · 2013 · PLoS ONE
Unlabelled Treatment of hypertension in hemodialysis (HD) patients is characterised by lack of evidence for both the blood pressure (BP) target goal and the recommended drug class to use. Telmisartan, an Angiotensin receptor blocker (ARB) that is metabolised in the liver and not excreted via HD extracorporeal circuit might be particularly suitable for HD patients. We designed and conducted a randomised, placebo-controlled, double-blind and cross-over trial for treatment of dialysis-associated hypertension with telmisartan 80 mg once daily or placebo on top of standard antihypertensive treatmen
View details →Negative / Null Result ReportOpen accessOrthopedic surgery
Taeko Fukuda, Shinobu Imai, Shunji Simoda et al. · 2020 · Journal of Orthopaedic Surgery
Purpose: It is unclear whether perioperative analgesic techniques affect the functional outcome of total knee replacement (TKR). We investigated the effects of peripheral nerve block (PNB) and local infiltration (LI) on walking ability after TKR. Methods: The medical records of 7143 patients who underwent TKR using general anesthesia with PNB or LI techniques were reviewed. Factors affecting independence and/or improvement of walking after surgery were investigated using multivariate regression analysis. To adjust for baseline differences and minimize selection bias for the chosen analgesic te
View details →Negative / Null Result ReportOpen accessMedicine
Thaiz Ferraz Borin, Debora A P C Zuccari, Bruna V Jardim-Perassi et al. · 2014 · PLoS ONE
A selective inhibitor of 20-HETE synthesis, HET0016, has been reported to inhibit angiogenesis. 20-HETE has been known as a second mitogenic messenger of angiogenesis inducing growth factors. HET0016 effects were analyzed on MDA-MB-231 derived breast cancer in mouse and in vitro cell line. MDA-MB-231 tumor cells were implanted in animals' right flank and randomly assigned to early (1 and 2), starting treatments on day 0, or delayed groups (3 and 4) on day 8 after implantation of tumor. Animals received HET0016 (10 mg/kg) treatment via intraperitoneal injection for 5 days/week for either 3 or 4
View details →Negative / Null Result ReportOpen accessNursing
Tarek Mahmoud Shaker Mohamed, Hala Mohamed Abdelhamed Ali, Asmaa Sayed Abd-Almageed et al. · 2022 · International Egyptian Journal of Nursing Sciences and Research
Background: COVID-19 represents a major threat to hemodialysis health life, due to their low immunity, it is essential to wear a face mask to protect them against the outbreak of the COVID-19 pandemic. Aim: To evaluate the effect of wearing a face mask on oxygen saturation among hemodialysis patients versus healthy staff members.Methods: Research design: a quasi-experimental research design Setting: dialysis units at Mansoura University and New General Mansoura hospital. Subjects: A purposive sample with a total of 190 patients was classified into two equal groups, entitled hemodialysis patien
View details →Negative / Null Result ReportOpen accessSports medicine
Nurtekin Erkmen, Yağmur Kocaoğlu, Ahmet Kaan Aslan et al. · 2023 · Türk Spor ve Egzersiz Dergisi
The aim of this study was to investigate the effect of warm-up activity on the visual response time of the dominant and non-dominant hand and foot in basketball players. A total of 13 male basketball athletes with an age of 14.38 ± .506 years, height 180.15 ± 8.07 cm, body weight 66.54 ± 13.73 and sports experience 4.69 ± 13.73 years were voluntarily included in the study. Visual response time of the dominant and non-dominant hand and foot were measured before and after the warm-up protocol. The warm-up protocol consisted of a 20-minute warm-up activity including basketball-specific movements
View details →Negative / Null Result ReportOpen accessOphthalmology
Shunsuke Nakakura, Ryo Asaoka · 2022 · Eye and Vision
Abstract Background To evaluate the postoperative outcomes of initial trabeculectomy (Trab) and Ex-PRESS (EX) in terms of achieving an intraocular pressure (IOP) below 15 and 18 mmHg. Methods This study retrospectively analyzed 64 and 54 cases of Trab and EX, respectively, performed by the same surgeon with uniform management from April 2018 to March 2019. Surgical success was defined as 5 < IOP < 15 mmHg (criterion 1) and 5 < IOP < 18 mmHg (criterion 2) without additional glaucoma medication, needling, and bleb reconstruction 2 months after surgery. Survival analysis with Cox regression was p
View details →Negative / Null Result ReportOpen accessMedicine (General)
Yuli Lusiana Sari, Desi Dwi Wisudanti, Muhammad Ali Shodikin · 2018 · Journal of Agromedicine and Medical Sciences (AMS)
Cocoa (Theobroma cacao L) is an industrial material that often used in chocolates production, but the part that used is cocoa bean, so that cocoa husk accumulate as waste. This study aimed to determine effectiveness of cocoa husk extracts to first and second phase of licking time of mice induced formalin. This study used 28 mices that divided into seven groups. NaCMC 1% to group K(-), 0.0048 mg/gBW sodium diclofenac to K(+), extracts dose variations, ie 0.25 mg/gBW, 0.5 mg/gBW, 1 mg/gBW, 2mg/gBW and 4 mg/gBW to group K1, K2, K3, K4, and K5 administered orally 30 minutes before subcutaneous inj
View details →Negative / Null Result ReportOpen accessOrthopedic surgery
Akhil A. Chandra, Filippo Romanelli, Alex Tang et al. · 2022 · Knee Surgery & Related Research
Abstract Background Flap reconstruction with perforator, fasciocutaneous, muscular, and/or free microvascular flaps is utilized to cover wound defects and improve vascularization and antibiotic/nutrient delivery. Flap use in revision procedures for total knee arthroplasty has been explored previously; however, current data are limited and studies comparing healing and complication rates between different flap types are lacking. Methods A literature review was performed using PubMed on 13 January 2022. Studies were included if they reported healing and complication rates for either gastrocnemiu
View details →Negative / Null Result ReportOpen accessMedical technology
Carlo Calabrese, Carlo Calabrese, Dania Gelli et al. · 2022 · Frontiers in Medical Technology
BackgroundCrohn's disease (CD) is a potentially debilitating condition that burdens Italian healthcare substantially. The symptomatic management relies on prompt therapy adjustment to reduce flares and follow-up diagnostic inputs to maximise remission. Capsule endoscopy (CE) has introduced advantages in CD diagnostics, allowing the direct inspection of the entire gastrointestinal mucosa. The diagnostic procedure is comparable in effort to standard ileocolonoscopy (IC) but requires no anaesthesia. Whether CE follow-up improves clinical outcomes remains to be defined.ObjectivesTo provide a preli
View details →Negative / Null Result ReportOpen accessNeurology. Diseases of the nervous system
Yuan-yuan LU, Xu-tong ZHAO, Qing-qing WANG et al. · 2018 · Chinese Journal of Contemporary Neurology and Neurosurgery
Objective To investigate the mitochondrial DNA (mtDNA) mutation load in hair follicles from different scalp regions of patients with mitochondrial, encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS), compare the mutation load in different scalp regions, and analyze the difference in mutation load between scalp regions with lesion site in the brain and scalp regions without lesion site in the brain. Methods Seven MELAS patients with m.3243A > G mutations were studied. Hair follicles were obtained from 8 scalp regions (bilateral frontal, temporal, parietal and occipital lobe
View details →Negative / Null Result ReportOpen accessDentistry
Anum Tanwir, Shahbaz Ahmed, Hira Akhtar et al. · 2022 · European Endodontic Journal
Objective: The objective of this study was to compare the effectiveness of premedication drugs including single dose Piroxicam and Prednisolone in regard to post endodontic pain at different time intervals (24, 48, 72 and 96 hours) after single visit root canal treatment. Methods: This randomized clinical trial (registration no. NCT04124822) was performed in operative dentistry department of a private clinical institute. One hundred twenty patients identified with symptomatic irreversible pulpitis were included in the study. The pain intensity levels were marked through the use of visual analo
View details →Negative / Null Result ReportOpen accessMedicine
Wishyar Jamal Al-Bazzaz, Nihad Rifaat Jawad2 Ali W. AlKhayat · 2020 · Zanco Journal of Medical Sciences
Background and objective: Prostate Thulium laser vaporization is a novel treatment option for a bladder outlet obstruction caused by benign prostate enlargement. However, this surgical technique has not yet been standardized. We present our finding of using Tm vaporesection of the prostate. This study aimed to assess the efficacy and safety of thulium laser versus bipolar transurethral resection of the prostate for treating patients with benign prostatic obstruction. Methods: Sixty three consecutive patients with benign prostatic hyperplasia attending public and private clinics in Erbil city w
View details →Negative / Null Result ReportOpen accessSocial Sciences
Richie Bayuran · 2019 · JPAIR
Brown seaweed is one of the algal species that has been used as food, a source of nutritional supplements, and formulated for therapeutic and cosmetic purposes. This study evaluated the antioxidant and antistaphylococcal activities of topical fucoidan gel (TFG) from the Sargassum oligocystum. A completely randomized design was used, and the experimental protocol includes extraction, lyophilization, and characterization, quality testing, and biological assay. Physicochemical tests suggested that the lyophilized fucoidan is comparable with the properties of pharmaceutical-grade fucoidan. FTIR ch
View details →Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Cristiana Mateus, Cláudio J. Maia, Fernanda Domingues et al. · 2023 · Antibiotics
Aliarcobacter butzleri is a Gram-negative bacterium associated with infections of the gastrointestinal tract and widely distributed in various environments. For successful infection, A. butzleri should be able to tolerate various stresses during gastrointestinal passage, such as bile. Bile represents an antimicrobial host barrier that acts against external noxious agents and consists of a variety of bile salts. The intestinal bile salts act as detergents involved in the antimicrobial host defense; although, on the bacterial side, they could also serve as a signal to activate virulence mechanis
View details →Negative / Null Result ReportOpen accessAgriculture
Ana Guiomar Matos Santiago Reis, Raquel Yvonne Arantes Baccarin · 2010 · Ciência Rural
Twenty Thoroughbred racehorses were ultrasonographically evaluated to determine the relation between normal values of the cross-sectional area (CSA) of the right and left forelimbs superficial digital flexor tendons (SDFT) in the metacarpal region for trained and untrained Thoroughbreds racehorses. Ultrasonography revealed that CSA at 26cm distal to the accessory carpal bone is larger than other proximal levels, for either left or right forelimbs. In addition, the CSA at 2, 4, 6, 8, 10, 12 and 14cm distal to the accessory carpal bone of the left forelimb are larger (P 0.05) between left and ri
View details →Negative / Null Result ReportOpen accessSurgery
Yoshihiro Sakai, Shunsuke Kasai, Akio Shiomi et al. · 2026 · Annals of Gastroenterological Surgery
ABSTRACT Aim Few reports have described pelvic reinforcement procedure (PRP) to prevent perineal hernia (PH) in robotic abdominoperineal resection (Ro‐APR) for rectal cancer. This study aimed to investigate the safety and efficacy of PRP in Ro‐APR. Methods Patients who underwent Ro‐APR for rectal cancer between January 2020 and June 2023 were retrospectively examined. PRP was performed as a prophylactic procedure for PH. Four types of PRP were performed depending on the case (closure of the levator ani muscles, the pelvic peritoneum with the uterus, the pelvic peritoneum, and the pelvic perito
View details →Negative / Null Result ReportOpen accessMedicine (General)
Thuy Thi-Thanh Tran, Huy Phuong Tran, Loc Thai Ly et al. · 2024 · Middle East Fertility Society Journal
Abstract Background Endometrial preparation significantly influences the success of embryo transfer procedures. Although both oral and transdermal estradiol are common methods for endometrial priming, their efficacy and potential side effects remain uncertain. This randomized controlled trial aims to compare the effectiveness of oral and transdermal estradiol in endometrial preparation, while also evaluating their respective side effects in patients undergoing assisted reproduction treatments. Method This randomized clinical trial (ISRCTN15301227) was conducted at Hung Vuong Hospital between J
View details →Negative / Null Result ReportOpen accessMedicine
Elham Naghshineh, Safoura Rouholamin, Zahra Derakhshandeh · 2023 · Advanced Biomedical Research
Background: Asherman syndrome is a controversial issue in obstetrics and gynecology without any consensus on its management and treatment. It is characterized by variable lesions inside the uterine cavity and also causes menstrual irregularities, infertility, and placental abnormalities. The study aimed to assess the platelet-rich plasma (PRP) effect in women with intrauterine adhesions by evaluating the improvement of the menstrual cycle and intrauterine adhesion (IUA) stage. Materials and Methods: This clinical trial study was performed on 60 women with Asherman syndrome in two groups of 30.
View details →Negative / Null Result Report
J Vietheer, C Unbehaun, K Classen et al. · 2019 · European Heart Journal
Abstract Background Graft failure caused by allograft rejection and vasculopathy is the most common cause of mortality after heart transplantation. To detect an early allograft rejection, endomyocardial biopsy is still needed. Tissue…
View details →Negative / Null Result Report
Cassandra Campbell, Kristin Wyckoff, Ronak Naik et al. · 2025 · Pediatric Cardiology
Abstract We sought to determine the impact of the COVID-19 on prenatal diagnosis (PND) of clinically significant congenital heart disease (CHD) and the role of socioeconomic status (SES), complexity of diagnosis, and proximity to advance…
View details →Negative / Null Result Report
Fernando Medrano, Benjamín Gallardo, Pablo Gutiérrez et al. · 2024 · Marine Ornithology
The impact of the El Niño varies across seabirds, usually altering the distribution and causing population declines. Understanding El Niño’s effects is thus critical for conservation. We monitored 296 nests of the little-known Hydrobates…
View details →Negative / Null Result ReportOpen access
Greenwood, Brian M, Walley, AJ, Greenwood, BM et al. · 2002
The influence of haptoglobin polymorphisms on severe malaria occurrence was assessed in 1183 individuals from The Gambia. No significant association was found between severe malaria and either haptoglobin genotypes or phenotypes. The…
View details →Negative / Null Result ReportOpen access
Willy Sandhika, Faroek Hoesin, Dyah Fauziah · 2020
No significant correlation was found between c-erbB2 expression and tumor size (T-stage). c-erbB2 expression in various N-stages were as follows: N0 (80%), N1 (33,3%), N2 (50%), N3 (42,9%). No significant correlation was found between…
View details →Negative / Null Result ReportOpen access
Wynands, Seth · 2015
This paper examines the socio-political instability link between inequality and investment. For the period between 1960 and 2011 for 192 countries, this paper finds no significant correlation between inequality and instability and no…
View details →Negative / Null Result ReportOpen access
Schneider, Josephine · 2020
The present study showed that there is a significant difference in the functional connectivity in some connections between schizophrenic patients and healthy controls. There is no significant correlation between the functional connectivity…
View details →Negative / Null Result ReportOpen access
Igwe, Nwobueze olru · 2023
This paper tried to examine correlation with different imaging techniques and aortic stenosis severity. There was no significant correlation found between the diastolic AVA area and AR, although a positive tendency was observed between the…
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