20,240 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
I. Jug, D. Jug, M. Sabo et al. · 2011 · Turkish Journal of Agriculture and Forestry Sciences
Eight different soil tillage systems (TS) for winter wheat after soybean crop production were compared at the chernozem soil type in Croatian Baranya region in a 4-year period (2001/2002, 2002/2003, 2003/2004, 2004/2005). Tillage systems…
View details →Margaret Diana , Deviana Soraya Riu, Fatmawati Madya et al. · 2025 · Obgynia
Objective: This study aimed to investigate the impact of SHS exposure on fetal biometry and umbilical artery flow at 24 – 28 weeks of gestation. Methods: This cross-sectional study included 110 pregnant women, divided into a study group (55 passive) smokers and a control group (55 non-passive smokers). Serum cotinine levels were measured using ELISA. Fetal biometry (biparietal diameter, head circumference, abdominal circumference, and femur length) and umbilical artery flow (pulsatility and resistance indices) were assessed via ultrasound and Doppler ultrasonography. Group comparisons were con
View details →Souvik Sardar, Somenath Sarkar, Indrashis Podder et al. · 2022 · Indian Journal of Dermatology
Background: Primary scarring alopecias (PSAs) are a rare group of dermatological disorders with overlapping clinical features. They result in permanent hair loss and significant psychological morbidity. Aims: To analyze the clinico-epidemiology of PSAs of the scalp, along with clinico-pathological correlation. Methods: We conducted a cross sectional, observational study including 53 histopathologically confirmed cases of PSA. Clinico-demographic parameters, hair care practices, and histologic characteristics were noted and statistically analyzed. Results: Among 53 patients (mean age 30.9 ± 8.1
View details →Brajušković G., Nikolić Zorana, Kojić A. et al. · 2013 · Archives of Biological Sciences
Prostate cancer (PCa) is the second most commonly diagnosed cancer among men worldwide. Despite its high incidence rate, the molecular basis of PCa onset and its progression remains little understood. Genome-wide association studies (GWAS) have greatly contributed to the identification of single nucleotide polymorphisms (SNP) associated with PCa risk. Several GWAS identified 8q24 as one of the most significant PCa-associated regions. The aim of this study was to evaluate the association of SNP rs378854 at 8q24 with PCa risk in the Serbian population. The study population included 261 individua
View details →Nissar Shaikh, Huda Al Mahdi, Anant Pai et al. · 2022 · Annals of Medicine
Introduction COVID-19 patients presenting with ocular manifestations are from 0.8% to 32% of patients seen in the ED. The available literature is scarce regarding COVID-19 patients presenting with ocular manifestations from the Middle Eastern region. Purpose This study aims to report the incidence of ocular signs and symptoms in COVID-19 patients and find any correlation between the occurrence of ocular manifestations and patients’ comorbidities. Methods All patients having the primary diagnosis of COVID-19 infection and concurrent ocular manifestations on admission to our tertiary COVID-19 he
View details →Kiho Sung, Junsol Kim, Yeong-Ran Park et al. · 2026 · Scientific Reports
Abstract Cardiovascular disease (CVD) is prevalent among older adults, but studies often focus on individual spouses rather than couple dynamics. This study examines how interplay between spouses—specifically discordance in gender role attitudes—relates to CVD risk biomarkers, using couple-matched data from the Korean Social Life, Health, and Aging Project (KSHAP) on 308 older married couples (616 individuals). Actor-partner interdependence models (APIM) reveal that discordant gender role attitudes are significantly associated with higher CVD risk markers—higher systolic blood pressure, higher
View details →Han SB · 2017 · Clinical Interventions in Aging
Sang Beom HanDepartment of Ophthalmology, Kangwon National University Hospital, Kangwon National University Graduate School of Medicine, Chuncheon, Republic of KoreaI read with great interest the article by Ahn et al1 entitled “Sex differences in the effect of aging on dry eye disease”, in which the authors revealed the sex differences in the effect of aging on dry eye disease (DED) in Korean adult population. They also showed the differences in patterns of DED following ocular surgery according to sex.1 The large population-based cross-sectional study was undoubtfully well designe
View details →Chen Zhang, Yuanyuan Wang, Wei Xie et al. · 2024 · BMC Public Health
Abstract Background Hypertension is one of the major public health problems in China. Limited evidence exists regarding sex differences in the association between hypertension and air pollutants, as well as the impact of dietary factors on the relationship between air pollutants and hypertension. The aim of this study was to investigate the sex-specific effects of dietary patterns on the association between fine particulate matter (PM2.5), ozone(O3) and hypertension in adults residing in Jiangsu Province of China. Methods A total of 3189 adults from the 2015 China Adult Chronic Disease and Nut
View details →Yongchao Zhang, Shanshan Chen, Hualei Chen et al. · 2023 · Cancer Medicine
Abstract Background The association between Glasgow Prognostic Score (GPS) and the modified Glasgow Prognostic Score (mGPS) and clinical outcomes in patients receiving immune checkpoint inhibitors (ICIs) remains controversial. Thus, this meta‐analysis aimed to examine the prognostic performance of GPS and mGPS in patients treated with ICIs. Methods Eligible studies were retrieved from searches of EMBASE, PubMed, Web of Science, and Cochrane Library until July 2021. The hazard ratio (HR) and 95% confidence intervals (CIs) were pooled by using fixed‐effect or random‐effects model to evaluate the
View details →Pear Pongsachareonnont, Nopphawan Uramphorn, Nuchanad Hounnaklang · 2018 · International Journal of Ophthalmology
AIM: To evaluate the association between visual impairment (VI) and mental health or social engagement in older adults living in rural Thailand. METHODS: Data for this cross-sectional study were drawn from a community survey conducted in 2015 in Saraburi Province, Thailand. Participants were 327 adults aged ≥50y. VI was assessed using presenting distance visual acuity. Mental health and social engagement were evaluated in face-to-face interviews using validated questionnaires. After determining the prevalence of VI and relevant sociodemographic characteristics, multivariate regression analysis
View details →Megumi Yokota, Akira Hirasawa, Kazuya Makita et al. · 2015 · Menopause Review
Introduction : Bilateral salpingo-oophorectomy (BSO) is a risk factor for osteoporosis. Previous studies have reported an association between genetic polymorphisms and the risk of developing osteoporosis. However, the relationship between osteoporosis and genetic polymorphisms in Japanese women treated with BSO is not well understood. To improve the quality of life for post-BSO patients, it is important to determine the genetic factors that influence their risk for osteoporosis. The aim of this study was to investigate the association between gene variations of estrogen metabolism-related gene
View details →Mehmet Yortanlı, Ramazan Köylü, Öznur Köylü et al. · 2025 · Eurasian Journal of Emergency Medicine
Aim: This study aimed to evaluate the diagnostic and prognostic significance of serum beta-trace protein (BTP) levels in patients diagnosed with sepsis in the emergency department. Materials and Methods: This prospective, single-center, observational clinical study was conducted in the emergency department and intensive care unit of a tertiary hospital. A total of 104 sepsis patients and 48 healthy adult volunteers who presented to the emergency department between April 2015 and October 2015 were included. Blood samples were collected on days 1 and 3, and BTP levels were measured using the ELI
View details →Aditi Prayag, Salima Bijapuri, Shweta Bhatbolan et al. · 2025 · Journal of Clinical and Diagnostic Research
Introduction: Breastmilk is recognised as the best infant nutrition, but Exclusive Breastfeeding (EBF) rates remain as low as 63.7% in India and 48% worldwide. One barrier is the development of Musculoskeletal Disorders (MSDs) in postpartum mothers due to a lack of education on proper breastfeeding posture. These factors can impact the quality of the infant’s latch, resulting in early cessation of breastfeeding. Aim: This study aimed to assess the impact of ergonomic breastfeeding on the risk of developing MSD in lactating mothers and infant latch quality. Materials and Methods: The present qu
View details →Yaser Mokhayeri, Seyed Saeed Hashemi-Nazari, Mohammad Ali Mansournia et al. · 2017 · Epidemiology and Health
OBJECTIVES Although the effect of physical activity (PA) on the incidence of atrial fibrillation (AF) has been studied, contradictory results have been reported. Such discrepancies may reflect the different effects of various types of PA upon AF, as well as gender interactions. Therefore, we aimed to evaluate the associations of PA types (total, moderate/vigorous, and intentional), as well as walking pace, with AF risk in men and women. METHODS Using the Multi-Ethnic Study of Atherosclerosis Typical Week Physical Activity Survey, 3 PA measures and walking pace were calculated among 6,487 men a
View details →Agus Arijanto · 2022 · Cognizance Journal of Multidisciplinary Studies
This study aims to analyze the effect of transformational leadership style and work motivation on employee organizational citizenship behavior (OCB) mediated by employee job satisfaction. The object of the research is employees of PT.…
View details →Adediwura Oladunni Arowosegbe, Iyabode Olabisi Dedeke, Olufunke Bolatito Shittu et al. · 2023 · Annals of Global Health
Background: In resource-poor settings, perinatal infections contribute significantly to maternal and neonatal deaths, and the use of clean delivery kits (CDKs) has been proposed as a tool to reduce the risk of infection-related deaths. This study aims to assess the acceptability and effectiveness of CDKs in preventing infections in deliveries attended by traditional birth attendants (TBAs) in Abeokuta, Nigeria. Methods: The study was a cluster-randomized trial with 67 birth centres/clusters, 453 births/mothers, and 457 babies randomized to intervention or control arms; intervention involved su
View details →Naoya Hasegawa, Masafumi Fukuda · 2020 · Epilepsy & Behavior Reports
We investigated the efficacy of lacosamide (LCM) polytherapy in improving seizure outcomes and psychiatric symptoms in patients with epilepsy with psychiatric comorbidities. We retrospectively collected data from medical records of outpatients of the Department of Psychiatry of Nishiniigata Chuo Hospital Epilepsy Center in Japan. We extracted data from all patients with epilepsy and psychiatric comorbidities who had been treated with LCM. We evaluated seizure prognosis and changes in psychiatric symptoms after LCM polytherapy. After LCM administration, 19 (47.5%) patients had improvements in s
View details →Onyinyechi Bede-Ojimadu, Nwakasi Nnamah, Jude A. Onuegbu et al. · 2025 · Scientific Reports
Abstract The ability of selenium to both prevent and induce cancer at varying biological concentrations has been reported in previous studies. We studied the associations between selenium exposure and prostate diseases such as prostate cancer (PCa) and benign prostatic hyperplasia (BPH), and estimated the optimal range of selenium concentrations that may be needed to prevent these diseases among Nigerian men. Blood and urine samples from men with histologically diagnosed PCa (n = 90), BPH (n = 97), and controls (n = 98) were analyzed for trace elements, including selenium. The associations bet
View details →Itzhak David Simão Kaveski, Antonio Maria da Silva Carpes, Roberto Carlos Klann · 2015 · Revista Catarinense da Ciência Contábil
O presente artigo tem por objetivo identificar os fatores que explicam o nível de divulgação relativo ao CPC 27 – Ativo Imobilizado, por empresas listadas no segmento do Novo Mercado de Governança Corporativa da BM&FBovespa, considerando como seus prováveis determinantes as variáveis tamanho, imobilizado total, endividamento e rentabilidade do imobilizado. O estudo caracteriza-se como descritivo, conduzido por meio de análise documental e abordagem quantitativa. A população é composta de 109 empresas em 2011, abrangendo uma amostra de 106 empresas. Para coleta dos dados foi elaborado um check
View details →Sabrina E.M. Almeida, Luciana B.S. Santos, Daniel T. Passos et al. · 2008 · Genetics and Molecular Biology
The genetic diversity of a single nucleotide polymorphism (SNP) at the exon 20 (T945M) of the leptin receptor gene (LEPR) and of three short tandem repeats (STRs BM7225, BMS694, and BMS2145) linked to LEPR was investigated in three beef cattle herds (Brangus Ibagé, Charolais, and Aberdeen Angus). A cheap and effective new method to analyze the T945M polymorphism in cattle populations was developed and the possible role of these polymorphisms in reproduction and weight gain of postpartum cows was evaluated. High levels of genetic diversity were observed with the average heterozygosity of STRs r
View details →Camila Salazar-Fernández, María José Baeza-Rivera, Diego Manríquez-Robles et al. · 2023 · Vaccines
The embrace of coronavirus disease 2019 (COVID-19) vaccine conspiracies has been linked to vaccine hesitancy. This study aimed to investigate the relationship between COVID-19 vaccine conspiracy theories and perceived vaccine effectiveness. The study utilized a longitudinal follow-up study in which adults in Chile completed surveys in December 2020 (T1) and May 2021 (T2). The psychometric properties of the five-item instrument on conspiracy theories for the COVID-19 vaccine were evaluated using data from T1 ( n = 578). A confirmatory one-factor structure with suitable indicators of reliability
View details →Jihye Kim, Carol J. Boushey, Lynne R. Wilkens et al. · 2022 · BMC Medicine
Abstract Background Plant-based diets assessed by a priori indices are associated with health outcomes. This study investigated the associations between pre-defined indices of plant-based diets and risk of colorectal cancer (CRC) and evaluated whether the association varies by sex, race and ethnicity, and anatomic subsite of tumors. Methods A total of 79,952 men and 93,475 women who participated in the Multiethnic Cohort Study were included. Primary outcome was incidence of invasive CRC. Cox models were used to estimate the risk of CRC across quintiles of three plant-based diet scores: overall
View details →Fumi Irie, Ryu Matsuo, Satomi Mezuki et al. · 2024 · Scientific Reports
Abstract Smoking has detrimental effects on the cardiovascular system; however, some studies have reported better clinical outcomes after thrombolysis for ischemic stroke in smokers than in nonsmokers, a phenomenon known as the smoking paradox. Therefore, this study aimed to examine the smoking paradox in patients with ischemic stroke receiving reperfusion therapy. Data were collected from a multicenter hospital-based acute stroke registry in Fukuoka, Japan. The 1148 study patients were categorized into current and noncurrent smokers. The association between smoking and clinical outcomes, incl
View details →Nuria Valdés, Nuria Valdés, Ana Romero et al. · 2024 · Frontiers in Endocrinology
IntroductionHistorically, Multiple Endocrine Neoplasia type 1 (MEN1)-related pituitary adenomas (PAs) were considered more aggressive and treatment-resistant than sporadic PAs. However, recent studies suggest similarities in their behavior. This study aimed to evaluate the long-term outcomes of MEN1 PAs and identify predictive factors.MethodsNationwide multicenter retrospective cohort study of MEN1-related PAs with a minimum 1-year follow-up, collecting patient demographics, germline MEN1 pathogenic variants (PV), PA size, secretory profile, radiological characteristics, treatments, and outcom
View details →Eman A Al Abdulsalam, Mohamed S Al-Hajjaj, Mohammad S Alanazi et al. · 2020 · Journal of Nature and Science of Medicine
Objectives: Several genes, including interleukin-13 (IL13), MS4A2, and IL 4 receptor alpha (IL4Rα), have been shown to associate with the inflammatory process in asthma. We investigated the possible association between asthma and five single-nucleotide polymorphisms (SNPs) in the IL13, IL4Rα, and MS4A2 gene in comparison with the level of the IL-13 protein in the Saudi asthmatics and controls. Subjects and Methods: The study group included 50 adult asthmatic patients and 50 normal healthy controls. Blood was extracted, and DNA was prepared. Genotyping was performed on DNA using direct sequenci
View details →Barrak Alahmad, Taofik Oyekunle, Claire Strohmeyer et al. · 2025 · Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Arrhythmia, particularly atrial fibrillation, is on the rise globally. While increased surveillance, aging populations, and other risk factors partially explain this rise, emerging risks such as extreme heat from climate change are underexplored. Methods We used Product Surveillance Registry by Medtronic (2016–2023) in the United States to examine patients with implantable cardioverter‐defibrillator or cardiac resynchronization therapy defibrillator devices. We identified first arrhythmic episodes (atrial tachycardia/fibrillation [AT/AF] or ventricular tachycardia/fibrillation) reco
View details →Kollipara Sumanth, Uma Sinharoy, Anindita Joardar et al. · 2026 · Annals of Indian Academy of Neurology
Background and Objectives: Epilepsy, with its complex interplay of neurobiological, genetic, and pharmacological factors, continues to challenge neurologists worldwide—particularly in managing drug resistance. This study aimed to evaluate the frequency of the SCN1A and SCN2A gene polymorphisms among patients with epilepsy (PWE) from Eastern India to assess their relationship with clinical profiles, electroencephalography (EEG) findings, and response to antiseizure medication. Methods: In this case–control genetic association study, a total of 110 PWE were assessed for demographic and clinical
View details →Muller Susan, Bouquot Jerry, Lou Yahuan et al. · 2007 · BMC Cancer
Abstract Background TRAIL plays an important role in host immunosurveillance against tumor progression, as it induces apoptosis of tumor cells but not normal cells, and thus has great therapeutic potential for cancer treatment. TRAIL binds to two cell-death-inducing (DR4 and DR5) and two decoy (DcR1, and DcR2) receptors. Here, we compare the expression levels of TRAIL and its receptors in normal oral mucosa (NOM), oral premalignancies (OPM), and primary and metastatic oral squamous cell carcinomas (OSCC) in order to characterize the changes in their expression patterns during OSCC initiation a
View details →Raissa Massaia Londero Chemello, Elsa Regina Justo Giugliani, Renan Rangel Bonamigo et al. · 2011 · Anais Brasileiros de Dermatologia
FUNDAMENTOS: Não há consenso quanto ao efeito do aleitamento materno no desenvolvimento da dermatite atópica. É necessário aprofundar conhecimentos sobre possíveis fatores envolvidos nessa relação, como a influência do aleitamento materno na colonização do paciente atópico pelo Staphylococcus aureus (S. aureus). OBJETIVO: Avaliar uma potencial associação entre aleitamento materno e colonização pelo S. aureus nas crianças atópicas. MÉTODOS: Estudo transversal envolvendo 79 crianças atópicas de 4-24 meses, de ambos os sexos, em acompanhamento no Ambulatório de Dermatologia Sanitária de Porto Ale
View details →Fery Mai Rafanan, Eduard Alfanta, Romulus Roberto Peter Instrella · 2024 · Philippine Journal of Otolaryngology Head and Neck Surgery
Objective: To investigate the association between the time intervals of key clinical time points and tumor progression (increase in clinical staging) in head and neck cancer patients before and during the pandemic. Methods: Design: Retrospective Cohort Study Setting: Tertiary Government Training Hospital Participants: A total of 81 head and neck cancer patients who consulted at the OPD and underwent elective surgery between January 1, 2018, and December 31, 2022, under the Department of Otorhinolaryngology – Head and Neck Surgery of East Avenue Medical Center were included in the study; 40 pat
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