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20,233 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessScience

Impact of Animal By-Products on Diet Digestibility and Fecal Quality in Beagle Dogs

Bussarakam Chuppava, Diana-Christin Siebert, Christian Visscher et al. · 2023 · Life

In animal feeds and pet food, meat industry rendered by-products as a source of high-quality protein are commonly used. Among all rendered protein sources, poultry carcasses and neck meal are frequently used as ingredients in commercial pet foods due to their agreeable fatty acid and amino acid profiles, and they have no impact on the palatability of the diet. Nonetheless, it is unclear how poultry by-product meal affects companion animals regarding diet digestibility and fecal quality. This study either aimed to provide information on poultry by-product meal, including coarsely, finely, or ve

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Negative / Null Result ReportOpen accessMedicine

Functional MR Microimaging of Pancreatic β-Cell Activation

Barjor Gimi, Lara Leoni, Jose Oberholzer et al. · 2006 · Cell Transplantation

The increasing incidence of diabetes and the need to further understand its cellular basis has resulted in the development of new diagnostic and therapeutic techniques. Nonetheless, the quest to noninvasively ascertain β-cell mass and function has not been achieved. Manganese (Mn)-enhanced MRI is presented here as a tool to image β-cell functionality in cell culture and isolated islets. Similar to calcium, extracellular Mn was taken up by glucose-activated β-cells resulting in 200% increase in MRI contrast enhancement, versus nonactivated cells. Similarly, glucose-activated islets showed an in

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Negative / Null Result ReportOpen accessAnimal culture

Saccharomyces Boulardii and Saccharomyces Cerevisiae Improve Immunity in Broilers Vaccinated Against Pasteurella Multocida and Salmonella Gallinarum

C Von Mühlen, NL Conrad, AP Roll et al. · 2025 · Brazilian Journal of Poultry Science

ABSTRACT This study evaluated the impact of dietary Saccharomyces boulardii and Saccharomyces cerevisiae on the immunity of birds vaccinated against Pasteurella multocida and Salmonella gallinarum. A total of 105 male Cobb 500 broilers were divided into four groups: T1 (vaccinated, no supplement, n = 30), T2 (vaccinated, S. boulardii supplement, n = 30), T3 (vaccinated, S. cerevisiae supplement, n = 30), and T4 (non-vaccinated, no supplement, n = 15). Chickens received a corn-soy diet with 1x107 CFU/g of S. boulardii or S. cerevisiae for 42 days. Immune response was assessed by indirect ELISA

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Negative / Null Result ReportOpen accessTherapeutics. Pharmacology

Synchronic Effect of Curcumin and swimming training on depression in morphine addicted male mice

L Elhampour, MA Azarbayjani, M Nasehi et al. · 2017 · Journal of Medicinal Plants

Introduction: There is need to more research because of extent drug trade in country and diversity of proposal cures such as non pharmacological ways including exercise and herbal medicine. The aim of the study: The aim of this study was study of synchronic effect of Curcumin and swimming training on depression in morphine addicted male mice. Methods: In an experimental research, 40 Albino NMRI male mice with 19- 21 gr were selected as subjects and they were divide randomly to care groups of control, morphine, swim training, Curcumin, swim training+ Curcumin. Subjects swam 60 min/day, 5 days/w

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Negative / Null Result ReportOpen accessAnimal culture

Effect of Dietary Zeolite Supplementation on Production, Egg Quality, Ammonia Volatilization, Organ Morphometry and Blood Parameters in Brown Laying Hens

RB Vieira, MCMM Ludke, JV Ludke et al. · 2023 · Brazilian Journal of Poultry Science

ABSTRACT The objective was to examine the effects of supplementing different levels of zeolite in the diet of laying hens during the laying phase, at 54 weeks of age, on production performance, egg quality, ammonia volatilization, excreta pH, blood parameters, weight, and organ morphometry. The treatments consisted of a control diet free of zeolite and five diets including increasing levels of zeolite (0.7, 1.4, 2.1, 2.8, and 3.5%). A completely randomized design was adopted with eight replicates of five birds per plot, totaling 240 laying hens, for four 28-day periods. Results were subjected

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Negative / Null Result ReportOpen accessAccounting. Bookkeeping

PENGARUH PENGETAHUAN WAJIB PAJAK, KESADARAN WAJIB PAJAK, DAN PROGRAM SAMSAT CORNER TERHADAP KEPATUHAN WAJIB PAJAK KENDARAAN BERMOTOR

Dewi Kusuma Wardani, Moh. Rifqi Asis · 2017 · Akuntansi Dewantara

This study aimed to examine the effect of knowledge of the taxpayer, the taxpayer awareness, and Program SAMSAT Corner on tax compliance in the Motor Vehicle Galeria Mall. The data used in this study are primary data from the results of questionnaires. Respondents in this study Motor Vehicle Taxpayers who make tax payments in SAMSAT Corner Galeria Mall Yogyakarta. The questionnaire was distributed to 108 respondents and data that can be processed as many as 105 questionnaires. The sampling method using Accidental Sampling. Data analysis techniques in this study using multiple linear regression

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Negative / Null Result ReportOpen accessNutrition. Foods and food supply

Effect of glgB/GASBD fusion gene expression on increased branching degree of potato starch and changes in physicochemical properties of starch

Yun-Feng Zhang, Yu-Ling Tang, Meng-Jun Jiang et al. · 2020 · International Journal of Food Properties

The objective of this study was to investigate the influence of granule-bound starch-binding domain fusion gene expression on the structure and properties of potato starch. The glgB/GASBD fusion gene and the glgB gene for control were transferred into the potato cultivar Desiree using Agrobacterium-mediated method, which were expressed in potato tubers driven by the potato granule-bound starch synthase gene promoter. The accumulation of glgB/GASBD fusion protein in starch granules was analyzed by Western blot hybridization. A large amount of glgB/GASBD fusion protein was found to accumulate in

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Negative / Null Result ReportOpen accessTherapeutics. Pharmacology

Organic mononitrites of 1,2-propanediol act as an effective NO-releasing vasodilator in pulmonary hypertension and exhibit no cross-tolerance with nitroglycerin in anesthetized pigs

Nilsson KF, Goździk W, Frostell C et al. · 2018 · Drug Design, Development and Therapy

Kristofer F Nilsson,1,2 Waldemar Goździk,3 Claes Frostell,4 Stanisław Zieliński,3 Marzena Zielińska,3 Kornel Ratajczak,5 Piotr Skrzypczak,5 Sylwia Rodziewicz,5 Johanna Albert,6 Lars E Gustafsson1,† 1Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden; 2Department of Cardiothoracic and Vascular Surgery, Faculty of Medicine and Health, Örebro University, Örebro, Sweden; 3Department of Anaesthesiology and Intensive Therapy, Wroclaw Medical University, Wroclaw, Poland; 4Department of Anesthesia and Intensive Care, Danderyd Hospital, Stockholm, Swede

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Negative / Null Result ReportOpen accessDentistry

Antifungal Efficacy of a Permanent Silicon Soft Liner Containing Silver Nanoparticles

Sareh Habibzadeh, Solmauz Eskandarion, Seyed Mahmoud Amin Marashi et al. · 2021 · Frontiers in Dentistry

Objectives: This study aimed to evaluate the in vitro antifungal efficacy of addition of silver nanoparticles (SNPs) to Mucopren® silicone soft liner material. Materials and Methods: Twenty disc samples (8 × 2 mm) of Mucopren® silicone soft liner containing 0wt% (control), 0.5wt%, 1wt%, 2wt%, and 3wt% SNPs were fabricated. Samples were powdered and added to 150 mL of Sabouraud dextrose agar culture medium and placed on separate culture dish plates. Each plate was inoculated with 106 colony forming units per milliliter (CFUs/mL) of Candida albicans (PTCC 5027) according to the CLSI protocol, an

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Negative / Null Result ReportOpen accessBusiness

KEBIJAKAN DIVIDEN DAN BI RATE SEBAGAI PEMODERASI LIKUIDITAS, PROFITABILITAS, DAN LEVERAGE TERHADAP NILAI PERUSAHAAN PERBANKAN YANG TERDAFTAR DI BEI TAHUN 2011-2017

Ananto Dwi Antoro, Sri Hermuningsih · 2018 · Upajiwa Dewantara: Jurnal Ekonomi, Bisnis dan Manajemen Daulat Rakyat

The purpose of this study is dividend payout ratio and BI Rate as moderation of liquidity, profitability, and leverage on financial firm value in Indonesia Stock Exchange within period 2011-2017. Research using purposive sampling method for taking sample, as many as 10 banks based on criteria. The research used secondary data from company’s annual report. The data were analyzed by using SPSS and SmastPls 3.2.7. The result showed that :1) the Liquidity and BI Rate have negative effect on company’s value but the effect were not significant, 2) profitability has a positive significant effect on f

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Negative / Null Result ReportOpen accessSports medicine

Safety and Effectiveness of a Perturbation-based Neuromuscular Training Program on Dynamic Balance in Adolescent Females: A Randomized Controlled Trial

Alison Bulow, Judith E Anderson, Jeff R S Leiter et al. · 2021 · International Journal of Sports Physical Therapy

# Background Adolescent females are at much greater risk for ACL injury than their male counterparts when participating in the same sports. Preventative and pre-operative rehabilitation neuromuscular (NM) exercise programs are often recommended to improve knee function and reduce injury rates. The effectiveness of perturbation-based NM training program has been established in an adult population but has yet to be investigated in the at-risk adolescent female population. # Purpose To determine the effectiveness of a perturbation-based NM exercise program in a group of physically active adolesce

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Negative / Null Result ReportOpen accessGeography (General)

An Analysis on the Urban Identity Element of Sabzevar with Emphasis on the Views of Citizens

Fatemeh Hajari, Yaghoob Zanganeh, Alireza Hamidian · 2018 · تحقيقات جغرافيايی

Introduction and Background: The issue of identity in general and urban identity in particular has a great importance because of the role that play in recognizing individuals, objects, communities and places. In spite of the importance of this issue, urban identity crisis is alarming in recent times. Natural elements, physical and socio-cultural components are three main elements identifying that conditions and characteristics of each of them determining their role in the identity of the city. Aims: The main purpose of this study is investigate and identify the urban identity component of Sabz

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Negative / Null Result ReportOpen accessSurgery

A compara tive analysis of short-term patient outcomes after laparoscop ic versus robotic rectal surgery

Chi Zhaocheng · 2022 · 结直肠肛门外科

[Background] The popularity of robot-assisted colorectal surgery has risen over recent years; however, patient-related advantages over laparoscopic surgery remain uncertain. [Objective] The goal of this study was to compare short-term patient outcomes following robotic and laparoscopic partial or complete rectal resections. [Design] This was a retrospective cohort study. [Settings] The study was conducted at 5 large tertiary care Kaiser Permanente medical centers across Southern California. [Patients] There were 863 consecutive robotic and laparoscopic pelvic rectal surgeries, including low an

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Negative / Null Result ReportOpen accessMedicine (General)

Association of Apolipoprotein E Polymorphism with Ischemic Stroke Subtypes in Taiwan

Chiou-Lian Lai, Ching-Kuan Liu, Ruey-Tay Lin et al. · 2007 · Kaohsiung Journal of Medical Sciences

The aim of this study was to clarify whether the apolipoprotein E gene (APOE) is related to ischemic stroke subtypes in Taiwan's Chinese population. Using the classification of Cerebrovascular Diseases III, 143 patients with lacunar infarction, 114 patients with atherothrombotic infarction, and 112 healthy controls were enrolled. APOE genotype was determined using polymerase chain reaction. Regarding the distribution of APOE genotypes, the frequency of ϵ3/ϵ4 genotypes in lacunar patients was significantly different from that in control subjects, by logistic regression, using ϵ3/ϵ3 as a referen

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Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system

Risk of Ischemic Heart Disease in Patients With Postpancreatectomy Diabetes and Pancreatic Cancer: A Population‐Based Study

Daegwang Yoo, Minsun Kang, Jaehun Jung · 2023 · Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

Background Postpancreatectomy diabetes can be caused by resection of functioning pancreatic tissue and is associated with postoperative pancreatic islet cell mass loss and subsequent endocrine dysfunction. Diabetes is a well‐known risk factor for ischemic heart disease. However, no previous studies have investigated ischemic heart disease in patients with postpancreatectomy diabetes and pancreatic cancer. Methods and Results Rates of patients with diabetes diagnosed with pancreatic cancer who underwent pancreatectomy between 2002 and 2019 in South Korea were obtained from the Korean National H

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Negative / Null Result ReportOpen accessMedicine

Corneal dendritic cells and the subbasal nerve plexus following neurotoxic treatment with oxaliplatin or paclitaxel

Jeremy Chung Bo Chiang, David Goldstein, Azadeh Tavakoli et al. · 2021 · Scientific Reports

Abstract Immune cell infiltration has been implicated in neurotoxic chemotherapy for cancer treatment. However, our understanding of immune processes is still incomplete and current methods of observing immune cells are time consuming or invasive. Corneal dendritic cells are potent antigen-presenting cells and can be imaged with in-vivo corneal confocal microscopy. Corneal dendritic cell densities and nerve parameters in patients treated with neurotoxic chemotherapy were investigated. Patients treated for cancer with oxaliplatin (n = 39) or paclitaxel (n = 48), 3 to 24 months prior to assessme

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Negative / Null Result ReportOpen accessMaterials of engineering and construction. Mechanics of materials

Experimental study on bone grinding temperature and force under low temperature spray cooling

Lihui ZHANG, Shuo XIE, Mingfa LUO et al. · 2024 · Jin'gangshi yu moliao moju gongcheng

Objectives: Bone tissue grinding is one of the common and basic applications in orthopedic surgery clinics. The grinding process is energy-intensive and generates a lot of grinding heat. The accumulation of this heat may cause thermal damage to biological tissues. This paper presents experimental research to investigate the bone-grinding heat and the cooling method. Methods: The combined influence of nozzle position and feed direction on the cooling effect of bone grinding under cryogenic spray cooling conditions is experimentally investigated. A bone grinding platform with three-dimensional m

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Negative / Null Result ReportOpen accessMedicine

Exercise preserves muscle mass and force in a prostate cancer mouse model

Darpan I. Patel, Kira Abuchowski, Bilal Sheikh et al. · 2019 · European Journal of Translational Myology

The purpose of this study was to examine the effects of exercise in modulating biomarkers of sarcopenia in a treatment naïve transgenic adenocardinoma of the mouse prostate (TRAMP) model. Thirty TRAMP mice were randomized to either exercise (voluntary wheel running) or no-treatment control group for a period of 20 weeks. During necropsy, gastrocnemius muscles and prostate tumors were harvested and weighed. Gastrocnemius concentrations of myostatin, insulin-like growth factor (IGF)-1 and tumor necrosis factor (TNF)-α were quantified. Exercise mice had greater muscle mass than controls (p=0.04).

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Negative / Null Result ReportOpen accessTherapeutics. Pharmacology

Effect of evolocumab on the progression of intraplaque neovascularization of the carotid based on contrast-enhanced ultrasonography (EPIC study): A prospective single-arm, open-label study

Ju Chen, Faming Zhao, Faming Zhao et al. · 2023 · Frontiers in Pharmacology

Background and Purpose: The aim of this study was to explore the effect of half a year of evolocumab plus moderate-intensity statin treatment on carotid intraplaque neovascularization (IPN) and blood lipid levels.Methods: A total of 31 patients with 33 carotid plaques who received evolocumab plus statin treatment were included. Blood lipid levels, B-mode ultrasound and contrast-enhanced ultrasonography (CEUS) at baseline and after half a year of evolocumab plus statin therapy were collected. The area under the curve (AUC) reflected the total amount of acoustic developer entering the plaque or

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Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system

Influence of Two Various Durations of Resistance Exercise on Oxidative Stress in the Male Rat’s Hearts

Rafigheh Ghiasi, Mustafa Mohammadi, Javad Ashrafi Helan et al. · 2015 · Journal of Cardiovascular and Thoracic Research

Introduction: The previous studies have suggested that alteration in oxidative stress and antioxidant defense depends on various factors, such as mode, intensity, frequency and duration of exercise. In this study, we compared the effects of two various durations of resistance exercise (1 month and 4 month) on oxidative stress and antioxidant status in cardiac tissue. Methods: Thirty Wistar male rats divided into 3 groups: control (sedentary), exercise-1 (regular exercise for 1 month) and exercise-2 group (regular exercise for 4 months). After the final to the experiment, the rats were anesthet

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Negative / Null Result ReportOpen accessDentistry

Effect of time in hardness test on artificially demineralized human dental enamel

Mirian de Waele Souchois Marsillac, Alberto Carlos Botazzo Delbem, Ricardo de Sousa Vieira · 2016 · Brazilian Journal of Oral Sciences

A cross-sectional microhardness (CSMH) test was carried out in human dental enamel exposed to a demineralizing solution in order to evaluate two different times of indentation in sound tissue and artificially induced caries. Twenty caries-free extracted human molars had one of their smooth surfaces sectioned and the enamel surface was isolated with nail polish except for an area of 6 mm2 . These specimens were submitted to artificially induced enamel caries on a lactate buffer containing 0.1 ppm fluoride (F) during 28 days. All specimens were bisected to create groups A and B in which CSMH tes

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Negative / Null Result ReportOpen accessMedicine

Cultural landscape perception of the Chinese traditional settlement: Based on tourists’ online comments

Jingjing Zhou, Shanshan Wu, Xiaojing Wu et al. · 2023 · PLoS ONE

The cultural landscape in traditional settlements is an important historical and cultural resource created by human beings in the process of historical evolution, and is an important resource for the development of traditional settlement tourism. This paper selected 21 representative traditional settlements for research using online comments from tourists as data and content analytical methods including high-frequency vocabulary, semantic networks and emotional attitudes to explore the public perspective on the connotations of cultural landscape features in traditional settlements. There are f

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Negative / Null Result ReportOpen accessDentistry

Demographic variations in the coping ability of people living with HIV/AIDS in Nigeria: implications for counseling

M. A. Adedigba, O. O. Ojo, E. O. Ogunbodede et al. · 2008 · Nigerian Dental Journal

Objective: To determine the coping ability of people living with HIV/AIDS (PLWHA) across demographic variations of gender, duration of living with HIV infection, marital status and living arrangements either with the family or alone. Method: The research design adopted in this study was descriptive survey. The population consisted of all PLWHA in Nigeria. The sample comprised of 117 PLWHA attending clinic regularly at General Hospital Ilesa, Osun State, Nigeria. The subjects had all been exposed to voluntary counselling and testing (VCT). Only those who consented participated in the study. A s

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Negative / Null Result ReportOpen accessTherapeutics. Pharmacology

Evaluation of Hand Stereognosis Level in 3-6 years Old Children with Spastic Hemiplegia and Diplegia

Minou Kalantari, Madineh Hassani, Kazem Hassani et al. · 2013 · Journal of Rehabilitation

Objective: One of the most prevalent sensory problems in cerebral palsy is Astereognosis which has special importance in daily manual functions. The purpose of this study was to determine the level of hand stereognosis using common objects and geometric shapes in children with spastic hemiplegia and diplegia. Materials & Methods: In this cross sectional study, 20 children with cerebral palsy between 3-6 years old (9 males, 11 females) with mean age (hemiplegya: 55months, diplegya: 57months) were selected through nonrandomized convinience sampling referd to Occupational Therapy centers of Shahi

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Negative / Null Result ReportOpen accessDentistry

The potential of rambutan honey toothpaste in reducing the dental plaque index: a quasi Experimental study

Euis Reni Yuslianti, Anindya Sekar Ayu Ningrum, Hartanto Endrowahyudi · 2023 · Padjadjaran Journal of Dentistry

ABSTRACT Introduction: The accumulation of dental plaque is a common cause of dental and oral health problems such as caries and periodontitis, therefore it is necessary to control plaque. Brushing is the most effective way to control plaque. Currently, there are various toothpastes used by the people, one of which is herbal toothpaste. One of the herbal toothpastes that has an antibacterial potential is rambutan honey toothpaste. The purpose of this study was to analyze the effectiveness of rambutan honey toothpaste in reducing the dental plaque index. Methods: this research was Quasi Experim

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Negative / Null Result ReportOpen accessGynecology and obstetrics

Outcomes after elevation of serratus anterior fascia flap versus serratus muscle flap in direct-to-implant breast reconstruction following mastectomy: a prospective study

Lilian de Sá Paz Ramos, Jorge Villanova Biazús · 2024 · Revista Brasileira de Ginecologia e Obstetrícia

Abstract Objective: The purpose of this study was to compare postoperative pain between SF flap and serratus anterior muscle (SM) in direct-to-implant breast reconstruction. Methods: This is a prospective cohort study that included 53 women diagnosed with breast cancer who underwent mastectomy and one-stage implant-based breast reconstruction from January 2020 to March 2021. Twenty-nine patients (54.7%) had SF elevation, and 24 patients (45.3%) underwent SM elevation. We evaluated patient-reported early postoperative pain on the first day after surgery. Also, it was reported that all surgical

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Negative / Null Result ReportOpen accessSpecial aspects of education

Effect of positive thinking training on stress, anxiety, depression, and quality of life among hemodialysis patients: A randomized controlled clinical trial

Nasrin Shokrpour, Shima Sheidaie, Mehdi Amirkhani et al. · 2021 · Journal of Education and Health Promotion

BACKGROUND: Given the relationship between positivity interventions and psychological problems, this study aimed to investigate the effect of positive thinking training on stress, anxiety, depression, and quality of life of hemodialysis patients. MATERIALS AND METHODS: This is a quasi-experimental and interventional study conducted on 70 hemodialysis patients referred to Fasa hemodialysis centers, Iran, between April 2019 and October 2019. Patients were selected using a simple sampling method and randomly divided into control (n = 35) and intervention (n = 35) groups. The intervention group wa

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Negative / Null Result ReportOpen accessMedicine

Hyponatremia at Admission in Hospitalized Patients With COVID-19: Risk Factors and Impact on Prognosis

Negar Sheikhdavoodi, Maryam Gheraati, Sima Hashemipour et al. · 2022 · The Journal of Qazvin University of Medical Sciences

Background: Electrolyte disorders, particularly hyponatremia, have been reported in a considerable number of patients with Coronavirus Disease 2019 (COVID-19). Objective: The current study aims to evaluate the risk factors, symptoms, and prognosis of hyponatremia in hospitalized patients with COVID-19. Methods: In this retrospective cohort study, 467 patients with COVID-19 were divided into 4 groups based on the sodium level at the time of admission: normal, mild hyponatremia, moderate hyponatremia, and severe hyponatremia. Symptoms, laboratory findings, and prognosis were compared among these

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Negative / Null Result ReportOpen accessSurgery

Survival following orbital exenteration at a tertiary brazilian hospital

Juliana Mika Kato, Fabricio Lopes da Fonseca, Suzana Matayoshi · Revista do Colégio Brasileiro de Cirurgiões

Objective: to analyze the epidemiology, clinical features and survival rate of patients undergoing orbital exenteration (OE) in a tertiary referral hospital. Methods : we conducted a retrospective study of all patients undergoing OE at the Hospital das Clínicas, FMUSP between January 2007 and December 2012. We collected data records related to gender, age, origin, length of stay, duration of the disease, other treatments related to the disease, number of procedures outside of the face related to the disease, follow-up and histological diagnosis. Results : we treated 37 patients in the study pe

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Negative / Null Result ReportOpen accessSpecial aspects of education

Classroom-based language assessment literacy and professional development need between novice and experienced EFL teachers

Ima Fitriyah, Fitriatul Masitoh, Utami Widiati · 2022 · Indonesian Journal of Applied Linguistics

Classroom-based language assessment (CBLA) in the Indonesian context has become more significant since the shift of the assessment model from summative based assessment (Ujian Nasional or the final exam) to formative-based assessment (Asesmen Kompetensi Minimum (AKM); therefore, teachers need to develop their classroom-based language assessment literacy (CBLAL). The model places a greater emphasis on students' learning outcomes in class rather than final test scores. This study aims to examine the CBLAL level of experienced and novice EFL teachers, their perceptions of CBLAL, and their needs f

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