Negative / Null Result ReportMedicine
Peng P, Guo Y, Zhu Y · 2026 · Advances in clinical and experimental medicine : official organ Wroclaw Medical University
Background Given that long-term anticoagulant therapy is required in many clinical scenarios, continuous safety monitoring of direct factor Xa inhibitors is of great importance. To date, the renal safety of these agents remains a subject…
View details →Negative / Null Result ReportMedicine
Zhai L, Fang C, Wang L et al. · 2026 · Scientific reports
There is little evidence about the susceptible exposure window of maternal depression during pregnancy and preterm birth in China. We aimed to assess the trimester-specific association of depression during pregnancy with preterm birth, and…
View details →Negative / Null Result ReportOpen accessMedicine
Metwally YF, Zahran RF, El Sadda RR et al. · 2026 · Discover oncology
Background Lung cancer remains the leading cause of cancer-related deaths worldwide. Despite advances in diagnostics and treatment, most patients are diagnosed at advanced stages. Genetic variants such as single nucleotide polymorphisms…
View details →Negative / Null Result ReportMedicine
Aryal SB, Raj Joshi D · 2026 · Journal of Nepal Health Research Council
Background Homocysteine (Hcy) contributes to oxidative stress and renal injury by generating reactive oxygen species and reducing heme oxygenase-1 levels. Elevated Hcy (Hhcy) may worsen outcomes after acute renal failure(ARF), promoting…
View details →Negative / Null Result ReportMedicine
Bellos I, Marinaki S, Benetou V · 2026 · Journal of clinical medicine
Background/Objectives : Composite endpoints are commonly used in chronic kidney disease (CKD) trials to enhance statistical efficiency but may not reflect clinically meaningful outcomes. We assessed agreement between composite endpoints…
View details →Negative / Null Result ReportMedicine
Pires E Silva C, Malaspina OA, Basting RT · 2026 · General dentistry
Light transmission during photopolymerization is reduced by the intrinsic optical properties of ceramics, which vary with material and thickness. The higher translucency of lithium disilicate contrasts with the chemical inertness and…
View details →Negative / Null Result ReportMedicine
Hakim MS, Hashimi MH, Saeed KM et al. · 2026 · Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit
Background Viral hepatitis and HIV infections are common public health concerns among injecting drug users, however, there is limited evidence on their seroprevalence in Afghanistan. Aim To determine the seroprevalence of hepatitis B,…
View details →Negative / Null Result ReportOpen accessMedicine
Popovic R, Cvitanovic S, Sarac I et al. · 2026 · Cureus
Objective To assess parents' knowledge of recommended oral-hygiene practices for children and to describe oral-hygiene behaviors within families (parents and children), as well as factors associated with children's oral-hygiene outcomes.…
View details →Negative / Null Result ReportMedicine
Famuyide L, Patel J, Nembhard WN · 2026 · Birth defects research
Background Hypospadias is one of the most common genital defects in boys, affecting about 1 in 125 live-born boys. Several studies have examined the association between a single environmental exposure and risk of hypospadias, but few have…
View details →Negative / Null Result ReportOpen accessMedicine
Ye B, Liu Y, Zhang J et al. · 2026 · Frontiers in nutrition
Background To investigate the associations between consumption of sugar-sweetened beverages (SSBs), artificially sweetened beverages (ASBs), and natural juices (NJs) and incident kidney stone disease (KSD), and to assess whether genetic…
View details →Negative / Null Result ReportMedicine
Kılıç A, Koçak Ulucaköy R, Osmanov Z et al. · 2026 · Biomarkers in medicine
Objective Biomarkers that accurately reflect disease activity and inflammatory burden are needed, particularly in the early stages of spondyloarthropathy (SpA). This study aimed to evaluate the association between serum neopterin levels…
View details →Negative / Null Result ReportMedicine
Sussadee M, Jarudecha T, Muikaew R et al. · 2026 · Animals : an open access journal from MDPI
Feline hypertrophic cardiomyopathy (HCM) is the most common cardiac disease in cats, causing morbidity and mortality. Recently, a variant in the Alström syndrome protein 1 ( ALMS1 ) gene has been reported to be associated with HCM in…
View details →Negative / Null Result ReportMedicine
Choi SJ · 2026 · BMC public health
Background Walking is a widely accessible form of physical activity and has been consistently associated with improved health-related quality of life (HRQoL) at the individual level. However, less is known about how walking participation…
View details →Negative / Null Result ReportMedicine
McCaw K, Fink B, Danis D et al. · 2026 · American journal of veterinary research
Objective To compare the accuracy of a tibial plateau-leveling osteotomy (TPLO) using a modular guide (OssAbility) compared to the traditional freehand method. We hypothesized that guide use would improve TPLO centering and accuracy in the…
View details →Negative / Null Result ReportOpen accessMedicine
Gaba K, Kumar K, Kaushik R et al. · 2026 · Cureus
Background The use of post-mortem blood culture as a diagnostic tool in medico-legal autopsies is limited. Differentiating true infection from contamination or post-mortem bacterial translocation remains a challenge. This study aimed to…
View details →Negative / Null Result Report
Zehra J, Kumari C, Bibi A et al. · 2026 · Preprint
Abstract Objective This study aimed to investigate in-hospital mortality rates among different Mannheim Peritonitis Index (MPI) score groups in patients who underwent emergency laparotomy due to hollow viscus perforation. Methods We…
View details →Negative / Null Result ReportMedicine
Chaudhry A, Moin M, Malik TG et al. · 2026 · JPMA. The Journal of the Pakistan Medical Association
To determine the shape and size of foveal avascular zone in terms of perimeter, circularity, roundness and axial ratio using optical coherence tomography angiography. The retrospective study was conducted at the Yaqeen Vison Clinic,…
View details →Negative / Null Result ReportMedicine
He L, Wang K · 2026 · Medicine
Total bilirubin possesses antioxidant and immunomodulatory properties, and its role in childhood asthma is a topic of ongoing debate. We employed both a cross-sectional study and Mendelian randomization (MR) analysis to explore the link…
View details →Negative / Null Result ReportMedicine
Wei W, Shaibi GQ, Temkit H et al. · 2026 · Journal of pediatric hematology/oncology
Introduction Alkylators are gonadotoxic in a cumulative manner, with overall exposure quantified as the cyclophosphamide equivalent dose (CED). Inhibin B is used as a surrogate marker of fertility in adult male childhood cancer survivors…
View details →Negative / Null Result ReportOpen accessMedicine
Barghash M, Obayi E, Itaman U et al. · 2025 · Cureus
Background Hiatal hernia is commonly associated with gastro-oesophageal reflux disease (GORD). However, the relationship between hernia size and reflux severity remains unclear. This study aimed to assess the impact of the hiatal hernia…
View details →Negative / Null Result ReportOpen accessMedicine
Md Kasim NA, Shirinal Izuan US, Karuppannan M · 2026 · BMC health services research
BACKGROUND: Healthcare providers commonly recommend medication reminders as a strategy to enhance adherence to prescribed medications. Patient demographic characteristics may influence medication adherence and incorporating patient-centred…
View details →Negative / Null Result ReportOpen accessMedicine
Prates AJ, Curioni OA, Ramos DM et al. · 2026 · Diagnostics (Basel, Switzerland)
Background/Objectives: Laryngeal cancer has a high incidence and mortality rate, especially in advanced stages. Stoma recurrence after total laryngectomy is rare but lethal, and its risk factors remain controversial. We aimed to assess…
View details →Negative / Null Result ReportMedicine
Voigt MB, Böhner A, Bahaaeldin M et al. · 2026 · CVIR endovascular
To evaluate the occurrence of periaortic inflammation, including abscess formation, as a complication following endoleak repair after endovascular aortic repair. This retrospective single-center study analyzed 88 EVAR revisions for…
View details →Negative / Null Result ReportMedicine
Zhao N, Zhan Y, Choi J et al. · 2026 · The Journal of nutrition
Background The consumption of live microbes beyond probiotics is associated with health benefits. Despite growing interest in live microbe intake, comprehensive data on its dietary sources and research on their potential health effects in…
View details →Negative / Null Result ReportOpen accessMedicine
Mostafavi M, Rezazadeh F, Fattahi MJ et al. · 2026 · Journal of dentistry (Shiraz, Iran)
Background Multiple studies have revealed an association between vitamin D levels, genetic polymorphisms of the VDR (vitamin D receptor) gene, and the underlying causes of various bone and cartilage disorders. Purpose This study aimed to…
View details →Negative / Null Result ReportMedicine
Ozaki K, Nishioka Y, Kamitani F et al. · 2026 · Diabetes research and clinical practice
It has been controversial whether COVID-19 increases the risk of new-onset type 1 diabetes mellitus. Using large-scale claims data, we found no statistically significant association between COVID-19 and incident type 1 diabetes mellitus in…
View details →Negative / Null Result ReportOpen accessMedicine
Buran A, Altaş H, Özkaya Uçar Y et al. · 2026 · Journal of the Turkish German Gynecological Association
Objective To evaluate pathological findings in patients positive for human papillomavirus (HPV)-31. Material and methods This retrospective study included patients evaluated in a tertiary colposcopy clinic. The 3,546 patients tested for…
View details →Negative / Null Result ReportOpen accessMedicine
Braun S, Selkridge I, Nocon A et al. · 2026 · Arthroplasty (London, England)
Background Extensor mechanism disruption following total knee arthroplasty (TKA) significantly impairs knee function and quality of life. Extensor mechanism reconstruction (EMR) is effective but carries risks, including post-operative…
View details →Negative / Null Result ReportMedicine
Sarpeleh F, Ehtesham N, Mirjani R et al. · 2026 · Lupus
ObjectiveThe dysfunction of interleukin-7 receptor alpha (IL-7Rα), which is encoded by the IL7RA gene, has been implicated in the development of systemic lupus erythematosus (SLE). This study aimed to investigate the relationship between…
View details →Negative / Null Result ReportOpen accessMedicine
Mazurek A, Jankowski M, Grudziąż-Sękowska J · 2026 · BMC nephrology
BACKGROUND: The weekend effect refers to the observation that patients admitted to the hospital on the weekend experience poorer clinical outcomes than patients admitted during the workweek. This effect has not been previously studied…
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