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Browse the failure-mode index

19,859 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Comparing Spinal and General Anesthesia for Prone Percutaneous Nephrolithotomy: A Propensity Score-Matched Study.

Chen L, Xu D, Hou L · 2026 · Medical principles and practice : international journal of the Kuwait University, Health Science Centre

Background/objective Prone percutaneous nephrolithotomy (PCNL) is commonly performed under general anesthesia (GA); however, increasing evidence supports the feasibility of PCNL under spinal anesthesia (SA). This study presents our…

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Negative / Null Result ReportMedicine

Development and Preliminary Clinical Evaluation of a Multifunctional Operative Support Arm in Reproductive Laparoscopic Surgery: A Randomized Controlled Study.

Mao W, Lu N · 2026 · Journal of investigative surgery : the official journal of the Academy of Surgical Research

Objective To evaluate short-term clinical outcomes, surgeon-reported fatigue, and staff user experience associated with a multifunctional operative support arm in reproductive laparoscopic surgery. Design Single-center, parallel-group…

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Negative / Null Result ReportMedicine

Noninferiority trial of low-dose intravenous dexamethasone on the analgesic effect of caudal block in children undergoing day-case orchiopexy: a randomized clinical trial.

Lee JR, Choi H, Eum D et al. · 2026 · Anesthesia and pain medicine

Background Intravenous (IV) administration of dexamethasone has been reported to prolong the analgesic duration of a caudal block. The aim of this study was to compare the analgesic effects of IV low-dose and high-dose dexamethasone in…

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Negative / Null Result ReportMedicine

Impact of the amotosalen/UVA process to reduce pathogens in platelet concentrates on transfusion efficiency in cardiac surgery.

Bouali B, Rezzaoui A, Hamzeh-Cognasse H et al. · 2026 · Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine

Background Pathogen reduction treatment (PRT) of platelet concentrates (PC) is one of the most recent advances in improving blood safety and lowering the risk of transfusion-transmitted diseases. The characteristics of PR-treated PC differ…

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Negative / Null Result Report

Salivary Prevotella qPCR Signal as an Exploratory Non-Invasive Diagnostic Adjunct for Rotterdam Phenotype Stratification in Women with Polycystic Ovary Syndrome

Tunjungseto A, Hadi OA, Pratiwi IW et al. · 2026 · Preprint

Background: /Objectives: Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine-metabolic disorder, and Rotterdam-defined phenotypes may require more refined non-invasive adjunctive signals for phenotypic stratification. Saliva is a…

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Negative / Null Result ReportMedicine

The Efficacy of Local Treatment for Recurrent Endometrial Cancer.

Igasaki M, Furusawa A, Kunishi M et al. · 2026 · The journal of obstetrics and gynaecology research

Aim This study aimed to evaluate the efficacy of local treatment in patients with sporadic recurrent endometrial cancer. Methods We retrospectively reviewed patients who received treatment for first recurrence of endometrial cancer at our…

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Negative / Null Result ReportMedicine

Hip Fracture Risk Following Lumbar Fusion: A Retrospective Cohort Study of Construct Length and Age-Stratified Outcomes.

Anundson J, Lee L, Bae S et al. · 2026 · European journal of orthopaedic surgery & traumatology : orthopedie traumatologie

Introduction Lumbar fusion alters spinal biomechanics and may increase hip loading, especially with long-segment constructs. We used a large administrative database to evaluate hip fracture risk after lumbar fusion and assess whether…

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Negative / Null Result ReportMedicine

Effectiveness of a standardized patient simulation training programme on nursing students' skill in dementia screening in Malawi: A quasi-experimental study.

Chiona BC, Mbakaya BC, Liu MF · 2026 · Nurse education in practice

Aim To evaluate the effectiveness of Standardized Patient Simulation (SPS) compared with lecture-based teaching in improving dementia knowledge, dementia screening skills and mild cognitive impairment (MCI) classification accuracy among…

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Negative / Null Result ReportMedicine

Marginal Bone Loss Around Bone-Level Fully Guided Implants With Direct Implant Connection Versus Intermediate Abutment: A Randomized Clinical Trial.

Gargallo-Albiol J, Zilleruelo-Pozo MJ, Treserra-Parra A et al. · 2026 · Clinical oral implants research

Objective To determine the influence of an intermediate prosthetic abutment on peri-implant marginal bone loss (MBL) around two implant-supported fixed restorations in the posterior area. Material and methods This study included patients…

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Negative / Null Result ReportMedicine

Comparison of visual performance among three higher-order aspheric enhanced monofocal intraocular lenses and a standard aspheric monofocal lens.

Hayashi S, Yoshida M, Hayashi K et al. · 2025 · Journal of cataract and refractive surgery

Purpose To compare visual performance among 3 types of higher-order aspheric enhanced monofocal intraocular lenses (IOLs) and a standard aspheric monofocal IOL. Setting Hayashi Eye Hospital, Fukuoka, Japan. Design Randomized comparative…

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Negative / Null Result ReportMedicine

Day-case versus conventional inpatient artificial urinary sphincter implantation: A single-center comparative study of 177 patients.

Youssef MW, Perrin L, Denormandie AC et al. · 2026 · The French journal of urology

Purpose Ambulatory artificial urinary sphincter (AUS) implantation has been proposed as an alternative to conventional inpatient surgery, but comparative data remain limited. We aimed to compare early postoperative outcomes between…

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Negative / Null Result ReportMedicine

Evaluating junior medical staff confidence in assessment and management of mental health presentations in an Australian paediatric emergency department.

Daoud J, Greenwood J, Botha T et al. · 2026 · Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists

ObjectiveTo evaluate confidence levels of junior doctors working in the paediatric emergency department (ED) in the assessment and management of acute mental health presentations.MethodsThis cross-sectional study invited 89 eligible junior…

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