20,227 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Eldesoqui M, Al-Batati A, Erfan OS et al. · 2026 · Clinical anatomy (New York, N.Y.)
Generation Z has different requirements, problems, expectations, and attitudes that they bring into the educational environment. Teachers have unprecedented challenges in addressing their needs and aspirations. Gamification involves…
View details →Hassan AM, Elgarem HF, Sheta E et al. · 2026 · Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Objective Balloon dilation of the Eustachian tube (BDET) is increasingly used to treat pediatric obstructive Eustachian tube dysfunction (OETD); however, its broader adoption is limited by the cost of commercially available devices.…
View details →Metry M, Bernard S · 2026 · JAAPA : official journal of the American Academy of Physician Assistants
Abstract Heart failure (HF) is one of the most common and consequential conditions encountered in clinical practice. It frequently coexists with chronic kidney disease (CKD), a highly prevalent and economically burdensome condition. The…
View details →Golz C, Gerlach M, Meichtry A et al. · 2026 · Preprint
Abstract Background: Presenteeism behaviour, defined as working while ill, can negatively affect employee health and productivity. Despite its high prevalence, targeted theory-based interventions remain scarce. This study evaluated a…
View details →Flores Rodríguez JC, Morán Ortega MJ, Jimenez Ordoñez AC et al. · 2026 · Cureus
Postbiotics, defined as non-viable microbial cells and their metabolites, have emerged as topical therapies for inflammatory dermatoses and provide more clinical benefits than live postbiotics by eliminating infection risk and stability.…
View details →Cangemi DJ, Laitman AP, Faiman O et al. · 2026 · Annals of medicine
Introduction Constipation and bloating are common bothersome gastrointestinal (GI) symptoms that frequently occur concurrently. It is important to recognize the underlying condition(s) and tailor therapeutic interventions appropriately.…
View details →Gozde Ozdemir B, Avci F, Huseynli L et al. · 2026 · Pakistan journal of pharmaceutical sciences
Background Persistent infection with human papillomavirus (HPV) is a key factor in cervical carcinogenesis. Immune-mediated mechanisms play a central role in viral clearance, leading to interest in immunomodulatory supportive therapies.…
View details →Yang J, Han Y · 2026 · Food Hydrocolloids.
The development of non-fat whipped cream analogue (NFWCA) addresses the demand for low-fat and reduced-sucrose foods. This study systematically evaluated how the dextrose equivalent (DE) value of maltodextrin (MD) and the sucrose/MD ratio…
View details →Li G, Wang C, Gao Y et al. · 2026 · European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
OBJECTIVE: This study evaluated the efficacy and safety of multimodal outpatient therapy compared with conventional inpatient therapy during the initial treatment of sudden sensorineural hearing loss (SSNHL). The goal was to provide…
View details →Zhang Y, Sadeh N, Mitchell O et al. · 2026 · Irish journal of medical science
Aims There is no current gold standard in treating post-traumatic stiff (PTS) shoulder complicating conservatively managed proximal humeral fractures (PHFs). This scoping review seeks to present available outcome evidence in this cohort of…
View details →Parunakian E, Yehezkeli V, Khitri M et al. · 2026 · Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus
Syphilis can present with a wide range of ocular manifestations; however, scleritis is exceedingly rare. Although various infectious and noninfectious causes of scleritis following strabismus surgery have been documented, syphilitic…
View details →Jia Y, Dong Y, Jiang R et al. · 2026 · Journal of pediatric orthopedics
Background Sprengel deformity is a rare congenital malformation of the scapula. To date, there have been limited reports analyzing the clinical outcomes of the modified Woodward procedure and conservative management in the treatment of…
View details →Jiang Y, Ma L, Lu B et al. · 2026 · Frontiers in oncology
Pancreatic cancer continues to be one of the foremost contributors to cancer-related mortality. Erlotinib is a targeted agent that has shown a significant improvement in outcomes for advanced pancreatic cancer when administered alongside…
View details →Örnek K, Erşekerci TK · 2026 · GMS ophthalmology cases
A 65-year-old male patient received intravitreal bevacizumab for age-related macular degeneration. On the first day, he presented with ocular pain, corneal stromal infiltration and dense vitritis. Prompt intravitreal vancomycin and…
View details →Uzun M, Demir İ, Höl D · 2026 · Preprint
Abstract The integration of generative AI (GenAI) into second-language (L2) writing instruction has expanded rapidly, yet the timing of AI-generated feedback remains empirically underexplored. Grounded in Cognitive Load Theory, the…
View details →Weinzimmer LG, Hippler SE · 2026 · Journal of healthcare management / American College of Healthcare Executives
Goal Burnout in healthcare remains a significant problem, with implications not only for physicians and advanced practice providers but also for the entire US healthcare system, including patients and payers. Significant work has been done…
View details →Rathi M, Mali N, Gazbare P et al. · 2026 · BMC musculoskeletal disorders
BACKGROUND: Low back pain and temporomandibular Dysfunction (TMD) have a coexistence in clinical practice. To find the effect of temporomandibular exercises (TME) along with conventional physiotherapy in patients with mechanical low back…
View details →Kaplan DJ · 2026 · Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
A complex interplay exists between the hip joint and the lumbosacralpelvis. As a patient moves from a standing to seated position, the lower back, pelvis, and hips must move in concert to properly function. Conceptually, any deviation from…
View details →Mirza M, Fischer H, Arias D · 2026 · OTJR : occupation, participation and health
Background Aging adults with chronic diseases are at risk of functional decline. Objectives This pilot randomized control trial examined the feasibility, acceptability, and preliminary efficacy of an occupational therapy intervention to…
View details →Anand K, Nagpal V, Dutta P et al. · 2026 · Journal of pediatric ophthalmology and strabismus
Purpose To evaluate and compare unilateral recession-plication versus bilateral three-muscle surgery for large-angle exotropia. Methods A prospective interventional non-randomized comparative study was conducted involving 66 patients with…
View details →Mat Salleh F, Nizam I · 2026 · SICOT-J
Background Total Knee Arthroplasty (TKA) is the standard treatment for end-stage osteoarthritis, with optimal outcomes dependent on precise mechanical alignment and accurate implant positioning. Patient-specific instrumentation (PSI),…
View details →EL-Husseiny AM, Salem HH, Abdelfatah AM et al. · 2026 · Preprint
Abstract Background Chronic pain imposes significant impact on individuals and the health system as it is often accompanied by significant physical, emotional and social burden. It is frequently associated with anxiety disorders,…
View details →Saito T, Hirose T, Haruna T et al. · 2026 · The Journal of laryngology and otology
Objective. To compare subjective and psychophysical olfactory outcomes in patients with eosinophilic chronic rhinosinusitis controlled after primary functional endoscopic sinus surgery (FESS) alone versus those treated with dupilumab for…
View details →Erbas A, Duman S, Onder M et al. · 2026 · Preprint
Abstract Introduction: Comparative data for regenerative techniques in osteochondral lesions of the talus (OLT) remain limited. We compared the outcomes of a three-layered cell-free scaffold (ChondRoD) with osteochondral autograft…
View details →Awatade NT, Budden KF, Pathinayake PS et al. · 2026 · Preprint
Increasing evidence suggests that acquired dysfunction of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel occurs as a result of cigarette smoke exposure in Chronic obstructive pulmonary disease (COPD).…
View details →Song X, Wang Y, Chen H · 2026 · International journal of cardiology. Cardiovascular risk and prevention
Objective To identify distinct multi-year cognitive function trajectories in middle-aged and older Chinese adults with established cardiovascular disease (CVD) and evaluate their independent associations with all-cause mortality. Methods…
View details →Pham VX, Gilbertson E · 2026 · Cureus
This case report describes an 83-year-old female who developed severe psoriasiform lesions suspected to be induced by dupilumab. The patient initially presented with eczematous papules affecting her back, arms, torso, and scalp, and a…
View details →Espehana A, Macfarlane G, Garden EM et al. · 2026 · Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery
Objectives Tumour Necrosis factor antagonists is a potent anti-inflammatory medication and has shown to improve olfactory function in murine models. The primary aim was to determine the effect of TNF antagonists on olfactory performance in…
View details →Lin B, Schneider K, Ozgul M et al. · 2026 · Preprint
Abstract This study aimed to examine whether Humanin-G (HNG), a mitochondrial derived peptide with cytoprotective properties, could improve the retinal function and gene expression in Royal College of Surgeons (RCS) rats with retinal…
View details →Liu X, Shi J, Wang T · 2026 · Reproduction (Cambridge, England)
Polycystic ovary syndrome (PCOS) is a prevalent multifactorial disorder characterized by hormone dysregulation and follicular development defects. Asialoglycoprotein receptor 1 (ASGR1), a C-type lectin predominantly expressed on the…
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