Negative / Null Result Report
Nicolli A, Armani T, Buendía Arellano M et al. · 2026 · Preprint
Cryopreservation of ram semen induces structural and functional alterations that compromise sperm fertility. Since seminal plasma contributes to the regulation and preservation of sperm function, increasing attention has been directed…
View details →Negative / Null Result Report
Wahyono P, Ariesaka KM, Susetyarini E et al. · 2026 · Preprint
Background Limited male contraception choices have prompted the hunt for natural antifertility drugs. This experimental study investigates the antifertility effects of stigmasterol extracted from Pluchea indica leaves in male rats ( Rattus…
View details →Negative / Null Result ReportMedicine
Sun G, Lin W, Peng Y et al. · 2026 · BMC anesthesiology
Postoperative fatigue is a prevalent complication delaying early recovery after gynecological laparoscopic surgery, with no proven effective interventions. To investigate the effect of continuous intraoperative low-dose esketamine on…
View details →Negative / Null Result ReportOpen accessMedicine
Ciccarelli G, Monaco E, Nasso V et al. · 2026 · Journal of experimental orthopaedics
Purpose The purpose of this study was to quantify return-to-play (RTP) time, post-operative performance and market-value trends after proximal hamstring repair in top-tier European league soccer players. It was hypothesized that surgery…
View details →Negative / Null Result ReportMedicine
Deruelle P, Arcieri F, Martineau R · 2026 · Gynecologie, obstetrique, fertilite & senologie
Background Hyperemesis gravidarum (HG) remains one of the most disabling complications of the first trimester, with a high risk of recurrence after a prior episode that weighs heavily on family planning and on patients' mental health.…
View details →Negative / Null Result ReportOpen accessMedicine
Pak K, Yoon C, Sadda SR · 2026 · Eye (London, England)
Purpose To evaluate longitudinal change in hard exudate (HEs) volume over 5-years following anti-VEGF treatment for diabetic macular oedema (DMO). Methods This study was a post-hoc analysis of structural optical coherence tomography (OCT)…
View details →Negative / Null Result Report
Holgado D, Martínez-Pérez V, Martín-Arévalo E et al. · 2026 · Preprint
Inconsistent evidence regarding the cognitive effects of transcranial direct current stimulation (tDCS) highlights the need for more comprehensive approaches to assess its impact. This study aimed to investigate the effects of…
View details →Negative / Null Result ReportMedicine
Kim HSW, Cha S, Choi JY et al. · 2026 · The Journal of craniofacial surgery
This study compared the upper airway dimensions following maxillomandibular advancement (MMA) surgery in adults with obstructive sleep apnea (OSA) with those of normal controls. Korean adult OSA patients who underwent conventional MMA…
View details →Negative / Null Result ReportMedicine
Haflidadottir S, Helgadottir FD, Sighvatsson MB · 2026 · Scandinavian journal of psychology
The global burden of infertility and its associated psychological distress is substantial, yet many individuals face barriers to accessing psychological support. A scalable, low-cost online intervention presents a promising solution. A…
View details →Negative / Null Result Report
Yu C, Huang W, Yu B et al. · 2026 · Preprint
Synthetic 6-Br-Q0C10 has been shown to have a partial electron transfer activity of native coenzyme Q in the isolated mitochondria. It reduces energy coupling efficiency by 30 %, suggesting that it may be useful in the management of…
View details →Negative / Null Result Report
May R, Hernández Gómez MÁ, Aguirre Martínez JL et al. · 2026 · Preprint
One of the most notable impacts of wind energy is bird mortality due to collisions with wind turbines, making it necessary to adopt measures to prevent or mitigate this impact. In recent years, studies have been carried out to test the…
View details →Negative / Null Result ReportOpen accessMedicine
Leal Barbosa V, Westenhofen D, Scherdien Silva P et al. · 2026 · Lasers in medical science
Purpose To evaluate the efficacy of 8% arginine-based desensitizing toothpaste and photobiomodulation (PBM), used alone or in combination, in the treatment of dentin hypersensitivity (DH). Materials and methods This randomized,…
View details →Negative / Null Result Report
Baek JS, Lokhande A, Neuenschwander D et al. · 2026 · Preprint
Purpose To investigate the relative efficacy of nine distinct visual field (VF) denoising artificial intelligence (AI) methods and a pathology-aware AI strategy to discourage over-correction of glaucomatous defects. Design Retrospective…
View details →Negative / Null Result ReportMedicine
van Lohuizen Q, Fransen SJ, Yiasemis G et al. · 2026 · European radiology
Objectives To determine whether AI-reconstructed prostate MRI at reduced acquisition times maintains prostate cancer (PCa) detection performance comparable to conventional scans. Materials and methods This multicenter, retrospective,…
View details →Negative / Null Result ReportMedicine
Akay T, Arslan RS · 2026 · Scientific reports
Patients with deep perianal abscess (DPA) and transsphincteric fistula typically require incision and drainage as emergency treatment. However, recurrent abscesses and fistulas are common. This study aimed to evaluate the impact of…
View details →Negative / Null Result ReportMedicine
Verhulst E, Ten Broek R, Bislenghi G et al. · 2026 · Techniques in coloproctology
Postoperative intraabdominal adhesions remain one of the most common and clinically significant complications following abdominal and pelvic surgery. Adhesions contribute to adhesive small bowel obstruction (aSBO), chronic abdominal pain,…
View details →Negative / Null Result Report
Murray CS, Marx L, Aluru N et al. · 2026 · Preprint
Ocean Alkalinity Enhancement (OAE) is a marine carbon dioxide removal (mCDR) strategy that involves adding alkaline substances to surface waters to enhance CO 2 uptake and storage. The dispersal of alkaline materials such as sodium…
View details →Negative / Null Result ReportMedicine
Ichie K, Asomugha A, Okafor I · 2026 · BMC neuroscience
Background Parkinson's disease (PD) is a progressive neurodegenerative disorder strongly associated with dopaminergic neuronal degeneration and alpha-synuclein pathology. Paraquat (PQ) has been implicated in Parkinsonian neurodegeneration;…
View details →Negative / Null Result ReportMedicine
Somerville E, Bollinger RM, Haxton M et al. · 2026 · OTJR : occupation, participation and health
Interventions to address polypharmacy and improve adherence are insufficient for community-dwelling older adults. To examine the feasibility, acceptability, and preliminary efficacy of a tailored medication management intervention (TIMM)…
View details →Negative / Null Result ReportMedicine
Hsieh YC, Lu WY, Chen YL et al. · 2026 · BMC ophthalmology
Background Selective laser trabeculoplasty (SLT) is a widely accepted treatment for primary open-angle glaucoma (POAG), but its role in primary angle-closure glaucoma (PACG) remains less defined. This study aimed to evaluate the short-term…
View details →Negative / Null Result Report
Liu W, Guo C, Ding W et al. · 2026 · Preprint
Background Postpartum asthenia, characterized by severe fatigue, sleep disturbances, and physiological stress, lacks effective targeted interventions. Ergothioneine (EGT) is a unique, naturally occurring antioxidant that actively…
View details →Negative / Null Result ReportMedicine
Verbo A, Verbo I · 2026 · Langenbeck's archives of surgery
Background Enhanced Recovery After Surgery (ERAS) protocols are widely implemented in colorectal surgery to improve postoperative recovery and reduce hospital stay. However, their impact on postoperative morbidity in elderly and clinically…
View details →Negative / Null Result ReportMedicine
Maiorca C, Tramontano D, Di Costanzo A et al. · 2026 · Internal and emergency medicine
Residual cardiovascular risk persists in many patients despite optimal control of established factors such as low-density lipoprotein cholesterol (LDL-C), blood pressure and glycaemia. Mounting evidence indicates that hypertriglyceridemia…
View details →Negative / Null Result ReportMedicine
Osorio Oliveros AV, Velasco Jaramillo JA, Alejo-Martínez H et al. · 2026 · Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Purpose To implement a continuous improvement cycle aimed at identifying and reducing radiation exposure incidents in patients undergoing PET-CT scans. Methods A comparative quasi-experimental study was conducted within a nuclear medicine…
View details →Negative / Null Result Report
Ortiz BM, Orozco SM, Dueñas LL et al. · 2026 · Preprint
Abstract Major depressive disorder (MDD) has increased in recent years, affecting 16.1% of the adult population nationwide. Currently, there are pharmacological and psychological treatments that have a 67% remission rate for depressive…
View details →Negative / Null Result ReportOpen accessMedicine
Schalch TO, Ando-Suguimoto ES, Ferreira BS et al. · 2026 · Clinical oral investigations
Objectives The aim of this study was to compare the effectiveness of two antimicrobial photodynamic therapy (aPDT) protocols using different methylene blue formulations in the treatment of initial pericoronitis. The research question was…
View details →Negative / Null Result ReportMedicine
Scampoli A, Governatori L, Solimeo A et al. · 2026 · Retina (Philadelphia, Pa.)
Purpose To evaluate whether baseline glycosylated hemoglobin (HbA1C) levels play a predictive role in faricimab loading phase outcomes. In addition, the authors assessed the efficacy of faricimab loading phase for diabetic macular edema…
View details →Negative / Null Result ReportMedicine
Pajina B, Leurcharusmee P · 2026 · Minerva anestesiologica
Background The anterior quadratus lumborum (QL) block provides effective post-cesarean delivery analgesia, but the optimal local anesthetic (LA) volume remains unknown. This is critical for balancing efficacy and safety in pregnant…
View details →Negative / Null Result Report
Shalash Al Maliky WK, Hasan Mohammed J, Dh Hazim M · 2026 · Preprint
Background Green synthesis of silver nanoparticles (AgNPs) using plant extracts has gained increasing attention as an environmentally friendly alternative to conventional chemical methods. Salix alba L contains bioactive phytochemicals…
View details →Negative / Null Result ReportMedicine
Koubek CT, Aghaee MA · 2026 · Journal of economic entomology
Lygus hesperus Knight (Hemiptera: Miridae) is a major pest of California strawberries, where feeding injury from nymphs and adults leads to fruit deformation and economic losses. Management relies heavily on insecticides, with supplemental…
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