20,227 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Bajwa MA, Lim J, Num YJ et al. · 2025 · Preprint
Abstract Objective : This study aims to analyze common radiographic parameters in adolescent idiopathic scoliosis (AIS) patients undergoing posterior spinal fusion (PSF) and determine their role in postoperative shoulder imbalance. Methods…
View details →Tepe D, Deligozoglu D, Baskan C et al. · 2026 · Journal of pediatric endocrinology & metabolism : JPEM
Objectives Although Graves' orbitopathy (GO) in childhood is generally considered milder than in adults, data regarding its clinical course and relationship with thyroid autoimmunity remain limited. This study aimed to evaluate the…
View details →White DE, Ghani U, Pedersen M et al. · 2025 · Journal of neuroengineering and rehabilitation
Background Unilateral nostril breathing (UNB) has a history linked to ancient yogic traditions where it is believed to affect both physical and mental states however the mechanism(s) by which this technique potentially influences brain…
View details →Köçer MS, Yıldız MK, Akgün BM et al. · 2026 · Preprint
Abstract Learning through play provides children with meaningful and lasting knowledge while fostering empathy, social responsibility, and cooperation. In disaster education, where vital life skills are addressed, game-based approaches…
View details →Houska N, McCaw N, Meneses EC et al. · 2026 · Journal of cardiothoracic and vascular anesthesia
Objectives To describe thrombotic outcomes associated with Factor Eight Inhibitor Bypassing Activity (FEIBA) exposure in neonates and infants undergoing cardiac surgery with cardiopulmonary bypass (CPB), including the Norwood procedure.…
View details →Almuashi H, AbuMostafa A · 2026 · Quintessence international (Berlin, Germany : 1985)
Objective The management of pain in dental procedures is crucial, as local anesthetic injections may induce patient anxiety and discomfort. Various techniques including Vibraject and Dentapen have been devised to alleviate injection…
View details →Veli-Quispe D, Urquizo-Prado S, Cesare-Ariza E et al. · 2026 · Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Background Cerebrovascular disease remains a leading cause of mortality worldwide. In Peru, evidence on recent mortality trends and regional disparities is limited. Objective To evaluate temporal trends and regional disparities in…
View details →Qin LG, Camarda ND, Kasetty VM et al. · 2026 · Journal of vitreoretinal diseases
Purpose: To investigate the effect of intravitreal (IVT) aflibercept injection monotherapy on retinal ischemia in eyes with severe proliferative diabetic retinopathy (PDR) that underwent pars plana vitrectomy (PPV) without panretinal…
View details →Li DY, Kim S, Javed S et al. · 2026 · Regional anesthesia and pain medicine
Background Methadone is commonly used as an alternative to other opioids for managing cancer-related pain. High-dose methadone, primarily in opioid dependence treatment, has been associated with QTc prolongation and dangerous arrhythmias.…
View details →Švajger U, Kolar M, Pompe B et al. · 2026 · Cartilage
ObjectiveUmbilical cord-derived mesenchymal stromal cells (UC-MSCs) are a promising treatment for knee osteoarthritis (KOA). This study aimed to (1) characterize early synovial fluid biomarker changes after intra-articular UC-MSCs therapy…
View details →Ramachandran I, Rajesh AT, Elumalai P · 2026 · Fish physiology and biochemistry
The current study aimed to ascertain the growth, antioxidant capacity, intestinal architecture, digestive enzyme activity, and disease resistance of S. agalactiae of Nile tilapia (Oreochromis niloticus) fed a diet enriched with…
View details →Rocco C, Larrouy-Maumus G, Wissuwa M et al. · 2026 · Preprint
1 Summary Zinc (Zn) deficiency limits rice productivity and poses a risk to human health, particularly in populations reliant on rice-based diets. Although rice germplasm exhibits wide variation in Zn-deficiency tolerance, the underlying…
View details →Kaba Ö, Tanatar A, Koç R et al. · 2026 · Jornal de pediatria
Objectives Colchicine is an essential component of familial Mediterranean fever (FMF) treatment. It is suggested that it may affect vitamin B 12 levels by affecting intestinal absorption. This research focused on examining the impact of…
View details →Kim S, Kim JH, Shin JY et al. · 2026 · Age and ageing
Background Depression is common in older adults, who are also at elevated risk of bleeding due to age-related physiological changes and comorbidities. Concerns have been raised regarding potential bleeding risk from concomitant use of…
View details →Wang R, Dai P, Deng X et al. · 2026 · Journal of thoracic disease
Background Thymoma is an uncommon cancer of the thymus and postoperative radiotherapy (PORT) is often considered for selected patients with high-risk or locally advanced thymoma after resection. The effect of PORT on overall survival (OS)…
View details →Bolton A · 2026 · Preprint
Abstract While the ecological effects of internal combustion engines are well documented, especially in susceptible arctic areas like Svalbard, effects on specific genera of plants are largely neglected. The Saxifraga genus was selected…
View details →Au YE, Baskaran R, Li JY et al. · 2026 · Preprint
Abstract Background The ability to appraise and apply research is fundamental to the practice of evidence-based medicine (EBM). Despite the General Medical Council’s (GMC) mandate for United Kingdom (UK) medical graduates to integrate…
View details →Patel M, Schwartz K, Schenk M et al. · 2026 · Orthopaedic journal of sports medicine
Background Ulnar collateral ligament (UCL) reconstruction (UCLR) of the elbow is common in throwing athletes and reliably allows return to play. The literature supports stress imaging of the elbow to evaluate the integrity of the UCL. The…
View details →Kumar P, Gordon A, Fisher E et al. · 2026 · The Australian & New Zealand journal of obstetrics & gynaecology
Background Routine third trimester ultrasound scans have been introduced in several maternity centres to increase detection of fetal growth disorders and improve perinatal outcomes. Aims To assess changes in obstetric and neonatal outcomes…
View details →Kasowanjete P, Dhilip Kumar SS, Houreld N · 2026 · Lasers in medical science
The phosphatidylinositol 3-kinase (PI3K), protein kinase B (AKT), mammalian target of rapamycin (mTOR) (PI3K/AKT/mTOR) pathway regulates cell survival, proliferation, and the synthesis of protein. Photobiomodulation (PBM) stimulates…
View details →Shannon ES, Sparks SA, McNaughton LR et al. · 2026 · European journal of applied physiology
PURPOSE: Hydrogen cation (H+) accumulation is exacerbated in hypoxia. Sodium bicarbonate (NaHCO3) ingestion can reduce fatigue associated with high-intensity exercise performance by counteracting H+ ion accumulation. The present study…
View details →Aziz F, Waseem M, Asghar Z et al. · 2026 · Preprint
Abstract Air pollution is a major public health crisis in Pakistan, driven by rapid urbanization, industrial expansion, agricultural burning, and inadequate monitoring infrastructure. This study evaluates five major pollutants inlcuding…
View details →SAKDAVONG J, SEBBAG A · 2026 · Preprint
Abstract Rapid advancements in Generative AI enable the synthesis of photorealistic pedagogical agents, yet their impact on human information processing remains debated. While Social Agency Theory predicts benefits from social priming,…
View details →Alsaffar SF, Khaleel HM · 2025 · Preprint
Background Polycystic ovarian syndrome (PCOS) is a hormonal, metabolic disorder in women of reproductive age. It can be induced by genetic, immunological, and environmental determinants. The main pathophysiology of PCOS, is…
View details →Shin E, Kim M, Soo TJ et al. · 2026 · Preprint
ABSTRACT To resolve discrepancies in the literature regarding the association between Alzheimer’s disease (AD) and Biondi body (BB) amyloid in choroid plexus epithelial cells (CPECs), we investigated postmortem hippocampal paraffin blocks…
View details →Ni J, Yan Y, Zhang L · 2026 · Preprint
Abstract Background: Growing recognition has established rare diseases as a public health priority. With over 20 million rare disease patients in China, establishing a robust medical security system is crucial for advancing the Healthy…
View details →Choo TH, Galfalvy HC, Keilp JG et al. · 2026 · Journal of affective disorders
Depression and its severe outcomes, suicidal ideation and behavior, are exacerbated by stress. A broad literature links dysregulation of the hypothalamic-pituitary-adrenocortical (HPA) stress response system to depression, suicidal…
View details →Guedes Marques M, Maia P, Martins A et al. · 2026 · The journal of vascular access
Background The most common causes of early primary failures of a vascular access (VA) is related to small caliber vessels. Weight gain between dialyses expands both extracellular and blood volume, which may lead to rises in intravascular…
View details →Medina-Valdebenito D, Espinoza-Palavicino T, Terán-Mendoza O et al. · 2026 · Journal of aging and health
ObjectivesThis study examined the influence of hearing status and loneliness on verbal fluency trajectories in adults aged 60 years and older, assessing their contributions to baseline performance and longitudinal change over…
View details →Géczi R, Géczi G, Tóth L · 2026 · Sports (Basel, Switzerland)
The aim of this study was to examine the relative contribution of physical performance, executive functions, and competitive anxiety to competitive success in junior tennis players. A total of 39 national-level junior athletes (20 males,…
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