Negative / Null Result ReportMedicine
Yamamoto J, Nakamura K, Hayama H et al. · 2026 · Cardiology
Whether the mortality impact of ischemic stroke and major bleeding differs across left ventricular ejection fraction (LVEF) categories in patients hospitalized for acute heart failure (AHF) with atrial fibrillation (AF) remains uncertain.…
View details →Negative / Null Result ReportMedicine
Ricketts TA, Krivoshey R, Santos-Garrido J et al. · 2026 · Journal of speech, language, and hearing research : JSLHR
Purpose The purpose of this study was to evaluate the effects of loudspeaker configuration and relative dialogue-to-background sound levels on subjective ratings of speech understanding and sound quality of recorded media for listeners…
View details →Negative / Null Result ReportMedicine
Jee J, Zhang J, Lavery JA et al. · 2026 · Cancer discovery
Real-world data suggest that SARS-CoV-2 mRNA vaccines, administered within 100 days of immune checkpoint inhibitor (ICI) treatment ("peri-ICI vaccination"), may improve ICI effectiveness through synergistic immune priming. In an…
View details →Negative / Null Result ReportMedicine
Maynart V, Menezes P, Batista C et al. · 2026 · Ear and hearing
Abstractobjectives The purpose of this experiment was to determine the effects of sequential sounds on cortical auditory evoked potentials and to investigate temporal masking. The study tested the hypotheses that forward masking reduces…
View details →Negative / Null Result ReportMedicine
Li X, Zhang Y, Chen S · 2026 · Journal of counseling psychology
This study examined how clients' outcome expectations (OE; belief about positive outcome of counseling session) was associated with working alliance and symptom relief longitudinally in a sample of Chinese beginning therapist trainees and…
View details →Negative / Null Result ReportMedicine
Peters EM, Quadri A, Aziz S et al. · 2026 · Journal of affective disorders
The purpose of this study was to examine the effects of two patient-level factors, episode duration and severity, on placebo response in antidepressant clinical trials. To do this we conducted a secondary analysis of seven 8-week,…
View details →Negative / Null Result ReportMedicine
Yan Z, Tian Y, Huang Y et al. · 2026 · Psychopathology
Introduction Distraction response style, neuroticism, and parental conflict have been linked to rumination in adolescents with subthreshold depression. However, whether these associations differ by gender remains unclear. Methods This…
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Su C, Lu T · 2026 · Preprint
Background Heart failure (HF) and body mass index (BMI) share substantial genetic architecture, which may lead genetically informed target discovery to preferentially identify adiposity-related pathways. We sought to identify circulating…
View details →Negative / Null Result ReportMedicine
Howard L, Hawn S, Pitchford KD et al. · 2026 · Behavioral sciences (Basel, Switzerland)
The denial, concealment, or omission of disordered eating behaviors has received limited attention in the eating disorder literature, partly due to the lack of reliable and valid measures. This study re-examined the factor structure of the…
View details →Negative / Null Result ReportMedicine
Li Y, Chen R, Hou C et al. · 2026 · Medicine
We performed a 2-step Mendelian randomization (MR) study to investigate the associations of Fms-related tyrosine kinase 3 ligand (FLT3L) and phosphate levels with the risk of hypertrophic cardiomyopathy (HCM). Genetic instruments for 75…
View details →Negative / Null Result ReportMedicine
Aghaalikhani M, Rostami Abusaidi S, Azimi F et al. · 2026 · Journal of medical case reports
Background Osteosarcoma is the most common primary malignant bone tumor, typically affecting adolescents and young adults. While its development is often associated with rapid bone growth and genetic factors, the potential link between…
View details →Negative / Null Result ReportMedicine
Liu Y, Wei M · 2026 · Journal of the Optical Society of America. A, Optics, image science, and vision
Color matching functions (CMFs) play important roles in color specification, characterization, and reproduction. Though the CIE 1931 2° CMFs are widely used in practice, its well-known weaknesses and poor performance have motivated great…
View details →Negative / Null Result ReportMedicine
Rahal D · 2026 · Journal of health psychology
Although social support is related to better health, research is mixed regarding how social support relates to physiological systems including the parasympathetic nervous system. The present study assessed whether perceived parental and…
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shakeel h · 2026 · Preprint
Abstract Correct ligand-site assignment is a prerequisite for interpreting molecular dynamics simulations of non-ATP kinase ligands. In computational chemistry and structure-based drug discovery, apparent ligand stability does not by…
View details →Negative / Null Result ReportMedicine
Li YB, Zheng ZW, Zuo M · 2026 · BMC gastroenterology
Background Total body water (TBW) is an important indicator of fluid homeostasis and is closely related to various metabolic and chronic diseases. However, the relationship between TBW and gastrointestinal symptoms (stomach or intestinal…
View details →Negative / Null Result ReportMedicine
Liu P, Dang C, Liu J et al. · 2026 · Current medicinal chemistry
Introduction This study aimed to investigate the causal relationship and biological mechanism between oral contraceptives (OCs) and adverse pregnancy outcomes using Mendelian randomization (MR) methods. Methods We conducted a drug-target…
View details →Negative / Null Result ReportMedicine
Zadrożny Ł, Orlańska A, Ponto-Wolska M et al. · 2026 · European journal of dentistry
Objective This article aims to evaluate dental students' experiences, perceptions, and expectations related to training with virtual reality-based haptic simulators (VRHS) introduced into the preclinical and clinical dental curriculum.…
View details →Negative / Null Result ReportMedicine
Schmidt G, Dietsche S, Stoll K et al. · 2026 · Sexual & reproductive healthcare : official journal of the Swedish Association of Midwives
Objective To evaluate the psychometric properties of the German Birth Beliefs Scale (G-BBS) in a large sample of pregnant women in Germany, and its potential utility for women-centred birth counselling, and respectful maternity care.…
View details →Negative / Null Result Report
Wang M, Bai B, Yin T et al. · 2026 · Preprint
Abstract This study applied a two‑sample bidirectional Mendelian randomization (MR) design using genetic summary statistics from the FinnGen R9 database to examine the causal link between genetic predisposition to antidepressant treatment…
View details →Negative / Null Result Report
Figureau T, Priolo D, Sleegers WWA et al. · 2025 · Preprint
Cognitive dissonance, a fundamental psychological process involving inconsistent cognitions causing discomfort, may vary across cultures. These variations could be attributed to differences in the way people define themselves, known as…
View details →Negative / Null Result ReportMedicine
Saengsin K, Jirattikanwong N, Wongyikul P et al. · 2026 · Journal of clinical medicine
Background/Objectives : Post-extubation stridor (PES) is common in pediatric critical care and may contribute to extubation failure, particularly in children with heart disease. Prophylactic corticosteroids are frequently used before…
View details →Negative / Null Result Report
Figureau T, Priolo D, Sleegers WWA et al. · 2026 · Preprint
Cognitive dissonance, traditionally conceptualized as a fundamental psychological process involving discomfort from inconsistent cognitions, may vary across cultures. These variations could be attributed to self-construal, or how…
View details →Negative / Null Result ReportMedicine
Espeche W, Minetto J, Cerri G et al. · 2026 · Hypertension research : official journal of the Japanese Society of Hypertension
Hypertensive disorders of pregnancy are a leading cause of maternal-fetal morbidity and mortality, with preeclampsia representing a major contributor to adverse outcomes. Ambulatory blood pressure monitoring (ABPM) has improved risk…
View details →Negative / Null Result ReportMedicine
Vollam S, Roman C, Santos M et al. · 2026 · JMIR medical informatics
Background Many studies have evaluated the use of wearable monitoring systems to improve patient safety in hospital. Although some have demonstrated effects on intensive care admissions, there remains little evidence of impact on patient…
View details →Negative / Null Result Report
Appiah KN, Sharma N, Adu N et al. · 2026 · Preprint
Abstract Background: Anthracycline-based chemotherapy produces progressive functional decline and cardiotoxicity in adults with cancer. Physical activity interventions may attenuate these effects, yet evidence across multiple domains…
View details →Negative / Null Result ReportMedicine
Qin X, Fan L, Tang Y et al. · 2026 · Archives of gynecology and obstetrics
Purpose The potential adverse effects of repeated freezing and thawing processes on embryos remain controversial. This study aimed to investigate the impact of repeated embryo cryopreservation by comparing preimplantation genetic testing…
View details →Negative / Null Result Report
Kang B · 2026 · Preprint
Abstract Background: Major depressive disorder (MDD) is highly polygenic, yet translating genome-wide association study (GWAS) findings into therapeutics remains challenging. Using PGC MDD2025, we integrated gene-level mapping, brain TWAS,…
View details →Negative / Null Result ReportMedicine
Koczur K, Blukacz M, Galbarczyk A et al. · 2026 · American journal of human biology : the official journal of the Human Biology Council
Objectives Microbiota of the urogenital tract is crucial for women's reproductive and sexual health and is largely dominated by Lactobacillus strains. A reduction of these bacteria within the vaginal microbial community has been linked to…
View details →Negative / Null Result Report
Karl V, Beck D, Dall'Aglio L et al. · 2026 · Preprint
Background: Adolescence is a developmental period involving ongoing white matter (WM) maturation and rising risk for psychopathology. This risk is particularly elevated among youth whose parents have mental health problems. Methods:…
View details →Negative / Null Result ReportMedicine
Pongdee T · 2026 · Current allergy and asthma reports
PURPOSE OF REVIEW: Recent strategies to treat nonadvanced SM have focused on targeted therapies to inhibit mast cell activation and/or proliferation. Several investigational approaches are being explored to treat nonadvanced SM in this…
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