19,854 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Beaulieu A, Saint-Georges C, Hagbarth I et al. · 2026 · Scientific reports
General movements (GMs) refer to infants’ spontaneous motor activities before the emergence of voluntary motor activity. Abnormal GMs in neonates have been regarded as a marker of poor neurodevelopmental outcomes, with preliminary findings…
View details →Iljazi A, Sørensen MS, Winther-Jensen M et al. · 2024 · Acta orthopaedica
Background and purpose Dislocation is a severe complication following total hip arthroplasty (THA). Hip precautions have been recommended in the initial postoperative period but evidence supporting this practice is limited. We therefore…
View details →Klüwer B, Gleditsch R, Rydland KM et al. · 2024 · Vaccine
Aims To explore public confidence in influenza vaccination through the use of attitudinal indicators, and study whether educational attainment is related to attitudes towards influenza vaccination. Methods Confidence in influenza…
View details →Jang S, Gwak HS, Joo J et al. · 2024 · Acta neurochirurgica
Purpose This study aimed to evaluate the symptomatic response and side effects of ventriculolumbar perfusion (VLP) methotrexate chemotherapy with a low perfusion rate in patients with leptomeningeal metastasis. Methods Patients in a…
View details →Chen J, Hou S, Feng R et al. · 2023 · Preprint
CRISPR homing gene drive is a potent technology with considerable potential for managing populations of medically and agriculturally significant insects. It induces a bias in the inheritance of the drive allele in progeny, rapidly…
View details →nema sk, ramsubramani P, S s · 2023 · Preprint
Abstract Background Transmembrane proteins of the Wnt family and receptor tyrosine kinase (ROR1 and ROR2) suppression or overexpression has been implicated in the causation of cancers. We determined the expression of ROR2 among patients of…
View details →Mauz JB, Rieland H, Berliner D et al. · 2024 · Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Background & aims Considerate patient selection is vital to ensure the best possible outcomes after transjugular intrahepatic portosystemic shunt (TIPS) insertion. However, data regarding the impact of intrapulmonary vascular dilatations…
View details →Seaman RW Jr, Shariatzadeh N, Salinas KA et al. · 2026 · Drug and alcohol dependence
Background Stimulant-opioid co-use has surged in the United States, with methamphetamine use among people who use opioids increasing 82.6 % from 2015 to 2017. This trend contributes to rising overdose deaths, marking a "fourth wave" of the…
View details →Lilley A, Chiapponi C, Prosperi A et al. · 2026 · Vaccines
Background/Objectives : Influenza A viruses cause seasonal epidemics of respiratory infections in humans, the severity of which can be mitigated by influenza vaccine use. Influenza A viruses circulating in pigs continue to pose a pandemic…
View details →Ng MK, Mastrokostas PG, Rodriguez AN et al. · 2025 · Journal of craniovertebral junction & spine
Context Semaglutide, a glucagon-like protein-1 receptor agonist used in diabetes and obesity management, has demonstrated perioperative benefits in other surgical populations. However, its role in spine surgery remains unclear. Aims This…
View details →Pilas LB, Gur O, Berger G · 2023 · The Israel Medical Association journal : IMAJ
Background In the past decade, numerous new imaging and laboratory tests have been implemented that significantly contribute to improved medical diagnostic capabilities. However, inappropriate utilization, which occurs on a large scale,…
View details →Jones CMP, Lin CC, Zadro J et al. · 2024 · Brazilian journal of physical therapy
Background The Brief Pain Inventory-Interference Subscale (BPI-IS) is a subscale of the BPI assessment tool developed to rapidly assess the impact of a person's pain on their function. It is uncertain whether it has one or two factors, and…
View details →Risi M, Greco G, Masciocchi S et al. · 2024 · Journal of neurology
Background Live cell-based assay (LCBA) is the gold standard for MOG-IgG detection, and fixed CBA (FCBA) is a widely used commercial alternative. Recent criteria attributed a diagnostic value to MOG-IgG titration with both LCBA and FCBA,…
View details →Ilmakunnas I, Sten-Gahmberg S · 2026 · Journal of aging & social policy
Flexible partial retirement schemes are intended to give individuals the opportunity to reduce working hours before moving into full retirement, the expectation being that the reduced workload will contribute to postponed old-age…
View details →Soufi R, Salamzadeh J, Alavi Darazam I et al. · 2025 · Iranian journal of pharmaceutical research : IJPR
Background Vancomycin is commonly used in intensive care units (ICUs), but its optimal dosage in patients with acute kidney injury (AKI) remains uncertain. This study aimed to evaluate vancomycin's pharmacokinetic and pharmacodynamic…
View details →Ullal SD, Thomas AG, Acharya SD et al. · 2026 · Pharmacology research & perspectives
Epilepsy is a common neurologic disorder; its incidence in childhood is 2.5 per 1000 children. Levetiracetam (LEV) is an antiepileptic drug with a broad spectrum of action used in localized and generalized epilepsies in both adults and…
View details →Hawkey AB, Fan R, Nwachukwu K et al. · 2025 · Neurotoxicology and teratology
Neurotoxic risks in the environment come from many toxicants, which are often found together in complex mixtures. However, nearly all experimental studies evaluate one chemical at a time. Neurobehavioral effects of developmental exposure…
View details →Jacover A, Beller T, Mahamid N et al. · 2025 · Annals of surgical oncology
Introduction Neoadjuvant therapy (NT) is generally preferred over upfront surgery for borderline resectable pancreatic ductal adenocarcinoma (BR-PDAC), but many patients fail to reach surgical resection. This study evaluates real-world…
View details →Tanisaka Y, Ryozawa S, Mizuide M et al. · 2025 · Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society
Endoscopic sphincterotomy (EST) is challenging for patients with surgically altered anatomy (SAA). The blades of conventional sphincterotomes designed for SAA do not always face the correct direction of EST. We aimed to evaluate the…
View details →Sandby K, Magkos F, Chabanova E et al. · 2024 · Clinical nutrition (Edinburgh, Scotland)
Background & aims In recent years, epidemiological studies have reported links between the consumption of fermented dairy products, such as yogurt, and health; however, evidence from human intervention trials is scarce and inconsistent. We…
View details →Buck AN, Fleiner T, Rosskothen-Kuhl N et al. · 2026 · Trends in hearing
It is widely known that users of cochlear implants (CIs) often show deficits in binaural hearing. In particular, interaural time difference (ITD) discrimination tends to be substantially worse in CI users. However, only very few studies…
View details →Chen Y, Gao J, Wang X et al. · 2024 · Frontiers in nutrition
Background Evidence from observational studies on the association between folate and metabolic dysfunction-associated steatotic liver disease (MASLD) is conflicting. Aims This study aimed to investigate the association between serum folate…
View details →Castillo L, Berrozpe-Villabona C, Miserachs-García S et al. · 2024 · Acta ophthalmologica
Purpose The role of the choroid in Leber hereditary optic neuropathy (LHON) remains unclear. The literature is scarce, with conflicting results and lacks axial length measurements. Therefore, we aimed to analyse the choriocapillaris (CC)…
View details →Ding L, Reiher M · 2026 · Journal of chemical theory and computation
Neural quantum states (NQS) are a promising ansatz for solving many-body quantum problems due to their inherent expressiveness. Yet this expressiveness can only be harnessed efficiently for treating identical particles if the suitable…
View details →Brunekreef J · 2024 · Journal of imaging informatics in medicine
The cited article reports on a convolutional neural network trained to predict response to neoadjuvant chemotherapy from pre-treatment breast MRI scans. The proposed algorithm attains impressive performance on the test dataset with a mean…
View details →Loos E, Van Stiphout L, Lucieer F et al. · 2025 · Scientific reports
Little is known about the evolution of vestibular dysfunction and health-related quality of life in bilateral vestibulopathy patients over time. Furthermore, it is unknown whether etiology influences the evolution. A retrospective study…
View details →Ahmadi Somaghian S, Pajouhi N, Dezfoulian O et al. · 2024 · Archives of physiology and biochemistry
Objective Improvement of cell survival is essential for achieving better clinical outcomes in stem cell therapy. We investigated the effects of hyperoxic pre-treatment (HP) on the viability of human adipose stromal stem cells (ASCs).…
View details →Liao C, Nie J, Xu XJ et al. · 2024 · Leukemia & lymphoma
Two hundred and thirty-one acute lymphoblastic leukemia (ALL) children with 1376 high-dose methotrexate (HD-MTX) courses (3-5 g/m 2 ) were enrolled to analyze the influence of the plasma MTX concentration ( C MTX ) in ALL. The 24-h target…
View details →Chen W, Yoshida S, Fujii Y · 2026 · Cancer reports (Hoboken, N.J.)
Background Androgen receptor signaling inhibitors (ARSI) combined with androgen deprivation therapy (ADT) have demonstrated significant survival benefits in metastatic hormone-sensitive prostate cancer (mHSPC) in several clinical trials.…
View details →Findlay MC, Tenhoeve S, Alt J et al. · 2024 · Neurosurgery
Background and objective Cushing disease (CD) affects mortality and quality of life along with limited long-term remission, underscoring the need to better identify recurrence risk. The identification of surgical or imaging predictors for…
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