Browse the failure-mode index

Effect of Low-Temperature Conditioning of Excess Dairy Sewage Sludge with the Use of Solidified Carbon Dioxide on the Efficiency of Methane Fermentation

Joanna Kazimierowicz, Izabela Bartkowska, Maria Walery · 2020 · Energies

This study aimed to determine the effect of the low-temperature conditioning of excess dairy sewage sludge using solidified carbon dioxide on the efficiency of methane fermentation. An increase in the solidified carbon dioxide to excess dairy sewage sludge volumetric ratio above 0.3 had no significant effect on chemical oxygen demand concentration in the dissolved phase. The highest chemical oxygen demand values, ranging from 490.6 ± 12.9 to 510.5 ± 28.5 mg·dm −3 , were determined at solidified carbon dioxide to excess dairy sewage sludge ratio ranging from 0.3 to 0.5. The low-temperature cond

Effects of selenium-enriched probiotics on growth performance, antioxidant capacity, intestinal health, and metabolism in mandarin fish (Siniperca chuatsi) juveniles

Fu liang, Ming Li, Meiling Yu et al. · 2026 · Aquaculture Reports

Abstracts: This study investigated the effects of selenium-enriched Bacillus subtilis on the growth performance, antioxidant capacity, intestinal health, and metabolism of mandarin fish (Siniperca chuatsi) juveniles. The experiment included a control group (Y), a Bacillus subtilis group (BS), an inorganic selenium group (Se), and three groups with low, medium, and high concentrations of selenium-enriched B. subtilis (S1, S2, S3) in a 30-day feeding trial. The results showed that selenium-enriched B. subtilis had no significant effect on the final average body weight or specific growth rate of

Factors Influencing Off‑leash Dog Walking in Public Places

Michaela Sediva, Kristyna Holcova, Lenka Pillerova et al. · 2017 · Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis

Little is known about factors that influence owners’ decisions walking their dogs on or off a leash in public places. We examined the effect of the type of public place, dog’s age, sex and size, and human gender on off‑leash dog walking. Observations of 1850 dogs and their owners were made in streets and parks in Brno (Czech Republic). Multiple logistic regression analysis showed no significant effect of human gender on the frequency of unleashed dogs in streets and parks. Off‑leash dog walking was 2.8 times more likely in parks than in streets. Adult dogs were unleashed 1.9 times more likely

Internal cumulants for femtoscopy with fixed charged multiplicity

H. C. Eggers, B. Buschbeck · 2013 · arXiv

A detailed understanding of all effects and influences on higher-order correlations is essential. At low charged multiplicity, the effect of a nonpoissonian multiplicity distribution can significantly distort correlations. Evidently, the reference samples with respect to which correlations are measured should yield a null result in the absence of correlations. We show how the careful specification of desired properties necessarily leads to an average-of-multinomials reference sample. The resulting internal cumulants and their averaging over several multiplicities fulfil all requirements of cor

On the Casimir effect between superconductors

Giuseppe Bimonte · 2019 · arXiv

A recent experiment [R. A. Norte et al. Phys. Rev. Lett. {\bf 121}, 030405 (2018)] probed the variation of the Casimir force between two closely spaced thin Al films, as they transition into a superconducting state, observing a null result. We present here computations of the Casimir effect for superconductors, based on the Mattis-Bardeen formula for their optical response. We show that for the Al cavity used in the experiment the effect of the transition is over two hundred and fifty times smaller than the experimental sensitivity, in agreement with the observed null result. We demonstrate th

Use of a slow-release GnRH implant in an adult billy goat.

Demattio L, Fietz D, Schuler G et al. · 2024 · Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere

A 9.4 mg deslorelin slow-release implant was inserted into an adult, healthy billy goat to achieve temporary infertility and a reduction in sexual behavior. The implant was inserted in late autumn. No significant change in testis size was…

Evaluating the Effectiveness of Age Simulation Gloves.

Lüleci EH, Kedgley AE · 2026 · Human factors

ObjectiveThis study evaluated the effectiveness of age simulation gloves in replicating age-related declines in hand function.BackgroundCommercially available age simulation gloves are increasingly used. However, their ability to replicate…

Arago (1810): the first experimental result against the ether

Rafael Ferraro, Daniel M. Sforza · 2004 · arXiv

95 years before Special Relativity was born, Arago attempted to detect the absolute motion of the Earth by measuring the deflection of starlight passing through a prism fixed to the Earth. The null result of this experiment gave rise to the Fresnel's hypothesis of an ether partly dragged by a moving substance. In the context of Einstein's Relativity, the sole frame which is privileged in Arago's experiment is the proper frame of the prism, and the null result only says that Snell's law is valid in that frame. We revisit the history of this premature first evidence against the ether theory and

Engineering the second generation of growth factors and cytokines for regenerative medicine applications

Growth factors and cytokines have a great potential for regenerative medicine applications. Yet, most of these molecules have failed to show efficacy in humans or raised major safety concerns, due to high dosing and inappropriate delivery…

Testing the activitystat hypothesis

Physical activity has many health and psychological benefits, however many programs aimed at increasing physical activity have failed to show the expected results. This may be because when people increase their level of exercise, they…

Projection Measurement of the Maximally Entangled N-Photon State for a Demonstration of N-Photon de Broglie Wavelength

F. W. Sun, Z. Y. Ou, G. C. Guo · 2005 · arXiv

We construct a projection measurement process for the maximally entangled N-photon state (the NOON-state) with only linear optical elements and photodetectors. This measurement process will give null result for any N-photon state that is orthogonal to the NOON state. We examine the projection process in more detail for N=4 by applying it to a four-photon state from type-II parametric down-conversion. This demonstrates an orthogonal projection measurement with a null result. This null result corresponds to a dip in a generalized Hong-Ou-Mandel interferometer for four photons. We find that the d

Fluoroquinolones and the risk of aortic aneurysm or aortic dissection: evidence from a nationwide nested case-control study paralleled with matched experimental models.

Wesley CD, Strange JE, Holt A et al. · 2025 · European heart journal open

Aims Fluoroquinolones (FQ) have been associated with aortic aneurysm and aortic dissection (AA/AD) resulting in an official warning. Recently, large-scale epidemiological studies failed to confirm this. Methods and results The current…

Single-Cell and Plasma Proteomics Do Not Differentiate Patients With and Without SARS-CoV-2 Antigenemia in Convalescence in a Cohort of 100 Patients.

Pienkos S, Swank Z, Hamlin RE et al. · 2025 · Open forum infectious diseases

Plasma samples obtained approximately 3 ( n = 100) and 12 months ( n = 78) after acute SARS-CoV-2 infection were tested for S1, spike, and N antigens. There were no significant differences in plasma proteins or single-cell protein…

Association Between eHealth Literacy and Mental Health Literacy: Cross-Sectional Study.

Neter E, Youngmann R, Gruper N · 2025 · JMIR formative research

Unlabelled Associations between eHealth literacy and mental health literacy were examined; no significant association was identified between overall eHealth and mental health literacy and only weak associations between specific skills were…

Does Communication Effectiveness Assessed by Communication Scholars Correlate with Patient Perception of Clinician Empathy?

Ponce H, Cordero R, Tran J et al. · 2025 · Journal of patient experience

In a prior study, communication scholar ratings of clinician communication effectiveness did not correlate with perceived clinician empathy, which is one aspect of patient experience. We repeated the analysis with a different rating of…

Impact of subsequent immune checkpoint inhibitor treatment on overall survival with avelumab vs docetaxel in platinum-treated advanced NSCLC: Post hoc analyses from the phase 3 JAVELIN Lung 200 trial.

Park K, Özgüroğlu M, Vansteenkiste J et al. · 2021 · Lung cancer (Amsterdam, Netherlands)

Objectives The JAVELIN Lung 200 phase 3 trial did not meet its primary endpoint of improving overall survival (OS) with avelumab vs docetaxel in patients with platinum-treated PD-L1+ NSCLC. We report post hoc analyses assessing the effects…

Hemodynamic Effects of an Increased Midodrine Dosing Frequency.

Macielak SA, Vollmer NJ, Haddad NA et al. · 2021 · Critical care explorations

In practice, midodrine has been used to reduce IV vasopressor requirements and decrease ICU length of stay. However, recent publications have failed to show clinical success when midodrine was administered every 8 hours. One possible…

Outcomes of Patients With Reduced Left Ventricular Function Undergoing Left Atrial Appendage Occlusion.

Higgins AY, Huang CY, Zimmerman S et al. · 2026 · JACC. Clinical electrophysiology

Background Transcatheter left atrial appendage occlusion (LAAO) is an alternative treatment to prevent stroke in patients with atrial fibrillation. Patients with reduced left ventricular ejection fraction (LVEF) represent a particularly…

Estimating the Opportunity for Early Detection of Ovarian Cancer Using Individual-Patient Data from a Large Randomized Controlled Trial.

Ryser MD, Holloway ST, Morsomme R et al. · 2025 · Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Background The UK Collaborative Trial of Ovarian Cancer Screening did not detect a reduction in ovarian cancer mortality with either multimodal screening (MMS) or transvaginal ultrasound screening (USS) compared with no screening. The…

Cardiovascular Outcomes in Adults with Coronary Artery Disease and Obstructive Sleep Apnea with versus without Excessive Daytime Sleepiness in the RICCADSA Cinical Trial.

Eulenburg C, Celik Y, Redline S et al. · 2023 · Annals of the American Thoracic Society

Rationale: Recent randomized controlled trials did not show cardiovascular benefits of continuous positive airway pressure (CPAP) in adults with coronary artery disease (CAD) and obstructive sleep apnea (OSA) in intention-to-treat…

The Camden Coalition Care Management Program Improved Intermediate Care Coordination: A Randomized Controlled Trial.

Finkelstein A, Cantor JC, Gubb J et al. · 2024 · Health affairs (Project Hope)

When a randomized evaluation finds null results, it is important to understand why. We investigated two very different explanations for the finding from a randomized evaluation that the Camden Coalition's influential care management…

Intact reinforcement learning in healthy ageing

Lin W, Clarke AM, Pilz KS et al. · 2023 · Preprint

What does age in ageing? Results in reinforcement learning (RL) are mixed. Some studies found deteriorated performance in older participants compared to younger controls whereas other studies did not. Daniel et al. (2020) suggested that…

Testing the robustness of daily associations of affect with alcohol and cannabis use.

Dora J, Kuczynski AM, McCabe CJ et al. · 2026 · Journal of psychopathology and clinical science

Etiological models of alcohol and cannabis use disorders hypothesize that people are more likely to use substances when experiencing heightened negative affect, yet recent Ecological Momentary Assessment (EMA) studies found no evidence for…

Assessing treatment effects and publication bias across different specialties in medicine: a large empirical study of the Cochrane Database of Systematic Reviews

Schwab S, Giuachin K, Held L · 2020 · Preprint

Publication bias is a persisting problem in meta-analyses for evidence based medicine. As a consequence small studies with large treatment effects are more likely to be reported than studies with a null result which causes asymmetry. Here,…

Salt exposure disrupts memory retrieval in habituation and conditioned place preference in planaria (Dugesia japonica).

Tazumi T, Prados J, Urcelay GP · 2026 · Journal of comparative psychology (Washington, D.C. : 1983)

This study examined whether saline acts as an aversive stimulus for planarians and how it influences learning and memory. Using saline as an unconditioned stimulus, we first tested conditioned place avoidance. Saline did not support…

Can WIMP Spin Dependent Couplings explain DAMA data, in light of Null Results from Other Experiments?

Christopher Savage, Paolo Gondolo, Katherine Freese · 2004 · arXiv

We examine whether the annual modulation found by the DAMA dark matter experiment can be explained by Weakly Interacting Massive Particles (WIMPs), in light of new null results from other experiments. CDMS II has already ruled out most WIMP-nucleus spin-independent couplings as an explanation for DAMA data. Hence we here focus on spin-dependent (axial vector; SD) couplings of WIMPs to nuclei. We expand upon previous work by (i) considering the general case of coupling to both protons and neutrons and (ii) incorporating bounds from all existing experiments. We note the surprising fact that CMDS

Lights, Cameras, Action - The influence of lighting and camera position on walking and running kinematic measurements using Theia3D markerless motion capture.

Thomas A, Tucker CB, Lunn DE et al. · 2026 · Journal of biomechanics

Studies investigating the concurrent validity of markerless motion capture (MMC) systems for obtaining joint and segment kinematics have largely failed to consider the impact of ambient lighting and camera position, which can both affect…

Comparing the effects of commercial to open initial specimen diversion techniques on clinical outcomes and institutional costs.

Yang EH, Lopez C, Shay SL et al. · 2026 · Infection control and hospital epidemiology

The clinical outcomes associated with using commercial versus open ISDTs (initial specimen diverting techniques) remain unclear. This multicenter study showed that switching from the commercial to open ISDT did not change blood culture…

Simultaneous inhibition of PARP/AKT to intercept nascent BRCA1/2^mut breast tumors.

Wang L, Sardella BR, Aronson EK et al. · 2026 · NPJ breast cancer

We utilized the K14-Cre Brca1 f/f Tp53 f/f mouse model to investigate whether a pulse of PARP inhibitor (PARPi) ± an AKT inhibitor (AKTi) can prevent Brca1-related breast cancer. PARPi alone did not intercept or prevent tumor development.…

Registered Report: Can Agentic Black Women Get Ahead? An Experiment Revisited.

Liu CX, Blair BA, Tenney ER · 2026 · Psychological science

In 2012, Livingston et al. found that Black women were buffered against gender backlash; whether Black women were dominant or supportive toward an employee did not affect people's perceptions of them as leaders in an organization.…