20,227 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Zawar I, Zhu S, Quigg M et al. · 2026 · Brain communications
Epilepsy is a common comorbidity of Alzheimer's disease (AD) and related dementias (ADRD). Both epilepsy and ADRD affect the mesial temporal structures in volume and morphology. Nonetheless, mesial temporal shape and volume asymmetry…
View details →Xu L, Wang X, Meng X et al. · 2026 · Oral health & preventive dentistry
Purpose To explore the relationship between dental caries and non-alcoholic fatty liver disease (NAFLD) and its advanced stage of liver fibrosis, and to confirm causality by employing a bidirectional two-sample Mendelian Randomization (MR)…
View details →Popovici I, Carvajal MJ, Higgins T et al. · 2026 · The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG
Objectives While gender disparities in the US workforce have received substantial attention, income inequalities among subspecialty pharmacists remain understudied. This study aimed to develop a professional profile of pediatric…
View details →Stępień S, Morawiec ML, Smycz-Kubańska M et al. · 2026 · Frontiers in oncology
Ovarian cancer (OC) is a major clinical problem in gynaecological oncology, characterised by difficulties in early diagnosis, which contributes to the high mortality rate from OC. Therefore, the search for new biological markers continues,…
View details →Espinoza-Ríos J, Ruiz-Cortez R, Santiago B et al. · 2026 · BMC gastroenterology
Background Upper gastrointestinal bleeding (UGIB) remains one of the most common emergencies in gastroenterology, with mortality rates reaching 14% in some settings. Despite advances in management, mortality has remained relatively…
View details →Shinde N, Warad VG, Potkar S et al. · 2026 · Cureus
Introduction Type 2 diabetes mellitus (T2DM) is a growing global health concern. Emerging evidence suggests that vitamin D and calcium play an important role in glucose metabolism and insulin function. The present study aimed to compare…
View details →Spasić M, Todorović K, Živković N et al. · 2026 · Journal of functional biomaterials
Impacted mandibular third molars present a common challenge in oral surgery, often associated with postoperative complications such as delayed healing and periodontal defects; therefore, optimizing adjunctive therapies is clinically…
View details →Zhao FY, Yue LP, Ho YS et al. · 2026 · Nature and science of sleep
Background and aims Insomnia during pregnancy is potentially associated with adverse outcomes, including gestational diabetes mellitus, pre-eclampsia, cesarean delivery, preterm birth, and depression. This study aimed to synthesize…
View details →Onaghise J, A DK · 2026 · Preprint
Abstract Background Rural working-age adults in West Africa face a compounding burden of rising non-communicable disease prevalence, specifically hypertension and diabetes, and severe structural barriers to accessing formal healthcare.…
View details →Champion KA, AlDosari M · 2026 · Journal of dental education
Purpose Few evidence-based tools exist to support holistic review in dental school admissions. The Holistic Admissions Assessment Rubric (HAAR) was developed to score applicant data from the Associated American Dental Schools Application…
View details →Zhou Y, Qin S, Ma Y · 2026 · Clinical and experimental hypertension (New York, N.Y. : 1993)
Background Essential hypertension (EH) remains a leading modifiable risk factor for cardiovascular morbidity and mortality worldwide. Electroacupuncture (EA), combining traditional acupuncture with pulsed electrical stimulation at specific…
View details →Sun Y, Yang X, Zhu Q et al. · 2026 · Drug design, development and therapy
Autoimmune thyroiditis (AIT) is a chronic immune-mediated thyroid disorder characterized by lymphocytic infiltration, follicular epithelial injury, autoantibody production, and variable progression to thyroid dysfunction. Because current…
View details →Aubret A, Triesch J · 2026 · Developmental science
There is strong and diverse evidence for mental rotation (MR) abilities in adults. However, current evidence for MR in children rests on just a few behavioral paradigms adapted from the adult literature. Here, we leverage recent…
View details →Sugita H, Sato MT, Yamaji N et al. · 2026 · The Cochrane database of systematic reviews
Rationale Non-communicable diseases (NCDs), such as hypertension, diabetes, and asthma, require continuous medication management. However, medication adherence remains suboptimal. Telepharmacy-defined as pharmacist-led care delivered…
View details →Champion S, Bilton R, Gordon S · 2026 · Australasian journal on ageing
Objectives This study evaluated the outcomes for individuals who completed an Innovator Training Program (ITP) funded by the Commonwealth Government of Australia and delivered by Aged Care Research & Industry Innovation Australia (ARIIA).…
View details →Larvie DY, Güitrón Leal CE, Venkatramanan S et al. · 2026 · The Cochrane database of systematic reviews
Rationale Vitamin B 12 deficiency is an important public health problem in children, and has been associated with anaemia and impaired growth, cognition, and development. Vitamin B 12 deficiency may develop in children due to lower content…
View details →Shu W, Zhou Y, Sun E et al. · 2026 · Journal of medical Internet research
Background Embodied intelligence-artificial intelligence instantiated in physical or virtual bodies that can perceive, communicate, and interact with users and their environments-has been increasingly applied in health care. However, the…
View details →Gazit N, Ben-Gal G, Eliashar R · 2026 · JMIR medical education
Background Assessment of technical aptitude, cognitive abilities, and personality characteristics is important in selecting candidates for surgical training. Currently, the selection of surgical training candidates does not systematically…
View details →Du Y, Xu Z, Wen T et al. · 2026 · Diabetes, metabolic syndrome and obesity : targets and therapy
Purpose The care of diabetic foot ulcers (DFU) continues to be a notable clinical challenge. The efficacy and safety of stem cell therapies versus conventional treatments for DFU are debated. Cross-sectional analyses of meta-analyses…
View details →Zhang Y, Wu Z · 2026 · Frontiers in public health
Background Digital technologies in oncology require patients and health workers to possess adequate electronic health literacy (eHealth literacy). Yet, the extent to which this literacy influences cancer-specific insights, ranging from…
View details →Hou YN, Gubili J, Mao JJ · 2026 · Seminars in radiation oncology
Studies show that patients with cancer use herbal products more often than the general population. Lowering the risk of disease recurrence, symptom control, and improving quality of life are often the reasons cited for such use. However, a…
View details →Kyei EF, Kyei GK, Forson MM et al. · 2026 · Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing
Aim To examine nurse practitioner opioid prescribing authority across three countries, analyzing safety outcomes, workforce distribution patterns, access equity, and service to vulnerable populations using integrated nursing policy and…
View details →Tafuri MG, Monda V, La Marra M et al. · 2026 · Nutrients
Background/Objectives: Sport participation and nutrition are increasingly recognized as key determinants of cognitive function and academic achievement in student populations. However, the biological mechanisms underpinning these…
View details →Leahy TP, Keenan C, Robertshaw E et al. · 2026 · Value in health regional issues
Objectives Growing reliance on single-arm trials (SATs) is driving increased real-world external control arm (RW-ECA) use in health technology assessment submissions. However, concerns over residual confounding and unmeasured bias often…
View details →Fuller S, Dent N, Ohly H et al. · 2026 · Preprint
Abstract Abstract Background: Infants under six months of age in low‑income countries (LICs) face high morbidity and mortality, driven by prematurity, low birthweight (LBW), malnutrition, infection, and environmental enteric dysfunction.…
View details →Lebâcle C, Kassab D, Faix A et al. · 2026 · The French journal of urology
Objectives To provide a focused secondary synthesis and critical clinical interpretation of the AFU/SFMS evidence base on phytotherapies and complementary therapies for erectile dysfunction (ED). Evidence acquisition The parent AFU/SFMS…
View details →Maisch P, Hamidi Madani M, Koziarz A et al. · 2026 · The Cochrane database of systematic reviews
Rationale Disease recurrence and progression remain major challenges in the treatment of non-muscle invasive bladder cancer (NMIBC). Blue light-enhanced transurethral resection of bladder cancer (TURBT) is an approach to improve staging…
View details →Shao F, Han Z, Su Q et al. · 2026 · JMIR serious games
Background Serious games (SGs) have emerged as a promising tool in nursing education, providing interactive learning environments for clinical simulation, skill development, and feedback. These games enhance knowledge, clinical reasoning,…
View details →Cai M, Lai W, Peng W et al. · 2026 · BMC oral health
Background Diabetes Mellitus (DM) is a global metabolic disorder affecting 537 million adults. Periodontitis stands as its sixth major complication and shares a bidirectional relationship with diabetes, whereby each condition exacerbates…
View details →Angelucci F, Cerman J, Amlerova J et al. · 2026 · Degenerative neurological and neuromuscular disease
Spermidine is a naturally occurring polyamine involved in multiple cellular processes, including growth regulation, protein translation, and autophagy. Increasing attention has been devoted to its potential neuroprotective effects,…
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