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Browse the failure-mode index

20,227 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

The Effect of Transcranial Near-infrared Laser Therapy on Chronic Ischemic Stroke Patients: A Randomized, Single-blind, Sham-controlled Trial.

Hassan M, Al Balah O, Hegazy A et al. · 2026 · Journal of the Saudi Heart Association

Background Transcranial photobiomodulation (TPBM) using near-infrared (NIR) light is a novel, non-invasive neuromodulation strategy with potential to enhance neurorecovery. While preclinical studies are promising, clinical evidence in…

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Negative / Null Result ReportOpen accessMedicine

Sneezing in response to naturalistic bright light exposure.

Bickerstaff L, Trinkl J, Munkwitz S et al. · 2025 · F1000Research

Background The photic sneeze reflex (PSR) is a common but underexplored phenomenon where bright light triggers sneezing, affecting ~30% of the population. This study aimed to characterise the light conditions inducing PSR. Methods One male…

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Negative / Null Result ReportOpen accessMedicine

Effect of <i>Echinacea purpurea</i> on cytokine gene expression (IL10, IL1β, TNFα, IFNγ), telomere length, lipid peroxidation, and nitric oxide in broilers reared at high altitude.

Bahadoran S, Vaeznia S, Hassanpour H · 2026 · Veterinary and animal science

This study evaluated the effects of dietary Echinacea purpurea supplementation on immune regulation, oxidative stress, and cellular aging in broiler chickens reared at high altitude (2100 m). One hundred and eight day-old male Ross 308…

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Negative / Null Result ReportOpen accessMedicine

Achievement (not effort) makes people feel entitled to rewards.

Cusimano C, Kim J, Wong J · 2025 · Proceedings of the National Academy of Sciences of the United States of America

It is common to say that people feel entitled to rewards-they think they have earned or deserve them-based on their effort and achievement. However, effort and achievement draw on different principles to justify reward. They can also…

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Negative / Null Result ReportOpen accessMedicine

Preoperative Systemic Inflammatory Marker Profile in Surgically Treated Intradural Spinal Tumors: A Retrospective Cohort Study.

Kırkgeçit M, Türkoğlu H, Yüzbaşı MF et al. · 2026 · Medicina (Kaunas, Lithuania)

Background and Objectives : We aimed to determine whether preoperative systemic inflammatory markers derived from complete blood count differ between patients with intradural spinal tumors and healthy controls, and whether any such…

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Negative / Null Result ReportOpen accessMedicine

Rare germline genetic variation in PAX8 transcription factor binding sites and susceptibility to epithelial ovarian cancer.

Ezquina SAM, Jones M, Dicks E et al. · 2025 · American journal of epidemiology

Common genetic variation throughout the genome and rare coding variants identified to date explain about half of the inherited genetic component of epithelial ovarian cancer risk. It is likely that rare variation in the noncoding genome…

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Negative / Null Result ReportOpen accessMedicine

Exploring the correlation between academic achievement and self-regulated learning on critical thinking in undergraduate medical students.

Farhan MA, Makkiyah FA, Hadiwiardjo YH et al. · 2025 · BMC medical education

Objective This study examines the relationship among medical students' academic achievement, self-regulated learning, and critical thinking ability. Methods This study employed a cross-sectional analytical design involving 120 medical…

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Negative / Null Result ReportOpen accessMedicine

Prophylactic wiring vs. non-wiring in hip arthroplasty: finite element and cadaveric analysis of proximal femur biomechanics.

Sangroungrai A, Atipiboonsin V, Sukhonthamarn K et al. · 2025 · Arthroplasty (London, England)

Background Intraoperative periprosthetic femur fracture is a serious complication in hip arthroplasty, affecting patient outcomes. This study explored the biomechanical properties of the proximal femur, specifically comparing prophylactic…

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Negative / Null Result ReportOpen accessMedicine

Theta Transcranial Alternating Current Stimulation Over the Dorsomedial Prefrontal Cortex Does Not Enhance Long-Term Memory.

Chitic D, Zdravkov KS, Dounavi V et al. · 2026 · The European journal of neuroscience

Long-term memory (LTM) has been associated with neural oscillation in the theta (3-8 Hz) range. Although previous studies have suggested that the dorsomedial prefrontal cortex (dmPFC) is a core region for LTM retrieval, causal evidence is…

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