19,854 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Xiong Y, Huang J, Wu Y et al. · 2026 · Renal failure
Physical activity (PA) is of great importance for peritoneal dialysis (PD) patients with sarcopenia. However, the optimal PA dose for sarcopenia in PD patients remains unclear. This study adopted a cross-sectional design and enrolled PD…
View details →Luo M, Wang Y, Wang Y et al. · 2026 · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Objective The optimal interpregnancy interval (IPI) for preventing hypertensive disorders of pregnancy (HDP) remains unclear, and whether this association is modified by maternal baseline characteristics has not been well established. This…
View details →Revilla-León M, Gómez-Polo M, Barmak AB et al. · 2026 · The Journal of prosthetic dentistry
Statement of problem As experience with intraoral scanners (IOSs) and scientific evidence has grown, factors compromising IOS accuracy have been identified. Limited interdental space between tooth preparations lead to the bridge scanning…
View details →Seale L, Bates N, Tumin D et al. · 2026 · European journal of obstetrics, gynecology, and reproductive biology
Objective To examine the association between age at menarche and polycystic ovary syndrome (PCOS) diagnosis among US women aged 20-49 years. Study design Our retrospective cross-sectional analysis used data from the 2022-2023 National…
View details →Wang X, Zhang R, Chai W et al. · 2026 · Medicine
The incidence of IgA nephropathy (IgAN) is increasing, and some observational studies reported the potential correlation of polycystic ovary syndrome (PCOS) with the risk of IgAN. We performed a bidirectional Mendelian randomization…
View details →Gonzalez W, Isla J, Barba D et al. · 2026 · Journal of ISAKOS : joint disorders & orthopaedic sports medicine
Background Anterior tibial translation (ATT) measured on magnetic resonance imaging (MRI) is a reproducible marker of anterior cruciate ligament (ACL) deficiency. However, its longitudinal evolution after ACL reconstruction (ACLR) and its…
View details →Bax EA, Colyn W, Bellemans J et al. · 2026 · Osteoarthritis and cartilage open
Objectives This study investigated the association between alpha angles of the hip and tibial genu varum in a healthy population with equal male-to-female distribution. It also examined sex-based differences, explored the impact of sports…
View details →GUILLEN SANCHEZ JS, Saenz Tolay M, Cabanillas Chirinos L et al. · 2026 · Preprint
Background: The rising consumption of ultra-processed foods (UPFs) is a global concern, given their poor nutritional quality and the presence of multiple additives that may pose health risks when consumed in excess. Young populations are…
View details →Motoji Y, Kitamura T, Naito N et al. · 2026 · Interdisciplinary cardiovascular and thoracic surgery
Objectives This study aimed to investigate changes in haematoma thickness (HT) and the maximum ascending aortic diameter (MAD) early after onset and their association with in-hospital disease progression in type A intramural haematoma…
View details →Mannen R, Maeda K, Inoue T et al. · 2026 · Journal of frailty, sarcopenia and falls
Objectives Osteosarcopenia is characterized by the coexistence of sarcopenia and osteoporosis. This comorbid condition is thought to negatively affect functional outcomes. In this study, we investigated the negative impact of…
View details →Othus M, Truong TG, Sharon E et al. · 2026 · JCO oncology practice
Purpose Multiple reports have suggested that receiving immunotherapy infusions earlier in the day is associated with improved outcomes, including longer overall survival (OS) and lower toxicity rates. However, the definition of early…
View details →Molla HT, Gashu D, Chowanadisai W et al. · 2026 · Preprint
Background: Etiologies of neural tube defects (NTDs) are multifactorial. Genetic, epigenetic and environmental factors may contribute to their reported variation in prevalence across the globe. Ethiopia has among the highest reported NTD…
View details →Tabeta A, Tsutsumi Y, Hoshi H et al. · 2026 · BMC surgery
Background Perforated peptic ulcer is a critical emergency disease requiring surgery, and postoperative intra-abdominal abscess (IAA), an organ/space surgical site infection (SSI), is a common complication. Intraoperative irrigation is a…
View details →Hsu JZ, Gu K, Nguyen B et al. · 2026 · The Annals of otology, rhinology, and laryngology
Objective Estrogen has been found to impact cochlear blood flow and auditory function, but epidemiological studies on menopause and hearing are inconsistent. This study investigates the associations of menopause, its age at onset,…
View details →Nandurkar A · 2026 · Preprint
Abstract Background Hearing loss in adults is a leading problem worldwide. Provision of the whole spectrum of aural rehabilitation (AR) services to adults with acquired hearing loss has been acknowledged as a global challenge, due to…
View details →Al-Mujahid M, shomais A, Sinan Y et al. · 2026 · Preprint
Abstract Background Health-related quality of life (HRQoL) is a crucial patient-centered outcome in the management of chronic diseases, particularly cardiovascular disease (CVD). Objective To assess the health-related quality of life and…
View details →Keel E, Kalimeris S, Adams M et al. · 2026 · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Background Infants born before 32 weeks of gestation are at high risk of developing intraventricular hemorrhage (IVH), which is associated with significant mortality and morbidity as well as long-term neurodevelopmental impairment. There…
View details →Maharjan U, Kauppila JH · 2026 · Surgical oncology
Background Previous studies on hospital volume of gastrectomy and mortality in gastric cancer are conflicting, with some suggesting improved short-term outcomes in higher volume hospitals and fewer studies demonstrating consistent findings…
View details →Molla HT, Gashu D, Stoecker B et al. · 2026 · Genes
Background Etiologies of neural tube defects (NTDs) are multifactorial. Genetic, epigenetic and environmental factors may contribute to their reported variation in prevalence across the globe. Ethiopia has among the highest reported NTD…
View details →Cheng V, Sayre EC, Amiri N et al. · 2026 · Journal of autoimmunity
Objectives While targeted synthetic disease-modifying antirheumatic drugs (tsDMARDs) have advanced autoimmune disease management, the paucity of perinatal safety data limits evidence-based decision-making in pregnancy. We aimed to…
View details →Berto LG, da Silva CL, Durante MV et al. · 2026 · Pediatric surgery international
Objective Acute appendicitis is the leading cause of abdominal surgery. This study evaluated outcomes of transumbilical single-incision laparoscopic appendectomy (TSILA) compared with conventional laparoscopy and open surgery. Methods A…
View details →Alogaili MH, Hussein ZA, Alsallami AA et al. · 2026 · BMC medical education
Background Time management involves using time efficiently to complete specific tasks and the grade point average (GPA) is a summary statistic that represents students' average academic performance over a specific period. Both the…
View details →Ji J, Sun CL, Dale W et al. · 2026 · GeroScience
Among older adults with early breast cancer, the risk of chemotoxicity can vary widely despite similar chronological age. Here, we evaluated whether epigenetic indicators of biological age can stratify the risk of chemotoxicity in this…
View details →Götz N, Völkerer A, Hofer H et al. · 2026 · Scandinavian journal of gastroenterology
Background Barrett's esophagus (BE) is a premalignant condition associated with gastroesophageal reflux disease (GERD) and an increased risk of esophageal adenocarcinoma (EAC). While Helicobacter pylori ( H. pylori ) has been proposed as a…
View details →Benvenuti L, Digennaro V, Colangelo A et al. · 2026 · European journal of orthopaedic surgery & traumatology : orthopedie traumatologie
Purpose The influence of polyethylene (PE) insert thickness on long-term implant survival after total knee arthroplasty (TKA) remains controversial. Thicker PE inserts are generally reserved for cases in which adequate ligament balance…
View details →Garcia-Ruiz MP, Torres-Bautista RM, Lopez-Franco MD et al. · 2026 · Journal of clinical medicine
Objectives: The general objective of the study was to analyze the influence of sociodemographic factors and care and hygiene practices on the appearance of Incontinence-Associated Dermatitis (IAD). The specific objectives were to identify…
View details →Wu W, Fan Y · 2026 · Medicine
Anesthesia is indispensable to modern surgical practice and clinical care; however, its potential impact on neurodevelopment and behavioral outcomes has raised growing concerns. Discrepancies among previous studies may partly arise from…
View details →Dorofte L, Davidsson S, Carlsson J et al. · 2026 · Cancers
Background Penile squamous cell carcinoma is an uncommon neoplasm that arises via two carcinogenic pathways, one linked to HPV infection and the other to chronic inflammation and p53 alterations. Objective/methods We assessed the…
View details →Devlin H, Bedi R · 2026 · British dental journal
Aims To assess whether area-level deprivation predicts the population-adjusted distribution of National Health Service (NHS) dental practices within a socioeconomically diverse English local authority.Methods Analysis of dental practice…
View details →Parveen A, Jatoi R, Haya A et al. · 2026 · Cureus
Background and aim Postpartum depression (PPD) is a mental health condition that adversely affects both maternal and infant well-being. Kangaroo Mother Care (KMC), involving skin-to-skin contact and exclusive breastfeeding, has shown…
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