20,227 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Brown HS, Wall B, Mears SC et al. · 2024 · Geriatric orthopaedic surgery & rehabilitation
Introduction 1 mm cerclage cables have been introduced that can be placed under plates and hold reduction of periprosthetic femur fractures (PPFFx) around total hip arthroplasty (THA). Their utilization remains controversial due to the…
View details →Lima MR, Paiva MS, Maltês S et al. · 2025 · Current problems in cardiology
Background Atrial septal defects (ASD) often go unrecognized until very late in life. The impact of ASD closure on life expectancy in elderly patients remains unclear. This study compares the survival of patients≥65-years who underwent ASD…
View details →Nishikimi M, Ohshimo S, Nobayashi K et al. · 2026 · Critical care (London, England)
Background Neither the magnitude nor the timing of mean arterial pressure (MAP) increase after norepinephrine (NE) initiation is well defined, leaving clinicians without clear criteria for adequate starting doses. This study aimed to…
View details →Hviid CVB, Rasmussen NH, Røikjer J · 2025 · Acta diabetologica
Background Objective and easily applicable biomarkers for diabetic polyneuropathy (DPN) are warranted. Circulating nerve-specific proteins have emerged as valuable biomarkers for central nervous system disease but few of these have been…
View details →Zhao P, Zhao S, Huang C et al. · 2025 · Hematological oncology
Polatuzumab vedotin plus R-CHP (Pola-R-CHP) is approved as a new standard first-line therapy for diffuse large B-cell lymphoma (DLBCL) based on the POLARIX trial. However, real-world data on its efficacy and safety in unselected patients…
View details →Reindl N, Seitz S, Schleier M et al. · 2025 · Pediatric surgery international
Purpose Postoperative scarring remains a major concern for patients and parents following repair of congenital abdominal wall defects. This study evaluated perceptions of postoperative scars in children after omphalocele or gastroschisis…
View details →Thomas P, Kerrey B, Edmunds K et al. · 2024 · Pediatric emergency care
Background The lower clinical exposure of Pediatric Emergency Medicine (PEM) fellows to critical procedures may impede skill acquisition. We sought to determine the tracheal intubation learning curve of PEM fellows during training and…
View details →Pelzer F, Leisge K, Kaczmarek C et al. · 2025 · Scientific reports
We often perform motor tasks in front of other people, and this may help or hinder our performances. Previous research mainly focused on changes in motor performance, and less is known about spectator influences on performance predictions.…
View details →Moore E, Webb E, Sasaki R et al. · 2025 · Preprint
Numerous studies highlight alterations in motor cortical neurophysiology after mild traumatic brain injury (mTBI). In contrast, understanding of effects in cognitive brain areas, which potentially underpin more impactful effects of injury,…
View details →Panzer S, Hofstetter N, Schreiber M et al. · 2026 · Experimental brain research
The present study examined if a daytime nap of 90 min can further improve skill memory afforded by observation and physical practice. Moreover, we determined if a 'nap' benefit was restricted to a particular representational form (spatial…
View details →McNaughton DT, Mara P, Jones MP · 2024 · Australian health review : a publication of the Australian Hospital Association
Objective There is a need to undertake more proactive and in-depth analyses of general practice accreditation processes. Two areas that have been highlighted as areas of potential inconsistency are the self-assessment and surveyor…
View details →Fowler TE, Bloomquist RF, James JN · 2025 · BMC oral health
Background The incidence of fascial space infections of the head and neck has long been suggested to correlate with weather patterns, though objective evidence is inconsistent, and a causative effect is difficult to prove. One issue in the…
View details →Viskupič F, Wiltse DL · 2025 · PLOS global public health
It is possible that the negative attitudes toward COVID-19 vaccination developed by some people, such as self-identified Republicans, might spill over toward other vaccines. We conducted a survey experiment to investigate if mentioning…
View details →Meade MJ, Jensen S, Ju X et al. · 2024 · International orthodontics
Objective The aim of the present study was to evaluate the quality and readability of content contained within clear aligner therapy (CAT) informed consent forms. Methods CAT informed consent forms were identified via an online search. The…
View details →Chhaya D, Gress M, Raja A et al. · 2024 · International journal of environmental research and public health
The objective of this study is to investigate the potential mutagenic effects of the exposure of mice to aerosols produced from the component liquids of an electronic nicotine delivery system (ENDS). The use of electronic cigarettes…
View details →Xu L, Yu D, Li F et al. · 2024 · Preprint
Abstract Objective To determine the efficacy and tolerability of Anlotinib plus temozolomide (TMZ) as a first-line treatment for recurrent malignant glioma (rMG). Methods A total of 30 eligible patients who relapsed from the standard…
View details →Maier F, Luttenberger I, Dreisoerner A et al. · 2026 · Stress and health : journal of the International Society for the Investigation of Stress
Chronic stress has well-documented adverse effects on physical and psychological health. Beyond contributing to the development of fatigue, its impact is intensified by social stressors such as loneliness, making the development of…
View details →Turner TJ, Brun P, Gruber R et al. · 2024 · Preprint
Tolebrutinib is a covalent BTK inhibitor designed and selected for potency and CNS exposure to optimize impact on BTK-dependent signaling in CNS-resident cells. We applied a translational approach to evaluate three BTK inhibitors in Phase…
View details →Al-Khalaifah H, Al-Nasser A, Al-Surrayai T · 2025 · Life (Basel, Switzerland)
There is growing interest in adding marine algae to poultry feed rations. The aim of the present study is to examine the effect of various inclusions of Sargassum sp., Gracilaria sp., and Spirulina sp. on productive performance, serum…
View details →Zamora Veliz HY, Paredes Cabanillas RY, Gomez Trejo JE et al. · 2025 · Cureus
Introduction Intestinal anastomotic leakage is a serious postoperative complication associated with high morbidity and mortality. Although acute-phase reactants such as procalcitonin (PCT) and CRP have been proposed as early biomarkers,…
View details →Halačová M, Mieresová M, Kubele J et al. · 2026 · Pharmacological reports : PR
BACKGROUND: Beta-lactams are the cornerstone of therapy for the treatment of the most serious infections in the intensive care unit (ICU) setting. However, individualization of dosing remains challenging because pharmacokinetics are highly…
View details →Dumont JR, Sheppard PAS, Fodor C et al. · 2025 · Genes, brain, and behavior
Alzheimer's disease is a debilitating neurodegenerative condition characterized by amyloid beta plaques and tau neurofibrillary tangles, which leads to progressive cognitive decline. Several new mouse models of fast amyloid deposition have…
View details →Langevin P, Frémont P, Fait P et al. · 2024 · Disability and rehabilitation
Purpose The objective of this study was to compare the effects of an in-clinic cervicovestibular rehabilitation program (education, home exercises, manual techniques, sub-symptom threshold aerobic exercise [STAE] program) to a similar…
View details →Schleifenbaum L, Stern J, Driebe JC et al. · 2024 · Hormones and behavior
Previous research on the endogenous effects of ovarian hormones on motivational states in women has focused on sexual motivation. The Motivational Priority Shifts Hypothesis has a broader scope. It predicts a shift from somatic to…
View details →Fumagalli D, Sonik R, De Vitis LA et al. · 2024 · Gynecologic oncology
Background Advanced epithelial ovarian cancer (OC) patients often present with malnutrition; however, the ideal nutritional evaluation tool is unclear. We aimed to evaluate the role of preoperative albumin, Prognostic Nutritional Index…
View details →Figueiredo RR, de Azevedo AA, Figueiredo GMR et al. · 2026 · Brazilian journal of otorhinolaryngology
Objectives COVID-19 is a respiratory disease caused by the coronavirus SARS-CoV-2. Previous studies reported cases of tinnitus following COVID infection, most of them mild and with similar characteristics to other forms of tinnitus. Our…
View details →Bello RJ, Palleiko BA, Kennedy K et al. · 2024 · Surgical oncology
Background Pain management following mastectomy is a significant challenge often requiring opioids. Nonopioid pain management utilizing nerve blocks has been shown in other fields to reduce postoperative opioid use and may be effective for…
View details →Pan L, Kaku Y, Tolentino JE et al. · 2025 · Frontiers in microbiology
In the 21st century, three severe human coronavirus infections have occurred. One of them is the Middle East respiratory syndrome coronavirus (MERS-CoV), a merbecovirus belonging to the family Coronaviridae , is a human pathogenic…
View details →Khan M, Yousaf H, Naqqash M et al. · 2025 · Cureus
Introduction There is limited local data comparing the outcomes of core decompression and fibular strut grafting in early-stage avascular necrosis (AVN) of the hip. International findings may not be directly applicable due to…
View details →Yaşar NF, Badak B, Salış M et al. · 2024 · Revista da Associacao Medica Brasileira (1992)
Objective Endogenous melatonin is produced from tryptophan which is an essential amino acid. Besides its role in the regulation of sleep patterns, melatonin has anti-inflammatory effects. In this case-control study, we aimed to compare…
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