Negative / Null Result ReportOpen accessDiseases of the musculoskeletal system
Xingtao Ge, Xinghua Ge, Chen Wang et al. · 2022 · BMC Musculoskeletal Disorders
Abstract Background A safe and effective technique for anterolateral portal placement in elbow arthroscopy is significant. We compared the outcomes of patients who underwent elbow arthroscopy using different ultrasound-assisted techniques. Methods From May 2016 to June 2021 a retrospective analysis on all patients who underwent elbow arthroscopy in our department was performed. Patients were separated into three groups: non-ultrasound; preoperative ultrasound; and intraoperative ultrasound. The minimum follow-up period was 1 year. Nerve injuries, visual analog scale (VAS), Mayo elbow-performan
View details →Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Maryam Sharifi, Shahrbanoo Oryan, Alireza Komaki et al. · 2023 · IBRO Neuroscience Reports
There is growing evidence that the hippocampus comprises diverse neural circuits that exhibit longitudinal variation in their properties, however, the intermediate region of the hippocampus has received comparatively little attention. Therefore, this study was designed to compared short- and long-term synaptic plasticity between the dorsal and intermediate regions of the hippocampus in normal and PTZ-kindled rats. Short-term plasticity was assessed by measuring the ratio of field excitatory postsynaptic potentials’ (fEPSPs) slope in response to paired-pulse stimulation at three different inter
View details →Negative / Null Result ReportOpen accessAgriculture
Preetaman Bajwa, Rupinder Saini, Sukhbir Singh et al. · 2025 · Agrosystems, Geosciences & Environment
Abstract Industrial hemp is receiving attention for its numerous benefits, particularly in the fiber industry. Weed competition is a primary concern for hemp cultivation, causing reduced yields and inferior‐quality fiber. However, little is known about herbicide application in hemp since a limited range of herbicides are available for hemp production. During 2023, this study evaluated the effect of different post‐emergence herbicides applied at early and late growth stages to optimize weed suppression and minimize crop injury in hemp under semiarid conditions. A randomized complete block desig
View details →Negative / Null Result ReportOpen accessScience (General)
Shenkute Goshme, Tadiws Asfaw, Chekol Demiss et al. · 2021 · Heliyon
The frozen bull semen straws were gathered from three specifically chosen locations in the North Shewa Zone, namely Baso, Chacha, and Debre-Birhan town, and the laboratory work was carried out at the Debre Birhan agricultural research center. The researchers wanted to see how different thawing methods affected the mass motility of frozen bull sperm. The thawing protocols used for mass motility evaluation were 37 °C for 30 s, 35 °C for 40 s, 40 °C for 40 s, body temperature using a hand for 15 s and body temperature using a hand for 30 s by using a water bath. The mass motility of the frozen bu
View details →Negative / Null Result ReportOpen accessMedicine (General)
Madeleine M. Southey, Trent Rees, Margaret Rolfe et al. · 2019 · Addiction Science & Clinical Practice
Abstract Background Residential opioid rehabilitation aims to improve the mental health and quality of life of opioid users through abstinence and residential program participation. This study aimed to determine the depression, anxiety, stress and quality of life amongst maintenance to abstinence (MTA) program residents. Secondary study aims were to assess the personal characteristics of MTA clients, addiction and risk taking behaviours, factors associated with program completion, as well as to assess the reliable change in participants’ mental health and quality of life on exit. Methods Retro
View details →Negative / Null Result ReportOpen accessScience
Shan Zhang, Shu Wu, Yiru Shen et al. · 2020 · Royal Society Open Science
Magnetic Fe3O4 nanoparticles (Fe3O4-NPs) have been widely investigated for their biomedical applications. The main purpose of this study was to evaluate the cytotoxic effects of different sizes of Fe3O4-NPs in chicken macrophage cells (HD11). Experimental groups based on three sizes of Fe3O4-NPs (60, 120 and 250 nm) were created, and the Fe3O4-NPs were added to the cells at different doses according to the experimental group. The cell activity, oxidative index (malondialdehyde (MDA), superoxide dismutase (SOD) and reactive oxygen species (ROS)), apoptosis and pro-inflammatory cytokine secretio
View details →Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Waqas Akhtar, Charles Butcher, Andrew Morley‐Smith et al. · 2022 · ESC Heart Failure
Abstract Aims We present a single‐centre retrospective experience using oral milrinone in patients with a left ventricular assist device (LVAD) and concurrent refractory right ventricular failure. Methods and results All patients implanted with LVAD between January 2013 and July 2021 from a high‐volume advanced heart failure service were reviewed. Eight patients were initiated on oral milrinone during this period. Oral milrinone was started 1.5 [inter‐quartile range (IQR) 1–2.3] years after LVAD implantation and continued for 1.2 (IQR 0.5–2.8) years. Therapeutic milrinone levels were achieved
View details →Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Dan Zhu, Zhenzhen Fan, Fujun Cheng et al. · 2022 · Brain Sciences
Objectives: To investigate the efficacy and safety of an improved ultrasound-guided pulsed radiofrequency (PRF) and nerve block (NB) for patients with pudendal neuralgia (PN). Methods: This retrospective analysis included 88 adults with PN treated in the Pain Department of Southwest Hospital from November 2011 to June 2021, with treatment including NB ( n = 40) and PRF ( n = 48). The primary outcome variable was pain severity, measured by a standardized visual analog scale (VAS). VAS values were collected at 1, 3, 7, and 14 days and 1 and 3 months after patients were treated with NB or PRF. Re
View details →Negative / Null Result ReportOpen accessMedicine
CHEN Zhu, LIU Yan, GAO Li-hua, CHEN Bu-you, TANG Ai-hua, LIU Jun · 2021 · Jichu yixue yu linchuang
Objective To evaluate the efficacy and safety of apatinib in the treatment of metastatic colorectal cancer (mCRC). Methods Sixty-five patients with mCRC treated with apatinib were enrolled in this study for retrospective analysis. The factors affecting the recent effective, progression-free survival (PFS) and adverse reactions were evaluated. Results The disease control rate in 63 evaluable patients was 69.9%. The median PFS for patients received first-line, second-line, and third-line and above apatinib treatment were 9.3 months, 5.8 months, and 3.3 months, respectively(P＜0.001). The PFS in t
View details →Negative / Null Result ReportOpen accessOphthalmology
Lin Y, Luo S, Lu Q et al. · 2024 · Clinical Ophthalmology
Ye Lin, Shuke Luo, Qiang Lu, Xueke Pan Department of Ophthalmology, The Second People’s Hospital of Foshan, Foshan, Guangdong Province, People’s Republic of ChinaCorrespondence: Shuke Luo, Department of Ophthalmology, The Second People’s Hospital of Foshan, Foshan, Guangdong Province, 528000, People’s Republic of China, Tel +86 13679830510, Email 542377993@qq.comPurpose: To investigate the psychological changes in patients pre and post implantable collamer lens (ICL, EVO) implantation surgery in the posterior chamber.Patients and methods: Self-rating anxiety scale (SAS) and self-rating depress
View details →Negative / Null Result ReportOpen accessMedical emergencies. Critical care. Intensive care. First aid
V. A. Shmyrev, D. N. Ponomarev, P. P. Perovsky et al. · 2014 · Общая реаниматология
Objective: to comparatively evaluate the perioperative clinical period in patients operated on via miniinvasive access and median sternotomy.Subjects and methods. A retrospective analysis included all patients who had undergone correction of mitral valve defect with or without tricuspid valve correction and atrial ablation. 121 and 112 patients were operated on through miniinvasive access (a study group) and median sternothomy (a control group), respectively.Results. The duration (median [25; 75 percentiles] of aortic occlusion in the study group (89 [71; 120] min) was significantly longer tha
View details →Negative / Null Result ReportOpen accessScience
Livhuwani E. Nephale, Ngonidzashe A.G. Moyo, Mmaditshaba M. Rapatsa-Malatji · 2024 · Scientific African
An 8-week feeding trial was conducted to evaluate the effect of Alates termite (Macrotermes falciger) based diet in a herbivorous (Oreochromis mossambicus) and an opportunistic predator (Clarias gariepinus). Five diets were formulated to replace fishmeal at 0, 10, 30, 50, and 70 % and were denoted D1, D2, D3, D4, and D5, respectively. Clarias gariepinus sub-adults (209.24 ± 2.41 g/fish) were stocked at 5 fish per tank in recirculating fibreglass tanks (400 L) in triplicates. Oreochromis mossambicus juveniles (7.4 ± 4.78 g/fish) were randomly stocked at 10 fish per tank in recirculating fibregl
View details →Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Lina Jans, Jan Brynhildsen, Joar Hofgaard et al. · 2025 · Infectious Agents and Cancer
Abstract Background Users of intrauterine devices (IUDs) have been found to have a lower incidence of cervical cancer in meta-analyses, but these studies have not been able to examine the influence of IUD type. The aim of this study is to investigate the incidence of de novo high-risk human papillomavirus (HPV) infections in relation to the reported use of contraceptive methods, with special regard to different types of IUDs. Methods A sample of participants in the national screening program for cervical cancer (n = 11,702) with a negative HPV test in 2017–2018 were included. Their subsequent
View details →Negative / Null Result ReportOpen accessGynecology and obstetrics
Guodong Zhang, Jijun Li, Jun Tang et al. · 2019 · BMC Pregnancy and Childbirth
Abstract Background The aim of this study was to assess the feasibility, safety and outcome of the embolization of non-gonadal collateral supplying gestational sac (GS) in addition to uterine artery embolization (UAE), followed by hysteroscopic curettage for the management of cesarean scar pregnancy (CSP). Methods A retrospective study was undertaken from January 2012 to September 2018 in 24 CSP patients in whom non-gonadal collaterals supplying GS were identified by arterial angiography performed immediately after UAE. These patients underwent attempt collateral embolization in addition to UA
View details →Negative / Null Result ReportOpen accessNursing
Nahid Mohammadi, Nasrin Soltani, Roya Amini et al. · 2018 · مراقبت پرستاری و مامایی ابن سینا
Introduction: Cardiovascular diseases are associated with individual behaviors in childhood, adolescence and youth. This article aimed to study the effect of education based on HBM on the prevention of heart disease in female students. Methods:This pre and post-test semi-experimental study which has two groups was conducted on 126 girls of high schools in 2017. A randomized cluster sampling method and relative randomize method were used in the first and second stages respectively. At first both groups completed a questionnaire and then instructions were given to intervention group in three ses
View details →Negative / Null Result ReportOpen accessPsychology
Miroslava Galasová, Matúš Grežo · 2021 · Studia Psychologica
The theory of action versus state orientation suggests that state-oriented people are more susceptible to sunk cost fallacy than action-oriented people because they ruminate about past costs and are reluctant to change their course of actions. However, research on the role of action versus state orientation in sunk cost fallacy is fairly limited. Therefore, the present paper aims to conceptually replicate the seminal study by van Putten et al. (2010) and verify whether action versus state orientation really matters in the susceptibility to sunk cost fallacy. We also examined the role of gender
View details →Negative / Null Result ReportOpen accessCytology
MĂźzeyyen Ozhavzali, UlkĂź Yazici, Funda Demirag et al. · 2010 · Folia Histochemica et Cytobiologica
This study investigated the immunohistochemical staining characteristics of glutathione-S-transferase alpha, pi, mu, theta and p53 in non-small cell lung carcinoma and normal lung tissue from 50 patients. The relationships between expressions of the Glutathione-S-transferase isoenzymes and some clinicopathological features were also examined. Expression of glutathione-S-transferase pi, mu, alpha, theta and p53 was assessed by immunohistochemistry for primary lung carcinomas of 50 patients from the Sanitarium Education and Research Hospital, Ankara lung cancer collection. The relationships betw
View details →Negative / Null Result ReportOpen accessEducation (General)
Zahra Karimian, Zahra Zolfaghari · 2024 · Frontiers in Education
E-students sometimes feel isolated due to the lack of face-to-face communication with teachers. It is important to pay attention to students’ learning styles and the virtual education methods used by teachers. This study aimed to investigate the preferences of students at Shiraz University of Medical Sciences (SUMS) regarding virtual education and their learning styles. A descriptive survey research was conducted on postgraduate e-students in 2019-2020. A stratified random sampling was performed among 300 students from four virtual master’s programs at SUMS. A total of 180 questionnaires were
View details →Negative / Null Result ReportOpen accessMedicine
Mohammad Reza Zarbakhsh Bahri, Zahra Shoa Hasani, Ziba Zahiri Sorori et al. · 2013 · پژوهان
Introduction: This study aims to evaluate the effectiveness of stress management training and problem-solving training on quality of life and life expectancy of infertile women was conducted.Material and Methods: The method of this study was experimental with pretest – posttest design with a control group. population of 400 infertile women who referred to infertility center in Rasht were randomized to 250 of them were selected and the quality of life and life expectancy of the study were the 45 members of the quality of life and life expectancy lower were more randomly in three groups of 15 pe
View details →Negative / Null Result ReportOpen accessMedicine
Hanzaleh Jour Ebrahimiyan, Nafise Ansarinejad, Farshid Fardad · 2023 · Disease and Diagnosis
Background: Chemotherapy-induced peripheral neuropathy is one of the most common side effects of chemotherapy. This study aimed to determine the effectiveness of venlafaxine and duloxetine in improving chronic neurotoxicity induced by chemotherapy in cancer patients. Materials and Methods: The study was performed on cancer patients undergoing outpatient chemotherapy or hospitalization in Rasoul Akram hospital. The admitted patients were blindly divided into two groups. The first group was treated with venlafaxine, and the second group was treated with duloxetine. The treatment lasted up until
View details →Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Hatem El Atroush, Hassan Effat, Mohamed Shehata et al. · 2012 · The Egyptian Heart Journal
Objective: To investigate the clinical significance of reciprocal ST segment depression on the presenting electrocardiogram in patients with acute inferior myocardial infarction. Design and setting: A prospective, randomized, controlled single center study done in the critical care department, Cairo university Hospital. Subjects: Forty consecutive patients with acute inferior myocardial infarction were enrolled in this study divided into two groups, 20 patients with reciprocal ST depression (group 1) and 20 patients without such depression (group 2). Interventions: All patients were investigat
View details →Negative / Null Result ReportOpen accessFood processing and manufacture
GUO Ziyu, HU Jiaqi, YANG Feifei et al. · 2024 · Shipin yu jixie
[Objective] This study aimed to investigate the effects of two pre-freezing methods (vacuum freezing and atmospheric pressure freezing) and two dipping methods (sucrose impregnation before pre-freezing and sucrose impregnation during freeze-drying) on the quality of freeze-dried apple slices. [Methods] The freeze-drying process was divided into six groups: vacuum pre-freezing without sucrose immersion (VFFD), atmospheric pre-freezing without sucrose immersion (CFFD), vacuum pre-freezing with sucrose immersion (BSVFFD), vacuum pre-freezing with sucrose immersion (MSVFFD), atmospheric pre-freezi
View details →Negative / Null Result ReportOpen accessComputer applications to medicine. Medical informatics
Chengyuan Hu, Zixin Lv, Jieping Zhu et al. · 2025 · Journal of Medical Internet Research
BackgroundLifestyle interventions are a critical component of weight loss programs, yet digital, personalized, and theory- and evidence-based lifestyle interventions remain limited. ObjectiveThis study aimed to investigate the effects of a combination of various dietary approaches and digital technology–based exercise on the body composition of college students with obesity. MethodsA total of 129 college students with obesity (mean age 18.3, SD 0.7 years; mean weight 89.9, SD 13.6 kg; mean BMI 30.6, SD 3.3 kg/m2) were initially recruited for this study. After excluding 2 participants, 127 stud
View details →Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Gan Gao, Fang‐bin Hao, Qian‐Nan Wang et al. · 2023 · Brain and Behavior
Abstract Introduction This study investigated the effect of indirect revascularization surgery in adult patients with moyamoya disease (MMD) complicated with hyperhomocysteinemia (HHcy), and the effect of HHcy on the progression of adult MMD. Methods A retrospective case‐control study was conducted in patients with MMD, with or without HHcy (n = 123). Postoperative collateral angiogenesis was evaluated using the Matsushima grading system and disease progression using the Suzuki staging system. Cerebral blood flow was evaluated before and after surgery using dynamic susceptibility contrast magn
View details →Negative / Null Result ReportOpen accessDiseases of the genitourinary system. Urology
Doo Sang Kim, Yoon Soo Kyung, Seung Hyo Woo et al. · 2011 · International Neurourology Journal
Purpose Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) exhibits variable lower urinary tract symptoms (LUTS). The aim of this study was to evaluate the incidence of LUTS and the efficacy of an anticholinergic agent in young and middle-aged CP/CPPS patients. Methods Ninety-six men with CP/CPPS were randomly assigned in a single-blind fashion and received either ciprofloxacin (group 1, 49 patients) or ciprofloxacin and solifenacin (5 mg/day; group 2, 47 patients) for 8 weeks. The National Institutes of Health chronic prostatitis symptom index (NIH-CPSI), the International Prostate Sy
View details →Negative / Null Result ReportOpen accessDiseases of the musculoskeletal system
Enas M Shahine, Tarek S Shafshak · 2014 · Egyptian Rheumatology and Rehabilitation
Objective The aim of this study was to compare the effects of bilateral arm training with auditory cueing (BATRAC) versus control intervention on motor performance of the upper extremity (UE) and to explore the central neurophysiological mechanism underlying this effect in moderately impaired chronic stroke patients. Design This was a randomized-controlled clinical trial. Materials and Methods Overall, 76 chronic stroke patients (mean age = 50.2 ± 6.2 years), 6-67 months after the onset of the first stroke were enrolled. They received either BATRAC (with both UE trained simultaneously in symme
View details →Negative / Null Result ReportOpen accessMedicine
Abu Sadat Mohammad Sayeem Bin Shahid, Shahnawaz Ahmed, Tanzina Tazul Renesa et al. · 2022 · PLoS ONE
Background Fibersol-2 has some beneficial effects on human health. We aimed to evaluate the digestive tolerability and acceptability of Fibersol-2 in healthy and diarrheal children, as well as improvement in stool consistencies in young diarrheal children. Methods Sixty children of either sex, aged 1-3 years having four groups (healthy children/low dose, healthy children/high dose, children with diarrhea/low dose and children with diarrhea/high dose) were enrolled into this exploratory study between 1st August to 23rd October 2017. Two presumptive doses, low (2.5g) and high (5g), twice daily w
View details →Negative / Null Result ReportOpen accessBiology (General)
Rosa Aghdam, Taban Baghfalaki, Pegah Khosravi et al. · 2017 · Genomics, Proteomics & Bioinformatics
Deciphering important genes and pathways from incomplete gene expression data could facilitate a better understanding of cancer. Different imputation methods can be applied to estimate the missing values. In our study, we evaluated various imputation methods for their performance in preserving significant genes and pathways. In the first step, 5% genes are considered in random for two types of ignorable and non-ignorable missingness mechanisms with various missing rates. Next, 10 well-known imputation methods were applied to the complete datasets. The significance analysis of microarrays (SAM)
View details →Negative / Null Result ReportOpen accessOrthopedic surgery
Jianzhong Kong, Yupeng Chu, Chengwei Zhou et al. · 2021 · Journal of Orthopaedic Surgery and Research
Abstract Background Anterior-posterior compression (APC) type II pelvis fracture is caused by the destruction of pelvic ligaments. This study aims to explore ligaments injury in APC type II pelvic injury. Method Fourteen human cadaveric pelvis samples with sacrospinous ligament (SPL), sacrotuberous ligament (SBL), anterior sacroiliac ligament (ASL), and partial bone retaining unilaterally were acquired for this study. They were randomly divided into hemipelvis restricted and unrestricted groups. We recorded the separation distance of the pubic symphysis and anterior sacroiliac joint, external
View details →Negative / Null Result ReportOpen accessVeterinary medicine
B. Mobini · 2013 · Veterinární Medicína
The present investigation aimed to evaluate the histomorphometric features of the skin of the Iranian native sheep (Bakhtiari breed). A total of 24 apparently healthy Iranian Bakhtiari sheep, aged 1-2 years were analysed and categorised on the basis of sex (12 females and 12 males). Samples were taken as small pieces from different regions of the skin, fixed and stained with H&E. The quantitative evaluations of different regions of skin were carried out using lattice line graticule (5 × 5) and light microscopy. The Student t-test and one-way ANOVA were used to analyse the data and detect signi
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