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19,847 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result Report

Very short-term monitoring of Romosozumab longitudinal effects in a cohort of postmenopausal women by means of Radiofrequency Echographic Multi-Spectrometry (REMS) technology

Semeraro A, Chialà A, Carafa A et al. · 2026 · Preprint

Abstract Background Romosozumab/AMG785 (Evenity®, Amgen and UCB pharma, RMZ) is a sclerostin-neutralizing antibody that rapidly increases BMD, but very short-term monitoring in clinical routine is limited by specific issues of available…

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Negative / Null Result ReportOpen accessMedicine

Postoperative Reduction in Postvoid Residual Urine Volume May Be Associated With Bladder Capacity Decrease Rather Than an Increase in Tidal Voided Urine Volume in Patients With Pelvic Organ Prolapse.

Kuroda K, Miyoshi H, Hamamoto K et al. · 2026 · The journal of obstetrics and gynaecology research

Aim More than half of patients with pelvic organ prolapse (POP) complain of lower urinary tract symptoms (LUTS), especially voiding difficulty. Surgical approaches such as laparoscopic sacrocolpopexy (LSC) and transvaginal mesh surgery…

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Negative / Null Result ReportMedicine

A wound dressing with copper and silver nanoparticles versus ionic silver hydrofibre dressing for the treatment of diabetic foot ulcers: a randomised clinical trial.

Roosimaa M, Ilumets H, Kaha T et al. · 2026 · Journal of wound care

Objective The objective of this trial was to compare the clinical performance and safety of a novel wound dressing containing silver and copper nanoparticles (Nanordica; Nanordica Medical OÜ, Estonia) (Ag/Cu) with the ionic silver-based…

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Negative / Null Result ReportMedicine

Loss of type III collagen has limited effect on tendon healing in young adult mice.

Tamburro MK, Carlson JA, Yen WK et al. · 2026 · Matrix biology : journal of the International Society for Matrix Biology

Tendon injuries account for considerable and escalating clinical burden. After injury, tendons heal poorly with persistent fibrovascular scar. Unlike healthy tendon which is type I collagen (COL1)-rich and highly-aligned, fibrovascular…

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Negative / Null Result ReportMedicine

Bacterial dysbiosis, cervicovaginal human papillomaviruses and inflammation persist in women living with HIV-1 after a year of antiretroviral treatment.

Lisco A, Borgognone A, Vanpouille C et al. · 2026 · The Journal of infectious diseases

Background The cervicovaginal microbiome may affect HIV-1 susceptibility and can in turn influence the prevalence and clinical course of HIV-1 and other sexually transmitted diseases. As the determinants, immunological correlates and…

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Negative / Null Result ReportMedicine

Low-frequency transient-evoked otoacoustic emission characteristics as potential indicators of hearing improvement in acute Ménière's disease: an exploratory analysis.

Yin TK, Sengar N, Fang TY et al. · 2026 · European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

PURPOSE: Fluctuating hearing loss in Ménière’s disease (MD) presents a key clinical challenge due to lack of reliable prognostic markers. The clinical value of transient-evoked otoacoustic emissions (TEOAEs) low-frequency components…

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Negative / Null Result ReportMedicine

Congestive heart failure in patients with acute respiratory distress syndrome: a secondary analysis of large randomized controlled trials.

Gkirgkiris K, Charalampaki E, Margioula E et al. · 2026 · Anaesthesia, critical care & pain medicine

Background stive heart failure may coexist and aggravate the non-cardiogenic pulmonary edema of acute respiratory distress syndrome (ARDS). Yet, patients with congestive heart failure are likely under-represented in ARDS trials. We aimed…

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Negative / Null Result ReportMedicine

Generating structure in soft solids: heat stable milk chocolate

Holian JA, Bolton MD, Wilson DI · 2025 · Current Research in Food Science

Addition of small amounts of glycerol to milk chocolate during the tempering stage can yield a product which exhibits enhanced mechanical strength and retards motion of the continuous phase (cocoa butter, a mixture of fats) of this dense…

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Negative / Null Result ReportMedicine

A Video Analysis Study Examining Neuromuscular Training Warm-Up Practices in Youth Soccer.

Lutz D, van den Berg C, Neill MG et al. · 2026 · Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine

Objectives To investigate time spent completing neuromuscular training (NMT) exercises in youth soccer team warm-up across a season considering sex, level of play, session type, and coach exposure and awareness of NMT. Design…

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Negative / Null Result ReportMedicine

Effect of Vitamin B12 Supplementation on Hematological and Athropometric Parameters in Children With Severe Acute Malnutrition, Aged 1 to 60 Months in Nutritional Rehabilitation Center (RCT).

Pathak BK, Maurya M, Mishra N et al. · 2026 · Clinical pediatrics

Microcytic hypochromic anemia is common in severe acute malnutrition (SAM) children, but macrocytic anemia (vitamin B12/folate deficiency) is not uncommon. Vitamin B12 deficiency leads to anemia and developmental slowing. We looked for the…

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Negative / Null Result ReportMedicine

Treatment in Public Centers for Adult Jewish Women Survivors of Childhood Sexual Abuse in Israel: Abuse Characteristics, Psychiatric Profiles, and One-Year Treatment Outcomes.

Lev-Ari L, Mintz Malchi K, Ludmir E et al. · 2026 · Journal of trauma & dissociation : the official journal of the International Society for the Study of Dissociation (ISSD)

Background Childhood sexual abuse (CSA) is associated with significant psychiatric morbidity and has been reported at notable rates among Jewish Israeli women. Yet data regarding abuse characteristics, psychiatric history and longitudinal…

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Negative / Null Result ReportMedicine

Mavacamten Versus Alcohol Septal Ablation in Obstructive Hypertrophic Cardiomyopathy: An Echocardiography-Derived Pressure-Volume Analysis.

Reil JC, Sequeira V, Coppée C et al. · 2026 · Circulation. Heart failure

Background Obstructive hypertrophic cardiomyopathy (oHCM) is characterized by left ventricular (LV) outflow tract obstruction, which increases afterload and chronically activates the Anrep response, a compensatory (afterload-driven) state…

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Negative / Null Result ReportOpen accessMedicine

Brief intervention for inappropriate z-hypnotics use in older adults: a before and after intervention study in primary care.

Siddiqui TG, Simonsen THB, Lie Selle M et al. · 2026 · Scandinavian journal of primary health care

Background Z-hypnotics are commonly prescribed for insomnia, but their use in older adults is associated with an increased risk of adverse events. Aim We examined the long-term effect of brief intervention (BI) for inappropriate z-hypnotic…

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Negative / Null Result ReportMedicine

Introduction of a dashboard visualizing outcome information during healthcare visits in Chronic Kidney Disease - An evaluation study.

van der Horst DEM, van Uden-Kraan CF, Stiggelbout AM et al. · 2026 · Patient education and counseling

Objective Effective patient-clinician communication is essential in chronic kidney disease (CKD) to support treatment adherence and slow down disease progression. In this proof-of-concept study we evaluated the effects of a CKD dashboard,…

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Negative / Null Result ReportMedicine

Repeated Melatonin Implant Improves Testicular Volume, Testicular Blood Flow, Estradiol, Antioxidant Capacity, and Nitric Oxide Levels in Post-Pubertal Camels Under Heat Stress Conditions.

Abdelnaby EA, Alhaider AK, Emam IA · 2026 · Reproduction in domestic animals = Zuchthygiene

This current work aimed to determine the impacts of melatonin implants on testicular artery blood flow and Doppler indices, in relation to hormonal profile in post-pubertal camels (Camelus dromedaries) under heat stress and non-breeding…

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Negative / Null Result ReportMedicine

Effect of Vericiguat on Pulmonary Artery Pressures in Patients With Heart Failure: Real-World Insights From Pressure Sensor Monitoring.

Elad B, Lotan D, Richter I et al. · 2026 · Journal of cardiovascular pharmacology

Abstract Vericiguat improves outcomes in heart failure (HF) by promoting vasodilation of the systemic and pulmonary arterial beds. Little is known about its impact on pulmonary artery pressure (PAP). We aimed to study this effect using…

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Negative / Null Result ReportOpen accessMedicine

Effect of an Eight-Week Breathing Exercise Program on the Respiratory Function and Craniovertebral Angle in Dental Students: A Pre-test and Post-test Quasi-experimental Study.

Hafez E, Ashraf E, Saeed S et al. · 2026 · Cureus

Introduction Dental training requires prolonged static and forward-leaning working positions that may contribute to forward head posture. Forward head posture can be quantified using the craniovertebral angle (CVA) and may be associated…

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