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Browse the failure-mode index

20,227 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

What Is the Impact of Second Language Exposure and Intellectual Disability Status on Executive Function and Functional Communication Outcomes in Children and Adolescents With and Without Autism Spectrum Disorder (ASD)?

Hutchison SM, DiazPinzon N, Oberlander TF et al. · 2025 · Autism research : official journal of the International Society for Autism Research

Over the past 10 years, research has suggested no negative effect on second language exposure in children with autism spectrum disorder (ASD), yet, parents and professionals may be concerned that using a second language with a child with…

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Negative / Null Result ReportOpen accessMedicine

Immune Globulin

· 2006

Immune globulin G (IgG) is a normal component of breastmilk. Data from 2 mothers indicate that IgG concentrations in milk are normal or higher and IgM levels in milk are normal or lower during intravenous immunoglobulin (IVIG) therapy. The…

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Negative / Null Result ReportMedicine

Caregiver emotional support and youth mental health after sexual abuse.

Sitton MJ, McDonald R, Rosenfield D et al. · 2026 · Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43)

Emotional support from a caregiver is theorized to benefit adolescents after sexual abuse, yet the empirical evidence for this is inconsistent. The present study examines the cross-sectional relation between caregiver emotional support and…

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Negative / Null Result ReportMedicine

Mobile App Use in Clinical Care for Cleft Patients in the UK and Republic of Ireland.

de Berker HT, Rivers CM · 2026 · The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

ObjectiveTo establish whether mobile applications (apps) are used as part of routine care for patients with cleft lip and palate in the UK and Republic of Ireland and to determine what role apps could play in the delivery of care.DesignA…

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Negative / Null Result ReportMedicine

Tumor-induced rickets/osteomalacia (TIO): diagnostic pitfalls and therapeutic options.

Ito N, Fukumoto S · 2025 · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

A 10-year-old girl developed bilateral gonalgia and waddling gait. Biochemical and imaging studies showed hypophosphatemia with impaired proximal tubular phosphate reabsorption and high intact fibroblast growth factor 23 (FGF23) level,…

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Negative / Null Result ReportOpen accessMedicine

Randomized controlled trial of intravenous dexamethasone to prevent relapse in the treatment of migraine in a pediatric emergency department.

Tourigny-Ruel G, Bailey B, Jean-Charles S et al. · 2026 · Headache

Objective This study aimed to evaluate whether a single dose of intravenous dexamethasone, when added to standard abortive therapy, reduces relapse of migraine after emergency department (ED) discharge in children and adolescents.…

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Negative / Null Result ReportMedicine

The European earwig Forficula auricularia (Dermaptera: Forficulidae) in California citrus: a sampling method, population surveys, and description of earwig movement into the tree canopy.

Rosenheim JA, Cluff E, Morrow K · 2025 · Journal of economic entomology

The European earwig F. auricularia L. is an omnivore that has only recently been identified as a direct, fruit-feeding pest of citrus. Here, we start to build the basic tools needed for integrated pest management for this species. We…

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Negative / Null Result ReportOpen accessMedicine

Looking for Biomarkers Which May Explain Idiopathic Environmental Intolerance Attributed to Electromagnetic Fields (IEI-EMF): Does RF-EMF Exposure Influence Salivary Cortisol Response?

Verrender A, Manley J, Wallace NK et al. · 2025 · Bioelectromagnetics

In order to understand Idiopathic Environmental Intolerance attributed to Electromagnetic Fields (IEI-EMF), it has been argued that it is crucial to test for effects of radiofrequency electromagnetic fields (RF-EMF) on biomarkers, given…

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Negative / Null Result ReportOpen accessMedicine

Repeated Tetrahydrocannabinol Injections Induce Tolerance but Do Not Disrupt Ongoing Behaviour Upon Withdrawal in Male and Female Rats With Inflammatory Pain.

Morgan MM, Hickey CM · 2026 · European journal of pain (London, England)

Background Many people use cannabis to self-medicate for pain. Little is known about the impact of pain on tolerance and spontaneous withdrawal to delta-9-tetrahydrocannabinal (THC), the primary psychoactive compound in cannabis. Our…

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Negative / Null Result ReportMedicine

Variation in Maternal Effort, Activity Budgets, and Feeding Behavior in Wild Saddleback Tamarins (Leontocebus weddelli) in Northwestern Bolivia.

Erb WM, Porter LM, Voyt R et al. · 2025 · American journal of primatology

Among primates, maternal infant care may vary in response to several factors including litter size, reproductive history, and health status. In cooperative breeders, maternal investment may also depend on the amount of help their group…

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Negative / Null Result ReportMedicine

Transition from classic to expanded Denver screening criteria for blunt cerebrovascular injury: lessons from a high-volume level I trauma center.

Casado-Ruiz J, Castaño-Leon AM, García-Escudero L et al. · 2025 · Journal of neurosurgery

Objective Blunt cerebrovascular injuries (BCVIs) are associated with significant morbidity and mortality. To identify patients with BCVI who were undetected using the classic criteria, researchers designed the expanded Denver screening…

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Negative / Null Result ReportMedicine

Childhood poverty and its impact on financial decision making under threat: A preregistered replication of Griskevicius et al. (2011b).

Gladstone JJ, Lehman M, Decker M · 2025 · Journal of experimental psychology. Applied

We investigated the influence of childhood poverty on financial decision making under threat by replicating the findings of Griskevicius et al. (2011b), which found that individuals from lower socioeconomic backgrounds tend to make riskier…

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Negative / Null Result ReportOpen accessMedicine

A Comparison of Vessel Density in Primary Open-Angle Glaucoma and Normal-Tension Glaucoma Patients Using OCT Angiography.

Zehavi-Dorin T, Kutzscher AE, Badr M et al. · 2026 · Clinical ophthalmology (Auckland, N.Z.)

Purpose To compare global peripapillary and perifoveal vessel densities between primary open-angle glaucoma (POAG) and normal-tension glaucoma (NTG) patients with the same glaucoma severity using optical coherence tomography angiography…

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Negative / Null Result ReportOpen accessMedicine

Cognitive Therapy vs. Short-Term Dynamic Psychotherapy in a Community Mental Health Setting: A Preliminary Analysis of Effects in Several Severity Domains.

Gibbons MBC, Kodkany N, Liow Y et al. · 2026 · Clinical psychology & psychotherapy

Objective To investigate the effectiveness of cognitive therapy (CT) and short-term dynamic psychotherapy (STDP) among patients with greater severity, defined in several ways, in a community mental health setting. Method Using data from a…

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Negative / Null Result ReportMedicine

White matter integrity and verbal memory following a first episode of psychosis: A longitudinal study.

Ghanem J, Totzek JF, Henri-Bellemare C et al. · 2025 · Progress in neuro-psychopharmacology & biological psychiatry

Psychotic disorders are heterogeneous disorders for which there is evidence of structural and functional brain abnormalities. The role of white matter integrity, often measured via Fractional Anisotropy (FA), has played a controversial…

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