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19,847 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Metabolically healthy obesity and risks of cardiovascular disease and all-cause mortality, a matched cohort study: the Shizuoka study.

Tabara Y, Shoji-Asahina A, Ogawa A et al. · 2024 · International journal of obesity (2005)

Background Metabolically healthy obesity is not always a benign condition. It is associated with an increased incidence of cardiovascular disease and all-cause mortality. We investigated the prognostic significance of metabolically healthy…

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Negative / Null Result ReportOpen accessMedicine

Association of Hormone Replacement Therapy with Inflammatory Bowel Disease Risk in Women with Menopausal Disorders: A Population-Based Retrospective Cohort Study.

Tseng YT, Chen II, Wang CH · 2025 · Healthcare (Basel, Switzerland)

Background : The long-term effects of hormone replacement therapy (HRT) on inflammatory bowel disease (IBD) remain unclear, necessitating further investigations of the association between HRT and the development of ulcerative colitis and…

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Negative / Null Result ReportMedicine

Association between pregnancy intention and postpartum contraceptive interest among pregnant people with opioid use disorder.

Schiff DM, Wheeler A, Lewis D et al. · 2026 · Journal of substance use and addiction treatment

Objective Identify sociodemographic and substance use characteristics associated with pregnancy intention and explore the relationship between pregnancy intent and postpartum contraception interest among pregnant individuals with opioid…

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Negative / Null Result ReportOpen accessMedicine

Long-Term Impact of Orthodontic Treatment on Oral Behaviours, Temporomandibular Disorder-Related Pain, and Anxiety: An 18-Month Prospective Study.

Reda B, Zanon G, Contardo L et al. · 2025 · Orthodontics & craniofacial research

Objective Orthodontic treatment is a common approach for correcting malocclusion but is often associated with discomfort. The aim of this study was to assess the longitudinal changes in oral behaviours, temporomandibular disorder…

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Negative / Null Result ReportOpen accessMedicine

Assessment of Eating Behavior and Genetic Risk Factors for Metabolic Syndrome.

Turmanbayeva A, Sadykova K, Nuskabayeva G et al. · 2026 · Journal of clinical medicine

Background : Metabolic syndrome (MetS) is influenced by behavioral and genetic factors, yet evidence on eating behavior patterns and related genetic polymorphisms in Central Asian populations remains limited. Aim: The aim of this study was…

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Negative / Null Result ReportOpen accessMedicine

Visual processing and interference performance influences on knee angular impulse in ACLR individuals: a cognitive-biomechanical analysis of drop-jumps.

Santamaria-Guzman K, Holmes H, Kosek J et al. · 2026 · Archives of orthopaedic and trauma surgery

Introduction Visual processing speed and cognitive interference control are critical for athletic performance and Anterior Cruciate Ligament (ACL) injury risk. However, how these cognitive functions relate to biomechanical performance…

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Negative / Null Result ReportOpen accessMedicine

A high-risk perioperative atrial fibrillation phenotype and early outcomes after isolated coronary artery bypass grafting.

Khalil E, Yüksel B · 2026 · Archives of medical sciences. Atherosclerotic diseases

Introduction Perioperative atrial fibrillation (POAF) remains the most common arrhythmic complication occurring in the setting of isolated coronary artery bypass grafting (CABG), and it is now being increasingly recognised as a marker of…

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Negative / Null Result ReportOpen accessMedicine

Association between Levels of Alcohol Use, Perceived HIV Risk, and Untreated HIV Among Persons at Alcohol-Serving Venues in Kenya and Uganda.

Beesiga B, Litunya J, Nakato JZ et al. · 2026 · AIDS and behavior

Alcohol-serving venues in East Africa are high-risk environments for HIV transmission but few studies in sub-Saharan Africa (SSA) have examined perceived HIV risk and sexual risk behaviors by alcohol use levels on a broader population of…

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Negative / Null Result ReportOpen accessMedicine

Effectiveness of Emotion-Focused Cognitive Behaviour Therapy on Emotional Hyporexia Among Adolescent Girls with Eating Problems: A Pilot Study.

Shinde SS, Naik NS, Adhyapak SU et al. · 2025 · Journal of pharmacy & bioallied sciences

Background Emotional hyporexia, a form of intentional food avoidance triggered by emotional distress, presents a growing health concern among adolescent girls. Addressing this behavior through psychological intervention is essential for…

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Negative / Null Result ReportOpen accessMedicine

A Longitudinal Observational Study on Lactation-Associated Changes in Procalcitonin, Protein Carbonyl Content, Asymmetric Dimethylarginine, and Symmetric Dimethylarginine in Dairy Cattle.

Sala G, Castelli M, Orsetti C et al. · 2025 · Veterinary sciences

Procalcitonin (PCT), protein carbonyl content (PCC), asymmetric dimethylarginine (ADMA), and symmetric dimethylarginine (SDMA) have been proposed as promising biomarkers for detecting diseases in cattle. Their concentrations could…

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Negative / Null Result ReportOpen accessMedicine

Influence of Coagulation Factor VIII on Ischemic Stroke.

Martínez-Salmerón MDM, Amaya-Pascasio L, Martínez-Sánchez P et al. · 2026 · Revista de neurologia

Background There is considerable interest in the underlying mechanisms of cryptogenic stroke, with hypercoagulable states being widely studied. An elevated level of Factor VIII has been proposed as a potential prothrombotic marker…

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Negative / Null Result ReportOpen accessMedicine

Influence of Catechol-O-Methyltransferase (COMT) Val158Met Polymorphism in Conditioned Pain Modulation in Women with Migraine.

Cigarán-Méndez M, de-la-Llave-Rincón AI, Pacho-Hernández JC et al. · 2026 · International journal of molecular sciences

The role of the catechol-O-methyltransferase (COMT) Val158Met rs4680 polymorphism in altered pain processing in headaches is controversial. The aim of this study was to investigate the influence of the Val158Met rs4680 polymorphism in…

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Negative / Null Result ReportMedicine

Impact of metabolism-related markers on outcomes in ovarian cancer patients: Findings of the MITO16A/MaNGO-OV2 trial.

Indraccolo S, Signoriello S, Piga I et al. · 2024 · The International journal of biological markers

Introduction In ovarian cancer, expression of metabolism-related markers has been investigated in several studies focusing on individual markers; however, a parallel quantitative evaluation of markers mapping to distinct metabolic…

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Negative / Null Result ReportOpen accessMedicine

Performance of Early Therapeutic Paracentesis in Spontaneous Bacterial Peritonitis and Its Effect on Clinical Outcomes.

Wentworth BJ, Shwetar M, Mallawaarachchi I et al. · 2026 · JGH open : an open access journal of gastroenterology and hepatology

Background and aims Spontaneous bacterial peritonitis (SBP) is common in decompensated cirrhosis and often accompanied by large volume ascites. However, the safety of early therapeutic paracentesis is unknown and may lead to unnecessary…

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Negative / Null Result ReportMedicine

Assessment of the impact of microplastic ingestion in striped red mullets from an Eastern Mediterranean coastal area (Zakynthos Island, Ionian Sea).

Patsiou D, Digka N, Galli M et al. · 2024 · Marine environmental research

Monitoring microplastics (MPs) in the marine environment is an ongoing process, and our understanding of their impact on marine organisms is limited. The present study evaluates the effects of ingested MPs on the marine MP pollution…

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Negative / Null Result ReportOpen accessMedicine

Stable bloodstream infection rates despite rising colonization: insights from a hospital system using in-house polymerase chain reaction screening for <i>Candidozyma auris</i>.

Rosa R, Rosello G, Manzanillo K et al. · 2025 · Antimicrobial stewardship & healthcare epidemiology : ASHE

Following the implementation of in-house Candidozyma auris ( C. auris ) polymerase chain reaction as part of our surveillance strategy, we observed increasing incidence rates of colonization with C. auris already present at hospital…

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Negative / Null Result ReportOpen accessMedicine

Ki67 and Lymphovascular Invasion as Histopathological Predictors of Residual Cancer Burden After Neoadjuvant Chemotherapy in Breast Cancer: A Retrospective Study.

Carabas BA, Țǎpoi DA, Costache M · 2026 · Diagnostics (Basel, Switzerland)

Background: Neoadjuvant chemotherapy (NAC) is widely used in the management of stage I-III breast cancer, with tumor regression serving as an important surrogate for long-term outcome. Identifying reliable pathological biomarkers…

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Negative / Null Result ReportOpen accessMedicine

Helicobacter pylori in the Philippines: Social and Ecological Determinants of Seropositivity and Lack of Association With Systemic Inflammation.

Lee CC, Miller AA, Tallman PS et al. · 2025 · American journal of human biology : the official journal of the Human Biology Council

Helicobacter pylori (H. pylori) is a bacterium that infects the stomach and is associated with various gastrointestinal outcomes and increased cardiovascular disease risk. We examined the role of sex in and the social and ecological…

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Negative / Null Result ReportOpen accessMedicine

Circulating Levels of Soluble α-Klotho and FGF23 in Childhood Cancer Survivors: Lack of Association with Nephro- and Cardiotoxicity-A Preliminary Study.

Kozłowski K, Konończuk K, Muszyńska-Rosłan K et al. · 2024 · Journal of clinical medicine

Background/Objectives: The survival rate among pediatric cancer patients has reached 80%; however, these childhood cancer survivors (CCSs) are at a heightened risk of developing chronic conditions in adulthood, particularly kidney and…

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