20,217 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Fatima H, Schaffert J, Carlew AR et al. · 2025 · The Clinical neuropsychologist
Objective Cognitive dispersion (CD) or neuropsychological test score variability has been associated with more rapid cognitive decline, and the development of mild cognitive impairment (MCI) and Alzheimer's disease (AD). The predictive…
View details →Agyeman AA, Buggiotti L, Brown LK et al. · 2026 · British journal of clinical pharmacology
Aims The repurposed use of favipiravir in COVID-19 has been reported to have limited clinical efficacy, yet it has been widely used in some countries. Favipiravir causes mutagenesis in RNA viruses, and it is currently unknown whether it…
View details →Khoshnevis A, Zayernouri M, Malete L et al. · 2026 · Journal of voice : official journal of the Voice Foundation
Objective Voice-based biomarkers have been proposed as objective tools for anxiety assessment, yet existing research relies on small, demographically homogeneous samples and shows inconsistent associations between fundamental frequency (F…
View details →Kwon Y, Park J, Kim D et al. · 2026 · Obesity surgery
Background While bariatric surgery (BS) is an effective treatment for gout in patients with morbid obesity, little is known about how BS influences subsequent use of gout medications. We investigated the impact of BS on gout medication…
View details →Golparian A, Anbarian M, Golparian M · 2026 · Journal of biomechanics
Anterior cruciate ligament deficiency (ACLD) leads to knee instability and altered gait patterns. Individuals with ACLD can be classified as copers or noncopers. Lower-limb coordination and coordination variability may reflect compensatory…
View details →Sınır B, Ortan P, Sayin SS et al. · 2026 · Respiratory medicine
Purpose Obstructive sleep apnea syndrome (OSAS) causes intermittent hypoxia and sleep fragmentation, which may alter gut microbiota composition. We primarily aimed to compare intestinal Desulfovibrio detection/abundance between patients…
View details →Kumar A, Sinha RRK, Sahu SP et al. · 2026 · Preprint
Abstract The present experiment was conducted to compare three housing systems Individual cages, Colony cages and Deep litter on welfare, behaviour, and physiological traits in Rhode Island Red laying hens under tropical conditions. A…
View details →Okumura M, Yamagami S, Akiyama M et al. · 2026 · Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing
Introduction Pulsed field ablation (PFA) is a non-thermal ablation modality, but repeated high-voltage applications can still cause Joule heating at the electrode-tissue interface. We evaluated the effects of application repetition and…
View details →Xiang F, Lin J, Chen B et al. · 2026 · The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
Background To compare the superthin (3-5 mm) versus conventional (≥10 mm) anterolateral thigh (ALT) flap for post-traumatic ankle reconstruction. Methods Retrospective cohort (2020-2024): superthin ALT (n=26) vs conventional ALT (n=34).…
View details →Jeong Y, Park KH, Jeoung JW · 2026 · The British journal of ophthalmology
Background/aims This study evaluates the relationship between the iridotrabecular contact (ITC) index and various anterior segment parameters, with a particular focus on lens-related parameters, given their clinical relevance in primary…
View details →Kang Y, Workneh F, Yibeltal K et al. · 2026 · The Journal of nutrition
Background Suboptimal gestational weight gain (GWG) is associated with adverse pregnancy outcomes; however, evidence on the impact of nutritional interventions on GWG in low-income settings remains limited. Objectives This study aims to…
View details →Allotey J, Junaid F, Peréz T et al. · 2026 · BMJ neurology open
Background Serum lamotrigine concentrations fall during pregnancy, and therapeutic drug monitoring is often used to guide dose adjustment. We do not know whether serial antenatal measurements improve prediction of seizure risk in pregnant…
View details →Orozco MPV, Seefluth D, Ciston AB et al. · 2025 · Preprint
Focusing on external movement outcomes rather than the movements themselves has been reported to enhance motor performance, although the mechanisms for this attentional focus effect remain unclear. We examined whether the effectiveness of…
View details →Nyström L, Granhag A, Neofotistos E et al. · 2026 · Preprint
Introduction. The Shift-of-Strategy (SoS) approach aims to obtain concealed information from semi-cooperative suspects by prompting them to shift toward more forthcoming counter-interrogation strategies. While previous studies on the…
View details →Khan A, Islam I, Mannakkara N et al. · 2026 · Future cardiology
Background Echocardiography after myocardial infarction (MI) provides clinically useful information through assessment of regional wall motion abnormalities, but interpretation requires expertise and remains subject to observer…
View details →Ystrøm IK, Jensen SK, Andersen IT et al. · 2026 · Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Background and hypothesis IgA nephropathy (IgAN) is the leading cause of primary glomerulonephritis; however, reported incidences and prevalences vary substantially across countries. This study assessed the epidemiology of IgAN including…
View details →van de Bovenkamp AA, Nassiri S, de Man FS et al. · 2026 · European journal of heart failure
Aims Iron deficiency (ID) is common in patients with heart failure with preserved ejection fraction (HFpEF). The IRON-HFpEF trial aimed to evaluate the mechanistic effects of intravenous iron supplementation on cardiovascular function and…
View details →Yi Y, Yano K · 2025 · Physiologia Plantarum.
Elevated CO₂ (eCO₂) can enhance plant growth, but it may also accelerate senescence, which could offset the growth benefits. Phosphorus (P) supply can enhance the photosynthetic rate under eCO₂ conditions and promote biomass accumulation.…
View details →Steuber T, Graetz C, Springer C et al. · 2026 · International journal of dental hygiene
Objective This two-centre, double-blind, randomized, parallel-group study compared the efficacy and safety of a novel powered full-mouth cleaning device system (FMCD) with habitual toothbrushing (CG) in patients with generalized gingivitis…
View details →Okazaki T, Imagama T, Matsuki Y et al. · 2026 · The Journal of arthroplasty
Background The use of highly-porous acetabular components in total hip arthroplasty (THA) has gained popularity. To elucidate the clinical and radiological outcomes of three-dimensional (3D)-printing highly porous cups, we compared…
View details →Zullo F, Chen H, Hoffman MK et al. · 2026 · Preprint
Objective: To ascertain if the adverse outcomes differ significantly in individuals without versus with one prior cesarean delivery(CD). Design: Population-based, retrospective cohort. Setting: U.S. Vital-Statistics birth-infant…
View details →Patel AA, Levi JR, Weber PC · 2026 · The Annals of otology, rhinology, and laryngology
Objective While prior literature has demonstrated that patients of lower socioeconomic groups may have larger tumors on presentation and poorer outcomes, there is limited literature on the impact of race and ethnicity on management of…
View details →Heinrich C, Hofstaetter H, Puschkasch-Möck S et al. · 2026 · European journal of applied physiology
Objective To evaluate conventional hamstring-to-quadriceps ratio across the menstrual cycle in distinct angular velocities in an eumenorrheic, physically active population. Design Repeated measures within-subjects design. Methods…
View details →Avsar FN, Erinc O, Sahutoglu T · 2026 · Hemodialysis international. International Symposium on Home Hemodialysis
Introduction Depression is prevalent in maintenance hemodialysis patients and is influenced by the interplay of physical and mental health. Rather than a direct antidepressant effect of dialyzer membrane type, improved clearance of middle…
View details →Pontecorvo AA, Cornejo J, Tsenteradze T et al. · 2026 · Journal of robotic surgery
This study aimed to evaluate and compare perioperative outcomes of robotic versus laparoscopic cholecystectomy in patients with acute cholecystitis within an Acute Care Surgery setting. A retrospective cohort study was conducted including…
View details →Iurchenkov A, Danilova A, Shilo P et al. · 2026 · Cancers
Background : Immune checkpoint inhibitors have significantly improved survival in metastatic melanoma. Combination nivolumab plus ipilimumab demonstrated superior efficacy in randomized trials, including CheckMate 067, but data beyond the…
View details →harada k, ikeda s, makino j · 2026 · Preprint
Abstract Background Prolonged intensive care unit (ICU) stays are associated with increased mortality and functional decline. Time-limited trials (TLTs) support decision-making under prognostic uncertainty; however, uncertainty may persist…
View details →Guan X, Li X, Yue M et al. · 2026 · Scientific reports
Pressure injury (PI) prevention requires sustained nursing behaviors from patients, caregivers, and nurses. This single-center quasi-experimental, non-randomized, non-equivalent control group study enrolled 60 inpatients with PI or high PI…
View details →Çarikçi F, Girgin BA, Harmanci NF et al. · 2026 · Child abuse & neglect
Aim To examine and compare the proficiency of pediatric physicians and nurses in recognizing the signs of and risk factors for child maltreatment, as well as to determine the relationship between this proficiency and their reporting…
View details →Inokuchi T, Hiraoka S, Oshima N et al. · 2026 · Gerontology
Introduction We previously reported the findings of a multicenter retrospective cohort study investigating the efficacy of oral tacrolimus induction therapy in patients with ulcerative colitis (UC). In this subanalysis, we specifically…
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