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Browse the failure-mode index

19,843 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Longitudinal Changes in Health Utility Scores During the Perioperative Period Among Patients With Oral Cancer: An Analysis of the Effect of Older Age and Social Background.

Sasaki M, Aoki T, Uchibori M et al. · 2026 · Oral diseases

Objective Many countries have implemented health technology assessment of their public medical insurance programs owing to rising social security costs from ageing populations and expensive emerging medical technologies. Clarifying factors…

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Negative / Null Result ReportOpen accessMedicine

Effects of insect-derived protein form and replacement level on growth performance and skeletal traits in broiler pheasants (Phasianus colchicus).

Osiak-Wicha C, Kras K, Tomaszewska E et al. · 2026 · Poultry science

This study evaluated black soldier fly (Hermetia illucens) products as alternatives to soybean meal protein in broiler pheasants, focusing on growth performance and skeletal traits in both sexes. Birds were assigned to five dietary…

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Negative / Null Result ReportMedicine

Comparison of Dexmedetomidine Administration Strategy for Propofol-Based Pediatric Sedation for Magnetic Resonance Imaging: A Retrospective Study.

Kim TW, Ji SH, Park JB et al. · 2026 · Paediatric anaesthesia

Background Intravenous dexmedetomidine is a safe and effective adjunct in propofol-based sedation. Dexmedetomidine is typically administered as a loading dose, followed by continuous infusion or not. Whether the addition of a maintenance…

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Negative / Null Result ReportMedicine

Immune-impulsivity link: association between peripheral inflammatory ratios and borderline personality disorder.

Raj R, Nabi J, Gidwani S et al. · 2026 · East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan

Objectives To determine associations between impulsivity and peripheral inflammatory ratios in patients with borderline personality disorder (BPD). Methods Consecutive patients aged ≥18 years with a diagnosis of BPD who presented to the…

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Negative / Null Result ReportOpen accessMedicine

Comparative Effectiveness of Azithromycin versus Erythromycin for Latency Prolongation in Preterm Prelabor Rupture of Membranes < 34 Weeks of Gestation.

Chawanpaiboon S, Pooliam J · 2026 · International journal of women's health

Objective Preterm prelabor rupture of membranes (PPROM) is a major contributor to preterm birth and neonatal morbidity. Although azithromycin is increasingly used as an alternative to erythromycin for latency antibiotic therapy,…

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Negative / Null Result ReportMedicine

Comparative evaluation of root dentin thickness following hand and rotary instrumentation of primary molar root canals using cone-beam computed tomography - an invitro study.

Thomas RM, Nayak R, Madi M et al. · 2026 · BMC oral health

Remaining Root Dentin Thickness (RRDT) after root canal instrumentation is an important parameter to be assessed with newer file systems. This study aimed to evaluate the root dentin thickness following instrumentation of primary molar…

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Negative / Null Result ReportMedicine

Comparative study of prosthesis implantation, latissimus dorsi flap, and combined reconstruction immediately after breast cancer surgery: A retrospective, single-center, observational cohort study.

Zhang Y, Yu W, Shen W · 2026 · Medicine

This study aimed to explore the effects of 3 immediate reconstruction methods - prosthesis implantation, latissimus dorsi flap (LDF), or their combination - on postoperative outcomes following breast cancer (BC) surgery. A retrospective,…

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Negative / Null Result Report

Immersive Virtual Reality in Undergraduate Critical Care Nursing Education: A Pragmatic Three-Cohort Quasi-Experimental Evaluation of Perceived Simulation Effectiveness and Clinical Learning Needs

Ismaile S, Alhosban F, Shajrawi A et al. · 2026 · Preprint

Abstract Background Preparing undergraduate nurses for high-acuity practice requires educational approaches that allow safe rehearsal of complex clinical situations, yet evidence from routine programme delivery remains mixed when immersive…

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Negative / Null Result ReportMedicine

Effect of Remimazolam or Propofol Combined With Esketamine on Anesthesia and Early Perioperative Neurocognitive Disorders in Patients Undergoing Thoracoscopic Partial Lung Resection: A Randomized Clinical Trial.

Yuan W, Liang X, Zhang R et al. · 2026 · Clinical therapeutics

Purpose This study aimed to evaluate the effects of remimazolam in conjunction with esketamine on anesthesia and the incidence of early perioperative neurocognitive disorders (PNDs) in patients undergoing thoracoscopic partial lung…

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Negative / Null Result Report

Safety and short-term outcomes during the introduction of retroperitoneal single-port robot-assisted radical prostatectomy: a single-surgeon comparison with transperitoneal multiport radical prostatectomy in a Japanese population

Hattori S, Shimizu K, Kotorii R et al. · 2026 · Preprint

Abstract Purpose. To evaluate the safety and feasibility of introducing retroperitoneal single-port robot-assisted radical prostatectomy (SP-RARP) by comparing a single surgeon’s initial 50 cases with 50 recent transperitoneal multiport…

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Negative / Null Result ReportMedicine

Challenge Under Pressure Contextual Interference or Differential Learning.

Taghizadeh H, Parvizi MJ, Roostaei A et al. · 2026 · Research quarterly for exercise and sport

This study compared the effects of blocked practice, random practice (contextual interference), and differential learning on acquisition, retention, and performance under psychological pressure of a basketball jump shot in novice…

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Negative / Null Result Report

Evaluating the sensitivity of heart rate variability fractal correlation properties to training load variations: Implications for monitoring training readiness and durability

van Rassel CR, Rummel M, MacInnis MJ · 2026 · Preprint

This study examined the utility of HRV detrended fluctuation analysis alpha-1 (DFAα1) to assess readiness-to-train and exercise durability under varying acute training loads. Nineteen trained cyclists completed two 20-minute time-trials…

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Negative / Null Result ReportMedicine

Evaluation of Osteomeatal Complex Anatomical Variations, Pathologies and Nasal Cavity Volume in Patients with Cleft Lip and Palate.

Cebeci T, Polat Akmansoy B · 2026 · The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

ObjectiveTo compare osteomeatal complex (OMC) anatomical variations and nasal cavity airway volume between individuals with cleft lip and palate (CLP) and healthy controls using cone beam computed tomography (CBCT).DesignRetrospective,…

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Negative / Null Result ReportMedicine

The use of partially slatted floor designs as an alternative to littered systems in broiler chickens. II. The effects on welfare and behavioral traits.

Çavdarcı H, Sarıca M, Erensoy K et al. · 2026 · Tropical animal health and production

This study investigated the effects of different flooring designs on the welfare and behavioral traits in fast-growing broilers. A total of 600 day-old Ross-308 chickens were randomly allocated to five treatment groups: fully littered…

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Negative / Null Result ReportMedicine

Sublethal effects and bioaccumulation of "smart" anti-corrosion nanoadditives spiked in sediment in the ragworm Hediste diversicolor.

Bruni M, Perina F, Figueiredo J et al. · 2026 · Aquatic toxicology (Amsterdam, Netherlands)

Metallic corrosion poses an economic problem worldwide and is often mitigated by adding corrosion inhibitors (CIs) to protective coatings. Conventional CIs, such as 2-mercaptobenzothiazole (MBT) and benzotriazole (BTA), exhibit toxicity to…

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