19,843 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Wang F, Chen L, Xu X et al. · 2026 · Preprint
Abstract Background This study aimed to apply a 3D vertical cephalometric analysis to evaluate vertical skeletal relationships in adult patients. Methods The CBCT data of ninety-seven first-visit adult patients were retrospectively…
View details →Khalid H, Tsai WS, Lamanna F et al. · 2026 · The British journal of ophthalmology
Background/aims To characterise the distribution of retinal non-perfusion and its relationship with neovascularisation elsewhere (NVE) and visual acuity (VA) in referable diabetic retinopathy (DR) using ultra-widefield fluorescein…
View details →Sun C, Zhang B, Tong C et al. · 2026 · Preprint
Abstract Objective: This study investigated post-SMILE changes in corneal refractive power, axial length, and anterior chamber depth, and examined the relationship between anterior chamber depth change and corneal ablation depth. Biometric…
View details →Yan Z, Chen T, Ma X et al. · 2026 · Psychology research and behavior management
Purpose Impaired cognitive flexibility is a core feature of obsessive-compulsive disorder (OCD) and may contribute to symptom persistence and variabe therapeutic outcomes. However, traditional measures may adequately capture how cognitive…
View details →Pérez-Bellido A, Duato D, Giannelli F et al. · 2026 · Journal of experimental psychology. Learning, memory, and cognition
Statistical learning is the process of extracting regularities from the environment. Although sequential cross-modal regularities are ubiquitous (e.g., the sight of a falling ball followed by the sound of impact), previous research has…
View details →Cuccia F, Cracchiolo AN, Piras A et al. · 2026 · Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Background Radiotherapy (RT) is a cornerstone in cancer management, but late radiation tissue injury (LRTI) remains a relevant clinical issue, affecting approximately 5% of patients and significantly impacting quality of life. Hyperbaric…
View details →Samuels S, Seaton M, Abdel-Rahman SM et al. · 2026 · Therapeutic innovation & regulatory science
Background Legislative initiatives have spurred an increase in pediatric drug development programs. However, some drug products studied in the pediatric population have not received an approved pediatric indication, and efforts have been…
View details →Koncz S, Pothorszki D, Papp N et al. · 2026 · British journal of pharmacology
Background and purpose Ketamine consists of two enantiomers, (R)-ketamine and (S)-ketamine, which exhibit distinct pharmacological properties. Currently, only the (S)-enantiomer has been approved for the treatment of major depressive…
View details →Boisseau W, Darsaut TE, Raymond J · 2026 · Neuro-Chirurgie
Background Non-inferiority (NI) trials are essential to evaluate whether new treatments which may offer some collateral benefit (such as less invasiveness, fewer side effects, availability, ease of administration, or lower cost) do so…
View details →Tolarba JE, Cerniglia L, Hewitt DA et al. · 2025 · Nurse education in practice
Aim This study examined the impact of fully immersive virtual reality (FIVR) on knowledge, decision-making, self-efficacy and engagement compared with traditional onboarding methods. Background Newly graduated nurses often face challenges…
View details →Longo G, Pacchiarotti G, Pizzigallo C et al. · 2026 · Journal of orthopaedic surgery and research
Introduction The introduction of computer-assisted navigation (CAS) in total knee arthroplasty (TKA) aimed to improve prosthetic alignment and potentially enhance long-term implant survival. However, the actual clinical benefit beyond 10…
View details →Yoshida K, Hakozaki T, Hasegawa T et al. · 2025 · Journal of clinical monitoring and computing
The aim of the present study was to investigate the utility of the intraoperative high frequency variability index (HFVI) / Analgesia Nociception Index (ANI) for predicting postoperative pain in patients undergoing open liver or pancreatic…
View details →Lemoine L, Adam V, Salleron J et al. · 2025 · Brachytherapy
Purpose Removal of brachytherapy applicator is routinely performed under premedication including Kalinox® gas inhalation without general anesthesia. The applicator removal is nevertheless associated with discomfort, anxiety or pain. We…
View details →Özkaya AB, Ghaseminejad Y · 2025 · FEBS open bio
Autophagy plays a critical role in maintaining cellular homeostasis and is implicated in various physiological and pathological processes, including cancer, neurodegeneration, and metabolic disorders. Although typically associated with…
View details →Lee JW, Kim CJ, Lee BK et al. · 2025 · JACC. Advances
Background Distal radial access (DRA) has emerged as an alternative to transradial access (TRA) in coronary procedures. However, evidence supporting its use in ST-segment elevation myocardial infarction (STEMI) remains limited. Objectives…
View details →El-Hajj VG, El Choueiri J, Vasella F et al. · 2026 · Brain & spine
Introduction Central nervous system (CNS) melanocytomas are rare, pigmented tumors derived from leptomeningeal melanocytes. Although generally benign, they can exhibit locally aggressive behavior and recur. Despite increasing recognition,…
View details →Barber D, Wijeratne T, Singh L et al. · 2025 · Life (Basel, Switzerland)
Sporadic Parkinson's Disease (PD) affects 3% of people over 65 years of age. People are living longer, thanks in large part to improvements in global health technology and health access for non-neurological diseases. Consequently,…
View details →Lazarevic Lindblad M, Pålsson E, Lazarevic V et al. · 2026 · Infection prevention in practice
Background Central venous catheters (CVCs) are commonly used in patients with haematological diseases but are associated with infectious complications. The CVC Anti-infection Double Lumen Bundle was introduced in December 2020 to reduce…
View details →Sunwoo JS, Cho YW, Shin WC et al. · 2025 · Journal of clinical neurology (Seoul, Korea)
Background and purpose To evaluate the clinical efficacy and safety of pregabalin in Korean adults with restless legs syndrome (RLS). Methods In this randomized, multicenter, double-blind, placebo-controlled trial, 78 patients with RLS…
View details →Gaeini Z, Mirmiran P, Azizi F · 2026 · Scientific reports
While emerging evidence from Western populations suggests that higher carbohydrate quality (assessed by indices incorporating fiber, glycemic index, whole grains, and solid carbohydrate sources) is inversely associated with cardiovascular…
View details →Soral S, Bargale S, Dave B et al. · 2026 · Journal of the Indian Society of Pedodontics and Preventive Dentistry
Background Orthodontic treatment has long been associated with visible wires in the mouth. Clear aligners, once limited to mild crowding/spacing, are now supported for correcting more complex malocclusions. While Clear Aligner Therapy…
View details →Manca A, Palermiti A, Corcione S et al. · 2026 · Antibiotics (Basel, Switzerland)
Background/Objectives: Cefiderocol (FDC) is a siderophore-containing cephalosporin that retains activity against many β-lactamase-producing bacteria, such as New Delhi metallo-β-latamase-producing (NDM) K. pneumoniae . Its use in…
View details →刘芳1，吴苏喜1，2，蒋明芳1，谭传波3，李普选2LIU Fang1, WU Suxi1,2, JIANG Mingfang1, TAN Chuanbo3, LI Puxuan2 · 2022 · Zhongguo youzhi
为了了解不同制油工艺对油茶籽油生物活性成分含量和抗氧化活性的影响，以油茶果为原料，采取鲜榨法、浸提法、新水法、冷榨法和热榨法5种制油工艺分别制取油茶籽油，研究对比了5种制油工艺的提油率，所制取的油茶籽油的脂肪酸组成、生物活性成分(生育酚、角鲨烯及多酚)含量及其对DPPH自由基和ABTS自由基的清除能力。结果表明，5种制油工艺的提油率均在73%以上，其中浸提法（（96.45±3.02）%）最高，冷榨法（（73.72±2.76）%）最低，鲜榨法（（82.36±224）%）、新水法（（81.91±3.21）%）和热榨法（（80.34±2.09）%）没有显著差异；5种工艺所制取的油茶籽油具有相似的脂肪酸组成；在α-生育酚和总生育酚含量方面，新水法制取的油茶籽油含量最高（α-生育酚含量（263.77±1.58）mg/kg，总生育酚含量（280.55±1.64）mg/kg），鲜榨法、冷榨法和热榨法制取的油茶籽油中总生育酚含量接近，在233~244 mg/kg之间，浸提法制取的油茶籽油中总生育酚含量只有（17.10±0.76）mg/kg；在角鲨烯和多酚含量方面，鲜榨法制取的油茶籽油明显高于其他工艺的，分别为（350.56±7.60）mg/kg和（45.04±4.50）mg/kg，新水法制取的油茶籽油角鲨烯含量最低，为（249.99±3.73）mg/kg，浸提法制取的油茶籽油多酚含量最低，为（7
View details →Muhammad Abba Isah Audu, Yusuf Idris, Muhammad Liman Muhammad et al. · 2022 · Botanica
The nutritional attributes of sesame, Sesamum indicum, vary substantially and are primarily influenced by the plant’s genetic makeup. This investigation accessed the biochemical composition of sesame mutants from two generations. Seeds of eleven M3 lines were planted in a Randomized Complete Block Design (RCBD) to raise M4 lines, which were advanced to M5 generation. The seeds were harvested at maturity, and their biochemical compositions were quantitatively determined following standard procedures. Results revealed significant differences (p 0.05) was observed in ash content of M4 and M5 muta
View details →Xiao-Xiao Han, Jia Qiao, Zhan-Ao Meng et al. · 2023 · Brain Sciences
Objectives: Investigate the biomechanical characteristics in tracheostomized patients with aspiration following acquired brain injury (ABI) and further explore the relationship between the biomechanical characteristics and aspiration. Methods: This is a single-center cross-sectional study. The tracheostomized patients with aspiration following ABI and age-matched healthy controls were recruited. The biomechanical characteristics, including velopharynx (VP) maximal pressure, tongue base (TB) maximal pressure, upper esophageal sphincter (UES) residual pressure, UES relaxation duration, and subgl
View details →Deng, Zhu, Cao et al. · 2026 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
The clinical evaluation of lumbar degenerative disease (LDD) severity relies on symptoms and imaging, lacking biologically specific diagnostic markers. This study investigated the role of serum complements in LDD to assess their potential…
View details →Xiuwen Sun, Xiaoling Li, Lingyu Ji et al. · 2018 · PeerJ
Based on the existing research on sound symbolism and crossmodal correspondence, this study proposed an extended research on cross-modal correspondence between various sound attributes and color properties in a group of non-synesthetes. In Experiment 1, we assessed the associations between each property of sounds and colors. Twenty sounds with five auditory properties (pitch, roughness, sharpness, tempo and discontinuity), each varied in four levels, were used as the sound stimuli. Forty-nine colors with different hues, saturation and brightness were used to match to those sounds. Result revea
View details →QIAN Ren-dong, WANG Lian-sheng, LUO Qiao-hua et al. · 2023 · Siliao yanjiu
The purpose of the study was to investigate the effects of wheat gluten replacing fish meal on growth performance, serum biochemistry, liver antioxidant and intestinal digestive enzyme activities of Cyprinus carpio . A total of 180 healthy Cyprinus carpio with an initial body weight of (9.16±0.03) g were selected and divided into three experimental groups, with three replicates in each group and 20 fish in each replicate. The control group (CW) was with 5% fish meal, and the experimental groups were with 50% (WA) and 100% (WB) fish meal replaced by wheat gluten. The experiment lasted for 56 d.
View details →Hang Wang, Xiaojie Qin, Xia Li et al. · 2020 · Poultry Science
This study was conducted to investigate the effects of air chilling (AC), water chilling (WC), combined chilling consisting of WC for 20 min and AC (CO20), and combined chilling consisting of WC for 30 min and AC (CO30) on the microbiological status, surface color, processing yield, and moisture content of yellow-feathered chicken carcasses. After chilling, the carcasses treated by AC exhibited the highest total viable counts (TVC) (4.7 cfu/cm2), followed by those treated by CO20 and CO30, whereas the carcasses treated by WC showed the lowest (P 0.05) was found among the carcasses treated by C
View details →ّForough Farshidmanesh, Hosein Davoudi, Hasan Heidari et al. · 2019 · Taḥqīqāt-i ̒Ulūm-i Raftārī
Aim and Background: Many women begin their marital life with high intimate relationships, but with time, these intimate relationships are becoming less and more difficult, and it is just when then couple burnout has begun. The purpose of this study was to comparison of the effectiveness of mindfulness education and Emotional Focused Therapy (EFT) on couple intimacy, commitment and happiness women with couple burnout. Methods and Materials: The semi-experimental study was performed as pretest-posttest with a control group. The population included all women with couple burnout who was referred t
View details →