19,840 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Ogasawara F, Minami Y, Chi S et al. · 2026 · International journal of hematology
Mutant TP53 (mTP53) variants are diverse, and residual wild-type p53 function (functional, non-functional), gain-of-function (GOF) mTP53, and the number of mTP53 (single-hit, multi-hit) can affect prognosis. We used next-generation…
View details →Galvan M, Fujitani M, Dushime J et al. · 2026 · Preprint
β2-Adrenergic receptor ( Adrβ2 ) is the most abundant form of adrenergic receptors in skeletal muscle. Our previous studies have shown that the ventromedial hypothalamic nucleus (VMH) regulates metabolic benefits of exercise, potentially…
View details →Fattahi Z, Talakesh T, Kheiri S et al. · 2026 · Recent advances in inflammation & allergy drug discovery
Introduction/objective In children affected by allergic proctocolitis, impaired weight gain and developmental failure to thrive can be a prominent manifestation. However, it remains unclear whether the association between White Blood Cell…
View details →Baillon A, Bleichrodt H, Granic GD · 2026 · Medical decision making : an international journal of the Society for Medical Decision Making
BackgroundHealth state utility measurements are central in health policy and medical decision making. Common methods are the standard gamble (SG) and the time tradeoff (TTO). They typically use hypothetical questions. It is unknown whether…
View details →Kim DI, Lagravère MO, Almeida F et al. · 2026 · The Angle orthodontist
Objectives To characterize functional changes of the airway while wearing an appliance simulating severe arch constriction using level 3 polysomnography. Materials and methods For this pilot, single-blinded prospective randomized…
View details →Fröhlich F, Mentesana L, Deimel C et al. · 2026 · Preprint
Capturing and handling wild animals is essential for ecological and evolutionary research, yet their effects on physiology, behaviour, and reproductive success remain poorly understood. We investigated short-and longer-term consequences of…
View details →Zheng Y, Chen L · 2026 · Preprint
Perceptual processing integrates information from multiple sensory modalities to form a coherent representation of the environment. A classic example of such is the Sound-Induced Flash Illusion (SIFI), where the perceived number of visual…
View details →Nakamura M, Nishioka Y, Akamatsu N et al. · 2026 · Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
Biliary cast syndrome (BCS) remains a significant concern that can lead to graft failure and mortality. Data on the etiology and outcomes are limited, particularly with regard to the differences in the risk of occurrence of BCS between…
View details →Bottura RM, Fassone M, Avanzino L et al. · 2026 · Neuroscience
Previous studies on motor imagery (MI) suggest that the more similar the imagined and actual movement contexts are, the better the imagery quality. Thus, one might hypothesize that for movements performed within a medium, MI is more…
View details →Ullah S, Subhan G, Shakir L et al. · 2026 · Preprint
Abstract Allelopathy involves the release of bioactive compounds from plants that influence the germination and growth of surrounding species. Limited evidence exists on the allelopathic effects of common weeds on wheat germination. This…
View details →Ganeyan A, Ganesh CB · 2026 · Neuropeptides
Galanin (GAL), a neuropeptide produced in both the central and peripheral nervous systems, is implicated in various physiological processes, including reproduction in vertebrates. Yet, the role of GAL is not understood in reptilian…
View details →Alencar TS, Santos MO, Schneider VMM et al. · 2026 · Brain research
Systemic inflammation triggers a set of physiological and behavioral changes known as sickness behavior, including fever and hypolocomotion. Previous studies demonstrated that lipopolysaccharide (LPS) induces these responses in both sexes,…
View details →Fonseca AJM, Cabrita ARJ · 2026 · JDS communications
This study evaluated the effects of replacing soybean hulls with exhausted olive pomace (EOP) on feed intake, milk production and composition, and rumen fermentation parameters. A cyclical changeover design experiment was used with 4…
View details →Muroi M, Fukuda S, Takahashi M et al. · 2026 · The Journal of reproduction and development
Our previous study in hamsters indicated that progesterone (P) induces enhancement of spermatozoal hyperactivation, while 17β-estradiol (Eβ) and γ-aminobutyric acid (GABA) suppress this enhancement. Since P has also been shown to enhance…
View details →De Bruyn L, Van Beek F, Vander Perre S et al. · 2026 · Molecular and cellular endocrinology
Background Sepsis HDL- and LDL-hypocholesterolemia associate with adverse outcomes, but whether this necessitates supplementation or merely reflects disease severity remains unclear. We hypothesize that sustained hypocholesterolemia can…
View details →Gao J, Savegnago CG, Marins TN et al. · 2026 · Journal of dairy science
This study evaluated the effects of different vaccination schedule and oral administrating a nonsteroidal anti-inflammatory drug (NSAID) around dry-off on systemic inflammation, immune responses, behaviors during the early dry period, and…
View details →Gackowska K, Krejmer-Rabalska M, Drazkowska K et al. · 2025 · Virology
Virus-like particles (VLPs) have long been utilized as immunogens to prevent infectious diseases. Particles derived from the small surface proteins of the hepatitis B virus (sHBsAg) can self-assemble into small, highly immunogenic…
View details →Hashimoto N, Wakimoto Y, Kusama T et al. · 2026 · Therapeutic drug monitoring
Background Pycsim, a dosing software for linezolid (LZD) based on Bayesian estimation, predicts dosing in the therapeutic drug monitoring (TDM) of LZD. However, its predictive performance, examined using an independent data set with a…
View details →Ching ASM, Kim J, Davis C · 2025 · Preprint
This preregistered study investigated whether linguistic information can influence low-level visual perception. We argue that many previous studies supporting this view have significant shortcomings. Specifically, these studies conflate…
View details →Lou Y, Yang T, Xia C et al. · 2026 · Molecular and cellular endocrinology
Steroid hormone synthesis in granulosa cells (GCs) is crucial for normal follicular development and ovulation. Emerging evidence suggests that copper (Cu), a trace element, influences hormone secretion in yak granulosa cells (YGCs);…
View details →Alipour A, Ganjkhanlou M, Zali A et al. · 2026 · Scientific reports
The pre-weaning period is critical because early-life nutrition and management influence growth, metabolic function and Rumen development, thereby affecting subsequent productivity in dairy calves. Zinc (Zn) supplementation plays a key…
View details →Palacios-Duchicela R, Létourneau-Montminy MP, Lizardo R et al. · 2026 · Animal : an international journal of animal bioscience
Feeding strategies such as P and Ca depletion and repletion have been proposed to reduce the use of phosphate or improve P utilisation efficiency in pig diets, thereby contributing to the sustainability of the sector. A total of 48 entire…
View details →Zerlin RR, Elissetche JC, Avila-Sanchez JS et al. · 2025 · Journal of environmental management
Butterflies are important pollinators worldwide and are often sensitive indicators of ecosystem health. Prescribed fire is used in grassland to mimic historic wildfires, improve forage nutritional value, and increased forb production and…
View details →Sarimehmetoglu N, Simsek H · 2026 · The International journal of prosthodontics
Purpose To evaluate the fracture resistance of primary tooth crowns fabricated at different thicknesses using two different 3D-printing technologies: stereolithography (SLA) and digital light processing (DLP). Materials and methods A…
View details →Sawamoto A, Shiba M, Okuyama S et al. · 2026 · The Journal of pharmacy and pharmacology
Objectives Cynandione A (CA), a major bioactive compound isolated from Cynanchum wilfordii Radix, is a crude drug traditionally used in East Asia. We have previously demonstrated that CA induces a beige adipocyte-like phenotype in vitro.…
View details →Stock A, Adaniya C, Gaines M et al. · 2026 · Urogynecology (Philadelphia, Pa.)
Importance Urethral Bulkamid is a U.S. Food and Drug Administration-approved nonsurgical treatment for stress urinary incontinence and stress-predominant mixed urinary incontinence due to intrinsic sphincter deficiency. This procedure is…
View details →Deng SM, Chen YJ, Hung WC et al. · 2026 · Translational psychiatry
Anxiety is a common mental health disorder marked by heightened stress responses and impaired emotional regulation. While the hippocampus and the hypothalamic-pituitary-adrenal (HPA) axis play key roles in regulating anxiety, the molecular…
View details →Ching ASM, Kim J, Davis C · 2025 · Preprint
This preregistered study investigated whether linguistic information can influence low-level visual perception. We argue that many previous studies supporting this view have significant shortcomings. Specifically, these studies conflate…
View details →Najafi A, Nosaka K, Javidi M et al. · 2026 · Journal of strength and conditioning research
Abstract Najafi, A, Nosaka, K, Javidi, M, Naddafha, S, Kumagawa, D, Bertochi, GFA, and Latella, C. Acute effects of accentuated eccentric loading in comparison to traditional resistance loading on velocity and other parameters in…
View details →Goonasekera MA, Malijan GB, Sardell RJ et al. · 2026 · American journal of nephrology
Introduction Sacubitril/valsartan shows benefits in heart failure and may have kidney protective effects. Its impact on kidney tubular health in chronic kidney disease (CKD) remains unclear. We evaluated the effects of sacubitril/valsartan…
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