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Browse the failure-mode index

19,840 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result Report

Is There a Significant Association Between Body Image and Psychological Health in Moroccan Postmenopausal Women? A Cross-Sectional Study

Sara Esseffar, Said Bellahcen, Ghizlane Azizi et al. · 2025 · The Open Public Health Journal

Background Menopause and its consequences, sometimes complex, can generate discomfort in well-being and consequently affect the quality of women’s lives. Objective The present study was carried out to examine the quality of life of…

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Negative / Null Result Report

Abstract 10858: Significant Association Between Washout Ratio of Renal 123i-metaiodobenzylguanidine and Muscle Sympathetic Nerve Activity in Patients With Hypertension

Yoshitaka Okabe, Hisayosi Murai, souichiro usui et al. · 2015 · Circulation

Background: Simplicity HTN-3 trial showed the negative result for renal denervation (RDN) in patient with resistant hypertension. One of limitations was that no appreciate evaluation of renal sympathetic nerve activity (RSNA) was applied…

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Negative / Null Result Report

LACK OF SIGNIFICANT ASSOCIATION BETWEEN COMPONENT ALIGNMENT AND FUNCTIONAL OUTCOME IN TOTAL HIP ARTHROPLASTY

Ismail Hadisoebroto Dilogo, Wildan Latief, Muh Trimugroho Fahrudhin · 2018 · Journal of Southeast Asian Medical Research

Background : Total hip replacement (THR) failure isinfluenced bythe prosthesis component orientation. The debate is still ongoing to determine the best angles for acetabular or femoral components. Objective :To evaluate the functional…

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Negative / Null Result Report

No significant association between 40bp ins/del promoter polymorphism of MDM2 and breast cancer susceptibility in Pakistani women

Sania Gull, Nabeela Tariq, Hamida Ali et al. · 2025 · LIAQUAT MEDICAL RESEARCH JOURNAL

Breast cancer remains the most prevalent malignancy among women, and is the second leading cause of mortality worldwide. Genetic heterogeneity in the MDM2 promoter region has been associated with increased cancer susceptibility. The study…

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Negative / Null Result Report

No significant association between term premature rupture of membranes and neonatal APGAR score: A cross-sectional study

Shelvy Era Chintia, Henidekasari, Veronica Ela Rimawati et al. · 2025 · Jurnal Ilmiah Kesehatan Sandi Husada

Introduction: Premature rupture of membranes (PROM) is defined as the rupture of the amniotic sac before the onset of labor, potentially increasing the risk of infection, hypoxia, and a low APGAR score in newborns. The APGAR score assesses…

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Negative / Null Result Report

No significant association between term premature rupture of membranes and neonatal APGAR score: A cross-sectional study

Shelvy Era Chintia, Henidekasari Henidekasari, Veronica Ela Rimawati et al. · 2025 · Jurnal Ilmiah Kesehatan Sandi Husada

Introduction: Premature rupture of membranes (PROM) is defined as the rupture of the amniotic sac before the onset of labor, potentially increasing the risk of infection, hypoxia, and a low APGAR score in newborns. The APGAR score assesses…

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Negative / Null Result Report

Non-invasive right ventricular myocardial work in patients with significant tricuspid regurgitation: association with etiology and outcome

Y Obayashi, S C Butcher, X Galloo et al. · 2026 · European Heart Journal - Cardiovascular Imaging

Abstract Background/Introduction Right ventricular (RV) function is a key factor in risk stratification of patients with tricuspid regurgitation (TR). Right ventricular myocardial work (RVMW) has been proposed as a novel echocardiographic…

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Negative / Null Result Report

No significant association between quadriceps tendon alignment and 1‐year patient‐reported outcomes following physiological total knee arthroplasty without patellar resurfacing

Manabu Akagawa, Roberto Berebichez‐Fridman, Loic Villet et al. · 2026 · Knee Surgery, Sports Traumatology, Arthroscopy

Abstract Purpose This study aimed to clarify the clinical relevance of quadriceps tendon alignment (QTA), focusing on the quadriceps tendon axial angle (QTAx), in patients undergoing ‘physiological total knee arthroplasty (TKA)’. This…

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Negative / Null Result Report

Association between postdischarge antibiotic use and C. difficile testing as a surrogate for clinically significant diarrhea

Daniel J. Livorsi, James Merchant, Hyunkeun Cho et al. · 2025 · Antimicrobial Stewardship & Healthcare Epidemiology

Abstract Objective: Postdischarge antibiotics are often sub-optimal or unnecessary. This study sought to measure the risk of diarrhea in recently hospitalized patients treated with postdischarge antibiotics Design: Retrospective cohort…

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Negative / Null Result Report

A174 TESTING FOR AND INCIDENCE OF CELIAC DISEASE AUTOIMMUNITY SAW SIGNIFICANT BUT TEMPORARY DECLINES DURING COVID-19 PANDEMIC

J A King, S Coward, G G Kaplan et al. · 2024 · Journal of the Canadian Association of Gastroenterology

Abstract Background Celiac disease (CD) is an autoimmune disorder with various complications and long-term health risks. The COVID-19 pandemic affected the entire healthcare system—including screening for and diagnosing non-infectious…

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Negative / Null Result Report

Lack of Association between Cholelithiasis and Significant Coronary Artery Disease: An Autopsy Study from Greece

Christos Soutis, Chara Spiliopoulou, Nikolaos Goutas et al. · 2022 · Journal of Advances in Medicine and Medical Research

Aims: Cholelithiasis or Gallstone disease and coronary artery disease have been reported to share several common risk factors. The aim of this study was to examine if there is an association between coronary artery disease (CAD) and…

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Negative / Null Result Report

Significant association of specific DRB1 & DQB1 sequence feature variant types with systemic sclerosis autoantibodies types and racial groups (159.20)

Richard Scheuermann, Nishanth Marthandan, Paula Guidry et al. · 2012 · The Journal of Immunology

Abstract The sequence feature variant type (SFVT) approach to genetic association analysis has previously identified parts of HLA proteins that are associated with development of a variety of autoimmune diseases. Using the SFVT approach,…

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Negative / Null Result Report

A200 HIGH-DEFINITION CHROMOENDOSCOPY RESULTS IN MORE SIGNIFICANT DYSPLASIA DETECTION THAN WHITE LIGHT ENDOSCOPY WITH RANDOM BIOPSIES IN ULCERATIVE COLITIS PATIENTS

T T Hoang, Y Leung, G Rosenfeld et al. · 2023 · Journal of the Canadian Association of Gastroenterology

Abstract Background Ulcerative colitis (UC) is an inflammatory bowel disease that results in inflammation of the colonic mucosa, leading to abdominal pain, rectal bleeding, weight loss, and diarrhea. This chronic inflammation results in a…

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Negative / Null Result Report

Role of Carotid Intima-Media Thickness and Carotid Plaque in Predicting Significant Coronary Artery Stenosis in Thai Patients with Chronic Coronary Syndrome: A Cross-Sectional Study

· 2022 · Journal of the Medical Association of Thailand

Objective: To evaluate the diagnostic role of carotid artery intima-media thickness and plaque for significant coronary artery disease (CAD) in Thai patients with chronic coronary syndrome (CCS) when coronary angiography (CAG) was…

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Negative / Null Result Report

Association of postsystolic shortening on stress echocardiography and significant coronary artery stenosis: A single‐centre retrospective cohort study

Joel Toftgård, Henrik Hedskog, Lars Rune et al. · 2024 · Clinical Physiology and Functional Imaging

Abstract Background Postsystolic shortening (PSS) is one of the proposed quantitative measures to predict myocardial ischaemia in the stress echocardiographic (SE) evaluation. It is previously known that hypo‐/akinesia (HA) correlates well…

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Negative / Null Result Report

Association of TSH Levels in the Therapeutically Neglected Range of 6.5–8 mIU/L with Significant Changes in Liver and Kidney Function: A Retrospective Study of the Kashmiri Population

Tousief Ahmed, Ruqaya Aziz · 2022 · Sudan Journal of Medical Sciences

Background: The thyroid gland secretes hormones crucial for growth, differentiation, regulation of metabolic processes, and homeostasis. In response to underactivity of this gland, the pituitary secretes thyrotropin, also known as the…

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Negative / Null Result Report

Lack of Significant Association between Stromal Tumor-Infiltrating Lymphocytes (TILs) and 2014 FIGO Stage in Epithelial Ovarian Cancer: A Cross-Sectional Study

Amanda Putri, Aswiyanti Asri, Puja Agung Antonius · 2026 · JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga

Highlights: Understanding the relationship between TIL infiltration and tumor stage could refine prognostic models and guide targeted therapies. Tumor-infiltrating lymphocytes density is considered an essential immune marker in ovarian…

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Negative / Null Result Report

A192 CONSUMPTION OF FOOD LOWER IN TRYPTOPHAN IS ASSOCIATED WITH SIGNIFICANT ANXIETY IN PATIENTS WITH CELIAC DISEASE

V Gupta, A Jivraj, D Armstrong et al. · 2022 · Journal of the Canadian Association of Gastroenterology

Abstract Background Tryptophan, an essential amino acid found in many protein-based foods, has been involved in the pathogenesis of mood disorders and celiac disease (CeD). However, dietary tryptophan consumption has not been investigated…

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Negative / Null Result Report

Heparinized venous blood gas syringes are associated with a significant decrease in measured packed cell volume in dogs due to hemodilution

Coyne M. Hopey, Dana Caldwell, Erin Binagia et al. · 2025 · Journal of the American Veterinary Medical Association

Abstract OBJECTIVE To assess the effect of hemodilution on PCV when commercial preheparinized venous blood gas (PH-VBG) syringes are used compared to directly filled Hct tubes, and to evaluate the impact of delayed centrifugation on PCV.…

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