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Browse the failure-mode index

20,217 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Pre-processing and thermal treatment modulate structure, solubility and digestibility of faba bean protein isolates: A structure–function perspective

Sharma N, Gwala S, Owens RA et al. · 2026 · Food Hydrocolloids.

Despite growing interest in faba bean (Vicia faba L.) as a sustainable plant protein source, limited studies address process-induced structural mechanisms linking functionality with gastro-intestinal (GI) digestion. This study elucidates…

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Negative / Null Result ReportMedicine

Do steroids improve outcomes of idiopathic sixth nerve palsy in children?

Sternfeld A, Goren L, Ehrenberg M et al. · 2026 · Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

Purpose To analyze the effect of systemic steroid treatment in children with benign acquired isolated sixth nerve palsy (BAISNP) regarding healing, recurrence risk and late sequelae. Methods A retrospective cohort design was used. The…

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Negative / Null Result ReportMedicine

Combined Hormonal Contraception with Low-Dose Ethinylestradiol is Associated with Modest Reduction of Breast Milk Volume when Administered Vaginally, but Not Orally.

Segev L, Weitzman G, Hijazi B et al. · 2026 · Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine

Background Combined hormonal contraception (CHC) is habitually not prescribed to breastfeeding women due to concerns of decreased milk production. This habit is based on inconclusive studies that examined lactation suppression of CHC with…

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Negative / Null Result ReportMedicine

Biomechanical assessment of intraocular lens stability and position based on suture and inlet variations in the Canabrava double-flanged technique.

Suh YK, Choi S, Yoon CK et al. · 2026 · Journal of cataract and refractive surgery

Purpose To evaluate how variations in suture type, suture length, and scleral outlet angle affect intraocular lens (IOL) positioning and fixation stability in the Canabrava technique, given ongoing concerns such as iris chafing and the…

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Negative / Null Result ReportMedicine

Differences in Cyclotorsion Compensation Between Low, Medium, and Large Angles in Myopic PRK: Visual and Refractive Results.

Ben Ephraim Noyman D, Safir M, Sommer A et al. · 2026 · Journal of refractive surgery (Thorofare, N.J. : 1995)

Purpose To evaluate the differences in myopic photorefractive keratectomy (PRK) outcomes between small, medium, and large cyclorotational angle degrees. Methods This retrospective comparative study was conducted at Care Vision Laser…

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Negative / Null Result ReportMedicine

Accuracy of Continuous Glucose Monitoring in Adults With Postbariatric Hypoglycemia After Roux-en-Y Gastric Bypass Surgery Under Stable and Dynamic Glucose Conditions.

Lizoain A, Vettoretti M, Ferreira A et al. · 2026 · Diabetes care

Objective Although continuous glucose monitors (CGMs) are increasingly used to detect and manage postbariatric hypoglycemia (PBH) and associated glucose variability, data on their accuracy in this population remain scarce. Research design…

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Negative / Null Result ReportMedicine

Myocardial expression of <i>ADGRL4</i> and <i>AQP7</i> is related to regression of left ventricular hypertrophy after aortic valve replacement in a sex-dependent manner.

Halldórsson KB, Karagianni K, Leite-Moreira AF et al. · 2026 · American journal of physiology. Heart and circulatory physiology

Aortic stenosis (AS) may lead to left ventricular (LV) hypertrophy (LVH). After aortic valve replacement (AVR), LVH often does not regress fully. This has been associated with a worse prognosis. This study aimed at comparing LVH regression…

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Negative / Null Result ReportOpen accessMedicine

Migraine as an occupational health risk among nurses in Qassim region, Saudi Arabia: a multicenter study of risk perceptions and associated factors.

Qalawa SAA, Elbqry MG, Elmansy FM et al. · 2026 · Frontiers in public health

Background Migraine is a common neurological disorder and an emerging occupational health risk among nurses due to demanding workloads, shift work, workplace stress, and prolonged screen exposure. Understanding nurses' risk perceptions of…

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Negative / Null Result ReportOpen accessMedicine

The Relationship between Perceived Food Environment and Glycemic Control Among Malaysian Diabetic Patients.

Berahim AS, Rohana AJ, Yaacob NM et al. · 2026 · International journal of preventive medicine

Background The perceptions of diabetic patients on their food environment influence their dietary choices and would impact glycemic control. The main aim of this study was to determine any relationship between perceived food environment…

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Negative / Null Result ReportMedicine

Interspecific patterns of variation in dental growth increments of crocodilians.

Hogg R · 2026 · Developmental dynamics : an official publication of the American Association of Anatomists

Background Multiple studies have supported the hypothesis that incremental growth lines in crocodilian dentin are analogous with circadian von Ebner's lines in mammals; however, variation in these growth lines has been largely unstudied.…

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Negative / Null Result ReportMedicine

Cloning-based analysis of MHC class II DRB variation and Enterocytozoon bieneusi association in the Amur tiger (Panthera tigris altaica).

Liu Y, Xu H, Zhang Y et al. · 2026 · Molecular and biochemical parasitology

The polymorphism of major histocompatibility complex (MHC) class II classical genes is closely related to pathogen resistance, among which the second exon of the DRB gene has the highest variability. In this study, we analyzed exon 2 of…

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