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WASTE Journal

Browse the failure-mode index

19,830 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Associations of new intracranial haemorrhage, ischaemic stroke and survival with dual antiplatelet therapy regimen or duration after endovascular treatment for ruptured cerebral aneurysm.

Perng PS, Chang Y, Chuang MT et al. · 2026 · Stroke and vascular neurology

Background Dual antiplatelet therapy (DAPT) is often necessary following endovascular treatment for ruptured cerebral aneurysms; however, the optimal drug combination and treatment duration remain uncertain. Method Patients with…

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Negative / Null Result ReportOpen accessMedicine

Association Between MTHFR Gene Polymorphisms and Subclinical Hypothyroidism in Early Pregnancy: A Retrospective Case-Control Study.

Liu L, Wang C, Chen X et al. · 2026 · International journal of women's health

Objective To investigate the association between methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and subclinical hypothyroidism (SCH) in early pregnancy. Methods This retrospective case-control study included 100 pregnant…

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Negative / Null Result ReportMedicine

[Effects of oliceridine versus sufentanil for anesthesia induction and postoperative analgesia on postoperative nausea and vomiting in patients undergoing gynecological laparoscopic surgery: a randomized controlled trial].

Wang Y, Xu X, Shen WJ et al. · 2026 · Zhonghua yi xue za zhi

Objective: To investigate the effects of oliceridine versus sufentanil for anesthesia induction and postoperative patient-controlled intravenous analgesia (PCIA) on postoperative nausea and vomiting (PONV) in patients undergoing…

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Negative / Null Result ReportOpen accessMedicine

Erenumab and OnabotulinumtoxinA in Chronic Migraine: A Comparative Analysis.

Garcés-Pellejero M, Torres-Ferrús M, Mas-de-Les-Valls R et al. · 2026 · European journal of neurology

Objectives To compare response (reduction in headache frequency and differences in patient-reported outcomes) between Erenumab and OnabotulinumtoxinA from two phase-IV trials after 6 months of treatment. Materials/methods A prospective…

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Negative / Null Result ReportMedicine

Effect of the Multicomponent Exercise Program MoveUS on the Kinematic Fatigue of People With Glenohumeral Instability: A Secondary Analysis From a Randomized Controlled Trial.

Ramírez-Pérez L, Cuesta-Vargas AI · 2026 · Physiotherapy research international : the journal for researchers and clinicians in physical therapy

Kinematic movement analysis is highly relevant in patients with glenohumeral instability, a pathology characterized by fatigue-induced slowing of repetitive movements. However, the optimal exercise approach for this symptom remains…

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Negative / Null Result ReportOpen accessMedicine

Fecal microbiota composition concerning body mass index and early-life factors in Mexican preschool-aged children: a cross-sectional study.

Hernández-Rodríguez D, Contreras A, Melgar Lalanne G et al. · 2026 · PeerJ

Background The gut microbiota maturation extends beyond the first two years of life. Early perinatal and postnatal factors may influence the child's nutritional status, which, in turn, can affect the composition of their gut microbiota.…

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Negative / Null Result ReportOpen accessMedicine

Effect of a One-Week Lubricant Pretreatment on Post-LASIK Dry Eye: Single-Center Randomized, Single-Masked Study With 1-Month Follow-Up.

Cañones-Zafra R, Allendes-Urquiza G, Muñiz C et al. · 2026 · Journal of ophthalmology

Purpose Our purpose is to report the results of a prospective study on ocular discomfort and objective tear film parameters (osmolarity and NIKBUT), in myopic patients, and observe the possible differences at 1 month between randomized…

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Negative / Null Result ReportMedicine

Could Autism Spectrum Disorder Be Associated With Craniosynostosis?

Still MEH, Alberts A, Nagda P et al. · 2026 · The Journal of craniofacial surgery

Introduction Craniosynostosis is a common pediatric condition that results in variable symptoms that range from asymptomatic cosmetic deformities to severe signs of intracranial hypertension. Little is understood about the relationship…

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Negative / Null Result ReportMedicine

Immersive Haptic Simulation for Psychomotor Skill Acquisition in Preclinical Prosthetic Dentistry: A Randomized Study.

Bandiaky ON, Volteau C, Bihan A et al. · 2026 · The International journal of prosthodontics

Purpose The aim of this study was to evaluate the effect of using the VirTeaSy Dental simulator in conjunction with a virtual reality headset on student performance in conventional fixed prosthodontics simulations. Material and methods The…

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Negative / Null Result ReportOpen accessMedicine

Does closed suction drainage reduce postoperative hematoma and muscle swelling after total hip arthroplasty? A retrospective comparative study using computed tomography.

Asano T, Uemura K, Higuchi R et al. · 2026 · Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs

Purpose Closed suction drainage has been used after total hip arthroplasty (THA) to prevent hematoma, muscle swelling, and complications, but its effectiveness remains controversial. This study evaluated the effects of drains on…

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Negative / Null Result ReportMedicine

Constrained acetabular liner total hip arthroplasty versus conventional hemiarthroplasty for unstable comminuted femoral intertrochanteric fractures in elderly patients with neurological disorders.

Dong M, Liu Y, Wei C · 2026 · BMC surgery

Background To evaluate whether constrained acetabular liners (CAL) used in total hip arthroplasty (THA) reduce the risk of dislocation and related complications in patients with neuromuscular disorders and unstable comminuted femoral…

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Negative / Null Result ReportMedicine

Comparison of Nasal Tip Projection and Rotational Stability between Structural Rhinoplasty with Strut Graft and Preservation Rhinoplasty with Pitanguy Ligament Graft.

Farhadi F, Ahmadpour F, Nezafati S et al. · 2026 · Aesthetic plastic surgery

Background and aim The nasal tip plays a central role in facial aesthetics, and achieving long-term tip stability is a key objective in rhinoplasty. This study compared postoperative tip stability between structural rhinoplasty using a…

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Negative / Null Result ReportOpen accessMedicine

A chlorine releasing solution as an alternative for dental biofilm control.

Telles PYV, Oliveira VC, Geng Vivanco R et al. · 2026 · Scientific reports

To evaluate the antibiofilm activity of a chlorine-releasing solution (CRS) and its in vitro effects on enamel color stability, surface roughness, and microhardness. A mixed biofilm composed of Staphylococcus aureus, Candida albicans, and…

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Negative / Null Result ReportOpen accessMedicine

Comparison of Postoperative Analgesic Efficacy of Two Intrathecal Morphine Doses (75 μg vs 100 μg) for Cesarean Delivery: A Double-Blind Randomized Study.

Veraza JA, Martinez MA, Angulo P et al. · 2026 · Cureus

Background Intrathecal morphine remains a cornerstone of post-cesarean analgesia due to its prolonged spinal effect; however, its use is limited by dose-dependent adverse effects. Contemporary practice trends favor dose minimization, yet…

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Negative / Null Result ReportOpen accessMedicine

Do the Pre-Existing Class III and Class V Composite Restorations Affect the Sealing Ability and Integrity of 3D-Printed Laminate Veneer Margins? An In Vitro Study.

Qaraghuli AM, Cagidiaco EF, Ferrari M · 2026 · Journal of functional biomaterials

Background: The application of veneer restorations over previously composite-restored anterior teeth presents significant clinical challenges, particularly in achieving optimal marginal sealing. Aim: This in vitro study aimed to evaluate…

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