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19,830 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Do intraoperative calcar fractures increase early complications or revisions in short stem total hip arthroplasty? A propensity score matching study.

Suksathien Y, Suarjui J, Tippimanchai T et al. · 2026 · International orthopaedics

Purpose Intraoperative calcar fracture (IOCF) can compromise initial stability, leading to stem subsidence and instability. We aimed to compare 2-year complications and revision rates between patients who sustained IOCF and matched…

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Negative / Null Result ReportMedicine

Perioperative risk factors predicting CSF leak and retethering following tethered cord release for complex spinal lipomas.

Chesney KM, McAbee JH, Balu A et al. · 2026 · Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

Purpose Tethered cord release (TCR) is typically well tolerated in children, but cerebrospinal fluid (CSF) leaks can occur postoperatively, with rates as high as 33%. The aim of this study was to determine perioperative risk factors…

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Negative / Null Result ReportMedicine

Pregnancy outcomes of gestational diabetes mellitus treated before versus after 24 weeks: A comparison of Carpenter-Coustan and IADPSG criteria.

Gorsagun S, Pruksanusak N, Geater AF · 2026 · International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

Objective To compare pregnancy outcomes between early and standard treatment of gestational diabetes mellitus (GDM) diagnosed using the Carpenter-Coustan criteria and to assess the impact of applying the International Association of…

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Negative / Null Result ReportMedicine

Comparison of surgical safety among different comprehensive treatment models for adenocarcinoma of esophagogastric junction: a single-center cohort study.

Dai H, Wang Y, Shan F et al. · 2026 · BMC gastroenterology

Background Neoadjuvant chemotherapy (NAC) and neoadjuvant chemoradiotherapy (nCRT) are increasingly used to treat adenocarcinoma of the esophagogastric junction (AEG). However, there is insufficient clinical evidence to compare surgical…

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Negative / Null Result ReportMedicine

The impact of coronary artery bypass grafting on the short- and long-term development and progression of diabetic retinopathy: A Danish national matched cohort study.

Maschoreck LG, Stokholm L, Pedersen FN et al. · 2026 · Acta ophthalmologica

Purpose Diabetic retinopathy (DR) is a frequent long-term complication of diabetes. While hemodynamic changes are known risk factors for DR, the effect of coronary artery bypass grafting (CABG) on the development of DR is poorly…

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Negative / Null Result ReportMedicine

Diabetes and Performance Status Predict Severe, Persistent Radiation Proctitis: Long-Term Endoscopic Findings From STELLAR Trial.

Wang N, Xu T, Li H et al. · 2026 · International journal of radiation oncology, biology, physics

Purpose To characterize the long-term endoscopic natural history of chronic radiation proctitis (CRP) and identify predictors of severe lesions in patients with locally advanced rectal cancer from the STELLAR study (NCT02533271) . Methods…

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Negative / Null Result ReportMedicine

Effect of 5-Aminosalicylate Dose Reduction or Withdrawal on Prognosis in Patients with Ulcerative Colitis Receiving Advanced Therapy: A Multicenter Retrospective Cohort Study.

Sano Y, Yagi N, Ito Y et al. · 2026 · Digestive diseases and sciences

Background and aims The role of 5-aminosalicylates (5-ASA) in maintaining remission in patients with ulcerative colitis (UC) receiving advanced therapy remains controversial. This study evaluated the safety and feasibility of 5-ASA…

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Negative / Null Result ReportMedicine

Outcomes for Labor Induction Compared With Expectant Management Among Women Receiving Hospital-Based, Midwifery-Led Care.

Smith DC, Gemkow JW, Shiferaw BA et al. · 2026 · Journal of midwifery & women's health

Introduction Use of labor induction has increased rapidly for medical and nonmedical reasons, raising questions about its impact on cesarean birth rates. With growing incidence of elective induction of labor (IOL) at 39 weeks, uncertainty…

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Negative / Null Result ReportMedicine

Dynamic tensile loading improves neotendon formation at moderate daily loading cycles, but impairs neotendon formation at high daily loading cycles.

Jenkins TL, Darden K, Pourdeyhimi B et al. · 2026 · Journal of biomechanics

Synthetic polymer scaffolds with aligned fibers permit engineered tendon development and the formation of an aligned, collagen rich matrix. However, many tissue engineered constructs cannot withstand physiologically relevant loads. Both…

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Negative / Null Result ReportMedicine

Addition of Preoperative Ultrasound To 4D-CT Increases Radiologist Confidence in Identifying Hyperfunctioning Parathyroid Glands.

Mohammadi S, Cunnane ME, Juliano AF et al. · 2026 · AJNR. American journal of neuroradiology

Background and purpose Four-dimensional CT (4D-CT) is a key imaging modality for preoperative localization of parathyroid adenomas in primary hyperparathyroidism. Ultrasound (US) is frequently added with the assumption that it enhances…

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Negative / Null Result ReportMedicine

Down syndrome birth rate post Dobbs decision: has it changed?

Santoro SL, Alvarado C, Tseng SY et al. · 2026 · Journal of perinatology : official journal of the California Perinatal Association

Objective In 2022, the U.S. Supreme Court decision on Dobbs v. Jackson Women's Health Organization changed abortion access. We evaluated birth rates of Down syndrome (DS) before and after the Dobbs decision hypothesizing similarity to…

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Negative / Null Result ReportMedicine

Impact of additional left atrial roof ablation for persistent atrial fibrillation using cryoballoon: the ICEBERG trial.

Ukita K, Egami Y, Sugino A et al. · 2026 · Clinical research in cardiology : official journal of the German Cardiac Society

Background Several studies have investigated the efficacy of additional left atrial (LA) roof ablation to pulmonary vein isolation (PVI) using cryoballoon for persistent atrial fibrillation (AF). However, the evidence from randomized…

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Negative / Null Result ReportMedicine

Association of Prior Antibiotic Use With Negative Surgical Bone Biopsy Cultures and Disease Recurrence in Diabetes-related Foot Osteomyelitis.

Aragón-Sánchez J, Víquez-Molina G, Aragón-Hernández J et al. · 2026 · Advances in skin & wound care

Objective The authors hypothesized that prior antibiotic treatment does not reduce culture positivity and that empirical antibiotic therapy in culture-negative cases does not increase the risk of amputation or recurrence in…

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Negative / Null Result ReportOpen accessMedicine

Effects of the micronutrient Sanopal® (5-hydroxymethyl-2-furfural and α-ketoglutaric acid) on oxygen affinity of hemoglobin, oxygen saturation and exercise responses at altitude.

Woyke S, Troppmair T, Mair N et al. · 2026 · Journal of the International Society of Sports Nutrition

Background With increasing altitude, the partial pressure of oxygen and oxygen saturation (SpO 2 ) decrease, reducing physical performance. This study investigates whether the nutritional supplement Sanopal® (5-hydroxymethyl-2-furfural and…

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Negative / Null Result ReportMedicine

Evaluation of the clinical reasoning of GPT-4o, a multimodal generative artificial intelligence model, in 18 public gastroenterology case studies.

García-Rudolph A, Hernández-Pena E, Del Cacho N et al. · 2026 · Revista espanola de enfermedades digestivas

Introduction and aim although generative language models have been extensively studied in the field of digestive diseases, further progress requires addressing underexplored aspects such as linguistic bias, the evaluation of clinical…

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Negative / Null Result ReportOpen accessMedicine

Effect of Tranexamic Acid on Inpatient Admission and Revision Rates in Primary Rhinoplasty: A Propensity Score-Matched Analysis.

Mehdizadeh M, Smith JE, Gill J et al. · 2026 · Plastic and reconstructive surgery. Global open

Background Tranexamic acid (TXA) is commonly used to reduce intraoperative bleeding and complications across surgical specialties. In rhinoplasty, prior studies indicate that TXA may reduce postoperative edema and ecchymosis, but its…

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Negative / Null Result ReportMedicine

Beef quality and expression of genes involved in lipid metabolism in the muscle of Nellore and Nellore × Angus steers fed whole shelled corn diets.

Teixeira PD, Casagrande DR, Rodrigues AC et al. · 2026 · Meat science

Sixteen Nellore and Sixteen Nellore × Angus steers with an initial body weight of 353 kg ±25.3 kg were randomly assigned into 2 feeding groups: whole shelled corn without forage (WSC) or WSC with sugarcane bagasse (WSCB), to evaluate…

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