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Browse the failure-mode index

20,217 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Predictive value of thromboelastography with platelet mapping on hematoma expansion in spontaneous intracerebral hemorrhage.

Sammani N, Radosevich JJ, Martinez S et al. · 2026 · Journal of thrombosis and thrombolysis

Spontaneous intracerebral hemorrhage (ICH) accounts for about 10% of strokes in the United States and is linked to high mortality and morbidity. Hematoma expansion independently predicts poor outcomes. Thromboelastography with platelet…

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Negative / Null Result ReportMedicine

Broad skill generalization with an extra robotic body part.

Molina-Sanchez M, Dowdall L, Dominijanni G et al. · 2026 · Current biology : CB

Our ability to transfer motor skills across tools and contexts is central to how we adapt to an increasingly technological world. From smartphones to wearable robotics, modern technologies demand flexible motor control that generalizes…

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Negative / Null Result ReportMedicine

Radiopaque markers in children with functional constipation: Potential role in diagnosis, therapy, and outcomes.

Gomez-Suarez R, Lin E, Gershon E et al. · 2026 · Journal of pediatric gastroenterology and nutrition

Objectives To evaluate the clinical utility of the simplified colon transit protocol of radiopaque markers (SROM) in pediatric functional constipation (FC). Methods Retrospective study of children meeting Rome IV criteria for FC undergoing…

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Negative / Null Result ReportMedicine

Resting-state functional connectivity of the default mode network as a predictor for escitalopram response in adolescents with depression.

Jang M, Lee KH, Shin J et al. · 2026 · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Adolescent depression differs from adult depression in neurobiology and treatment response. Although resting-state functional connectivity (rsFC) of the default mode network (DMN) has been linked to treatment response in adults, its value…

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Negative / Null Result ReportOpen accessMedicine

Predicting Positive Affect in Infancy.

Grossmann T, Miller H, Allison O · 2026 · Developmental science

Positive affect (PA) is integral to health and development, yet its early origins remain largely unexplored. In this pre-registered study (N = 78), we investigated whether infant-specific biological and social-behavioral factors predict PA…

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Negative / Null Result ReportMedicine

Comparative Validation of Scoring Systems in Acute Traumatic Central Cord Syndrome: Acute Traumatic Central Cord Syndrome Score, Central Cord Score, and Subaxial Cervical AO Spine Injury Score for Surgical Decision Making, Recovery, and Timing of Surgery.

Kumar AA, Lim HL, Saffari SE et al. · 2025 · Journal of neurotrauma

Acute traumatic central cord syndrome (ATCCS) is the most common form of incomplete spinal cord injury. Treatment recommendations for ATCCS patients are largely from North America, and their applicability to Asian populations remains…

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Negative / Null Result ReportMedicine

Longitudinal Bidirectional Associations Between Early Adolescents' Externalizing and Posttraumatic Stress Symptoms and Substance Use Patterns.

Dunn CB, Farrell AD · 2026 · Research on child and adolescent psychopathology

Prior research has identified externalizing and internalizing pathways to adolescent-onset substance use, but few studies have considered how psychopathology is associated with the development of polysubstance use during early adolescence.…

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Negative / Null Result ReportMedicine

Parental Psychological Distress and Perceived Child Externalizing Behaviors: Examining Mediators and Bidirectional Effects.

Anderson AJ, Rodriguez CM, Henson JM · 2026 · Child psychiatry and human development

Parental psychological distress is a commonly examined risk factor for the emergence of child problem behaviors, but the factors that contribute to that relationship-such as limited parental resources like greater social support and coping…

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Negative / Null Result Report

Class Composition Effects in Achievement and Interest and the Role of the Learning Environment Revisited: A Conceptual Replication and Extension of Lavrijsen et al. (2022)

Kopatz M, Wagner W, Neuendorf C et al. · 2026 · Preprint

Class composition is a key contextual factor in students’ academic development. Prior research has mainly focused on class mean achievement, yet less is known about other composition characteristics, possible differences for students with…

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Negative / Null Result ReportMedicine

Ethnic-racial socialization and sociopolitical development among emerging adult college students of color.

Berkley S, Hoyt LT, Zeiders KH et al. · 2026 · Journal of research on adolescence : the official journal of the Society for Research on Adolescence

This study used multilevel growth modeling to examine associations between ethnic-racial socialization (ERS) and sociopolitical development among undergraduates of color (N = 125) attending predominantly White institutions during the 2016…

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Negative / Null Result ReportMedicine

Performance validity tests in a large racially and linguistically diverse pediatric and young adult clinical sample: Investigations of the TOMM, MVP, and MSVT.

MacAllister WS, Désiré N, Brooks BL · 2026 · The Clinical neuropsychologist

Objective There is strong support for the use of performance validity tests (PVTs) in all neuropsychological evaluations, however, research examining racial, ethnic, and linguistic differences in failure rates remains scarce, particularly…

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