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Browse the failure-mode index

19,830 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

The internal fit and fracture resistance of stainless-steel crowns and porcelain fused to metal crowns in intact and severely damaged permanent molars: an in vitro study.

Moosavi, Khorakian, Sedaghati et al. · 2026 · BMC oral health

Severe caries in mixed dentition frequently affects mandibular first permanent molars, often necessitating full-coverage restorations. Stainless steel crowns (SSCs) and porcelain-fused-to-metal (PFM) crowns are among the most commonly used…

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Negative / Null Result ReportMedicine

1-year patient-reported outcomes in patients with a documented GLP-1 agonist prescription history prior to total hip arthroplasty: a retrospective cohort study.

Benyamini, Khan, Elmenawi et al. · 2026 · Hip international : the journal of clinical and experimental research on hip pathology and therapy

Glucagon-like peptide-1 (GLP-1) receptor agonists are increasingly utilised for metabolic optimisation in surgical patients. Their effect on postoperative patient-reported outcomes (PROMs) and satisfaction following primary total hip…

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Negative / Null Result ReportMedicine

A descriptive, retrospective analysis of the quality of spontaneous adverse event reporting to the Côte d'Ivoire Pharmaceutical and Regulatory Authority and its impact on the causality assessment.

Kamagaté, Jusot, Mory et al. · 2026 · Therapeutic advances in drug safety

In Côte d'Ivoire, pharmacovigilance is not a routine activity in most healthcare facilities and many healthcare professionals have limited knowledge of pharmacovigilance methods. This study aimed to evaluate the quality of adverse…

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Negative / Null Result ReportMedicine

Clinical Performance of Bulk-Fill Versus Incremental Composite Placement Approaches in Vital Posterior Teeth: A 24 Months Randomized Controlled Trial.

Mohammed, Naser, Abozaid · 2026 · Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]

Composite resin placement technique may influence marginal integrity, polymerization stress distribution, and long-term clinical performance of posterior restorations. This randomized controlled clinical trial evaluated the 24-month…

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Negative / Null Result ReportMedicine

Impact of different domperidone dosages on reflux esophagitis treated with esomeprazole: a randomized controlled trial.

Niu, Bao, Zhao · 2026 · Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

This study aimed to systematically evaluate the efficacy and safety of different doses of domperidone (DOM) combined with esomeprazole (ESM) in the treatment of reflux esophagitis, providing a basis for precise clinical medication. This…

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Negative / Null Result ReportMedicine

Effect of pelvic floor muscle training with or without dynamic neuromuscular stabilization-based breathing on menstrual pain and symptoms of primary dysmenorrhea: a randomized controlled trial.

Yakıt Yeşilyurt, Birinci Olgun, Dağ et al. · 2026 · BMC women's health

Breathing exercises may modulate dysmenorrhea by enhancing relaxation and eliciting analgesic effects. This study investigated the effects of Pelvic Floor Muscle Training (PFMT) with or without Dynamic Neuromuscular Stabilization…

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Negative / Null Result ReportMedicine

Effect of driving pressure-guided individualized PEEP in children undergoing right lateral thoracotomy cardiac surgery with cardiopulmonary bypass on postoperative atelectasis and oxygenation: a randomized controlled trial.

Chen, Song, Zang et al. · 2026 · BMC anesthesiology

Right lateral thoracotomy cardiac surgery induces postoperative atelectasis due to cardiopulmonary bypass (CPB), patient positioning, and mechanical ventilation. Fixed positive end-expiratory pressure (PEEP) may fail to meet pediatric…

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Negative / Null Result ReportMedicine

Choroidal vascularity index in schizophrenia and bipolar disorder.

Yıldız, Çalış, Dokuz et al. · 2026 · Psychiatry research

This study examined differences in choroidal structural parameters, including the choroidal vascularity index, among patients with schizophrenia, bipolar disorder, and healthy controls. This cross-sectional study included 40 patients with…

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Negative / Null Result ReportMedicine

Evaluation of MRCP Findings in Distinguishing Benign from Malignant Causes of Isolated Main Pancreatic Duct Dilation.

Çınar, Uysal, Gürbüz et al. · 2026 · RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin

This study aimed to investigate morphological features on magnetic resonance cholangiopancreatography (MRCP) that may help distinguish benign from malignant causes of isolated main pancreatic duct (MPD) dilation detected without a visible…

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Negative / Null Result ReportMedicine

Synthesis and Biological Evaluation of a PET Probe: 4-Borono-2-[ 18 F]fluoro-l-phenylalanine ([ 18 F]FBPA) via an Iodonium Ylide Method for BNCT.

Li, Hu, Sun et al. · 2026 · The Journal of organic chemistry

Boron neutron capture therapy (BNCT) is a promising radiotherapeutic strategy for cancer treatment that selectively eradicates tumor cells while minimizing damage to surrounding healthy cells. 4-Borono-2-[ 18 F]fluoro-l-phenylalanine ([ 18…

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Negative / Null Result ReportMedicine

Impact of SARS-CoV-2 infection history on the clinical features and outcomes of patients with recurrent pulmonary tuberculosis: a retrospective case-control study.

Tang, Mi, Xue et al. · 2026 · Annals of medicine

The impact of prior SARS-CoV-2 infection on the clinical course of recurrent pulmonary tuberculosis (TB) remains poorly defined. This study aimed to compare clinical features, radiographic evolution, and outcomes in recurrent TB patients…

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Negative / Null Result ReportMedicine

Association Between Temporomandibular Joint Morphology and Mandibular Growth in Adolescents With Facial Asymmetry: An Magnetic Resonance Imaging and Cone-Beam Computed Tomography Study.

Wang, Guo · 2026 · The Journal of craniofacial surgery

To investigate the growth and developmental characteristics of the temporomandibular joint (TMJ) in adolescents with facial asymmetry and its relationship with mandibular morphological changes. A total of 20 patients aged 8 to 20 years…

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Negative / Null Result ReportMedicine

Choledochoduodenostomy versus transpapillary stent by endoscopic retrograde cholangiopancreatography for preoperative biliary drainage before pancreatoduodenectomy: a French multicenter retrospective cohort study.

Belfil, Diai, Gonzalez et al. · 2026 · Surgical endoscopy

 Few studies have compared the different types of endoscopic biliary drainage, particularly endoscopic retrograde cholangiopancreatography (ERCP) versus Endoscopic ultrasound guided-Choledochoduodenostomy (EUS-CD), for jaundice caused…

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