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Browse the failure-mode index

19,823 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Design and optimization of an automatic deep learning-based cerebral reperfusion scoring (TICI) using thrombus localization.

Folcher A, Piters J, Wallach D et al. · 2025 · Journal of neuroradiology = Journal de neuroradiologie

Background The Thrombolysis in Cerebral Infarction (TICI) scale is widely used to assess angiographic outcomes of mechanical thrombectomy despite significant variability. Our objective was to create and optimize an artificial intelligence…

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Negative / Null Result ReportMedicine

A single session of whole-body vibration did not affect cardiovascular autonomic recovery after a high intensity exercise in horses

Sales NAA, Carvalho JRG, Littiere TO et al. · 2025 · Journal of equine veterinary science

Whole-body vibration (WBV) has the potential to enhance post-exercise recovery in humans. Heart rate variability (HRV), a well-established biomarker of cardiac autonomic regulation (CAR), provides insight into autonomic reactivity during…

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Negative / Null Result ReportOpen accessMedicine

Trained immunity agonists given to neonatal mice fail to protect against leptospiral infection in adulthood and may cause adverse effects.

Fernandez M, Vernel-Pauillac F, Pezier T et al. · 2026 · Innate immunity

Background and ObjectivesTrained immunity (TI) refers to a non-specific, long-lasting protective immune response that occurs following initial stimulation of the immune system and thought to be largely mediated by functional reprogramming…

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Negative / Null Result ReportMedicine

The Effect of Surgeon Vocal Pitch and Gender on Patient Satisfaction.

Nuyen BA, Kruglik CP, Wang A et al. · 2026 · Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

Objective Patient satisfaction scores, especially the "likelihood to recommend" (LTR) a provider, are becoming increasingly important as measures of surgical quality. In this study, we examined the influence of a surgeon's vocal pitch and…

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Negative / Null Result Report

Pilot Testing a Narrative Psychoeducational Video to Reduce Stigma and Improve Mental Health Literacy and Help-Seeking Among Latinx Adults: Examining Gender Differences and Contextual Insights

Saravia DH, Silvan YA, Martinez JI · 2025 · Preprint

Abstract Despite similar rates of mental illness, non-Latinx Whites received care at higher rates compared to Latinxs (NIMH, 2024). Latinx adults report lower mental health literacy (MHL) and higher stigma compared to NLW, which can…

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Negative / Null Result ReportMedicine

The combination of lomustine and corticosteroids is a valid chemotherapeutic option in cats with presumptive central nervous system lymphoma.

Pauciulo C, Corda A, Tartari I et al. · 2026 · Journal of the American Veterinary Medical Association

Objective To describe the clinical outcomes of 10 cats diagnosed with CNS lymphoma treated with lomustine and corticosteroids. Animals Clinical records of privately owned cats diagnosed with CNS lymphoma and presented to a neurological…

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Negative / Null Result ReportMedicine

Hydroxyl-radical process for reducing Salmonella and Campylobacter jejuni on inoculated and naturally contaminated raw poultry parts with no change in quality metrics

Camacho-Martinez SV, Zai B, Hasani M et al. · 2025 · LWT.

The study aimed to optimize the performance of a gas phase hydroxyl radical process to inactivate Salmonella and Campylobacter jejuni associated with raw poultry meat. Chicken parts were inoculated with Salmonella or C. jejuni before…

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Negative / Null Result ReportMedicine

The Effect of Postexposure Sleep Deprivation on Anxiety-Related Behaviours and Hippocampal Neuropathological Changes in a Rat Model of Posttraumatic Stress Disorder.

Karabulut S, Topcu H, Er SN et al. · 2025 · International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience

Sleep problems are a hallmark of posttraumatic stress disorder (PTSD). Although the critical role of sleep for memory consolidation is well known, there is no consensus on the effect of sleep interruption or increased sleep duration…

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Negative / Null Result ReportMedicine

Cognitive Function Among Heart Transplant Recipients Before and After Intravenous Iron Supplement for Iron Deficiency: Results From a Randomized, Placebo-Controlled, Double-Blind Treatment Trial.

Bürker BS, Brautaset Englund KV, Myrdal Østby C et al. · 2025 · Clinical transplantation

Background Cognitive dysfunction after successful heart transplantation (HTx) is not uncommon. Lower hemoglobin levels have previously been associated with cognitive dysfunction in heart transplant recipients (HTx recipients). In a…

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Negative / Null Result ReportMedicine

Randomized Cross-Over Study to Examine Associations Between Dialyzer Clotting, Uremic Toxin Removal, and Hemocompatibility During Post-Dilution Hemodiafiltration With Reduced Anticoagulation.

Eloot S, Erlenkötter A, Zawada AM et al. · 2026 · Artificial organs

To date, it remains unclear to what extent dialyzer performance is affected by clotting, and which hemocompatibility parameters can reliably predict this phenomenon. This study investigated the relationship between dialyzer clotting,…

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Negative / Null Result ReportMedicine

Waggle-dance-recruited honeybees expect landscape structures.

Wang Z, Mach J, Chen X et al. · 2025 · Current biology : CB

Honeybee foragers explore the environment before they start foraging, following dances, or performing dances. Foragers are therefore familiar with the landscape surrounding the hive during their foraging career. Here, we ask whether…

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Negative / Null Result ReportMedicine

Comparison of a novel culture-based selection for dry cow therapy with somatic cell count-based selection: comparing detection rates for major pathogens and subsequent udder health outcomes.

Cuttance E, Nortje R, Laven R et al. · 2025 · The Journal of dairy research

This study compared a culture-based protocol in which only cows identified as having intramammary infections due to major pathogens (major IMI) were treated with dry cow antibiotics (DCAT) compared with the current New Zealand somatic cell…

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Negative / Null Result ReportMedicine

Ruminal degradation kinetics of mombasa and elephant grass silages as affected by fibrolyitc enzymes and regrowth ages.

de Lima Cruz GF, Pereira OG, Alves WS et al. · 2025 · Tropical animal health and production

Tropical grasses are widely used for silage, but their high fiber content and variable quality often limit ruminal degradation and animal performance. Strategies such as optimizing regrowth age (RA) and applying fibrolytic enzymes may help…

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