e-ISSN: Pending

Browse the failure-mode index

19,823 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Perinatal outcomes in normotensive versus hypertensive HELLP syndrome.

Anteby M, Wertheimer KO, Dominsky O et al. · 2026 · International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

Objective To compare maternal and neonatal outcomes between women with hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome with and without associated hypertension. Methods This was a retrospective cohort study at a…

View details →
Negative / Null Result ReportMedicine

Feasibility of a Noninvasive Core Temperature Sensor and the Effects of Combined Cooling on Thermal Strain and Performance in Beach Volleyball.

Hu X, Murakami G, Hasegawa H · 2026 · International journal of sports physiology and performance

Purpose This study evaluated the practical feasibility of the CORE sensor for noninvasive tracking of changes in estimated core body temperature (Est-Tcore) during simulated beach volleyball match-play in the heat and examined the effects…

View details →
Negative / Null Result ReportMedicine

Randomized controlled trial investigating the efficacy of oral azithromycin in preventing perinatal infections in pregnant women undergoing labor induction.

Cao H, Zhou Y, Gu N et al. · 2026 · International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

Objectives This study evaluates oral azithromycin's effectiveness in reducing intrapartum and puerperal infection rates in term pregnant women undergoing labor induction to guide antibiotic prophylaxis. Methods This single-center…

View details →
Negative / Null Result ReportMedicine

Utility of Very High Output Pace-Capture Testing for Posterior Wall Isolation in Patients With Persistent Atrial Fibrillation.

Hsia B, Liebman J, Garber L et al. · 2026 · Journal of cardiovascular electrophysiology

Background Pulmonary vein isolation (PVI) and posterior wall isolation (PWI) are frequently used in the treatment of persistent atrial fibrillation (AF). Minimal data support adjunct PWI, possibly due to lack of durability via epicardial…

View details →
Negative / Null Result ReportMedicine

Size and Macroscopic Type of Type B2 Vessel Areas in JES Classification for Predicting Invasion Depth: A Multicenter Prospective Study.

Yoshida M, Urabe Y, Kadota T et al. · 2026 · Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society

Objectives To investigate whether considering the B2 vessel area (B2VA) size and macroscopic type improves diagnostic performance. Methods In total, 136 esophageal squamous cell carcinoma (ESCCs) with B2 but not B3 vessels were…

View details →
Negative / Null Result ReportMedicine

Effects of (poly)phenol-rich cranberry on mental health in university students: The CRANMOOD randomised controlled trial.

Kamarunzaman NNZ, Le Sayec M, Li Y et al. · 2026 · Clinical nutrition (Edinburgh, Scotland)

Background and aims Increasing evidence indicate that (poly)phenol-rich foods can have beneficial effects on human brain function. This study investigated whether daily (poly)phenol-rich cranberry supplementation for 12 weeks influences…

View details →
Negative / Null Result ReportMedicine

Prenatal representations of women with minor depressive symptoms: a randomised controlled trial of an interactive ultrasound intervention.

Lindstedt J, Ekholm E, Pulliainen H et al. · 2026 · Journal of reproductive and infant psychology

Background Maternal depressive symptoms are common during pregnancy and may negatively impact the mother-infant relationship, particularly the development of maternal prenatal representations. This study used a randomised controlled trial…

View details →
Negative / Null Result ReportMedicine

Nivolumab plus chemoradiotherapy followed by nivolumab with or without ipilimumab for untreated locally advanced stage III NSCLC: a randomized phase 3 trial.

Peters S, Tan DSW, Gerber DE et al. · 2026 · Nature cancer

Over 50% of persons with unresectable stage III non-small cell lung cancer (NSCLC) treated with standard-of-care concurrent chemoradiotherapy (CCRT) and durvalumab consolidation progress or die within 18 months. Here adults with untreated,…

View details →
Negative / Null Result ReportMedicine

Predicting parents' HPV vaccination intentions and behaviors across countries and time.

Schulz JV, Doerflinger JT, Behm C et al. · 2026 · Health psychology : official journal of the Division of Health Psychology, American Psychological Association

Objective This study compares three models of parental human papillomavirus (HPV) vaccination intentions across United States, United Kingdom, and Germany: A model based on the theory of planned behavior (TPB), a model incorporating…

View details →
Negative / Null Result ReportOpen accessMedicine

Combined Detection of Preoperative Serum Calcitonin and Carcinoembryonic Antigen in Medullary Thyroid Carcinoma: A Retrospective Multicenter Cohort Study.

Yang Y, He Y, Lin B et al. · 2026 · Health care science

Background The aim of this study was to investigate the clinical value of combined detection of preoperative serum calcitonin (Ctn) and carcinoembryonic antigen (CEA) for diagnosing medullary thyroid carcinoma (MTC), as well as predicting…

View details →
Negative / Null Result ReportMedicine

A novel approach to the clinical assessment of juvenile fibromyalgia syndrome: the Juvenile Fibromyalgia Multidimensional Assessment Report.

Drago E, Lavarello C, Alongi A et al. · 2026 · Clinical and experimental rheumatology

Objectives Development and psychometric evaluation of a disease-specific, paediatric-targeted multidimensional questionnaire for the assessment of juvenile fibromyalgia syndrome (JFS) in routine clinical practice. Methods The Juvenile…

View details →
Negative / Null Result ReportMedicine

The effect of mitomycin-C on 3 snip punctoplasty.

Dertsiz Kozan B, Utlu B · 2026 · International ophthalmology

Purpose To investigate the effects of Mitomycin-C (MMC) use and duration of application on surgical outcomes in patients who underwent 3 snip punctoplasty for epiphora. Material and methods Demographic characteristics, follow-up period,…

View details →
Negative / Null Result ReportMedicine

Patient-Level Modeling of Ménière's Disease vs. Vestibular Migraine: Performance of Speech Discrimination and Caloric-vHIT Dissociation.

Pérez-Fernández N, Arbizu L · 2026 · Journal of clinical medicine

Background : Differentiating Ménière's disease (MD) from vestibular migraine (VM) remains difficult because current diagnostic frameworks are predominantly clinical and incorporate pure-tone thresholds, risking incorporation bias. We asked…

View details →
Negative / Null Result ReportMedicine

Effectiveness and safety of treatment for heterozygous familial hypercholesterolaemia and multifactorial dyslipidaemia in children: an overview of systematic reviews.

Le Thi TG, Geist M, Novosad Y et al. · 2026 · European journal of preventive cardiology

Aims This overview of systematic reviews (SRs) summarizes evidence on effectiveness and safety of treatment for paediatric heterozygous familial hypercholesterolaemia (heFH) and multifactorial dyslipidaemia (MFD). Methods and results…

View details →
Negative / Null Result ReportMedicine

Clinical and microbiological characteristics of multidrug-resistant acute bacterial endophthalmitis after cataract surgery. Endophthalmitis Management Study Report # 8.

Das T, Belenje A, Joseph J et al. · 2026 · Retina (Philadelphia, Pa.)

Purpose Report the clinico-microbiological characteristics of multidrug-resistant acute postcataract bacterial endophthalmitis. Methods Consecutive 32 cases from a prospective multicenter study in India were analyzed for the clinical…

View details →