20,217 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Wang J, He B, Kuerban G et al. · 2026 · Pakistan journal of pharmaceutical sciences
Background Evidence from experimental and clinical studies suggests that anesthetic drugs may modulate tumor biology by influencing immune regulation, inflammation and intracellular calcium signaling. However, the extent to which…
View details →Wang Y, Qu J, Wang T et al. · 2026 · Blood purification
The relationship between baseline serum creatinine (SCr) levels at the initiation of continuous renal replacement therapy (CRRT) and in-hospital mortality remains unclear. This study aimed to investigate this relationship in critically ill…
View details →Sharma M, Kaur N · 2026 · Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes
The reproductive toxicity of nitrate in juvenile and adult female rats, and its amelioration with ascorbic acid, curcumin or their combination, was studied. Rats were classified into five groups: control, nitrate, nitrate + ascorbic acid,…
View details →Egorova K, Maaniitty T, Kärpijoki H et al. · 2026 · Preprint
Peripheral physiological processes contribute to emotions; however, the extent of the influence of internal signals on subjective emotional experiences remains a subject of debate. Methods Here we investigated the bodily sensations induced…
View details →Puga T, Haechten T, Cush C et al. · 2025 · Orthopaedic journal of sports medicine
Background Kickoffs in the National Football League (NFL) are historically one of the most dangerous plays during an NFL game, with high levels of injuries. In 2024, the NFL introduced new rules aimed at reducing injuries during kickoffs,…
View details →Javaheri J, Asgari M, Mohaghegh P et al. · 2026 · Preprint
Abstract Background: Routine monitoring, identification, early diagnosis and screening of diseases caused by environmental and industrial pollutants by all physicians who will practice in large and polluted cities or areas affected, must…
View details →Sliman H, Sliman RKA, Aker A et al. · 2026 · Preprint
Abstract Background: Emotional stress in conflict zones may impact cardiovascular health, particularly acute coronary syndrome incidence. This retrospective study assesses the Israel–Hamas conflict's impact on ST-elevation myocardial…
View details →Zander C, Rau A, Lützen N et al. · 2026 · Fluids and barriers of the CNS
BACKGROUND: CSF loss in spontaneous intracranial hypotension (SIH) has been related to alterations in glymphatic flow, which is poorly understood in this disease. Advanced multi-shell diffusion-weighted MRI (dMRI) enables quantification of…
View details →Berube M, Bortman JM, Law AC et al. · 2026 · Hip international : the journal of clinical and experimental research on hip pathology and therapy
Background The optimal threshold to blood transfusion in patients after hip fracture surgery is unclear. This study leveraged regression discontinuity to quantify blood transfusion practices across haemoglobin thresholds of 7.0, 8.0, and…
View details →Li Y, Wang D, Liu B et al. · 2026 · Preprint
Abstract Background Pulsed field ablation (PFA) is a novel non-thermal technology for atrial fibrillation (AF) ablation, but its immediate systemic effects on electrolytes remain poorly characterized. Methods We prospectively enrolled 161…
View details →Darch W, Soliman J, Higgins NC et al. · 2026 · Scientific reports
Vascular endothelial cells (VECs) play a critical role in tissue and organ homeostasis, wound healing, and immune function. VECs are commonly utilized for in vitro cell culture and in vivo tissue engineering applications which experience…
View details →Almekaty K, Alhefnawy M, Ismael A et al. · 2026 · Urology
Objective To prospectively assess the clinical outcomes and safety of microsurgical denervation of the penis (MSDP) for treatment of lifelong premature ejaculation (LPE); and to examine the impact of transitioning from partial to more…
View details →Salem AS, Albelasy NF, El-Bialy AA · 2026 · The Angle orthodontist
Objectives To compare the effectiveness of clear aligner (CA) vs removable inclined plane (RP) in improving the dentofacial changes and oral health-related quality of life (OHRQoL) in children with anterior crossbite in the mixed…
View details →Erdem Altınyürek E, Öztürk VÖ · 2026 · BMC oral health
Background Gastritis is characterized by alterations in the gastric microbiota. This dysbiosis in the stomach may affect immune system regulation as well as influence the oral microbiota. Periodontal disease results from dysbiosis of…
View details →Mamun AA · 2026 · 3 Biotech
Drought significantly alters soil microbial activity and carbon cycling, yet its effects across contrasting land-use systems remain insufficiently understood. This study investigated drought-induced changes in microbial communities and…
View details →Tuncsoy M, Tuncsoy B · 2026 · Bulletin of environmental contamination and toxicology
Aluminum (Al) is a widely occurring element in nature and is the most abundant element in the earth's crust after oxygen and silicon. In this study, metal accumulation levels in the gills, liver and muscle tissues and liver SOD, CAT and…
View details →Nersesyan A, Kundi M, Muradyan R et al. · 2026 · Mutagenesis
We investigated the impact of cigarette smoking, daily exposure to tar and nicotine, and the duration of smoking on genetic instability (chromosomal damage-micronuclei, MN, nuclear buds-gene amplification) as well as on disturbances in…
View details →Bakir M, Sağmak S · 2026 · BMC oral health
Background This study aimed to evaluate the effects of different modeling resins on the surface roughness, surface gloss, and color stability of a nanohybrid resin composite. Methods Forty disk-shaped specimens (10 mm diameter × 2 mm…
View details →Kaplan S, de Nascimento J, Contini A · 2026 · Drug safety
Background and objectives Concerns about modafinil and armodafinil use in pregnancy emerged from animal reproductive toxicity and limited human data, including a US registry suggesting increased risk of major congenital malformations…
View details →Saud MA, Khamees Abed S, Shahooth MA et al. · 2026 · Preprint
Background: While ivermectin is a common antiparasitic drug used in veterinary medicine, the effects of repeated administration at therapeutic doses have not been well studied. Of particular interest is the impact of ivermectin on…
View details →Moreira-Vera D, Solórzano MLP, Marín-Pérez AL · 2026 · Preprint
Abstract Introduction: Ethical decision-making is a core competency in medical training. However, evidence regarding moral reasoning and ethical sensitivity among medical students in Latin America remains limited, particularly in settings…
View details →Hamsika V, Batra P, Bhaskar V et al. · 2026 · Pediatric emergency care
Objective To compare IVC/Ao ratio, IVC collapsibility/distensibility indices before and after the administration of fluid bolus therapy in children with non-hemorrhagic shock using point of care ultrasound, and to correlate the changes in…
View details →Ali ET, Findlay BL · 2026 · Preprint
Sustainable agriculture has driven increased exploration of microbial inoculants as a promising strategy to boost plant growth for higher yield and enhance secondary metabolism to increase crop nutritional value. However, their influence…
View details →Wang W, Chen Z, Li M et al. · 2026 · Preprint
Fundus fluorescein angiography (FFA) is the gold standard for assessing diabetic retinopathy (DR) severity, but whether different contrast diffusion times affect staging remains unclear. Following two clinical DR staging criteria, we…
View details →Zein MMA, Win KT, Alananzeh I · 2026 · Healthcare informatics research
Objectives This study aims to explore the key factors that enhance engagement in Facebook health support groups among Australian culturally and linguistically diverse (CALD) communities. Methods A cross-sectional online survey was…
View details →Marani N, di Gennaro D, Garotti R et al. · 2026 · Frontiers in psychiatry
Introduction Sensory processing abnormalities represent a high-impact clinical feature in individuals with Autism Spectrum Disorder (ASD). Sensory alterations can be classified by modality and behavioral responses to stimuli. The…
View details →Ansari D, Bethel JA, Greeneway GP et al. · 2026 · Operative neurosurgery (Hagerstown, Md.)
Background and objectives Lateral interbody fusion represents a minimally-invasive approach to achieve indirect decompression via disc height restoration and alignment correction in patients with degenerative lumbar spondylolisthesis. If…
View details →White RL, Read QD, Valles SM · 2026 · Journal of invertebrate pathology
Solenopsis invicta virus 3 (SINV3) is a biological control agent against the red imported fire ant, S. invicta. We attempted to improve the virus' effectiveness with organosilicone adjuvants hydroxy trisiloxane [hydroxyTSX] and methoxy…
View details →Rasmussen PL, Rinnan Å, Nielsen SB et al. · 2026 · Food Hydrocolloids.
The utilization of bovine casein for creating casein micelles with properties resembling those in human milk presents an opportunity to bridge the nutritional gap between human milk and infant formula. However, the processing of these…
View details →Williams AJ, Pum JM, Deyoung JK et al. · 2026 · The journal of hand surgery Asian-Pacific volume
Background: The purpose of this study was to compare Patient-Reported Outcomes Measurement Information System (PROMIS) Upper Extremity (UE) and PROMIS Pain Interference (PI) scores before and after carpal tunnel release (CTR) between…
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