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19,823 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Nature Connectedness and Work Engagement in the Relationship Between Emotional Exhaustion and Life Satisfaction Among Employees.

Jaime-Jorge S, García-Ael C, Azanza G et al. · 2026 · European journal of investigation in health, psychology and education

This paper analyses associations between psychological health at work and life satisfaction among employees. Specifically, it investigates the association between work stress and emotional exhaustion and explores whether connectedness to…

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Negative / Null Result ReportMedicine

Aqueous PFOS exposure decouples gaseous carbon loss from mineral-associated carbon retention in controlled wetland-interface mesocosms.

Lu B, Wang P, Hu J et al. · 2026 · Environmental pollution (Barking, Essex : 1987)

Wetland interfaces regulate greenhouse-gas exchange and carbon retention, yet contaminant exposure may disrupt the relationship between these two processes. Whether aqueous perfluorooctane sulfonate (PFOS), a persistent aquatic…

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Negative / Null Result ReportMedicine

Factors associated with achieving knee flexion around one hundred and twenty five degrees and numerical rating scale around one at one year after posterior cruciate-retaining total knee arthroplasty.

Shioiri H, Takahashi T, Matsumoto T · 2026 · International orthopaedics

Purpose To investigate factors associated with achieving both postoperative knee flexion range of motion (ROM) ≥ 125° and Numerical Rating Scale (NRS) pain score ≤ 1 at one year after posterior cruciate-retaining total knee arthroplasty…

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Negative / Null Result ReportMedicine

Risk factors for multidrug resistance and mortality in healthcare-associated neonatal gram-negative bloodstream infections.

Turgut H, Özdemir R, Memişoğlu F · 2026 · European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology

Purpose This study aimed to characterize pathogen distribution and antimicrobial resistance patterns of gram-negative bloodstream infections in a tertiary neonatal intensive care unit and to determine which factors were associated with…

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Negative / Null Result ReportMedicine

Risk factors and the effect of belimumab on flares during glucocorticoid tapering in systemic lupus erythematosus: A multicentre ANSWER-SLE cohort study.

Miyake H, Onishi A, Tsuji H et al. · 2026 · Modern rheumatology

To identify factors associated with flare after glucocorticoid (GC) reduction in systemic lupus erythematosus (SLE) and determine whether belimumab influences this risk. Using the ANSWER-SLE cohort, this retrospective multicentre study…

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Negative / Null Result ReportMedicine

Structural and load-dependent arterial stiffness are differentially associated with cognition or biomarkers of Alzheimer's disease and related dementias: The healthy brain study.

Deconne TM, Suerken CK, Lipford ME et al. · 2026 · Journal of Alzheimer's disease : JAD

BackgroundArterial stiffness is an emerging risk factor for Alzheimer's disease (AD) and related dementias (ADRD) and is assessed by measuring pulse wave velocity (PWV). Recent mathematical modeling has allowed for the delineation of…

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Negative / Null Result ReportMedicine

Transitioning to Adult Caregiving and Grandchild Care Are Associated With Mental and Physical Health Outcomes Among Middle-Aged and Older Adults: Longitudinal Evidence From South Africa, 2015-2022.

Pengpid S, Peltzer K, Hajek A · 2026 · Australasian journal on ageing

Objectives The aim of this study was to assess the longitudinal association between transitioning to adult caregiving, grandparent childcare and mental health outcomes (depressive symptoms, life satisfaction and cognitive functioning) and…

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Negative / Null Result ReportOpen accessMedicine

Chronic kidney disease screening and associated factors among people living with HIV on anti-retroviral therapy in Dar Es Salaam, Tanzania: Hospital-based cross-sectional study.

Theophil M, Lyimo AA, Ambikile JS · 2026 · PloS one

Background Chronic Kidney Disease (CKD) is a significant global health challenge, particularly among people living with HIV (PLHIV) on antiretroviral therapy (ART). The combined effects of HIV infection, long-term ART exposure, and other…

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Negative / Null Result ReportMedicine

Quantitative Systems Toxicology Model Predicts Obeticholic Acid-Associated Liver Injury in Metabolic Dysfunction-Associated Steatotic Liver Disease.

Mayo AK, Beaudoin JJ, Woodhead JL et al. · 2026 · Clinical pharmacology and therapeutics

Obeticholic acid (OCA), a synthetic analog of chenodeoxycholic acid, was approved in 2016 for the treatment of primary biliary cholangitis. Early clinical trials revealed elevated liver biomarkers in healthy subjects receiving…

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Negative / Null Result ReportOpen accessMedicine

Pulmonary Fibrosis and Pulmonary Function in Patients with Metastatic Testicular Cancer During and after Combination Chemotherapy: The BLEOTOX Study.

Frey L, Grunwald S, Ruckes C et al. · 2026 · European urology open science

Background and objective Metastatic testicular germ cell tumors (mTGCTs) are treated with combination chemotherapy (Cx) containing bleomycin (BEP [bleomycin, etoposide, and cisplatin]). Bleomycin-induced pulmonary toxicity (BPT) is a…

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Negative / Null Result ReportMedicine

Association between extubation timing and functional outcomes in patients with acute ischemic stroke after endovascular treatment.

Liang D, Tong Y, Li F et al. · 2026 · Cerebrovascular diseases (Basel, Switzerland)

Introduction General anesthesia (GA) with endotracheal intubation is standard during endovascular treatment (EVT) for acute ischemic stroke (AIS), but the optimal timing for post-procedural extubation remains unclear. Methods In this…

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Negative / Null Result ReportMedicine

Preoperative posterior pelvic tilt is associated with residual low back pain and inferior patient-reported outcomes after total hip arthroplasty.

Ito K, Fujii M, Oba Y et al. · 2026 · International orthopaedics

Purpose To determine changes in low back pain (LBP) after total hip arthroplasty (THA), identify preoperative factors associated with residual LBP and LBP improvement, and clarify the association between residual LBP and patient-reported…

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Negative / Null Result ReportMedicine

Water intake, switching between bites and sips, and drinking behavior are associated with food intake across meals varying in spiciness: A secondary analysis of two randomized crossover studies.

Cunningham PM, Hayes JE · 2026 · Appetite

Widespread nutrition advice instructs consumers to drink water with meals to increase fullness and reduce energy intake. However, recent data indicates greater water intake is associated with more food intake at a meal, not less. Switching…

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Negative / Null Result ReportMedicine

High daily fructose intake and late-evening fruit consumption are associated with ultrasonographically assessed hepatic steatosis in family medicine outpatients.

Ediz E, Küçükdağ HN, Özel MA · 2026 · Scientific reports

Although high fructose consumption is known to be associated with metabolic disorders, specific intake thresholds and consumption patterns related to hepatic steatosis have not been fully defined. This study aimed to quantify daily…

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Negative / Null Result ReportMedicine

Investigating patterns of long-term opioid usage in 11,771 trauma survivors with up to 6 years follow-up in Denmark.

Millarch AS, Schøning J, Hjulmand VG et al. · 2026 · The journal of trauma and acute care surgery

Background Opioids have a well-known capacity to induce long-term dependency with related increased morbidity and mortality. Usage patterns following traumatic injury are, however, not well studied. We investigated long-term opioid usage…

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Negative / Null Result ReportMedicine

Longitudinal analysis of 15-year health outcomes after combat-related lower limb amputation: A retrospective study.

Melcer T, Robinson MI, Jurick S et al. · 2026 · The journal of trauma and acute care surgery

Background Limited longitudinal research has been conducted on health outcomes during the first 15 years after combat-related lower limb amputation. Methods This retrospective analysis of Departments of Defense and Veterans Affairs health…

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Negative / Null Result ReportMedicine

Sub-Minimum Inhibitory Concentrations of Amoxicillin Modulate Biofilm Formation and the Expression of Biofilm-Associated Genes in <i>Enterococcus faecalis</i>.

Tegegne DT, Banaszkiewicz S, Bania J et al. · 2026 · Molecules (Basel, Switzerland)

Background: Enterococcus faecalis is one of the most frequent causes of catheter-associated urinary tract infections, largely due to its ability to form biofilms on indwelling urinary catheter surfaces, which enhance bacterial persistence…

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Negative / Null Result ReportOpen accessMedicine

Isolated Peripheral Nervous System Presentation in Ma/Ma2-Associated Autoimmunity.

Vilaseca A, Villagrán-García M, Farina A et al. · 2026 · Neurology(R) neuroimmunology & neuroinflammation

Objectives Ma/Ma2-associated neurologic autoimmunity is characterized by CNS involvement. However, isolated peripheral nervous system (PNS) presentations have been rarely reported. We aimed to describe the frequency and syndromes of…

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Negative / Null Result ReportOpen accessMedicine

An analysis of succinate dehydrogenase B in pleural mesothelioma.

Jennings CJ, Marciniak SJ, Pinton G et al. · 2026 · Discover oncology

Aim To investigate the expression of succinate dehydrogenase B and its potential as a therapeutic target in pleural mesothelioma (PM). Methods The expression of succinate dehydrogenase B was examined in cell lines using PCR. The expression…

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