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Browse the failure-mode index

19,820 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result Report

#4204 MULTIPARAMETRIC MAGNETIC RESONANCE IMAGING BIOMARKERS OUTPERFORM LAB BIOMARKERS FOR PREDICTING PROGRESSION OF DIABETIC KIDNEY DISEASE

Paul Hockings, Kianoush Makvandi, Johannes Hulthe et al. · 2023 · Nephrology Dialysis Transplantation

Abstract Background and Aims We recently showed that comprehensive non-contrast multiparametric Magnetic Resonance Imaging (mpMRI) allowed functional and structural assessment of diabetic kidney disease (DKD) and that an imaging endpoint,…

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Negative / Null Result Report

Abstract 191: Alcohol Consumption Before Injury Did Not Improve Neurological Outcomes In Patients With Severe Traumatic Brain Injury: A Nationwide, Retrospective Cohort Study

Tsuyoshi Nojima, Hiromichi Naito, Takashi Hongo et al. · 2022 · Circulation

Introduction: Traumatic brain injury (TBI) is a major global public health concern. Notably, alcohol may confer neuroprotective effects by inhibiting of N-methyl-D-aspartate receptors; however, the impact of alcohol exposure before injury…

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Negative / Null Result Report

An impedance threshold device did not improve carotid blood flow in a porcine model of prolonged cardiac arrest

Benedict Kjaergaard, Hans O. Holdgaard, Sigridur O. Magnusdottir et al. · 2020 · Journal of Translational Medicine

Abstract Background An impedance threshold device (ITD) was developed to increase venous return to the heart and therefore increase cardiac output and organ blood flow during cardiopulmonary rescue (CPR). Basic CPR aims to maintain…

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Negative / Null Result Report

Molecular Diagnostic Techniques Used to Confirm an Unusual Case of BAPoma

Aaron Atkinson, Konstantinos Linos, Shaofeng Yan et al. · 2017 · The FASEB Journal

Study Objective BAP1 (BRCA1‐associated protein 1) is a critical tumor suppressor that promotes genome stability and DNA damage response, in addition to other cellular processes. BAP1 maps to 3p21 and is a nuclear localized deubiquitinating…

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Negative / Null Result Report

Patient leaflets on respiratory tract infections did not improve shared decision making and antibiotic prescriptions in a low-prescriber setting

Andreas Plate, Stefania Di Gangi, Christian Garzoni et al. · 2024 · Scientific Reports

Abstract Patient information leaflets can reduce antibiotic prescription rates by improving knowledge and encouraging shared decision making (SDM) in patients with respiratory tract infections (RTI). The effect of these interventions in…

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Negative / Null Result Report

Optimization of Tempering Process Parameters of AISI 3140 Low Alloy Steel to Conserve Furnace Energy using Tukey’s Honestly Significant Difference Test

SK Lakshmana Moorthy, S Rajaram, PC Santhosh Kumar · 2020 · IOP Conference Series: Earth and Environmental Science

Abstract Quenching and Tempering of AISI 3140 alloy steel is a necessary heat treatment process to attain desired hardness and toughness. However the tempering process consumes remarkable amount of energy in furnace. One of the usual…

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Negative / Null Result Report

There is no significant difference in the treatment of aspiration pneumonia in dogs with ampicillin-sulbactam versus ampicillin-sulbactam and enrofloxacin

Cody I. Riffe, Justin A. Heinz, Carly A. Patterson et al. · 2025 · Journal of the American Veterinary Medical Association

Abstract Objective Describe outcomes for dogs with aspiration pneumonia (AP) initially treated with ampicillin-sulbactam (AS) alone (monotherapy [MT]), initially with AS and enrofloxacin (initial dual therapy [iDT]), or initially with AS…

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Negative / Null Result Report

Sildenafil does not have a significant effect on the portal vein velocity, cross-sectional area, and congestion index in the dog

Christopher R. Tollefson, Marc A. Seitz, Claudio C. Natalini et al. · 2022 · Frontiers in Veterinary Science

In veterinary medicine, sildenafil is most frequently used to treat pulmonary hypertension, but has also been investigated and used as a treatment for congenital megaesophagus and ischemic infarcts. With the increasing use, the effects of…

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Negative / Null Result Report

Statistical Analysis of the Number of Infections with Corona Virus in Some Arab Countries Using the Method of Least Significant Difference

Hadeel Alkutubi, Rania Abod, Omaima Jabber · 2022 · Journal of Kufa for Mathematics and Computer


 
 
 In this research, we applied actual data related to the number of infections with the Corona virus for some Arab countries for the month of February of the year 2022, where the method of least significant difference…

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Negative / Null Result Report

Screening check test to confirm the relative reactivity and applicability of 2,4-dinitrophenylhydrazine impregnated-filters for formaldehyde on other compounds

Naoko Inoue, Mitsutoshi Takaya · 2022 · Journal of Occupational Health

Abstract Objectives A simple check test method was designed to confirm whether a 2,4-dinitrophenylhydrazine (DNPH) filter for formaldehyde can be used to measure other compounds. Methods Sample mixtures containing the same concentrations…

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Negative / Null Result Report

Autopsy of a failed extension policy

Bradley “Peanut” McCoy · 2022 · The Physics Teacher

There is a challenge as an instructor to balance the tension between flexibility and accountability in assignment due dates. I have long used an extension policy in my classes out of a desire to give students some flexibility on due dates.…

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Negative / Null Result Report

Correlation Analysis of Bronchial Blocker Insertion Depth in Thoracic Surgery: A Prospective Observational Study

Yang Xiao null, Wei Kang null, Qibin Ke null et al. · 2025 · American Journal of Clinical and Experimental Medicine

Background: The insertion depth of the bronchial blocker demands precise positioning and bronchoscopic confirmation. This study aims to investigate the parameters that influence the insertion depth of bronchial blockers in thoracic…

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Negative / Null Result Report

Humans Outperform Machines at the Bilingual Shannon Game

Marjan Ghazvininejad, Kevin Knight · 2016 · Entropy

We provide an upper bound for the amount of information a human translator adds to an original text, i.e., how many bits of information we need to store a translation, given the original. We do this by creating a Bilingual Shannon Game…

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Negative / Null Result Report

VARK: Linking Teaching Strategies to Preferred Learning Styles

Michelle Van Der Wege, null null, null null et al. · 2020 · John Heinrichs Scholarly & Creative Activities Day

Background: Nursing education is constantly changing in order to meet the ever-changing needs of the nursing profession. Long gone are the days of lengthy lectures and rote memorization. In order to adequately meet the demands of the…

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Negative / Null Result Report

Whom did the karasuk people resemble?

A. G Kozintsev · 2023 · Etnograficheskoe obozrenie

To test Yuri Rychkov’s claim that the physical type of the Karasuk people was identical to that of the highlanders of Western Pamir, 24 male Karasuk cranial samples were subjected to a multivariate comparison with 59 samples representing…

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Negative / Null Result Report

Why did Endurance sink?

Jukka Tuhkuri · 2025 · Polar Record

Abstract Sir Ernest Shackleton’s ship, Endurance , was crushed by Antarctic sea ice and sank in November 1915. Since then, it has been widely considered that Endurance was the strongest polar ship of its time and was lost because ice tore…

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Negative / Null Result Report

Did Aristotle have a Doctrine of Existential Import?

Byeong-uk Yi · 2025 · Open Philosophy

Abstract Modern logicians hold that traditional logic makes a serious error by accepting the subalternation thesis , the thesis that universal affirmatives imply matching particular affirmatives. But some traditional logicians (e.g.,…

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Negative / Null Result Report

The Role of Entrepreneur Characteristics and Entrepreneur Motivation has a significant effect on SMEs' Business Performance During Digital Era

Heri Erlangga, Yanti Purwanti, Tita Setiawati et al. · 2021 · International Journal of Artificial Intelligence Research

The purpose of this study was to analyze the relationship between Entrepreneur Characteristics and Business Performance variables, the relationship between entrepreneurial motivation variables and MSME business performance. In this study…

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Negative / Null Result Report

Abstract P1-11-02: A comparison of models (physician, the Van Nuys prognostic index, the Memorial-Sloan-Kettering Cancer Center DCIS nomogram)to predict ipsilateral breast events in patients with ductal carcinoma in situ (DCIS) of the breast after breast-conserving surgery failed to replicate results of the oncotype DCIS recurrence score

C Leonard, R Lei, A Antell et al. · 2017 · Cancer Research

Abstract Purpose: To compare ipsilateral breast event (IBE) risks in patients with DCIS of the breast post-lumpectomy, as estimated by breast radiation oncologists, the Van Nuys Prognostic Index (VNPI) studies, the Memorial Sloan Kettering…

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Negative / Null Result Report

Persistent Nanophosphors: Poised to Outperform Bulk Counterparts?

Victor Castaing, Simon Delacroix, Thierry Gacoin et al. · 2026 · Advanced Optical Materials

Abstract The design of advanced materials often reveals how apparent imperfections, such as structural defects or impurities, can be transformed into functional advantages. In insulating oxide matrices, the controlled introduction of…

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