Negative / Null Result Report
Konstantinos Gkiouras, Maria-Eleftheria Choleva, Aikaterini Verrou et al. · 2022 · Nutrients
Positive (statistically significant) findings are easily produced in nutrition research when specific aspects of the research design and analysis are not accounted for. To address this issue, recently, a pledge was made to reform nutrition…
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Andrey Borisov, Alexey Bosov, Gregory Miller · 2022 · Mathematics
The paper presents an optimal control problem for the partially observable stochastic differential system driven by an external Markov jump process. The available controlled observations are indirect and corrupted by some Wiener noise. The…
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Riyam Mistry, Fadi Issa · 2022 · Frontiers in Surgery
Introduction Paediatric burns are a common clinical presentation. The long-term scar outcomes in paediatric burns patients are relatively unknown as most are discharged after 6 weeks follow up, apart from the small number that are followed…
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Oscar A. Chavez, Walter Renberg, Natalia Cernicchiaro · 2024 · American Journal of Veterinary Research
Abstract OBJECTIVE Effect of photobiomodulation therapy (PBMT) in patients with CCLR after TPLO surgery by measuring C-reactive protein (CRP), percentage weight bearing, lameness using a short form of a composite measure pain scale,…
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Shova Mishra, Peter DiGennaro · 2020 · Journal of Nematology
Abstract Root-knot nematodes (RKN; Meloidogyne spp.) are obligate plant parasites that require constant communication with their host to establish and maintain specialized feeding cells. The intimacy of this interaction likely requires…
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Kerry A. Rogers, Jennifer A. Woyach · 2024 · Hematology
Abstract Frontline therapy for chronic lymphocytic leukemia (CLL) has substantially advanced in the previous decade. While monotherapy with a Bruton's tyrosine kinase (BTK) inhibitor is an excellent option for many patients, combination…
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Matthew P. Steinberg, Rand Quinn, J. Cameron Anglum · 2020 · Journal of Education Finance
abstract: We estimate the impact of school finance reform on adequate and equitable district spending, school resources and student achievement in Pennsylvania. From the 2008-09 to the 2010-11 school years, amid the Great Recession,…
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Ann Armstrong · 2024 · Equality, Diversity and Inclusion: An International Journal
Purpose I examine if current diversity, equity and inclusion (DEI) initiatives can actually accomplish what they aim and claim to do. I argue that perforce they cannot, as they remain instruments of capitalist corporations and other…
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Vladimira Vroblova, Filip Vrbacky, Monika Hrudkova et al. · 2010 · European Journal of Haematology
Abstract Introduction: It is widely accepted that expression of ZAP‐70 in chronic lymphocytic leukemia (CLL) remains stable in time. However, data supporting this notion are surprisingly scarce. Therefore, we assessed expression of ZAP‐70…
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Craig R. Miller, Anna C. Nagel, LuAnn Scott et al. · 2016 · PeerJ
Parallelism is important because it reveals how inherently stochastic adaptation is. Even as we come to better understand evolutionary forces, stochasticity limits how well we can predict evolutionary outcomes. Here we sought to quantify…
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Fei Ke, Renbao Wang, Zihao Wang et al. · 2022 · Viruses
As nucleocytoplasmic large DNA viruses, replication of ranaviruses (genus Ranavirus, family Iridoviridae) involves a series of viral and host proteins. We have described that the replication and transcription machinery of Andrias…
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Zbigniew Putowski, Szymon Czajka, Łukasz J. Krzych · 2021 · Journal of Clinical Medicine
The recent consensus by the Perioperative Quality Initiative (POQI) on intraoperative hypotension (IOH) stated that mean arterial pressure (MAP) below 60–70 mmHg is associated with myocardial infarction (MI), acute kidney injury (AKI),…
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Sara Redenšek Trampuž, David Vogrinc, Katja Goričar et al. · 2023 · Frontiers in Molecular Neuroscience
Introduction Development and worsening of most common neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis, have been associated with COVID-19 However, the mechanisms associated with…
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Nam-Hee Kim, Ichiro Kawachi · 2020 · Scientific Reports
Abstract The Korean National Health Insurance expanded the dental insurance in 2012 to cover denture services for older adults. We analyzed whether the new policy improved of chewing ability in the eligible population. We used regression…
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Shuaiwen Wang, Haolei Weng, Arian Maleki · 2021 · Information and Inference: A Journal of the IMA
Abstract A recently proposed SLOPE estimator [6] has been shown to adaptively achieve the minimax $\ell _2$ estimation rate under high-dimensional sparse linear regression models [25]. Such minimax optimality holds in the regime where the…
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Marlene M. Moretti, Sebastian P. Dys, Stephanie G. Craig et al. · 2024 · JCPP Advances
Abstract Background Given the prevalence and recent increases in youth mental health problems, there is a pressing need for interventions that target transdiagnostic protective factors that could be targeted as mechanisms of change in…
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Alessio Malacrida, Marie Deschamps-Wright, Roberta Rigolio et al. · 2023 · International Journal of Molecular Sciences
Rigosertib is a small molecule in preclinical development that, due to its characteristics as a dual PLK1 and PI3K inhibitor, is particularly effective in counteracting the advance of different types of tumors. In this work, we evaluated…
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Susan M. Robertson, Shawn R. McGrath, Samuel Scarlett et al. · 2022 · Animal Production Science
Context Clinical deficiencies of calcium and magnesium may result in the metabolic disorders hypocalcaemia and hypomagnesaemia, resulting in ewe and lamb mortality. However, the contribution of subclinical deficiencies to perinatal lamb…
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Menghui Duan, Huanming Xiao, Meijie Shi et al. · 2024 · BMC Infectious Diseases
Abstract Background and aims Numerous HBeAg-positive chronic hepatitis B (CHB) patients with persistently normal ALT have significant liver histopathology. It is imperative to identify true “immune tolerant” patients. We aimed to evaluate…
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Fan Liu, Jordon Hogg, Susie Kracht et al. · 2019 · Animal Production Science
Context Lactoferrin is a non-haem binding protein that possesses antimicrobial, antioxidant and anti-inflammatory properties. A previous study showed lactoferrin supplementation from early gestation to weaning improved lactation…
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Kostas Iakovou, Kleopatra Schulpis · 2019 · International Journal of Adolescent Medicine and Health
Abstract Introduction Classical Phenylketonuria (PKU) is a metabolic disease characterized by high phenylalanine (phe) levels in blood and brain. PKU patients are commonly treated with low phe diet supplemented with amino acid free…
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John Devin Peipert, David Cella, Ron D. Hays · 2024 · Quality of Life Research
Abstract Interpretation of patient-reported outcome (PRO) scores has been supported by identifying score thresholds or ranges that indicate clinical importance. There has been a recent focus on the estimation of meaningful within patient…
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Emily E. Fay, Lindsay C. Czuba, Jennifer E. Sager et al. · 2021 · Therapeutic Drug Monitoring
Background: Bupropion (BUP) is a chiral antidepressant and smoking cessation aide with benefits and side effects correlated with parent and active metabolite concentrations. BUP is metabolized by CYP2B6, CYP2C19, and CYP3A4 to hydroxy-BUP…
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Kevin Butler, Benoît Forget, Stephen J. Heishman et al. · 2021 · Behavioural Pharmacology
Relapse is common amongst smokers attempting to quit and tobacco cue-induced craving is an important relapse mechanism. Preclinical studies commonly use cue-induced reinstatement of nicotine seeking to investigate relapse neurobiology.…
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Tania Ionin, Maria Goldshtein, Tatiana Luchkina et al. · 2021 · Linguistic Approaches to Bilingualism
Abstract This paper reports on an experimental investigation of what second language (L2) learners and heritage speakers of Russian know about the relationship between word order and information structure in Russian. The participants…
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Thomas Popp, Jonathan Mittaz · 2022 · Remote Sensing
The AVHRR aerosol optical depth (AOD) is inverted from measured reflectances in the red band using a statistical correlation of surface reflectance with mid-infrared channel reflectances and a modelling climatology of the aerosol type. For…
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Patrick Albers, Jacob Bennett, Moira Evans et al. · 2024 · Canadian Urological Association Journal
Introduction: Despite a negative magnetic resonance imaging (MRI), some patients may still harbor clinically significant prostate cancer (csPCa, Gleason grade group ≥2). High-resolution micro-ultrasound (microUS) is a novel imaging…
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Haili Yu, Tiejun Wang, Andrew Skidmore et al. · 2022 · Journal of Fungi
Fungi are a hyper-diverse kingdom that contributes significantly to the regulation of the global carbon and nutrient cycle. However, our understanding of the distribution of fungal diversity is often hindered by a lack of data, especially…
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Bukola Usidame, Gang Meng, James F Thrasher et al. · 2022 · Nicotine & Tobacco Research
Abstract Introduction Using a quasiexperimental design, we compared the impact of the 2000 Canadian introduction of graphic warning labels (GWLs) on differences in smoking prevalence by sex and education, to the United States, where no…
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Peng-Yi Lee, Jung-Nien Lai, Lu-Ting Chiu et al. · 2021 · PLOS ONE
Purpose This study aimed to determine the risk and time trends of herpes zoster among patients with head and neck cancer, with or without radiotherapy. Methods A total of 2160 patients with head and neck cancer were enrolled. The…
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