Negative / Null Result ReportOpen accessMedicine
Jie Wu, Jianan Ren, Qinjie Liu et al. · 2019 · Frontiers in Immunology
Background: Continuous veno–venous hemofiltration (CVVH) could influence immunomodulation by cytokine removal. Damage-associated molecular patterns (DAMPs) are released by injured cells and have roles in sepsis. We investigated if the magnitude of DAMPs removal was associated with mortality in patients with sepsis undergoing CVVH. Methods: We conducted a prospective, observational study on patients acquiring CVVH at department of surgery, Jinling Hospital. Circulating levels of DAMPs (mitochondrial DNA [mtDNA]; nuclear DNA [nDNA]; heat shock protein [HSP]70) and cytokines were measured at the
View details →Negative / Null Result ReportOpen accessMedicine
Tarek Mohamed Ashoor, Ahmad Mahmoud Hasseb, Ibrahim M. Esmat · 2020 · Korean journal of anesthesiology
Background: Nebulized heparin has been effectively used in the management of many pulmonary diseases. However, its effect on mechanically ventilated patients with acute exacerbation chronic obstructive pulmonary disease (AECOPD) has never…
View details →Negative / Null Result ReportOpen accessMedicine
Sarita Depani, Kondwani Joseph Banda, Simon Bailey et al. · 2015 · Pediatric Blood & Cancer
BACKGROUND: We previously reported a 28-day treatment protocol for children with endemic Burkitt lymphoma (BL) which included four doses of cyclophosphamide (CPM), intrathecal methotrexate and hydrocortisone (IT MTX/HC) at Queen Elizabeth…
View details →Negative / Null Result ReportOpen accessMedicine
Wen Sun, Yan Yang, Shidong Hu et al. · 2022 · Annals of Translational Medicine
Background: Patients in the intensive care unit (ICU) are often under stress and fail to cooperate well with invasive treatments. Analgesia and sedation are of great significance for reducing the suffering of patients and ensuring the…
View details →Negative / Null Result ReportOpen accessMedicine
Jayastu Senapati, Sanam Loghavi, Guillermo Garcia‐Manero et al. · 2024 · Haematologica
In myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) with TP53 aberrations, dissecting the interaction amongst patient, disease and treatment factors are important for therapeutic decisions and prognostication. This…
View details →Negative / Null Result ReportMedicine
Jae Hong Park, Isabelle Rivière, Xiuyan Wang et al. · 2017 · Journal of Clinical Oncology
7008 Background: CD19-specific chimeric antigen receptor (CAR) T cells have demonstrated high initial responses in patients with relapsed B-ALL. However, clinical characteristics associated with the durability of response remain undefined.…
View details →Negative / Null Result ReportOpen accessMedicine
Botao Ning, Sheng Ye, Yi Lyu et al. · 2020 · Translational Pediatrics
BACKGROUND: Sepsis has always been a challenge in pediatric intensive care unit (PICU) with poor prognosis. In order to evaluate the effect between routine continuous renal replacement therapy (CRRT) and high-volume hemofiltration (HVHF)…
View details →Negative / Null Result ReportOpen accessMedicine
Louise Katherine Bartolac, Jenna Lowe, George Koustas et al. · 2015 · Journal of Reproduction and Development
The aim of this study was to determine the optimum conditions for vitrifying in vitro produced day 7 porcine embryos using different vitrification devices and blastocoele collapse methods. Firstly embryos were collapsed by micro-pipetting,…
View details →Negative / Null Result ReportOpen accessMedicine
Moonkyoo Kong, Yu Jin Lim, Youngkyong Kim · 2018 · PubMed
Background: We conducted this study to contribute to resolving some controversial issues on management of nasopharyngeal carcinoma. Methods: Thirty-two patients with stage III-IVB nasopharyngeal carcinoma were included in this…
View details →Negative / Null Result ReportEngineering
Lukas Koedijk, Ana Oprescu · 2022
The EU Green Deal mirrors the societal concern regarding climate change. In the software industry this means reducing the energy consumption of a program. This can be done by looking both at the hardware and the software used. We take a…
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Attila Salamon, Stefania Uccheddu, Melitta Csepregi et al. · 2023 · Scientific Reports
Abstract The dog is a so far unique species to study interspecific communication and a promising evolutionary model for preverbal human communication. Recently cats were reported to show some similar skills to dogs. Here we directly…
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Jekaterina Kazantseva, Roman Ivanov, Michael Gasik et al. · 2016 · Scientific Reports
Abstract Three-dimensional (3D) customized scaffolds capable to mimic a native extracellular matrix open new frontiers in cells manipulation and advanced therapy. The major challenge is in a proper substrate for in vitro models on…
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Nicholas S. OSCROFT, Ian E. SMITH · 2010 · Respirology
ABSTRACT Background and objective: Volume‐assured non‐invasive positive pressure ventilation (va‐NIPPV) is a novel mode designed to adapt pressure support (PS) to achieve a target minute ventilation (TgV). This may optimize ventilation;…
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Endre Willassen, Jon-Ivar Westgaard, Jon Anders Kongsrud et al. · 2022 · PeerJ
To protect and restore ecosystems and biodiversity is one of the 10 challenges identified by the United Nations’s Decade of the Ocean Science. In this study we used eDNA from sediments collected in two fjords of the Svalbard archipelago…
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Yoshitaka Shimada, Yoshihito Takahashi, Hiroyoshi Iguchi et al. · 2013 · Journal of Medical Case Reports
Abstract Introduction Liver cavernous hemangioma is the most common noncystic hepatic lesion, and a hemangioma that undergoes degeneration and fibrous replacement is called a hepatic sclerosed hemangioma. Case presentation A 63-year-old…
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Lauren N. Forrest, Ross C. Jacobucci, Carlos M. Grilo · 2020 · Psychological Medicine
Abstract Background Eating-disorder severity indicators should theoretically index symptom intensity, impairment, and level of needed treatment. Two severity indicators for binge-eating disorder (BED) have been proposed (categories of…
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Jingran Zhang, Wukui Wang, Lei Gao et al. · 2022 · Atmosphere
Air pollution caused by coal burning not only increases the cost of environmental pollution but also harms human health. It is urgent for China to change the practice of coal-fired central heating. Therefore, the effectiveness and…
View details →Negative / Null Result Report
Shan Ren, Wenjing Wang, Junfeng Lu et al. · 2022 · Frontiers in Immunology
Objective In clinical practice, a substantial proportion of chronic hepatitis B virus (HBV) infections that do not fit into any of the usual immune states are considered to be in the “grey zone (GZ)”. This study aimed to investigate the…
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Juliana Chen, Harpreet Kaur, Joanna Jaques et al. · 2022 · Clinical Obesity
Summary Despite the obesity epidemic, there are relatively few multidisciplinary obesity services in Australia, and only limited data on the effectiveness of these services. The aim of this study was to evaluate the effectiveness of a…
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Aydin Demircioğlu · 2023 · Diagnostics
In radiomics, utilizing features extracted from pretrained deep networks could result in models with a higher predictive performance than those relying on hand-crafted features. This study compared the predictive performance of models…
View details →Negative / Null Result Report
Hao Huang, Wei Song, Xue‐Yan Liu · 2021 · Global Change Biology
Abstract Anthropogenic nitrogen (N) emissions and deposition have been increasing over past decades. However, spatiotemporal variations of N deposition levels and major sources remain unclear in many regions, which hinders making…
View details →Negative / Null Result ReportOpen accessMedicine
Caroline K. Kramer, Bernard Zinman, Haysook Choi et al. · 2017 · The Journal of Clinical Endocrinology & Metabolism
Context: Glucagon-like peptide-1 agonists acutely lower serum glucagon. However, in the Liraglutide and β-Cell Repair (LIBRA) Trial, 48-week treatment with liraglutide yielded lower/unchanged fasting glucagon but, surprisingly, enhanced…
View details →Negative / Null Result ReportPsychology
Alexander D. Stajković, Jessica M. Greenwald, Kayla Stajkovic · 2022 · Journal of Organizational Behavior
Summary The effects of primed money have received widespread attention in social psychology but not in the organizational literature. This research examines whether priming money causes people to think and behave in ways consistent with…
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Yiqun Xie, Xiaowei Jia, Shashi Shekhar et al. · 2021 · ACM Transactions on Intelligent Systems and Technology
Cluster detection is important and widely used in a variety of applications, including public health, public safety, transportation, and so on. Given a collection of data points, we aim to detect density-connected spatial clusters with…
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Kam Ng, Todd Sullivan · 2017 · Geotechnical Research
In Wyoming, pile foundations for bridges are often driven on rock materials because of the state’s shallow bedrock stratigraphy. Unfortunately, no static analysis methods are currently available for estimating the resistance of these…
View details →Negative / Null Result ReportSocial Sciences
Anthony N. Reffi, Caitlin M. Pinciotti, Holly K. Orcutt · 2018 · Journal of Interpersonal Violence
Institutional betrayal reflects the failings of a trusted institution to prevent or respond appropriately to negative experiences. Following sexual assault, survivors who encounter institutional betrayal may experience greater distress and…
View details →Negative / Null Result ReportOpen accessComputer Science
Joshua K. Hartshorne, Lauren Skorb, Sven L. Dietz et al. · 2019 · Collabra Psychology
We report the first set of results in a multi-year project to assess the robustness – and the factors promoting robustness – of the adult statistical word segmentation literature. This includes eight total experiments replicating six different experiments. The purpose of these replications is to assess the reproducibility of reported experiments, examine the replicability of their results, and provide more accurate effect size estimates. Reproducibility was mixed, with several papers either lacking crucial details or containing errors in the description of method, making it difficult to ascert
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Marian Dovgialo, Anna Chabuda, Anna Duszyk et al. · 2019 · International Journal of Neural Systems
Disorders of consciousness (DOC) are among the major challenges of contemporary medicine, mostly due to the high rates of misdiagnoses in clinical assessment, based on behavioral scales. This turns our attention to potentially objective…
View details →Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Olayemi O. Adeoye, Vincent Bouthors, Margaret C. Hubbell et al. · 2014 · Journal of Applied Physiology
Recent studies suggest that VEGF contributes to hypoxic remodeling of arterial smooth muscle, although hypoxia produces only transient increases in VEGF that return to normoxic levels despite sustained changes in arterial structure and…
View details →Negative / Null Result ReportBusiness, Management and Accounting
Subhankar Ghosh, Jayant Gupta, Arun Sharma et al. · 2022
Given a set S of spatial feature-types, its feature-instances, a study area, and a neighbor relationship, the goal is to find pairs such that C is a statistically significant regional colocation pattern in region rg. For example Caribou…
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